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Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 1: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 2: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 3: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 4: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 5: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 6: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 7: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 8: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 9: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 10: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 11: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 12: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 13: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

7.4335.0676.3672097117BSC

9.3006.2007.40058134192Optune

CL95%SurvivalCensoredEventSubjects

Median

192 165 131 99 77 63 52

117 98 72 57 41 29 23

Optune

BSC

0 2 4 6 8 10 12

Overall Survival (Months)

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

Fra

cti

on

0 2 4 6 8 10 12

Overall Survival (Months)

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

Fra

cti

on

BSC

Optune

Treatment

+ Censored

•

•

•

•

Page 14: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 15: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 16: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 17: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 18: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 19: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 20: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 21: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 22: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

Kaplan-Meier OS Kaplan-Meier OS

Page 23: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 24: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 25: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 26: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 27: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 28: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 29: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 30: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 31: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 32: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 33: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 34: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 35: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 36: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 37: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 38: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 39: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

+ + + + + + + + + + + + + + +

- - - - - - - - - - - - - - -

+

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-

Page 40: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30
Page 41: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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Page 42: Novocure (NVCR) overview · 01+1sotype Control+aPD-1 TTFields+Isotype TTFields+aPD-1 150 100 50 0.01 paclitaxel —e— Paclitaxel + TTFieIds 10 Paclitaxel (nM) 100 90 30

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