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Part I: 14 July 2011 Toronto Rehab 550 University Ave. Manolo Romero Escobar http://mixedReviews.wordpress.com 14/07/2011 1 Quantitative Data Analysis for Health Research

Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

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Page 1: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Part I: 14 July 2011

Toronto Rehab

550 University Ave.

Manolo Romero Escobar

http://mixedReviews.wordpress.com

14/07/20111

Quantitative Data Analysis

for Health Research

Page 2: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Your type of question

14/07/20112

Descriptive

Relational

Causal

Page 3: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Your type of design

14/07/20113

Passive-Observational

Quasi-experimental

Experimental

Page 4: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Types of experimental designs

14/07/20114

Type Observation Treatment Observation Treatment Observation

Basic: X O

O

Factorial X(A1B1)

X(A1B2)

X(A2B1)

X(A2B2)

O

O

O

O

Pre-test

Post-test

O

O

X O

O

Solomon Four

Group

O

O

X

X

O

O

O

O

Switching

Replications

O

O

X O

O X

O

O

Crossover O

O

X(A)

X(B)

O

O

X(B)

X(A)

O

O

Longitudinal O...O X O. O...O

Page 5: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Types of control groups

14/07/20115

Placebo Expectancy Wait-list

AttentionNo-

Attention

Page 6: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Sampling and the sampling distribution

Central Limit Theorem Applet

http://www.cs.uic.edu/

~wilkinson/Applets/clt.

html

14/07/20116

Page 7: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Levels of SES

Treatm

en

t C

on

dit

ions

+++

+

+

++ ++

+

++

+

+

+

+

+

+

+

+

++

+

++

++

+

+

+

++

+

+

+

+

+

++

+

++

+

+

+

+

++++ +

+

++ +

+

++

+

+++

+

+

+

+ ++

++

+

+

+

+

+

+

+

+

+

+

+

+

+ +

+++ +

+++ +

+

+

+

+

+

+

++ ++

++

+

++

+

+

+

+

+

+

+++

+

+ ++

Control Emotion Focus Empowrmnt

46

810

12

14

Self

-Est

eem

Treatment Condition

5 10 15 20

46

810

12

14

Resilience)

Self

-Est

eem

Categorical variables

Testing mean differences of a continuous variable

between groups (categorical variable)

Continuous variables

7

Page 8: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Mean contrast & ANOVA

14/07/20118

2 groups: t-test

Independent Samples

Repeated Measures

k groups: ANOVA

One way ANOVA

One-way Repeated Measures

Factorial (e.g. 2x2)

Repeated Measures Factorial

Page 9: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Extensions to the factorial design

14/07/20119

• Levels as in T1, T2, control.

• Factors: Main effects: A, B, C

• Interactions: AB, AC, BC, ABC

Add levels/factors

• Non-random (e.g. Gender) factor

• Sometimes better to use ANCOVA (GLM)

Blocking factor

• Within-Between effects

• Issues with assumptions: homogeneity of variance (sphericity)

• Corrections: Geisser-Greenhouse & Huynh-Feldt.

Repeated measures

factor

Page 10: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

ANOVA, ANCOVA, Regression,χ2

14/07/201110

Method Dependent Independent

ANOVA Continuous Categorical

ANCOVA Continuous At least one

categorical and

one continuous

Multiple

Regression (MR)

Continuous

(linear) or

categorical (e.g.,

logistic)

Continuous or

categorical

(dummy coded)

χ2 test of

independence

Categorical Categorical

Page 11: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Parametric Effect Size Indexes

From Kline 2004

Links on the website:

http://mixedreviews.wordpress.com/2011/07/13/quantitative-data-analysis-part-i/

14/07/201111

Page 12: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

G*Power 3

http://www.psycho.uni-

duesseldorf.de/abteilung

en/aap/gpower3

14/07/201112

Page 13: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

G*Power 3: Mean contrasts

14/07/201113

�One group:

�Difference from constant

� Two groups:

�Two dependent groups, matched pairs

�Two independent groups

�Many groups:

�ANOVA: One-way (one independent variable)

�ANOVA: Main effects and interactions (two or

more independent variables)

Page 14: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

14/07/201114

Page 15: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Exercise 1: t-testt-test: Independent

samples

14/07/201115

� Calculate sample size with

the parameters presented

� Plot sample size (y axis) as

a function of effect size

(use values of d from .2 to

.8)

Page 16: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

14/07/201116

Tota

l sam

ple

siz

e

Page 17: Quantitative Data Analysis for Health Research · Independent Samples Repeated Measures k groups: ANOVA One way ANOVA One-way Repeated Measures Factorial (e.g. 2x2) Repeated Measures

Exercise 2: F test

14/07/201117

DV: Self Esteem

Treatment

Groups

mean sd n

Control 7.63 1.50 40

Emotion Focus 11.43 2.11 40

Empowerment 9.73 1.75 40

SES Groups mean sd n

low 8.84 2.36 32

medium 9.66 2.32 59

high 10.28 2.34 29

� One way ANOVA omnibus

test

� Estimate the effect size for

each IV groups

� With power of .80

determine sample size