A cardiac action potential …

Summation

Summation

Lecture Outline• From passive to active membrane

properties• The action potential• Effect of myelination• Refractory periods• NBME priming• Synapses

ChemicalElectrical

The Voltage-Gated Sodium Channel

Inactivation of Voltage-Gated Na+ Channels

Inactivating particle

Gate

Inactivation of Voltage-Gated Na+ Channels

Inactivation of Voltage-Gated Na+ Channels

Inactivation of Voltage-Gated Na+ Channels

Refractory Periods

Lecture Outline• From passive to active membrane

properties• The action potential• Effect of myelination• Refractory periods• NBME priming• Synapses

ChemicalElectrical

Chemical Synapse

Synaptic Vesicle Dynamics

Fluorescent Labeling of Connexin 43