A NEW LIBRARY FOR DRUG REPURPOSING

RESEARCH AREAS COVERED BY TOCRISCREEN FDA-APPROVED DRUG LIBRARY

Repurposing of approved drugs is key to accelerating drug development for both common and rare diseases. By finding a new indication for an ‘old’ drug, the risk of failure is lower as the compounds has already been proven sufficiently safe in pre-clinical and clinical models. The new Tocriscreen FDA-Approved Drugs Library (Cat. No. 7200) provides you with compounds for a diverse range of targets and therapeutic areas, for your in vitro and in vivo drug repositioning studies.

• 190 compounds equivalent to pharmacologically active components of FDA-approved drug formulations

• Supplied pre-dissolved in DMSO (10 µL 10 mM solutions)

• Covers a diverse range of therapeutic classes and research areas

• Includes established therapeutics and recently approved compounds, such as darunavir and sorafenib

• Compounds have the same proven solubility, purity and stability as all Tocris compounds

• Fully chemical and biological data available

For futher information and to request a compound list, please visit | tocris.com/screening

ENDOCRINOLOGY 11%

CARDIOVASCULAR 16%

IMMUNOLOGY 6%

OTHER 3%

STEM CELLS 3%

NEUROSCIENCE 34%

CANCER 27%

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For research use or manufacturing purposes only. Trademarks and registered trademarks are the property of their respective owners.

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Tubes

Your own tubes Tocris-provided tubes

CUSTOMIZE

Format

In solution(10 mM in DMSO)

50 µL to 1 mL 2 to 10 mg

Dry

Compounds

Select your ownlist of compounds

Specify your target family/research area

PRO

OTHER COMPOUND LIBRARIES FROM TOCRIS

TOCRISCREEN PRO - A UNIQUE CUSTOM COMPOUND LIBRARY SERVICE

The Tocriscreen Compound Library range includes collections of bioactive compounds designed for use in assays for target valida-tion, tool compound identification, assay development and drug repurposing.

TOCRISCREEN 2.0 A library of 1280 biologically active compounds, available in three different size formats:

• Tocriscreen 2.0 Micro (Cat. No. 7152) - 15 μL 10 mM DMSO solutions

• Tocriscreen 2.0 Mini (Cat. No. 7151) - 50 μL 10 mM DMSO solutions

• Tocriscreen 2.0 Max (Cat. No. 7150) - 250 μL 10 mM DMSO solutions

TOCRISCREEN EPIGENETICS LIBRARY (CAT. NO. 6801) A library of 101 epigenetic compounds, 250 μL 10 mM DMSO solutions. Contains compounds covering >40 epigenetic readers, writers, erasers and transcriptional modulators.

TOCRISCREEN KINASE INHIBITOR TOOLBOX (CAT. NO. 6268) A library of 157 kinase inhibitors, 250 μL 10 mM DMSO solutions. Contains compounds targeting >60 different kinases, include established (e.g. VEFGR, AKT) and novel (e.g. LIMK, DYRK) targets.

TOCRISCREEN STEM CELL TOOLBOX (CAT. NO. 5060) A library of 80 stem cell modulators, 250 μL 10 mM DMSO solutions.

The Tocriscreen PRO service enables you to cherry-pick compound to create a custom library designed to meet your exact screening requirements. The Tocris scientific team can provide assistance with choosing compounds that are relevant to your research.

Contact us to discuss your needs - www.tocris.com/tocriscreenlist