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PEEL AND SEED OF EUPHORIA LONGAN’S POTENSION AS TOPICAL GEL FOR INCREASING HEALING PROCESS AFTER TOOTH EXTRACTION Written by: Susilawati 1 , Mohammad Khafid 1 , Tiarisna Hidayatun Nisa 1 1 Student of Dentistry Faculty, Airlangga University Surabaya Abstract Background: Dental extractions is one of the common procedure in dentistry. Following extraction of a tooth, a blood clot forms in the socket within an hour. The raw of open wound overlying the dental socket takes about one week to heal. Thereafter, the socket will gradually filled in with soft gum tissue over a period of about one to two months. Final closure of the socket with bony remodelling can take six months or more. Post extraction’s scar can’t be back to normal optimally. Eleven billion patient in a day feel uncomfort such as pain, oedema, and bruised. To overcome this case, some herbal medicine can be used for healing in post extraction tooth. One of an effective herbal medicine is Euphoria longan, a popular plant mostly found in Indonesia. Usually, people just use longan pulp wheareas the peel and seed that weight 17% from whole fruit was thrown away. Based on some research, longan peel and seed consist of corilagin, galic acid, and ellagic acid which have antiplasmodial, antimicroba, antioxidant, antiinflamation effect and contain the compound to prevent cancer. Discussion Chemical compound of Euphoria longan peel and seed can increase healing process. Anti microbial activity can prevent secunder infection that usually make bad infulence in healing process. Antioxidant activity will blocked NO (Nitrite Oxide) production in tissue damage process. Antiinflamation activity will decrease exudate of acute inflamation and stimulated limfosit T and macrophage. Conclusion peel and seed of Euphoria longan can increase healing process in dental post extraction. Keywords: peel and seed of Euphoria longan, healing process, dental extraction

Potensi kulit dan biji kelengkeng sebagai gel topikal untuk mempercepat penyembuhan luka paskaekstraksi gigi

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Page 1: Potensi kulit dan biji kelengkeng sebagai gel topikal untuk mempercepat penyembuhan luka paskaekstraksi gigi

PEEL AND SEED OF EUPHORIA LONGAN’S POTENSION AS

TOPICAL GEL FOR INCREASING HEALING PROCESS

AFTER TOOTH EXTRACTION

Written by:

Susilawati1, Mohammad Khafid

1, Tiarisna Hidayatun Nisa

1

1Student of Dentistry Faculty, Airlangga University Surabaya

Abstract

Background: Dental extractions is one of the common procedure in dentistry.

Following extraction of a tooth, a blood clot forms in the socket within an hour.

The raw of open wound overlying the dental socket takes about one week to heal.

Thereafter, the socket will gradually filled in with soft gum tissue over a period of

about one to two months. Final closure of the socket with bony remodelling can

take six months or more. Post extraction’s scar can’t be back to normal optimally.

Eleven billion patient in a day feel uncomfort such as pain, oedema, and bruised.

To overcome this case, some herbal medicine can be used for healing in post

extraction tooth. One of an effective herbal medicine is Euphoria longan, a

popular plant mostly found in Indonesia. Usually, people just use longan pulp

wheareas the peel and seed that weight 17% from whole fruit was thrown away.

Based on some research, longan peel and seed consist of corilagin, galic acid, and

ellagic acid which have antiplasmodial, antimicroba, antioxidant, antiinflamation

effect and contain the compound to prevent cancer. Discussion Chemical

compound of Euphoria longan peel and seed can increase healing process. Anti

microbial activity can prevent secunder infection that usually make bad infulence

in healing process. Antioxidant activity will blocked NO (Nitrite Oxide)

production in tissue damage process. Antiinflamation activity will decrease

exudate of acute inflamation and stimulated limfosit T and macrophage.

Conclusion peel and seed of Euphoria longan can increase healing process in

dental post extraction.

Keywords: peel and seed of Euphoria longan, healing process, dental extraction

Page 2: Potensi kulit dan biji kelengkeng sebagai gel topikal untuk mempercepat penyembuhan luka paskaekstraksi gigi

POTENSI KULIT DAN BIJI KELENGKENG (Euphoria longan) SEBAGAI

GEL TOPIKAL UNTUK MEMPERCEPAT PENYEMBUHAN LUKA

PASKA EKSTRAKSI GIGI

Ditulis Oleh:

Susilawati1, Mohammad Khafid

1, Tiarisna Hidayatun Nisa

1

1Mahasiswa Universitas Airlangga Surabaya

Abstrak

Latar Belakang : Ekstraksi gigi merupakan prosedur yang paling sering

dilakukan di kedokteran gigi. Luka ekstraksi gigi diperkirakan 1-11,5%

mengalami penyembuhan yang tidak optimal.

Friedman (2007) berpendapat

bahwa terdapat 11 juta pasien per hari yang mengalami ketidaknyamanan seperti

nyeri, pembengkakan, dan memar pasca operasi pencabutan gigi. Untuk

mengatasi hal itu, tanaman obat dapat digunakan untuk mempercepat proses

penyembuhan luka. Tanaman kelengkeng (Euphoria longan) merupakan tanaman

yang banyak ditemukan di Indonesia. Pada umumnya, masyarakat hanya

memanfaatkan daging buah kelengkeng sementara kulit dan biji kelengkeng

sebesar 17% dari berat keseluruhan buah hanya berakhir sebagai limbah.

Berdasarkan penelitian, kulit dan biji kelengkeng mengandung senyawa corilagin,

asam galat dan asam ellagat yang berfungsi sebagai antiplasmodial, antimikroba,

antioksidan, antiinflamasi dan senyawa pencegah kanker. Pembahasan : Sifat

antibakterial, antioksidan dan antiinflamasi pada kulit dan biji kelengkeng dapat

mempercepat proses penyembuhan luka. Aktivitas antimikroba mencegah

terjadinya infeksi sekunder pada daerah luka yang berpengaruh pada proses

penyembuhan. Aktivitas antioksidan akan menghambat produksi NO yang

berperan dalam terjadinya kerusakan jaringan. Sedangkan aktivitas antiinflamasi

akan mengurangi eksudat inflamasi akut dan menstimulasi aktivasi limfosit T dan

makrofag. Kesimpulan : Kulit dan biji kelengkeng dapat mempercepat proses

penyembuhan luka pasca ekstraksi gigi.

Kata Kunci: Luka ekstraksi gigi, Kulit dan biji kelengkeng, Antiinflamasi