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NGIC and BINAsia Jong Bhak NGIC KRIBB Korea

NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

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Page 1: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

NGIC and BINAsia

Jong Bhak

NGICKRIBBKorea

Page 2: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Acknowledgment

• APCTT• Biotec• Participants from Asian Countries• Organizing staff• MOSTfor support

Page 3: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

NGIC ChronicleNGIC Chronicle NGIC ChronicleNGIC Chronicle

2001. 04 : National Genome Information Center Proposed 2001. 07 : Detailed Establishment plan 2001. 10 : NGIC Launched 2003. 08 : Designated focal point for research data deposition 2004. 01 : Initiation of BioInformation Portal Service 2005. 03 : Data analysis system launched 2005. 08 : National BioInformation Center Proposed 2005. 12 : Detailed Establishment plan 2006. 02 : (Konbic) Korea National BioInformation Center 2006. 02 : (Konbic) Korea National BioInformation Center to be launchedto be launched

2001. 04 : National Genome Information Center Proposed 2001. 07 : Detailed Establishment plan 2001. 10 : NGIC Launched 2003. 08 : Designated focal point for research data deposition 2004. 01 : Initiation of BioInformation Portal Service 2005. 03 : Data analysis system launched 2005. 08 : National BioInformation Center Proposed 2005. 12 : Detailed Establishment plan 2006. 02 : (Konbic) Korea National BioInformation Center 2006. 02 : (Konbic) Korea National BioInformation Center to be launchedto be launched

NGIC HistoryNGIC HistoryNGIC HistoryNGIC History

Page 4: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

20032003 20042004 20052005 20062006

3333 명명4141 명명

5555 명명

연구비연구비

3,754

연구비단위 : 백만원

인원인원

Xeon LinuxXeon Linuxclustercluster

Sun serverSun server

StorageStorage

Origin3400Origin3400

PCPC 급 서버 급 서버 77 대대

Xeon LinuxXeon Linuxclustercluster

Sun serverSun server

StorageStorage

Opteron LinuxOpteron Linuxclustercluster

PCPC 급 서버 급 서버 1515 대대

Compaq serverCompaq server

1,997

Sun serverSun server

Origin3400Origin3400

PCPC 급 서버 급 서버 33 대대

Opteron ClusterOpteron Cluster 급 급 22 대 도입예정대 도입예정

PCPC 용 서버 용 서버 2020 대 운영대 운영

장비운영현황장비운영현황

Xeon LinuxXeon Linuxclustercluster

Sun serverSun server

StorageStorage

Opteron LinuxOpteron Linuxclustercluster

약 약 4,000 4,000 이상이상

3,504

약 약 6060 명명

NGIC presentNGIC present NGIC presentNGIC present

Page 5: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

KISTIKISTIKISTIKISTI

NGICNGICProteomicsProteomicsFrontierFrontier

ProteomicsProteomicsFrontierFrontier

HumanHumanGenomeGenomeFrontierFrontier

HumanHumanGenomeGenomeFrontierFrontier

MicrobialMicrobialGenomesGenomes

MicrobialMicrobialGenomesGenomes

KNIHKNIHKNIHKNIH

PlantPlantResourceResourceFrontierFrontier

PlantPlantResourceResourceFrontierFrontier

AgricultureAgricultureResearchResearchCentersCenters

AgricultureAgricultureResearchResearchCentersCenters

CattleCattleResearchResearchCentersCenters

CattleCattleResearchResearchCentersCenters

CropCropPlantPlant

FrontierFrontier

CropCropPlantPlant

FrontierFrontier

ETRIETRIETRIETRI

Large-Large-scalescaleDataDataGRIDGRID

ApplicationApplicationGRIDGRID

Operation network of NGIC

Page 6: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Genome Transcript Interactome FunctomeProteome Textome

Sequence

Structure

Expression

Pathway

Regulation

Network

Info TypeInfo TypeInfo TypeInfo Type

OmeOmeOmeOme

file

분석Pipeline

BioEngine DB

분석

BioDiversityMaterials Bank

자원

자원자원

BioBioResourceResource

2ndary Info2ndary Info2ndary Info2ndary Info 2ndary DB2ndary DB2ndary DB2ndary DB

BioBioMatrixMatrix

BioBioMatrixMatrix

Page 7: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Automatic BioInformation Pipeline Processing System

BioBioEngineEngine

IEAIEA

……..

HapMapHapMap

FESDFESD

PEIORFPEIORF

SNPSNP

CompCompGenomeGenome

BioPortalBioPortalBioPortalBioPortal

BioWikiBioWikiBioWikiBioWiki

진핵진핵유전체유전체

SiRNASiRNA

TF TF ExplorerExplorer

ActiveActivePromoterPromoter

RepeatomeRepeatome

GS2PATHGS2PATH

SIGPSIGP

BiozineBiozineBiozineBiozine

BioBioJournalJournal

BioBioJournalJournal

KUGIKUGI

SAGEDSAGED

NormPipeNormPipe

ArrayPortArrayPort

. . .. . .

Gene setGene setAnalyzeAnalyze

……

PSIMAPPSIMAP

……

PDSPDS

LoCalodomLoCalodom

StrokeStroke

TextomeTextome

Page 8: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

BioEngineBioEngine

ProteinProteinStructureStructure

ProteinProteinInteractionInteraction

GeneGeneRegulationRegulation

CancerCancerMicroarrayMicroarray

ChemicalChemicalGenomicsGenomics

siRNAsiRNABiomarkerBiomarker

SOLSOL

StrokeStroke

SNPSNP

ChimpanzeeChimpanzee

Biological DB Bioinformatic Tool BioPipeline 2ndary DBs Inhouse Bio Tool

Page 9: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

BinAsia as I see

• 1st stage: Biotechnology Introduction Network for Asia

• 2nd stage: Bio Information Net for Asia– Information Infrastructure– Information experts and staff– IT hardware infra– Virtual network interfaced with web.– Regular meetings by focal nodes and

focal node technicians

Page 10: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Practicals of BinAsia

• Establishment of working BioInformation Net• BioTechnology List for local nodes

– Agricultural BT• Biofertilizer, BioIndicator, Bioremediation• Biopesticides Biogas

– Commercialization of local knowledge– Training program in BioInformation Handling– Language issues Inglish ?

Page 11: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Todos– Establishing working National nodes for BinAsia– Establishing working a central information node– Integrated BioInfo DBs for local nodes– Basic information gathering by local and central node– Value-added information generation & dissemination– Analysis of Asian BT and BioInfoTech– Next meeting in Thailand?– Adjusting BINAsia funding and operation.– License issues http://biolicense.org/

Page 12: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Basic Info. Gathering

• Traditional knowledge in BT• Statistics on BT (industry and schools)• Bit BT projects

– Shrimp genome– Casava genome project

• Translating local language to English

Page 13: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Future

• Asian Biotechnology Information Network Virtual Regional Center

• In workin with other Asian BioInformation Centers– AMBL– eIMBL– Counterpart to EBI

• BT info. network for AU (Asian Union?)

Page 14: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Virtual Bioinformatics Center

•http://vbio.org/

Page 15: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

CJK bioinformatics Training course

• 5th CJK bioinformatics training course• Expansion of Training and Teaching program

– http://biomoodle.net/

Page 16: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

Proposed Role of NGIC for BINasia

• NGIC collects biotechnology DBs, information servers, tools and education materials

• NGIC serves a fast website for managing the above function.

• NGIC mirrors binasia.net site for backup.• NGIC represents Korean node of BINasia• NGIC supports BINasia meetings and admini

stration

Page 17: NGIC and BINAsia Jong Bhak NGIC KRIBB Korea. Acknowledgment APCTT Biotec Participants from Asian Countries Organizing staff MOSTfor support

ASEAN and NGIC

• ASEAN + Korea bioinformatics network• From year 2007, NGIC is likely to get more f

unding for international project such as BINAsia.