PharmacoEconomics & Outcomes News 285 - 21 Oct 2000 Paediatric vaccination: the hidden costs The hidden costs of paediatric vaccination are substantial, report investigators from Kaiser Permanente, Oakland, California, and the Centers for Disease Control and Prevention, Atlanta, Georgia, US. The investigators performed a cross-sectional survey of 1657 caregivers of paediatric patients aged 1–8 months who received vaccines at Northern California Kaiser Permanente between April and June 1997. * ; † The results indicated that caregivers incur considerable psychological and economic costs when their children receive multiple injections during a single clinic visit or experience adverse effects due to vaccination. Multiple shots bring a cost . . . Caregivers reported that they would be willing to pay a median of $US25 (1997 values) to reduce the number of simultaneous injections that their charges would receive from 4 to 3, or from 3 to 2, while still providing the same level of disease protection. Caregivers said they would be willing to pay a median of $US50 to reduce the number of simultaneous injections from 2 to 1. If 4 injections had been due at a single clinic visit, 55% of caregivers indicated that they would have preferred < 4 injections to be given at the first visit, and for the remaining injections to be given at a follow-up visit. Each follow-up visit had an estimated work-loss cost of $US30. . . . as do adverse effects 73% of caregivers reported that their charges experienced ≥ 1 adverse event, mostly fussiness (46%), injection-site pain (35%) and fever (31%). Parents reported that they would have been willing to pay a median of $US50 to avoid these symptoms. Furthermore, vaccination-related adverse effects incurred a total mean cost of $US7.70 per vaccination visit: $US2.91 in costs for clinic visits or telephone calls to advice nurses; $US4.05 in work-loss costs; and $US0.74 in direct nonmedical costs due to families requiring transportation, parking or extra babysitting. * Data were collected by telephone interview 2 weeks after paediatric vaccination. † The vaccines included: diphtheria, tetanus, pertussis and Haemophilus influenzae type b vaccine (1269 injections); hepatitis B virus vaccine (1172); pneumococcal conjugate vaccine (< 639); diphtheria, tetanus and acellular pertussis vaccine (388); Haemophilus influenzae type b vaccine (383); inactivated poliovirus vaccine (266); and measles, mumps and rubella vaccine (2). Lieu TA, et al. The hidden costs of infant vaccination. Vaccine 19: 33-41, 15 Aug 2000 800846225 1 PharmacoEconomics & Outcomes News 21 Oct 2000 No. 285 1173-5503/10/0285-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Paediatric vaccination: the hidden costs

Download PDF Report

Upload
masatoshi
View
217
Download
2

Embed Size (px)

Citation preview

PharmacoEconomics & Outcomes News 285 - 21 Oct 2000

Paediatric vaccination: the hiddencosts

The hidden costs of paediatric vaccination aresubstantial, report investigators from KaiserPermanente, Oakland, California, and the Centers forDisease Control and Prevention, Atlanta, Georgia, US.

The investigators performed a cross-sectional surveyof 1657 caregivers of paediatric patients aged 1–8months who received vaccines at Northern CaliforniaKaiser Permanente between April and June 1997.*;† Theresults indicated that caregivers incur considerablepsychological and economic costs when their childrenreceive multiple injections during a single clinic visit orexperience adverse effects due to vaccination.

Multiple shots bring a cost . . .Caregivers reported that they would be willing to pay

a median of $US25 (1997 values) to reduce the numberof simultaneous injections that their charges wouldreceive from 4 to 3, or from 3 to 2, while still providingthe same level of disease protection. Caregivers saidthey would be willing to pay a median of $US50 toreduce the number of simultaneous injections from 2 to1.

If 4 injections had been due at a single clinic visit, 55%of caregivers indicated that they would have preferred <4 injections to be given at the first visit, and for theremaining injections to be given at a follow-up visit. Eachfollow-up visit had an estimated work-loss cost of$US30.

. . . as do adverse effects73% of caregivers reported that their charges

experienced ≥ 1 adverse event, mostly fussiness (46%),injection-site pain (35%) and fever (31%). Parentsreported that they would have been willing to pay amedian of $US50 to avoid these symptoms.Furthermore, vaccination-related adverse effectsincurred a total mean cost of $US7.70 per vaccinationvisit: $US2.91 in costs for clinic visits or telephone callsto advice nurses; $US4.05 in work-loss costs; and$US0.74 in direct nonmedical costs due to familiesrequiring transportation, parking or extra babysitting.* Data were collected by telephone interview 2 weeks after paediatricvaccination.† The vaccines included: diphtheria, tetanus, pertussis andHaemophilus influenzae type b vaccine (1269 injections); hepatitis Bvirus vaccine (1172); pneumococcal conjugate vaccine (< 639);diphtheria, tetanus and acellular pertussis vaccine (388); Haemophilusinfluenzae type b vaccine (383); inactivated poliovirus vaccine (266);and measles, mumps and rubella vaccine (2).

Lieu TA, et al. The hidden costs of infant vaccination. Vaccine 19: 33-41, 15 Aug2000 800846225