Communications affichdes/Posters 45s

P23

CORRELATION OF EEG, CEREBRAL MAPPING AND MAGNETIC

RESONANCE IN MULTIPLE SCLEROSIS PATIENTS.

D. Facchetti, M.Poloni ~ , R. Capra ~H~ , F. Mattioli, R.

Gasparotti ~ . Department of Medical Rehabilitation,

Centre Medico di Gussago, Fondazione Clinica del Lavoro.

~Pirst Neurological Clinic, University of Milan. ~Neuro-

logical Clinic, University of Brescia. ~Department of

Radiology, University of Brescia.

Sexteen patients with clinically definite multiple scle-

rosis were studied with traditional EEGs, cerebral mapping

and magnetic resonance imaging. The mean age of the

patients was 35.2 (range 19-60); 12 were female and 4

male. Signals, digitalized at a rate of 180 per second,

were selected and fast fourier tranformed. Spectral

parameter data were visualized to form cerebral maps. A

control group matched for age and sex and with no known

neurological disturbance underwent the same examination

(excluding MRI).

The visually evaluated EEG records revealed abnormalities

in a cases or 25% consisting of diffuse slowings (theta or

theta and delta) in 3 cases and focal slow activity in 3

cases (associated with diffuse slowings in 2). Minor

abnormalities such as flat records over the occipital

areas were seen in 4 cases and diffuse fast rhythmic

activity of high or low voltage associated with the other

patterns was observed in 4 cases. By mean of cerebral

mapping and statistic significance probability mapping a

significant increase in the theta and delta band total

power was demonstrated in 9 cases or 56.2%. A correlation

between these findings with MRI results, clinical patterns

arld physical disability as defined by Kurtzke was

ettempented.

We would thank Miss M. Teresa Battista for the valuable help and technical assistance.

P25 EEG AND BRAIN MAPPING IN EMBOLIZATION OF ARTERIO-

VENOUS MALFORMATION S. Anton, A. Yusta*, J. Brasa**, L. Nombela** and G. Bravo***, Services of Clinical Neurophysiolo- gy, *Neurology, **Neuroradiology and ***Neurosur- gory. Clinica Puerta de Hierro; San Martin de Porres, 4; Madrid 28035, Spain

EEG, brain mapping and the Amytal test were

employed in the continuous monitoring of patients

with intracerebral arteriovenous malformation

(AVM) who were to undergo endovascular treatment

via superselective catheterization of the lesion

pedicles. The process requires special techniques

and collaboration among a wide multidiscip~ine

team.

We studied 123 patients with intracerebral

AVM, 38 of whom were embolized and 23 of whom un-

derwent embolization plus surgery.

This study has led us to conclude that brain

mapping allows earlier and more precise detection

of ischemia than conventional EEG, and that these

two techniques together with meticulous clinical

examination increase the degree of safety of endo-

Vascular treatment.

P24

QUANTITATIVE EEG (qEEG) EVALUATION IN PATIENTS WITH SUBCORTI

CAL VASCULAR ENCEPHALOPATHY (SVE). CORRELATION WITH NEURORA

DIOLOGICALAND NEUROPSYCHOLOGICAL FINDINGS.

P. Novello, G. Ajmar, E. Canevari, L. Corsello, C. Finocchi,

and A. Primavera, Dept. of Neurology, University of Genoa,

Genoa-ITALY.

Fifteen patients with SVE (with or without a diagnosis of

dementia) were studied in relation to age, performance in

neuropsychologic tests (Mini-Mental State and its sub-tests

for orientation, registration, attention, recall,language),

neuroradiological findings (White Matter Low Attenuation,

small deep infarcts, cortical atrophy), and qEEG parameters

(Mean Frequency in the range 1-16 Hz and Percent Difference,

according to Chotas et al. 1979). Correlation analysis demon

strates a significant relationship between age and WMLA, bet

ween MMS examination and WMLA, small deep infarcts and PD

values in occipital derivation. There was no correlation bet

ween MMS examination and MF. Significant correlations have

also been showed between PD values and neuropaychological

performances for registration and language, while the MF va

lues showed significant relationship only with the language.

No correlations have been showed between neuroradiological

findings, on one hand, and neuropsychologic sub-tests and

qEEG parameters, on the other hand.

Our results demonstrate that the qEEG, particularly PD va

lues, has a good correlation with cognitive performances in

elderly patients with SVE, and so it gives valuable data for

the differentiation between normal and pathological aging.

P26 MULTIMODALITY EVOKED POTENTIALS AND EEG IN A CASE OF CHERRY RED SPOT MYOCLONUS SYNDROME.

LOUBOUTIN J.P. ; NOGUES B.; ELIE B. ; YHUEL X.

Clinisue NeurologiQue ~ Laboratoire d'Ex~lorations Fonctionnelles-CHR NANTES - CH de SAINT NAZAIRE - FRANCE

Giant SEPs and EEG alterations are well known in Progressive Myoclonus Epilepsy. However other EPs may be observed. We report such a neurophysiological study ~n one case of Cherry Red Spot Myoclonus Syndrome (CRSMS). Multimodality Evoked Potentials (SEPs, MEPs, VEPs, BAEPs Trigemina] EPs), Blinck Reflex, Nervous Conduction VeLocities (NCV), Sympathetic Skin Response (SSR), EEG were sequentially performed. Biochemical studies including sialyloligosacehar~des in urine and betagalaetosidase in serum assays were done. Giant SEPs and naro×ysmal EEG abnormalities were observe@. VEPs and BAEPs were also found to be abnormal in latency and amplitude. NCV, SSR were normal as well as MEPs. Beside classical giant SEPs and EEG features, Cherry Red Spot Myoclonus Syndrome may be associated with other neurophysiological abnormalities.