Porcine Xenograft

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Porcine Heterografts

Types of Grafts

Heterografts: tissues transferred from one species to an unrelated species (xenografts / zoografts) Homografts: tissues transferred from one individual to another of the same species Autografts: tissue trasnferred from one area to another of the same individual

What is a Porcine Graft?

Xenograft From domestic pig sacrificed at 6 months of age Split-thickness skin 0.01 inches Preparation types: Antibiotic & bleach soak then electron beam Saturated with antiseptic solution or aldehyde starches

Biological AdvantagesAugment host immune defence & decreased bacterial count Re-establishes vapor barrier Decreased water & protein loss Increased rate of epithelialization No apparent immune response

Clinical AdvantagesAlleviates pain Protects cartilage, tendons, bone, nerves Facilitates motion and mobility Avoidance of harvesting STSG Inexpensive and unlimited supply

IndicationsLarge wounds Areas difficult to close Partial closure and granulation before delayed repair (avascular areas) Flap or graft contraindicated

ContraindicationsKnown sensitivity to porcine products History of multiple or serum allergies Wounds with large amounts of eschar

Types of Porcine Grafts

Perforated Promotes drainage Non-perforated Cartilage or bone areas Minimizes air exposure and deceases pain

Porcine XenograftEZ Derm Nonperforated Porcine Biosynthetic Wound Dressing

Porcine Heterografts in Dermatologic Surgery and Reconstruction Davis, DA and Arpey, CJ Dermatol Surg 2000;26:7680

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