2
Cord blood education is now mandated in many states. For a complimentary consultation or to request more information, contact Cryo-Cell International at 800.786.7235 or [email protected] Regarding umbilical cord tissue, all private blood banks’ activities for New York State residents are limited to collection, processing, and long-term storage of umbilical cord tissue stem cells. The possession of a New York State license for such collection, processing and long-term storage does not indicate approval or endorsement of possible future uses or future suitability of these cells. In order to preserve more types and quantity of umbilical cord stem cells and to maximize possible future health options, Cryo-Cell’s umbilical cord tissue service provides expectant families with the opportunity to cryogenically store their newborn’s umbilical cord tissue cells contained within substantially intact cord tissue. Should umbilical cord tissue cells be considered for potential utilization in a future therapeutic application, further laboratory processing may be necessary. ©2015 Cryo-Cell International, Inc. All rights reserved. COT0198_0515D CORPORATE MISSION Cryo-Cell International’s mission is to provide our clients with the premier stem cell cryopreservation service and to support research and development initiatives for regenerative medicine. 800.786.7235 • Cryo-Cell.com Safeguarding The Future CORD BLOOD & CORD TISSUE MARY & RYAN SCHNEIDER’S STORY For close to a decade, nationally recognized Cryo-Cell Cord Blood Educator Mary Schneider has been championing the benefits of storing umbilical cord blood. But when she gave birth to her son, Ryan 12 years ago, she had no idea the turn her life would take. Although Mary’s pregnancy and Ryan’s birth were both completely normal, she began to notice that Ryan was experiencing some developmental challenges. Then, when Ryan was just a year old, she received the diagnosis that no parent ever wants to hear—he had a mild to moderate case of cerebral palsy. It’s not hard to imagine how this changed Mary’s world. However, she had had the foresight to store Ryan’s umbilical cord blood, and after extensive research, Mary found that cord blood could be used to treat cerebral palsy. In fact, in 2005 when Ryan was 3, he became the first child to receive his own cord blood at Duke University, in what is now an ongoing study for children with cerebral palsy that have access to their own cord blood. Ryan was cleared of all his symptoms shortly after his transplant and is a happy, healthy, 12 year-old today. “A brighter future is ahead for Ryan because I made the decision to bank his precious cord blood stem cells. Now many other children could also have the opportunity to live fuller lives when their parents make the same wise choice. Banking your child’s stem cells is the best insurance.” For more information contact Cryo-Cell International at 800.786.7235 or visit Cryo-Cell.com

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Cord blood education is now mandated in many states. For a complimentary consultation or

to request more information, contact Cryo-Cell International at

800.786.7235 or [email protected]

Regarding umbilical cord tissue, all private blood banks’ activities for New York State residents are limited to collection, processing, and long-term storage of umbilical cord tissue stem cells. The possession of a New York State license for such collection, processing and long-term storage does not indicate approval or endorsement of possible future uses or future suitability of these cells. In order to preserve more types and quantity of umbilical cord stem cells and to maximize possible future health options, Cryo-Cell’s umbilical cord tissue service provides expectant families with the opportunity to cryogenically store their newborn’s umbilical cord tissue cells contained within substantially intact cord tissue. Should umbilical cord tissue cells be considered for potential utilization in a future therapeutic application, further laboratory processing may be necessary. ©2015 Cryo-Cell International, Inc. All rights reserved. COT0198_0515D

Corporate MissionCryo-Cell International’s mission is to provide our clients with the premier stem cell cryopreservation service and to support research and development

initiatives for regenerative medicine.

800.786.7235 • Cryo-Cell.com

safeguarding the Future

Cord Blood & Cord tissue

Mary & ryan sChneider’s story

For close to a decade, nationally recognized Cryo-Cell Cord Blood Educator Mary Schneider has been championing the benefits of storing umbilical cord blood. But when she gave birth to her son, Ryan 12 years ago, she had no idea the turn her life would take.

Although Mary’s pregnancy and Ryan’s birth were both completely normal, she began to notice that Ryan was experiencing some developmental challenges. Then, when Ryan was just a year old, she received the diagnosis that no parent ever wants to hear—he had a mild to moderate case of cerebral palsy. It’s not hard to imagine how this changed Mary’s world. However, she had had the foresight to store Ryan’s umbilical cord blood, and after extensive research, Mary found that cord blood could be used to treat cerebral palsy.

In fact, in 2005 when Ryan was 3, he became the first child to receive his own cord blood at Duke University, in what is now an ongoing study for children with cerebral palsy that have access to their own cord blood. Ryan was cleared of all his symptoms shortly after his transplant and is a happy, healthy, 12 year-old today.

“A brighter future is ahead for Ryan because I made the decision to bank his precious cord blood stem cells. Now many other children could also have the opportunity to live fuller lives when their parents make the same wise choice. Banking your child’s stem cells is the best insurance.”

For more information contact Cryo-Cell International at

800.786.7235 or visit Cryo-Cell.com

Page 2: safeguarding the Future

Why Banking your BaBy’s Cord Blood is iMportant

Once considered medical waste, the umbilical cord is now helping families safeguard their future health. Cord blood is rich in hematopoietic stem cells, the building blocks of our blood and immune systems. Therapeutic uses for these cells are increasing.

2000

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02001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

All Cord Blood trAnsplAnts worldwide

the Cryo-Cell diFFerenCeFounded in 1989, Cryo-Cell International was the world’s first private cord blood bank to separate and store stem cells in 1992. Today, over 500,000 parents from 87 countries have entrusted Cryo-Cell International to help safeguard their families’ future health. Cryo-Cell International is the world’s leading cord blood bank for the following reasons:

•Cryo-Cell International is the industry’s most highly accredited cord blood bank.

•Cryo-Cell International is the first major cord blood bank to adopt the industry’s premium processing method, enabling parents to obtain the best possible cord blood collection for their babies2.

•Cryo-Cell International’s collection kit safeguards stem cells during transportation approximately 30 times longer than other private cord blood banks when exposed to extreme temperatures.

•100% of Cryo-Cell International’s specimens have been viable when thawed for therapeutic use. No other cord blood bank makes this statement.

•Cryo-Cell International, through its research affiliate, holds more cord blood patents than any other cord blood bank3.

•Cryo-Cell International uses the only FDA approved sterile collection bag.

•Cryo-Cell International’s $75,000 payment guarantee of cord blood engraftment is the best in the industry.

1 Nietfeld JJ, Pasquini MC, Logan BR, Verter F, Horowitz MM. Lifetime probabilities of

hematopoietic stem cell transplantation in the US. Biol Blood Marrow Transplant. 2008;14:316-22.

2Based on Cryo-Cell’s PrepaCyte CB processing technology. SLCBB data presented at the 16th Annual ISCT Meeting May 23-26, 2010. Henderson, C., et al., ISCT Annual Meeting, Philadelphia, PA, 2010. Alcaina, P., et al., EBMT Annual Meeting, Paris, France, 2011; Regan, D., et al., AABB Annual Meeting, San Diego, CA, 2011.

3Through our ownership in Saneron CCEL Therapeutics.

4Colony-forming units

For more information contact Cryo-Cell at 800.786.7235 or visit Cryo-Cell.com

Cord blood stem cells

have been used in over

30,000 transplants

worldwide to treat

illnesses including:

• Cancers

• immune system deficiencies

• genetic diseases

• Blood disorders

Today

superior proCessing teChnology

Cord blood and cord tissue

are currently being used in

many clinical trials to treat:

•Cerebral palsy

•autism

•heart disease

•diabetes

•alzheimer’s

•parkinson’s

•Cirrhosis of the liver

•sickle cell anemia

•ulcerative colitis

Tomorrow

•Umbilical cord blood stem cells are a perfect match for your baby and a close match for other family members

•Stem cells are being used to treat nearly 80 diseases including leukemia, lymphoma, immune deficiency and genetic disorders.

•The number of diseases currently being treated by stem cells has been increasing. The current odds of undergoing any stem cell transplant by age 70 is 1 in 2171.

•Leading scientists believe cord blood stem cells can be cryogenically stored indefinitely.

•Compared to bone marrow, cord blood stem cells are immunologically immature and less prone to produce graft versus host disease, have less risk of transmitting infection, are more easily matched to a recipient, have a potent graft versus tumor effect, and are more readily available in a shorter time period.

What does Cord tissue and the Future hold?

Cryo-Cell International also offers the storage of umbilical cord tissue, which is rich in mesenchymal stem cells. These cells give rise to structural tissues such as bone, cartilage and muscle and are currently being used in many clinical trials.

Cryo-Cell International recovers more healthy stem cells4 which means better therapeutic outcomes for your baby.

MOre Of what yOu want

less of what you don’t

Cryo-Cell International reduces red blood cell (RBC) contamination. Less red blood cells post processing means less toxic side effects.