Quiz2ReviewKris.neKra1s,M.D.

Quiz2Review

•  ImmunologyOverview

•  Hypersensi.vity

•  ImmuneLabTests

Quiz2Review

•  ImmunologyOverview

classIMHCmoleculeclassIIMHCmolecule

class II MHC genes class I MHC genes class III MHC genes

MHCcomplex

class II MHC genes class I MHC genes class III MHC genes

MHCgenesarepolymorphic!

class II MHC genes class I MHC genes class III MHC genes

MHCgenesarepolymorphic=manynormalvariants!

Quiz2Review

•  ImmunologyOverview

•  Hypersensi.vity

TypeI:Allergy

Opsoniza.onandphagocytosis

TypeII:An.body

TypeIII:Immunecomplex

Delayed-TypeHypersensi.vity(DTH)

T-cell-mediatedcytotoxicity

TypeIV:T-cell

Quiz2Review

•  ImmunologyOverview

•  Hypersensi.vity

•  ImmuneLabTests

patient red cells + AHG = agglutination

patient Ab + AHG = agglutination donor

RBC = Ab-coated donor RBC +