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Ozgur Tataroglu, PhD 35 Dustin st, Worcester, MA, 01604 Phone: 774 239 6018 E-mail: [email protected] Qualifications: PhD level scientist with 16 years of research experience in molecular biology, cellular biology, genetics and protein biochemistry in interdisciplinary topics such as fungal, insect and mammalian biology, animal behavior, psychobiology and high-throughput methods. Demonstrated leadership, supervisory and teamwork experience at every level from undergraduate student to postdoctoral scholar that includes project management, organizational skills, resource allocation and advanced training and mentoring to 10+ graduate and undergraduate level scientists and technicians across disciplines. Proven ability to set clear goals, meet deadlines, design and lead interdisciplinary research teams which successfully culminated in 10 peer-reviewed articles (7 first authored) in high profile journals (incl. Cell), with over 240 citations and multiple academic research excellence and funding awards. Excellent written and oral communication skills demonstrated by invited talks at academic institutions and conferences and highly-cited academic research and review papers. Extensive experience in plasmid and viral vector design, sequence-independent high- throughput cloning and mutagenesis, protein expression and purification, CRISPR/Cas9, lenti-viral and vector-based transfection and expression of gain-of-function or RNAi vectors in insect and mammalian cell cultures, generation of immortalized mammalian and insect cell lines, high throughput plate-based cell and drug screens. US work authorization and green card. Publications: Tataroglu O, Zhao X, Busza A, Ling J, O'Neill JS and Emery P. (2015) Calcium and SOL protease mediate temperature resetting of circadian clocks. (Cell, Vol.163, Issue 5,1214- 1224). Tataroglu O, Emery P. (2015) Molecular ticks of the Drosophila circadian clock. (Curr. Opinion in Insect Sci. DOI: 10.1016/j.cois.2015.01.002). Tataroglu O, Emery P. (2014) Studying circadian rhythms in Drosophila melanogaster. (Methods. Jun 15;68(1):140-50). Tataroglu O, Lauinger L, Sancar G, Jakob K, Brunner M, Diernfellner AC. (2012) Glycogen synthase kinase is a regulator of the circadian clock of Neurospora crassa. (J Biol Chem. Oct 26;287(44):36936-43). Tataroglu O, Schafmeier T. (2010). Of switches and hourglasses: regulation of subcellular traffic in circadian clocks by phosphorylation. (EMBO Rep. 11(12):927-35). Miranda-Anaya M., Mohawk J.A., Tataroglu O., Menaker M. (2009). Lithium and Genetic inhibition of GSK3β enhance the effect of Methamphetamine on circadian rhythms in the mouse. (Behav Pharmacol. 20(2):174-83).

Ozgur Tataroglu-Scientific resume

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Page 1: Ozgur Tataroglu-Scientific resume

Ozgur Tataroglu, PhD

35 Dustin st, Worcester, MA, 01604 Phone: 774 239 6018 E-mail: [email protected]

Qualifications:

PhD level scientist with 16 years of research experience in molecular biology, cellular

biology, genetics and protein biochemistry in interdisciplinary topics such as fungal, insect

and mammalian biology, animal behavior, psychobiology and high-throughput methods.

Demonstrated leadership, supervisory and teamwork experience at every level from

undergraduate student to postdoctoral scholar that includes project management,

organizational skills, resource allocation and advanced training and mentoring to 10+

graduate and undergraduate level scientists and technicians across disciplines.

Proven ability to set clear goals, meet deadlines, design and lead interdisciplinary research

teams which successfully culminated in 10 peer-reviewed articles (7 first authored) in high

profile journals (incl. Cell), with over 240 citations and multiple academic research excellence

and funding awards.

Excellent written and oral communication skills demonstrated by invited talks at academic

institutions and conferences and highly-cited academic research and review papers.

Extensive experience in plasmid and viral vector design, sequence-independent high-

throughput cloning and mutagenesis, protein expression and purification, CRISPR/Cas9,

lenti-viral and vector-based transfection and expression of gain-of-function or RNAi vectors in

insect and mammalian cell cultures, generation of immortalized mammalian and insect cell

lines, high throughput plate-based cell and drug screens.

US work authorization and green card.

Publications:

Tataroglu O, Zhao X, Busza A, Ling J, O'Neill JS and Emery P. (2015) Calcium and SOL protease mediate temperature resetting of circadian clocks. (Cell, Vol.163, Issue 5,1214- 1224).

Tataroglu O, Emery P. (2015) Molecular ticks of the Drosophila circadian clock. (Curr. Opinion in Insect Sci. DOI: 10.1016/j.cois.2015.01.002).

Tataroglu O, Emery P. (2014) Studying circadian rhythms in Drosophila melanogaster. (Methods. Jun 15;68(1):140-50).

Tataroglu O, Lauinger L, Sancar G, Jakob K, Brunner M, Diernfellner AC. (2012) Glycogen synthase kinase is a regulator of the circadian clock of Neurospora crassa. (J Biol Chem. Oct 26;287(44):36936-43).

Tataroglu O, Schafmeier T. (2010). Of switches and hourglasses: regulation of subcellular traffic in circadian clocks by phosphorylation. (EMBO Rep. 11(12):927-35).

Miranda-Anaya M., Mohawk J.A., Tataroglu O., Menaker M. (2009). Lithium and Genetic inhibition of GSK3β enhance the effect of Methamphetamine on circadian rhythms in the mouse. (Behav Pharmacol. 20(2):174-83).

Page 2: Ozgur Tataroglu-Scientific resume

Querfurth C, Diernfellner A, Heise F, Lauinger L, Neiss A, Tataroglu O, Brunner M, Schafmeier T. (2007). Posttranslational Regulation of Neurospora Circadian Clock by CK1a-dependent Phosphorylation. (Cold Spring Harb Symp Quant Biol. 72:177-83, 2007).

Tataroglu O., Davidson A., Menaker M. (2006). The methamphetamine-sensitive circadian oscillator (MASCO) in mice. (Journal of Biological Rhythms Jun;21(3):185-94).

Davidson A., Tataroglu O., Menaker M. (2005). Circadian effects of timed meals (and other rewards). (Methods in Enzymology 393:509-23).

Tataroglu O., Aksoy A., Yilmaz A., Canbeyli R. (2004). Effects of lesioning the suprachiasmatic nuclei on behavioral despair in rats. (Brain Research 1001(1-2):118-24).

Honors and Awards:

2016 Invited Speaker at Dept. of Pharmacology, University of Cambridge. 2016 Invited Speaker at Division of Cell biology, Medical Research Council (MRC). 2016 Research Excellence Award and Invited Speaker at Society for Research on

Biological Rhythms (SRBR) annual meeting 2015 Invited Speaker, hot-topics oral presentation and registration and travel awards

for Gordon Research Conference on Chronobiology. 2014 Research Excellence Award and Invited Speaker at Society for Research on

Biological Rhythms (SRBR) annual meeting. 2013 Invited Speaker and travel award from Department of Biology, University of

Virginia. 2013 Poster award at Gordon Research Conference on Chronobiology 2013 Invited Speaker and travel award from Dept. of Biology, University of Virginia. 2008-2011 PhD fellowship, Cell Networks Excellence Cluster Program, Germany (€15000

salary plus €5000 for consumables for three years). 2003-2006 Graduate fellowship (stipend) from Department of Biology for teaching biology

courses. 1997 Undergraduate fellowship for ranking in top 0.02% (287th) and 0.1% (1484th) in

the first and second stages of the Turkish nationwide university entering exam out of 1.3 Million.

Professional and Research Experience:

Post-doctoral Fellow, Uni. of Massachusetts Medical School, Worcester,MA 2011-Present

Designed and initiated interdisciplinary research projects and established international

collaborations that resulted in successful discovery of the molecular mechanism of how

temperature resets the biological clock through calcium-dependent proteases. (Cell,

Vol.163, Issue 5, 2015).

Developed a novel assay for live imaging of mammalian and Drosophila cell cultures

using high-throughput luciferase recording and performed protease inhibitor screens.

Mentored 5 PhD students and technicians on various projects.

Successfully negotiated acquisition of expensive laboratory equipment with significant

discounts.

Page 3: Ozgur Tataroglu-Scientific resume

Ph.D Researcher, University of Heidelberg, Germany 2006-2011

Discovered a novel role for Glycogen Synthase Kinase in temperature compensation of

biological clocks and its phosphorylation targets on core biological clock proteins in the

filamenteous fungi Neurospora Crassa. (J Biol Chem. Oct 26, 2012)

Developed a novel kinase assay for phosphorylation of proteins in complex cell lysates.

Supervised multiple students and technicians and taught biology courses.

Education:

Ph.D. in Molecular Biology and Biochemistry, University of Heidelberg, Germany, 2011.

M.S. in Biology, University of Virginia, Charlottesville, VA, USA, 2006.

B.S. in Molecular Biology and Genetics, Bogazici University, İstanbul, Turkey, 2002.