48
Anne Cees Houtman UZ-VUB REFRACTION IN CHILDREN

REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

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Page 1: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Anne Cees

Houtman

UZ-VUB

REFRACTION IN

CHILDREN

M 7 days old 3640

Hyperextensibility joints

Mild retrognathia

Request eye assessment

What are you going to do

11-2-2014 refraction in children 2

WARD REFERRAL

Schisiservaringennl

Externally normal

Clear media

Normal fundi

11-2-2014 refraction in children 3

WARD REFERRAL

Schisiservaringennl

A little history

What determines refraction

What is normal

The 5Wrsquos of refraction

Refractive error

A treatable condition Guidelines for prescribing

Refractive surgery in children

A bonus refraction as a differential diagnostic sign

Refract ion in

chi ldren

11-2-2014 refraction in children 4

OUTLINE

11-2-2014 refraction in children 5

A LITTLE

HISTORY

Tommaso da Modena Treviso

2112014 Refraction in children 6

KEPLER EN DESCARTES

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 2: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

M 7 days old 3640

Hyperextensibility joints

Mild retrognathia

Request eye assessment

What are you going to do

11-2-2014 refraction in children 2

WARD REFERRAL

Schisiservaringennl

Externally normal

Clear media

Normal fundi

11-2-2014 refraction in children 3

WARD REFERRAL

Schisiservaringennl

A little history

What determines refraction

What is normal

The 5Wrsquos of refraction

Refractive error

A treatable condition Guidelines for prescribing

Refractive surgery in children

A bonus refraction as a differential diagnostic sign

Refract ion in

chi ldren

11-2-2014 refraction in children 4

OUTLINE

11-2-2014 refraction in children 5

A LITTLE

HISTORY

Tommaso da Modena Treviso

2112014 Refraction in children 6

KEPLER EN DESCARTES

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 3: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Externally normal

Clear media

Normal fundi

11-2-2014 refraction in children 3

WARD REFERRAL

Schisiservaringennl

A little history

What determines refraction

What is normal

The 5Wrsquos of refraction

Refractive error

A treatable condition Guidelines for prescribing

Refractive surgery in children

A bonus refraction as a differential diagnostic sign

Refract ion in

chi ldren

11-2-2014 refraction in children 4

OUTLINE

11-2-2014 refraction in children 5

A LITTLE

HISTORY

Tommaso da Modena Treviso

2112014 Refraction in children 6

KEPLER EN DESCARTES

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 4: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

A little history

What determines refraction

What is normal

The 5Wrsquos of refraction

Refractive error

A treatable condition Guidelines for prescribing

Refractive surgery in children

A bonus refraction as a differential diagnostic sign

Refract ion in

chi ldren

11-2-2014 refraction in children 4

OUTLINE

11-2-2014 refraction in children 5

A LITTLE

HISTORY

Tommaso da Modena Treviso

2112014 Refraction in children 6

KEPLER EN DESCARTES

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 5: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

11-2-2014 refraction in children 5

A LITTLE

HISTORY

Tommaso da Modena Treviso

2112014 Refraction in children 6

KEPLER EN DESCARTES

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 6: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

2112014 Refraction in children 6

KEPLER EN DESCARTES

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 7: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

2112014 Refraction in children 7

SETTLED OPINIONS AND IGNORANCE

ldquothe mad fashion of wearing glassesrdquo against which we

ldquocannot warn too insistentlyrdquo

(Jaeger 1855)

Young persons wearing glasses were

ldquolooked on as dudesrdquo

(Hoyer 1836)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 8: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

2112014 Refraction in children 8

SCIENTIA TENEBRAS VINCERE

ldquoPhysiological opticsrdquo

(Helmholtz 1856)

ldquoAccommodation and refraction of the eyerdquo

(Donders 1864)

ldquoSkiascopy and its practical applications to the Study of

Refractionrdquo

(Jackson 1895)

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 9: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

11-2-2014 Refraction in children 9

WHAT

DETERMINES

REFRACTION

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 10: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

11-2-2014 10

ORGANOGENESIS

FOXC1

PITX2 neural crest

LMX1B

FOXE3 lens

MAF

CYP1B1 gt P450 enzyme

PAX6

Refraction in children

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 11: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 11

Cornea

Lens

Axial length

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 12: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 12

Cornea

Lens

Axial length

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 13: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Genetics Environment

11-2-2014 Refraction in children

Twin studies

Parental refraction

Ethnicity

E-Asia S-Asia Eur Afr

Hereditary conditions

Visual input

Peripheral retinal defocus

Accommodation

Daylight hours

Education

Geography

Social-economic status

Outdoor activity

LBWIUGR

Maternal ageheight

Cigarettes

Height at adult age

13

DEVELOPMENT OF REFRACTION

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 14: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

11-2-2014 Refraction in children 14

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 15: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

11-2-2014 Refraction in children 15

ABNORMAL DEVELOPMENT WILL AFFECT REFRACTION

Matta NS Silbert DI High prevalence of amblyopia risk factors in

preverbal children with nasolacrimal duct obstruction JAAPOS 2011

Aug15(4)350-2

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 16: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHATrsquoS NORMAL

11-2-2014 Refraction in children 16

Text book of ophthalmology Vol IV Errors of refraction p4247 W Stewart Duke-Elder Henry Kimpton London

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 17: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHATrsquoS NORMAL

11-2-2014 Refraction in children 17

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 18: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHATrsquoS NORMAL

11-2-2014 Refraction in children 18

The prevalence of refractive errors among children adolescents and adults in Germany Jobke s et al Clin Ophthalmol 2008 (2) 3 601-7

N=536

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 19: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Who

What

Where

When

Why

11-2-2014 19 refraction in children

THE 5 WrsquoS OF

REFRACTION

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 20: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHO IS GOING TO DO

IT

11-2-2014 refraction in children 20

THE 5 WrsquoS

OF

REFRACTION

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 21: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 21

THE 5 WrsquoS

OF

REFRACTION

ldquoEVERY CHILD HAS THE RIGHT OF A

CYCLOPLEGIC REFRACTIONrdquo

wwwcommunityniorg

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 22: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHO IS GOING TO

HAVE IT DONE

11-2-2014 refraction in children 22

THE 5 WrsquoS

OF

REFRACTION

And remember

ldquoCycloplegic drops ought to be used as if they

were freerdquo

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 23: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 23

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 24: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 24

THE 5 WrsquoS

OF

REFRACTION ldquoIt is however an art which cannot be learned

from books for efficiency can only be attained

by long assiduous and painstaking practicerdquo

Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4377

Bowman 1859 CuignetMenginLandolt 1878 Parent 1880

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 25: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 25

THE 5 WrsquoS

OF

REFRACTION

Retinoscopy simulators

wwweyeontechscom

wwwmrcophthcom ndash test yourself

wwwmedroundorg - $$

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 26: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 26

THE 5 WrsquoS

OF

REFRACTION

Autorefractors

Retinomax

Plusoptix

Edinburghoptometryca

wwwcalcoastophthalmiccom

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 27: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 27

THE 5 WrsquoS

OF

REFRACTION

Retinomax

Comparison of the Retinomax autorefractor with hand-held retinoscopy in 1-year old infants

Gole GA et al Clinical and Experimental Ophthalmology 2003 31 341-347

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 28: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 28

THE 5 WrsquoS

OF

REFRACTION

Plusoptix

N=118 mean age 5

Plusoptix S08 -005 plusmn 161

Cycloplegic retinoscopy -015 plusmn 131

Cycloplegic AR -012 plusmn 141

Int Ophthalmol 2013 Oct 10 [Epub ahead of print]- abstract

Comparison of photorefraction autorefractometry and retinoscopy in children

Demirci G Arslan B Ozsuumltccediluuml M Eliaccedilık M Gulkilik G

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 29: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

UZ-VUB

2013

N=58 ( p r e l i m i n a r y r e s u l t s )

11-2-2014 refraction in children 29

PLUSOPTIX

RETINOMAX

AR amp

RETINOSCOPY

Average non-cyclo ARRM seq RE -005

Average non-cyclo Plusoptix +013

Average cyclo ARRM

+054

And then we found the autorefractors and

retinoscopy may disagree by 275 D (spherical power) in some cases

And 175D for cylindershellip

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 30: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 30

THE 5 WrsquoS

OF

REFRACTION

ldquoRetinoscopy is the most generally satisfactory and accurate

method for the objective determination of the refractionrdquo Textbook of ophthalmology Duke-Elder S Vol IV London Henry Kimpton 1950 p4386

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 31: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 31

THE 5 WrsquoS

OF

REFRACTION

ldquoYour best friendrdquo (D Taylor) Snellen and Landolt 1874

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 32: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHAT ARE YOU GOING

TO DO

11-2-2014 refraction in children 32

THE 5 WrsquoS

OF

REFRACTION

Cycloplegia

atropine 1h 2w

cyclopentolate 30-60rsquo 48h

tropicamide 20-30rsquo 6h

Residual accommodation (6-12 yrs) tropicamide +047 D than cyclopentolate

(Mutti ea The effect of cycloplegia on measurement of the ocular components IOVS 1994)

Residual accommodation may be as much as 2D more than atropine according

to several authors

side effects hypersensitivity reactions fever dry mouth rapid pulse nausea vomiting

flushing and rarely behavioral changes

(several dozen case reports over a century ndash so probably safe)

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 33: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHERE ARE YOU GOING

TO DO IT

11-2-2014 refraction in children 33

THE 5 WrsquoS

OF

REFRACTION

Well anywhere reallyhellip

hellipas long as you do it

httptelemedicineorbisorg

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 34: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHEN

11-2-2014 refraction in children 34

THE 5 WrsquoS

OF

REFRACTION

First visit

Check yearly

Frequently pseudophakiaaphakia glaucoma

eyelid lesions

Decrease in VA

Intolerance to glasses

Change in squint angle

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 35: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHY

11-2-2014 refraction in children 35

THE 5 WrsquoS

OF

REFRACTION

Importance of vision for general development

Poor growthdevelopment may be associated

with visual problems

And think of refractive error as

a treatable condition (glasses have very few side effects)

a differential diagnostic sign

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 36: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Guidelines

for

prescribing

11-2-2014 refraction in children 36

A

TREATABLE

CONDITION

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 37: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Cont roversy

abounds

11-2-2014 refraction in children 37

PRESCRIBING

WHAT

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 38: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

RCOphth

Not found

recent ly on

website

11-2-2014 refraction in children 38

PRESCRIBING

WHAT

Anisometropia hypermetropia 150

astigmatism 200

myopia 200

Isometropia hypermetropia 450

myopia 300

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 39: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

AAO

A gain hard to

f ind the

guidel ines

11-2-2014 refraction in children 39

PRESCRIBING

WHAT

hyperopia (no tropia) gt +450D

hyperopia with esotropia gt +150D

astigmatism gt 200D

anisohyperopia gt 150D

myopia gt 200D

astigmatism gt 200D

myopia gt -300D

wwwaaoorgeducationlibrarypppindexcfm

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 40: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

MYOPIA

11-2-2014 myopie op de kinderleeftijd 40

Undercorrect or fully correct

The Cochrane Col laborat ion

Interventions to slow progression of myopia in children W a l l i n e J J L i n d s l e y K V e d u l a S S C o t t e r S A M u t t i D O T w e l k e r J D

ldquoLimited evidence favoring ful l correct ionrdquo

Undercorrection of myopia enhances rather than inhibits myopia progression Chung

K V is ion Res 2002422555 -9

The possible effect of undercorrection on myopic progression in children Adler D et

a l C l in Exp Optom 2006 Sep89(5) 315 -21

ldquoConsistent evidence of meaningful benefit with ant i -muscarinic drugs rdquo

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 41: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

HYPERMETROPIA

11-2-2014 myopie op de kinderleeftijd 41

Accommodation convergence strabismus asthenopia

Well-known since the mid-19 th century but neglected often

Strongly consider partial or full correction in non-strabismic

hypermetropia eg gt +45 D (risk of ametropic amblyopia)

Full correction in strabismus

Hypermetropic correction does not influence emmetropization

I n f a n t H y p e r o p i a D e t e c t i o n D i s t r i b u t i o n C h a n g e s a n d C o r r e l a t e s mdash O u t c o m e s F r o m t h e C a m b r i d g e I n f a n t S c r e e n i n g P r o g r a m s

A t k i n s o n J e t a l O p t o m e t r y a n d V i s i o n S c i e n c e 2 0 0 7 8 4 8 4 ndash 9 6

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 42: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

Ver y

cont roversial

11-2-2014 refraction in children 42

REFRACTIVE

SURGERY IN

CHILDREN

Refractive surgery may be

considered in

High anisometropia and isoametropia

associated with amblyopia when standard

treatment fails

Neurobehavioural disorders

Techniques corneal refractive surgery

intraocular surgery

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 43: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

11-2-2014 refraction in children 43

eg

Phakic intraocular lens correction of high ametropia in children with neurobehavioural

disorders Tychsen L Hoekel J Ghasia F Yoon-Huang G Journal of AAPOS 200812282-289

Preop -2275 to -100 D (-149 D N=11 18 eyes)

Directly postop -03 D(+-11)

Regression +06 D (+-15D)

Postop +02 D (+- 08)

Preop UCVA 203400 (logMAR 223 +-057)

Postop UCVA 2057 (logMAR 046 +- 028)

60 x

T-test p=000

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 44: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHY

11-2-2014 refraction in children 44

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High hypermetropia

Leber congenital amaurosis

Achromatopsia

Nanophthalmus

Cornea plana

Microphthalmia

XLRS

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 45: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHY

11-2-2014 refraction in children 45

THE 5 WrsquoS

OF

REFRACTION

A differential diagnostic sign

High myopia

CSNB

Congenital glaucoma

Megalocornea

FAS

Stickler

Stargardt

Gyrate Atrophy

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 46: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

2112014 Refraction in children 46

What about that ward referral

Brother RE -12 LE -10

vitreous lacunae

high arched palate gtgt Stickler

Baby +3 +3

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 47: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

2112014 Refraction in children 47

SOhellip

Think refraction

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom

Page 48: REFRACTION IN Anne Cees Houtman CHILDREN UZ …...retinoscopy -0.15 ± 1.31 Cycloplegic AR -0.12 ± 1.41 Int Ophthalmol. 2013 Oct 10. [Epub ahead of print]- abstract Comparison of

WHYhellip

BECAUSE WE HAVE TO

2112014 Refraction in children 48

REFRACTION IN CHILDREN

littlefoureyescom