POSTER PRESENTATION Open Access Prevalence of HBV and HIV coinfection from an infectious disease hospital in Mumbai Jayanthi Shastri * , Nita Gangurde, Manish Pathak, Sandhya Sawant, Sachee Agrawal From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. 30 January - 1 February 2014 Background Hepatitis B virus (HBV) and HIV coinfection are pressing health problems in developing countries including India. Concurrent infection with HBV may alter the natural his- tory and treatment of both diseases. Hepatitis B and HIV frequently coexist due to common modes of transmission. HIV and HBV coinfection leads to complex immuno- pathological disorder heralding poor prognosis and dismal outcomes. The present study was aimed to examine the prevalence of HIV and HBV coinfection among hospitalized patients. Methods Two groups of population were studied; group I (n=1000) hospitalized adult patients with clinical jaundice were tested for HBsAg by ELISA. HBsAg positive patients were further tested for HIV infection as per NACO guidelines. Group II (n= 650) hospitalized patients with symptoms like fever > 1month, weight loss >10%, cough >3 weeks and lymphadenopathy were tested for HIV as per NACO guidelines. HIV positive patients were further tested for HBsAg by ELISA. Results In group I, 10 % were positive for HBsAg and out of 100 HBsAg positive 6% were co infected with HIV. In group II, 15.38% were positive for HIV and out of 100 HIV positive 25% were co- infected with HBV. Overall co infection is 15.5% with male preponderance and heterosexual mode of transmission being the commonest. Conclusion HIV and HBV share common modes of transmission, therefore all HIV positive patients should be screened for HBV coinfection. Guidelines should be modified to include mandatory HBV testing among HIV positive indi- viduals to monitor progress of infection and improve treatment outcomes. Published: 27 May 2014 doi:10.1186/1471-2334-14-S3-P11 Cite this article as: Shastri et al.: Prevalence of HBV and HIV coinfection from an infectious disease hospital in Mumbai. BMC Infectious Diseases 2014 14(Suppl 3):P11. Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • Thorough peer review • No space constraints or color ﬁgure charges • Immediate publication on acceptance • Inclusion in PubMed, CAS, Scopus and Google Scholar • Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit * Correspondence: [email protected] Department of Microbiology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India Shastri et al. BMC Infectious Diseases 2014, 14(Suppl 3):P11 http://www.biomedcentral.com/1471-2334/14/S3/P11 © 2014 Shastri et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Prevalence of HBV and HIV coinfection from an infectious disease hospital in Mumbai

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Page 1: Prevalence of HBV and HIV coinfection from an infectious disease hospital in Mumbai

POSTER PRESENTATION Open Access

Prevalence of HBV and HIV coinfection from aninfectious disease hospital in MumbaiJayanthi Shastri*, Nita Gangurde, Manish Pathak, Sandhya Sawant, Sachee Agrawal

From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014)Chennai, India. 30 January - 1 February 2014

BackgroundHepatitis B virus (HBV) and HIV coinfection are pressinghealth problems in developing countries including India.Concurrent infection with HBV may alter the natural his-tory and treatment of both diseases. Hepatitis B and HIVfrequently coexist due to common modes of transmission.HIV and HBV coinfection leads to complex immuno-pathological disorder heralding poor prognosis and dismaloutcomes. The present study was aimed to examine theprevalence of HIV and HBV coinfection among hospita-lized patients.

MethodsTwo groups of population were studied; group I (n=1000)hospitalized adult patients with clinical jaundice weretested for HBsAg by ELISA. HBsAg positive patientswere further tested for HIV infection as per NACOguidelines. Group II (n= 650) hospitalized patients withsymptoms like fever > 1month, weight loss >10%, cough>3 weeks and lymphadenopathy were tested for HIV asper NACO guidelines. HIV positive patients were furthertested for HBsAg by ELISA.

ResultsIn group I, 10 % were positive for HBsAg and out of 100HBsAg positive 6% were co infected with HIV. In group II,15.38% were positive for HIV and out of 100 HIV positive25% were co- infected with HBV. Overall co infection is15.5% with male preponderance and heterosexual mode oftransmission being the commonest.

ConclusionHIV and HBV share common modes of transmission,therefore all HIV positive patients should be screened

for HBV coinfection. Guidelines should be modified toinclude mandatory HBV testing among HIV positive indi-viduals to monitor progress of infection and improvetreatment outcomes.

Published: 27 May 2014

doi:10.1186/1471-2334-14-S3-P11Cite this article as: Shastri et al.: Prevalence of HBV and HIV coinfectionfrom an infectious disease hospital in Mumbai. BMC Infectious Diseases2014 14(Suppl 3):P11.

Submit your next manuscript to BioMed Centraland take full advantage of:

• Convenient online submission

• Thorough peer review

• No space constraints or color figure charges

• Immediate publication on acceptance

• Inclusion in PubMed, CAS, Scopus and Google Scholar

• Research which is freely available for redistribution

Submit your manuscript at www.biomedcentral.com/submit

* Correspondence: [email protected] of Microbiology, TN Medical College and BYL Nair CharitableHospital, Mumbai, India

Shastri et al. BMC Infectious Diseases 2014, 14(Suppl 3):P11http://www.biomedcentral.com/1471-2334/14/S3/P11

© 2014 Shastri et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative CommonsAttribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction inany medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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