Neuroscience 1 (CNS) - كلية الطب theory exam .. EHSAN 2014 6 Q41. All of the followings are…

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  • CNS theory exam .. EHSAN 2014

    0

    Neuroscience 1 (CNS)

    EHSAN 2014

  • CNS theory exam .. EHSAN 2014

    1

    ANATOMY _______________________________________________________________________________________

    Q1. One of the following statements is correct:

    Blood brain barrier is not present in circumventricular organs

    Q2. . One of the following statements is correct:

    tanycytes detect hormonal concentrations in CSF

    Q3. The discriminative touch from the upper limbs are carried by:

    Cuneate tract

    Q4. Pain and temperature is carried by:

    Lateral spinothalamic tract.

    Q5. Postural movements of the head in response to visual stimuli are mediated by:

    Tectospinal tract

    Q6. The fibers that arise from the gracile and cuneate nuclei and cross the medline

    are called:

    Internal arcuate fibers.

    Q7. Paralysis of the right lower quadrant of the face is most probably caused by

    lesion in:

    Left internal capsule

    Q8. A sign of lower motor neuron injury:

    Loss of reflexes

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    LMN lesion accompanied mostly with muscle paralysis(flaccid Note>>

    paralysis) , fibrillation ,, hypotonia,, and hyporeflexia. This is contrast to

    UMN lesion that accompanied by severe hypertonia

    Q9. Broca's area is connected to wernicke's area by:

    Long association fibers

    Q10. The structure located between corpus callosum and fornix is called:

    Septum pellucidum

    Q11. One of the following statements is correct about the blood supply of the brain:

    Internal cerebral veins are united just inferior to splenium of corpus callosum

    Q12. Posterior inferior cerebellar artery arises from:

    Vertebral artery

    Q13. The pyramid of the medulla is supplied by:

    The anterior spinal artery

    Q14. Denticulate ligament is an extention of:

    Pia and arachnoid matters

    Q15. Lumbar enlargement is present in:

    L2-S3

    Q16. Which of the following is present in all segments of the spinal cord?

    Medial motor group

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    3

    Q17. Villi that absorb the CSF Are part of:

    The dura matter

    Q18. Located between the external and extreme capsules is the:

    Claustrum

    Q19. The layer # 4 of the cerebral cortex is the:.

    Internal granular layer of the cerebral cortex.

    Q20. The primary taste cortex is part of the

    Parietal

    Q21. The internal capsule continues downward as:

    Crus cerebri Q22. Brodmann area 43 is supplied by the:

    Middle cerebral artery

    Q23. The cerebrospinal fluid (CSF) is formed by the:

    Choroid plexuses.

    Q24. The only part of the ventricular system connected to the subarachnoid space is:

    Fourth ventricle

    Q25. basal ganglia arise from:

    neural tube

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    Q26. One of the following is a feature of spina bifida occulta:

    Vertebral canal remains open posteriorly

    Q27. Which of the following is not a clinical manifestation of Weber's Syndrome:

    Ipsilateral paralysis of lower part of the face

    Weber syndrome characterized by the presence of an ipsilateral oculomotor Note >>

    nerve palsy . contralateral hemiparesis and typical upper motor neuron findings.

    Difficulty with Contralateral lower facial muscles and hypoglossal nerve functions.

    Q28. Which cranial nerve nucleus is located in the rostral part of Pons?

    Trigeminal

    Q29. One of the following statements is correct:

    The pontine nuclei are located in the anterior part of the pons

    Stellate cells are located in: .30Q

    The outer part of the molecular layer of the cerebellar cortex

    Q31. Which intracerebellar nucleus is largest in size?

    Dentate nucleus

    Q32. The neostriatum of basal nuclei is formed by:

    Caudate and putamen

    Q33. The extreme capsule separates which parts of the grey matter?

    Insula and claustrum.

    Q34. Parkinson's disease is a clinical condition that happens due to:

  • CNS theory exam .. EHSAN 2014

    5

    Damage to substantia nigra

    PHARMACOLOGY

    Q35. Which of the following is NOT an expected action of chlorpromazine?

    Nausea and vomiting

    the most appropriate side effect of it is weight gain , sedation , acute movement Note>>

    disorder , parkinsonism , and decrease blood supply with dizziness.

    Q36. Haloperidol as a butyrophenone derivative:

    Is likely to be complicated by extrapyramidal symptoms.

    Q37. The antidepressant drug "fluoxetine":

    Has a relatively long duration of action

    Q38. Therapeutic uses of the tricyclic antidepressant drugs include all the following,

    EXCEPT:

    Arrhythmia

    The TCAs are used primarily in the clinical treatment of mood disordersNote >>

    Q39. General therapeutic principles in treatment with antiepileptic drugs (AEDs)

    include:

    Therapeutic drug monitoring is very useful in AED therapy

    Q40. Phenytoin is characterized by:

    Zero order kinetics metabolism with in therapeutic concentration.

  • CNS theory exam .. EHSAN 2014

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    Q41. All of the followings are therapeutic uses of the benzodiazepines,

    EXCEPT:

    Ethanol and barbiturate over dose

    Q42. Zolpidem:

    Has a rapid onset hypnotic effect.

    prescription medication that used for tt of insomnia and some brain its a NOTE>>

    disorder . It is a short-acting nonbenzodiazepine hypnotic that potentiates GABA, an

    inhibitory neurotransmitter, by binding to GABAA receptors at the same location as

    benzodiazepines.[4] It works quickly, and has a short half-life of two to three hours.

    Q43. Bromocriptine is :

    A dopamine receptor agonist

    and various serotonin , is a potent agonist at dopamine D2 receptorsits NOTE>>

    receptors.

    Q44. The main reason of avoiding the combined administration of L-dopa and the

    non selective mono amine oxidase inhibitor as phenelizine is the:

    High risk of hypertensive crisis.

    Q45. An inverse agonist drug means a drug that:

    Reduces the activity of a receptor that was active in the absence of agonist.

    Q46. Which of the following statements about neurotransmission in central nervous

    system is TRUE?

    G-protein coupled receptors are example of metabotropic receptors.

    Q47. You have the following 3 general anesthetics with their [blood : gas partition

    coefficient (BGPC)] and [minimal alveolar concentration (MAC)]:

  • CNS theory exam .. EHSAN 2014

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    Drug X:--------- BGPC = 2%------------ MAC = 5%

    Drug Y:-------- BGPC = 0.7%---------- MAC = 33%

    Drug Z:--------- BGPC = 3.5%----------MAC = 90%

    The drug that has the least solubility in the blood is drug ____ , and the drug that has

    the least potency is drug ___ . (Choose the best answer to fill both blanks,

    respectively):

    Y , Z, X

    Q48. A 27 years-old male came to Emergency room with dyspnea, low blood

    pressure, and purple skin. Upon examination, his blood pressure was 90/45, and his

    respiratory rate was 3 shallow breaths per minute, and extremely small pupils (i.e.

    Miosis). There were marks of needle injections on his left arm. The drug of choice to

    reverse these symptoms is:

    Naloxone

    is useful both in acute opioid overdose and in reducing respiratory NaloxoneNOTE>>

    or mental depression due to opioids.

    Opiate overdose symptoms and signs include: decreased level of consciousness and

    pinpoint pupils. Heart rate and breathing slow down, sometimes to a stop. Other

    symptoms include seizures and muscle spasms. A person experiencing an opiate

    overdose usually will not wake up even if their name is called or if they are shaken

    vigorously

    Q49. Identify the INCORRECT match between the general anesthetic and its

    property:

    Thiopental ------------------ Anterograde amnesia.

    anterograde amnesia mostly caused by benzodiazepine drugs and Alcohol NOTE>>

    intoxication.

    Thiopental is an anesthetic drug that has S/Es like cardiovascular and respiratory

    depression , prolonged somnolence and nausea.

  • CNS theory exam .. EHSAN 2014

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    Q50. One of the following is FALSE regarding opioid agonists:

    Remifentanyl has very long duration of action.

    id analgesic drug. It is given to patients acting synthetic opio-is a potent, short NOTE>>

    during surgery to relieve pain and as an adjunct to an anaesthetic.

    Q51. Identify the CORRECT match between the drug and its mechanism of action:

    Methylxanthins ----------- Inhibit phosphodiesterase (PDE)

    Methylxanthines are bronchodilators used in the treatment of asthma and NOTE>>

    chronic obstructive pulmonary disease (COPD)

    Q52. A third year medical student started to play FIFA 2014 video game on a daily

    basis for at least 6 hours. It affected his academic performance by being absent

    from lectures, and getting very low grades in the exams. He continued playing this

    game regardless of the adverse consequences. This is an example of:

    Addiction.

    PHYSIOLOGY

    Q53. Which of the following is INCORRECT regarding the cerebral blood flow?

    It is controlled mainly through the autonomic system.

    is the blood supply to the brain in a given period of time.NOTE&