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Presentation of Scientific ResultsGUF - the Group of Young Researchers
Hvidovre Hospital – 18. marts 2014
Disclaimer:The publications, slides, data and studies mentioned in this presentation is only used as examples of communication and form. It is not intended to evaluate contents, data, texts, conclusions, publications or similar. Words as ‘dull’ and ‘interesting’ are my terms only and are not referring to the authors work. The terms should be seen in the light of the purpose of this presentation: to tell the interesting story.
Focus for this presentation
• Introduction & Goal
• Impact of scientific presentations!
•A model
•Examples & Hints
•Promotion !
• Summing up
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Goal for this session
•You can• benefit from examples and hints from now on• benefit from this insight long term
• I can • tell my story and introduce a model• promote a relevant course at the PhD-school
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Management
Sales Marketing
Medicine
Communication
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Focus for this presentation
• Introduction & Goal
• Impact of scientific presentations!
•A model
•Examples & Hints
•Promotion !
• Summing up
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Presenting your findings
The conditions
• Complicated stuff
• One out of many topics
• Challenging audience
• Influence on resources and budgets
• Impact on own career
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Presenting your findings
Your way to an optimal presentation
•Refine the messages
•Make it simple to communicate
•Make it easy to understand
•Rehearse and train
• Increase your confidence
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The model
Communicative
Scientific
Technical
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A scientific element
•Choose contents
•Make your story
•Check relevance
• Stick to the messages
•Remove redundant stuff
•Avoid the details
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A communicative element
•Keep the story as simple as possible
•Make the story interesting
•Be true to the story line
•Keep focus on key elements
• ‘Let everything support you!’
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A technical element
•Prepare and prepare …
•Understand the signals
•Rehears alone and with peers
•Prepare for a safe landing
•Train the practical stuff
• Increase your own confidence
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Your optional gains
•Higher impact
•More effective influence
•Higher acknowledgement
•Change in self esteem
• Increased visibility
•Easier for yourself
• Lower stress infringement‘… not an easy catch!’
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Why is my presentation important?
•Paving way for next presentation
•Oral versus poster
•Plenum versus parallel session
•Nominations / Best presentation
•Proceedings / Summaries / Closing session
•Contacts / Agreements / Opportunities
Scientific, Communicative and Technical elements are key!
Focus for this presentation
• Introduction & Goal
• Impact of scientific presentations!
•A model
•Examples & Hints
•Promotion !
• Summing up
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Hints and advice
‘Tell your story!’
‘Let the slides support you!’
‘Keep the overview!’
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Hints and advice
‘Tell your story!’
‘Let the slides support you!’
‘Keep the overview!’
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Tell your Story
Make your story Prepare a short storyKey messagesConclusionsTake home messagesLeave behind
The importance of the StoryConsistent implementing the key elements
The story
Elements in the classical story telling
Start
Mid
End
Creating interestSetting the scene, the challenge, the hypothesis
How, what, plans, challenges, helpers, fear, experiences, fight, struggles, trouble, mistakes, success, new ideas, second thoughts, results, discussion, wider aspects …
End of journey, consequences, conclusions, next steps
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The story – An exampleBackgrounder: Atrial fibrillation
Standard of care: warfarinRequires monitoring (doctor, nurse, patient)Complex dose regimenMedium compliance
Opportunity for new kind of treatmentNew anticoagulantsOral treatment, once dailyHigh compliance
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Connell at al: RE-LY
•Dabigatran versus Warfarin
•Patients with Atrial Fibrillation
•NEJM
• Sept 2009
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The story – A classical one
•Current problems
•Optional future treatment
•Effective trial setup
•Many interesting results
•Discussion and theories
•Conclusion
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Opportunities
Current regimen is not optimal.Dabigatran is a new option.Is there room for at new treatment?Will dabigatran take over the entire treatment?
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Opportunities
Dabigatran 110 mg shows same effect as warfarin with less major hemorrages.Dabigatran 150 mg shows better effect than warfarinDabigatran 110 mg for most patients?Dabigatran 150 mg is superior to 110 mg?
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The story – in short
•Current treatment increases the risk of hemorrhage and is difficult to use.
•Dabigatran could be a new treatment option.
•A clinical trial with three arms did not reveal clear results.
•We discuss other aspects and trials and find dabigatran superior to warfarin.
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Exciting?
From dull to interesting
•Current problems
•Optional future treatment
•Effective trial setup
•Many interesting results
•Discussion and theories
•Conclusion
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•Room for a new entry?
•Challenging trial setup
•Difficult interpretation
•New hypothesis
•Claims
The story – in short
•Current treatment increases the risk of hemorrhage and is difficult to use.
•Dabigatran could be a new treatment option.
•A clinical trial with three arms did not reveal clear results.
•We discuss other aspects and trials and find dabigatran superior to warfarin.
The almost full story
• Current treatment increases the risk of hemorrhage and is difficult to use. • Dabigatran has another profile, requires no monitoring and
could be a new treatment option. Will dabigatran be drug of choice from now on?• To speed up registration of dabigatran, we chose a clinical
trial with three arms. Unfortunately this trial did not reveal clear overall results. • For academic reasons we discuss other aspects and trials
and find dabigatran superior to warfarin.
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… a publication in Lancet will contain more relevant information.
Wallentin
•Outcomes of RE-LY in relation to the centre’s mean TTR in the warfarin population
• Lancet
• Sept 2010
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Wallentin – The story
•Aim and setup
•Analysis
•Results
•Discussion
•Conclusion
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Most advantages of dabigatranin centres with poor INR control
The full story
• Current treatment increases the risk of hemorrhage and is difficult to use. • Dabigatran has another profile, requires no monitoring and
could be a new treatment option. Will dabigatran be drug of choice from now on?• To speed up registration of dabigatran, we chose a clinical
trial with three arms. Unfortunately this trial did not reveal clear overall results. • For academic reasons we discuss other aspects and trials
and find dabigatran superior to warfarin.• For patients in sub-optimal treatment, dabigatran may
have advantages, also if compliance can be improved. 30
The interesting story
• Current treatment increases the risk of hemorrhage and is difficult to use. • Dabigatran has another profile, requires no monitoring and
could be a new treatment option. Will dabigatran be drug of choice from now on?• To speed up registration of dabigatran, we chose a clinical
trial with three arms. Unfortunately this trial did not reveal clear overall results.• For academic reasons we discuss other aspects and trials
and find dabigatran superior to warfarin.• For patients in sub-optimal treatment, dabigatran may
have advantages, also if compliance can be improved. 31
The interesting short version
Is dabigatran the future drug of choice?
Unfortunately RE-LY did not show this?
AF-patients in sub-optimal treatment
may benefit from treatment with dabigatran!
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Reactions…
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Impact?
Guidance?
Interest?
Conclusions about The Story
•Massage your message!
•Tell the interesting story from start!
•Use key messages consistently
•Remember take-home-messages
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Hints and advice
‘Tell your story!’
‘Let the slides support you!’
‘Keep the overview!’
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Let the slides support you
Select message(s)Use bulletsUse elements if relevantUse animation if relevantDon’t overdo it!
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Pre-Exposure Prophylaxis
PrEP is short for Pre-Exposure Prophylaxis.
It is a new HIV prevention method in which people who do not have HIV take a daily pill to reduce their risk of becoming infected.
When used consistently, PrEP has been shown to reduce the risk of HIV infection among adult men and women at very high risk for HIV infection through sex or injecting drug use.
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Pre-exposure
PrEP is short for Pre-Exposure Prophylaxis. It is a new HIV prevention method in which people who do not have HIV take a daily pill to reduce their risk of becoming infected. When used consistently, PrEP has been shown to reduce
the risk of HIV infection among adult men and women at very high risk
for HIV infection through sex or injecting drug use.
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Pre-Exposure Prophylaxis
PrEP is short for Pre-Exposure Prophylaxis.
It is a new HIV prevention method in which people who do not have HIV take a daily pill to reduce their risk of becoming infected.
When used consistently, PrEP has been shown to reduce the risk of HIV infection among adult men and women at very high risk for HIV infection through sex or injecting drug use.
40
Pre-Exposure Prophylaxis
PrEP is short for Pre-Exposure Prophylaxis.
It is a new HIV prevention method in which people who do not have HIV take a daily pill to reduce their risk of becoming infected.
When used consistently, PrEP has been shown to reduce the risk of HIV infection among adult men and women at very high risk for HIV infection through sex or injecting drug use.
41
Pre-Exposure Prophylaxis
PrEP is short for Pre-Exposure Prophylaxis.
It is a new HIV prevention method in which people who do not have HIV take a daily pill to reduce their risk of becoming infected.
When used consistently, PrEP has been shown to reduce the risk of HIV infection among adult men and women at very high risk for HIV infection through sex or injecting drug use.
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Society and culture
• AIDS stigma exists around the world in a variety of ways.
• Ostracism, rejection, discrimination and avoidance of HIV infected people.
• Compulsory HIV testing without prior consent or protection of confidentiality.
• Violence against HIV infected individuals or people who are perceived to be infected with HIV.
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Society and culture
AIDS stigma exists around the world in a variety of ways, including ostracism, rejection, discrimination and avoidance of
HIV infected people; compulsory HIV testing without prior consent or protection of confidentiality; violence against
HIV infected individuals or people who are perceived to be infected with HIV.
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Society and culture
• AIDS stigma exists around the world in a variety of ways.
• Ostracism, rejection, discrimination and avoidance of HIV infected people.
• Compulsory HIV testing without prior consent or protection of confidentiality.
• Violence against HIV infected individuals or people who are perceived to be infected with HIV.
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Genes Coding Structural Proteins: gag
• The gag gene – core and shell expressed as p55 – (p18, p17) cleaved as p15, p18 and p24 make up as viral core and shell
• p24 seen during early stages reappearance in the late stages exacerbation of disease
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Genes Coding Structural Proteins: gag
• The gag gene – core and shell expressed as p55 – (p18, p17) cleaved as p15, p18 and p24 make up as viral core and shell
• p24 seen during early stages reappearance in the late stages exacerbation of disease
49
Genes Coding Structural Proteins: gag
The gag gene – core and shell expressed as p55 – (p18, p17) cleaved as p15, p18 and p24 make up as viral core and shell
p24 seen during early stages reappearance in the late stages exacerbation of disease
50
Genes Coding Structural Proteins: gag
• The gag gene – core and shell expressed as p55 – (p18, p17) cleaved as p15, p18 and p24 make up as viral core and shell
• p24 seen during early stages reappearance in the late stages exacerbation of disease
51
Genes Coding Structural Proteins: gag
• The gag gene – core and shell expressed as p55 – (p18, p17) cleaved as p15, p18 and p24 make up as viral core and shell
• p24 seen during early stages reappearance in the late stages exacerbation of disease
52
Conclusions about the slides
• Let the slides support you
•Remove the difficult parts
•Adjust the slides until they ‘help you out’
•Use extra slides or animations as a help
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Hints and advice
‘Tell your story!’
‘Let the slides support you!’
‘Keep the overview!’
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Keep the overview!
Back to your storyUse of print out with timingPrepare short cutsPrepare standard phrasesUse PageNumber + EnterAsk questions to win timeUse the chairman, your colleagues
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This was a very relevant discussion. The next example is of a more political character: Social rejection.
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15
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This was a very relevant discussion. The next example is of a more political character: Social rejection.
The second example is a story about gag 17 and 24 is supported with an illustration. Or is it…?
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12
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Conclusions about the overview
•Know your presentation
• Learn start up points by heart
• Find and mark short cuts
•Use the audience
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Focus for this presentation
• Introduction & Goal
• Impact of scientific presentations!
•A model
•Examples & Hints
•Time for promotion !
• Summing up
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Do you want to learn more … ?
1
2
3
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Course:
Presentation of medical results
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Training course is running over three weeks
Use of peer’s / teacher’s feedback
Focus on implementation
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Objectives of the course
•Define the goal of the presentation
•Describe situation and expectations from the audience
•Analyze and prioritize among optional contents
•Prepare story line and develop presentation
•Rehearse and adjust contents and performance
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Timeline
Next course: 5/5 19/5
Identify personal goals. Select homework presentation Prepare mini-presentation
Theory, intro to the TriadeMini-presentations with practical hands-on experience.
Implementation of learnings. Personal training session with feedback and input to contents.
Homework presentation. Triade check points.Shared learnings.
Preparation Day 1 Homework + sparring Day 2
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Focus for this presentation
• Introduction & Goal
• Impact of scientific presentations!
•A model
•Examples & Hints
•Promotion !
• Summing up
64
Summing up
• The impact!
• The model• Scientific• Communicative• Technical
• Examples• The Interesting Story• The Supporting slides• The Full Overview
• A promotion !65
Thank you for your time!Jesper Møller
