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Drugs and You ASSIGNMENT. Professor Dr. Nafeeza Mohd Ismail M.B.B.S.(Mal), Ph.D (UKM) Professor of Pharmacology Faculty of Medicine UiTM. Common terminologies. Indications Contra indications drug can’t be given to patient Absolute contraindication - PowerPoint PPT Presentation
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Professor Dr. Nafeeza Mohd Ismail
M.B.B.S.(Mal), Ph.D (UKM)Professor of Pharmacology
Faculty of MedicineUiTM
Drugs and YouASSIGNMENT
Indications Contraindications
drug can’t be given to patient
Absolute contraindication Definitely cannot be given as it has a high
risk of causing harm to patient
Relative contraindication Drug can be given with specific cautions
Common terminologies
Tolerance - a reduced response to a drug after
repeated administration of that drug. - larger doses must be given to get the
same magnitude of effect. - not with all drugs- very important with certain drugs
Common terminologies
Drug nomenclature
Chemical name: - N-acetyl-para-amino phenol
1.**Generic name** - Paracetamol
2. Trade/Proprietary name – Panadol, Tylenol etc.
Classification of drugs based on:
MOA: COX inhibitors
Organ system that it affects: CNS drugs, GIT drugs etc
Uses – anti-inflammatories, analgesics, bronchodilators
Routes of administration
Principles in Administering Medications
“5 Rights” of drug administration Right drug Right dose Right time Right patient Right route
Routes of administration - objectives
To describe the various routes of drug administration
To understand the advantages and disadvantages of the various routes of drug administration
Routes of administration
Routes of administration Enteral
enteral means to do with the GIT (gastrointestinal tract)
includes oral, buccal, and rectal.
Parenteral Not through the GIT Common routes - IV, IM, SC; but could also
include topical and inhalation.
Special – intravenous (i/v) Does not need to cross any membrane (skips
absorption process)
Oral - Advantages
Advantages Convenient (Relatively) Cheap Variety Conscious etc. Disadvantages
http://www.boomer.org/c/p1/Ch07/Ch0702.html
Buccal/Sublingual Buccal tablets
held in mouth designed to dissolve slowly.
Sublingual tablet under the tongue rapidly absorbed. e.g. nitroglycerin may be used for the rapid relief
of angina.
Advantages: Disadvantages:
http://www.boomer.org/c/p1/Ch07/Ch0703.html
Rectal Most commonly - suppository or enema. Advantages: Disadvantages:
http://www.boomer.org/c/p1/Ch07/Ch0703.html
IntravenousDrugs may be given into a peripheral vein over 1 to 2 minutes or longer by infusion.
Advantages: Rapid - quick response
possible Total dose - delivered
blood stream. doses – infusion.
Disadvantages: Difficult to find suitable
vein. Toxicity a problem with
rapid administrations.
Diagram - Showing IV, IM, and SC Injectionhttp://www.boomer.org/c/p1/Ch07/Ch0704.html
Subcutaneous and Intramuscular
Subcutaneous This involves
administration of the drug dose just under the skin.
Intramuscular Larger volume, than
sc, can be given by IM
Advantages:
Disadvantages:
http://www.boomer.org/c/p1/Ch07/Ch0705.html
Other ROA – what it means &when is it used
• Inhalation
• Topical
• Other ROA's
• intra-nasal
• intra-arterial
• intrathecal
• http://www.boomer.org/c/p1/Ch07/Ch0706.html