N53 ATI PHARM 207637583-Ati-Pharmacology.doc

8/11/2019 N53 ATI PHARM 207637583-Ati-Pharmacology.doc

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treat HTN by blocking conversion of

angiotensin I to angiotensin II

ACE inhibitors (lisinoPRIL)

treat HTN by blocking the binding of

angiotensin II to recetors in tiss!es

AR"# (lo#ARTAN)

$lisinoPRIL ACE inhibitors

$lo#ARTAN AR"#

%hat to &onitor %hen taking ACE (lisinoPRIL)

'AR"# ( lo#ARTAN)

&onitor levels* blood ress!re and

angiode&a (give ei s!b+)

sto di!retics ,-$-. hrs before starting ACE inhibitors (lisinoPRIL)

ACE (lisinoPRIL) &ay ca!se/ ersistent non rod!ctive co!gh

side e0ects incl!de/ angiode&a (ad&inister ei

s!b+) and hyotension $ sho!ld not be !sed in

the ,nd'1rd tri&ester of regnancy

ACE inhib(lisinoPRIL) ' AR"s (lo#ARTAN)

AR" that sho!ld be taken 2 ho!r before &eals catoPRIL

slo%s &ove&ent of calci!& into s&ooth

&!scle cells ca!sing arterial dilation and

decreased "P

calci!& channel blockers (CC"s)

a&lo3IPINE* veraa&il* cardi4e& CC"s

!sed to treat angina and HTN CC"s/ a&lo3IPINE* veraa&il* cardi4e&

&ay be !sed to treat a5b* a6!tter or #7T veraa&il and dilta4e&

reca!tions'interactions in CC"s/ a&lo3IPINE*

veraa&il* cardi4e&

ts taking digo8in and beta$blockers9

heart fail!re* heart block or bradycardia9

do not cons!&e graefr!it :!ice


2/26


3/26

barbit!ates or s!lfona&ides aldo&et)

lactating &others sho!ld not !se these

antihyertensives

alha$, agonists (catares* tene8*

aldo&et)

dry &o!th* dro%siness'sedation* rebo!nd HTN*

black'sore tong!e* le!koenia

side e0ects of alha$, agonists (catares*

tene8* aldo&et)

ts sho!ld notify the hysician of this %hen

taking alha$, agonists (catares* tene8*

aldo&et)

invol!ntary :erky &ove&ent* rolonged

di44iness* rash* yello%ing of the skin

decrease/ cardiac e8citability* cardiac o!t!t*

and &yocardial o8ygen de&and9 lo%er "P by

decrease release of renin in the kidney

beta$blockers (&etor=L=L)

beta$blockers (&etor=L=L) are

contraindicated in ts %ith

A7 block* or chronic resiratory diseases

;;;;;;; (beta$blocker) &ay &aks signs of

hyoglyce&ia in diabetics

roan=L=L

do not ad&inister labet=L=L in the sa&e line

%ith >

f!rose&ide

side e0ects of beta$blockers (&etor=L=L) bradycardia* nasal st!@ness* A7 block*

bronchosas&

hold beta$blockers (&etor=L=L) %hen #"P

;;;; or HR ;;;;;

#"P 2BB ' HR B

nitro* nicardIPINE* vasotec I7* es&olol are> vasodilators

!sed in HTN e&ergencies b'c they directly

dilate arteries and veins res!lting in decreased

reload and afterload

vasodilators (nitro* nicardIPINE* vasotec

I7* es&olol)


4/26

vasodilators (nitro* nicardIPINE* vasotec I7*

es&olol) sho!ld not be !sed in ts %ith>

heatic'renal disease* old age* electrolyte

i&balances

side e0ects of vasodilators (nitro* nicardIPINE*

vasotec I7* es&olol)

di44iness* HA* rofo!nd hyotension*

cyanide to8icity*

nitror!sside &ay not be &i8ed %ith ;;; any other &eds

cardiac glycosides digo8in

increases the force in velocity of heart

contractions to i&rove stroke vol!&e (DB&L)

and cardiac o!t!t and slo% cond!ction rate

digo8in

!sed to treat heart fail!re and a5b digo8in

;;;;;;;;; &eds increase risk of hyokale&ia

and reciitate digo8in to8icity

thia4ide' loo di!retics* AR"s

(lo#ARTAN) 'ACE inhibitors (lisinoPRIL)

signs of digo8in to8icity Early signs of to8icity/ FI !set/

Anore8ia* N'7'3*

Late signs of to8icity/ HA* vis!al

dist!rbances* HR abnor&alities

nor&al ser!& digo8in level BG. $ ,

ad&inister ;;;; for digo8in overdose digibind

in digo8in to8icity %hat sho!ld dysryhth&ias be

treated %ith %hen digo8in is stoed

dilantin

slo%s cond!ction ti&e thro!gh the A7 node*interr!ts A7 node ath%ays to restore N#R

adenosine

rolongs reolari4ation* rela8es s&ooth

&!scles* decreases vasc!lar resistance

a&iodorone

increases 5ring of the #A node and cond!ction atroine


5/26

thro!gh the A7 node$ ooses action of the

vag!s nerve

convert s!raventric!lar tachycardia (#7T) to

N#R

adenosine

treat 7$ib* !nstable ventriv!lar tachycardia a&iodarone

treat asystole* bradycardia atroine

anti$hyerliide&ia &eds statins

;;;; &ay ca!se rolonged bleeding in ts take

co!&adin

statins

do not ad&inister statins %ith ;;;;;> graefr!it :!ice

inhibits the absortion of cholesterol 4etia

%hen sho!ld 4etia be taken 2 ho!rs before or - ho!rs after statins

short$acting inhaler for ac!te bronchosas& alb!terol

long acting inhaler for for long$ter& control of

asth&a

foradil* serevent

oral* long acting beta$, adrenergic agonists

(bronchodilator) !sed for long$ter& control of

asth&a

terb!taline

;;;;;; &eds that %ill increases the e0ect of

bronchodilators

?A=Is

ca!ses rela8ation of bronchial s&ooth &!scle

ca!sing bronchodilation !sed for long ter&

control of asth&a

theoPHLLINE

;;;;;; and ;;;;;; decrease theoPHLLIN levels henobarbitol and henytoin


6/26

therae!tic level of theoPHLLINE 2B$,B &cg'&L

treat&ents of theoPHLLINE to8icity activated charcoal to decrease

absortion* lidocaine for dysrhyth&ias

and dia4ea& for sei4!res

inhaled anticholinergics ca!sing

bronchodilation

iratr=PIJ?

iratr=PIJ? is contraindicated in ts %ith a

;;;;;; allergy

ean!t

!se iratr=PIJ? %ith e8tre&e ca!tion in

atients %ith ;;;;;; and ;;;;;;

ac!te angle gla!co&e and "PH

side e0ects of iratr=PIJ? dry &o!th'eyes and !rinary retention

do not take gl!cocorticoids %ith ;;;;;;; N#AI3s

revents e0ects of le!kotrienes ca!sing

decreased/ in6a&&ation* bronchoconstriction*

air%ay ede&a* and &!c!s rod!ction

sing!lair* 4y6o

;;;;;;;; %ill decrease the circ!lating e0ects of

sing!lar

henobarbital

side e0ects of sing!lair and 4y6o elevated LTs* %arfarin and theohylline

to8icity

slo%s carb absortion and digestion*

contraindicated in ts %ith intestinal disease

Precose* Flyset

red!ces gl!coneogeneis* increases gl!cose!take by &!scles

&etfor&in

ro&otes release of ins!lin* lo%ers gl!cagon

secretions and slo%s gastric e&tying

Kan!via

Kan!via dose sho!ld be red!ced in atients %ith i&aired renal f!nction


7/26

diabetes &ed that sho!ld be %ithheld for -.

hrs rior to and after contrast

&etfor&in

&etfor&in is contraindicated in atients %ith severe infection* shock* hyo8ic

conditions

red!ces rod!ction of gl!cose and sho!ld not

be !sed %ith NPH

randin* starli8

ro&otes release of ins!lin fro& the ancreas glii4ide* glyb!ride

these diabetes &eds ca!se high risk for

hyoglyce&ia in ts %ith renal* heatic or

adrenal disorders

glii4ide* glyb!ride

oral &edications that decreases ins!lin

resistance

Avandia* Actos

oral diabetes &edications that have a high risk

for CH d!e to 6!id retention

Avandia* Actos

onset of h!&alog less than 2 &in

eak of h!&alog 1B$B &in

d!ration of h!&alog 1$- ho!rs

onsent of reg!lar ins!lin 1B$B &in

eak of reg!lar ins!lin ,$1 ho!rs

d!ration of reg!lar ins!lin $D ho!rs

onset of NPH 2$, ho!rs

eak of NPH -$2, ho!rs


8/26

d!ration of NPH 2.$,- ho!rs

onset of lant!s 2 ho!r

eak of lant!s none

d!ration of lant!s 2B$,- ho!rs

3ra%ing$! reg!lar and NPH ins!lin N$R$R$N

2G In:ect air into NPH

,G In:ect air into reg!lar

1G 3ra% ! reg!lar ins!lin

-G 3ra% ! NPH

%hen sho!ld lant!s be ad&inistered at bedti&e

do not &i8 other ins!lins %ith h!&alog* lant!s or co&bination ins!lins

the only ins!lin given I7 reg!lar

glyce&ic agent that breaksdo%n glycogen into

gl!cose in the liver

gl!cagon

gl!cagon sho!ld not be &i8ed %ith ;;;;; and

;;;; sol!tions

sodi!& or de8trose

sti&!lates the &etabolis& of all body syste&s

acclerating the rate of cell!lar o8ygenation

synthroid

side e0ects of synthroid' signs of

hyerthyroidis&

tachycardia* restlessness* diarrhea* %t

loss* decrease bone density* heat

intolerance* inso&nia

inhibits synthesis of thyroid hor&one Taa4ole

increases rod!ction of ins!lin$like gro%th

factor

so&at=TR=PIN

avoid !se of ;;;;; %hen taking so&at=TR=PIN gl!ccocorticoids


9/26

so&at=TR=PIN is ad&inistered s!b+

ro&otes reabsortion of %ater %ith the

kidneys9 vasocontriction of vasc!lar s&ooth

&!scle

des&oPRE##IN

des&oPRE##IN is !sed to T8 diabetes insiid!s* cardiac arrest and

noct!rnal en!resis

side e0ects of des&oPRE##IN hyonatre&ia* sei4!res and co&a

blood rod!ct !sed to relace vol!&e %hole blood (,$- hr)

blood rod!ct !sed to T8 severe ane&ia*

he&olytic ane&ia* erythroblastosis

acked R"Cs (,$- hr)

blood rod!ct to T8 active bleeding* alastic

ane&ia* and bone &arro% s!oression

latelets (2$1B &in)

blood rod!ct !sed to T8 he&orrhage* b!rns*

shock* TTP* and reverse e0ects of %arfain

P

sti&!lates R"C rod!ction Procrit

sti&!lates M"C rod!ction &ay ca!se bone

ain or le!kocytosis

Ne!ogen* Ne!lasta

sti&!lates latelet rod!ction Ne!&ega

hold digo8in if an infants !lse is less than B

hold digo8in if a childOs !lse is less than DB

%hen to delay He " va8 allergy to bakerOs yeast* liver disease

%hen to delay 3TaP va8 1B days after i&&!nos!ression


10/26


11/26

%hen taking "actri& and #etra> cons!&e at least 1L of %ater* !se back$

! contracetives* avoid s!n e8os!re

%hen taking tetraCCLINEs cons!&e at least 1L of %ater* !se back$

! contracetives* avoid s!n e8os!re

do not give ;;;;;; to children less than . d!e to

er&anent teeth discoloration

tetraCCLINEs

;;;;;;;; ca!ses gingivitis* gingival hyerlasia 3ilantin

%hat 7a8 are needed by age 3Ta* IP7* ??R* 7aricella*

&onitor heatic'renal f!nction* refrigerate

s!sensions* increased risk - bleeding in ts

taking anticoag!lants

3i6!can

&onitor for dr!g ind!ced retinoathy in ts

taking

laS!enil* S!inine

!sed for revention and T8 of T" INH* rifa&in

recations %hen taking ;;;;;;; incl!de/

risk of ne!roathies'heatoto8icity

cons!&e "

avoid alcholol

INH

avoid eating ;;;;; and taking ;;;;;; %hen on

INH

tyra&ine ' dilantin

;;;;;;;; %ill ca!se discoloration of !rine* saliva*s%eat and tears

rifa&in

ad&inister this antiretroviral on an e&ty

sto&ach

A


12/26

%hen taking any antiretroviral

2G>

,G>

increase 6!id intake

begin theray %ith 5rst onset of

sy&to&s

osteoorosis &eds (boniva* 4o&eta) absortion

is decreased %hen taken %ithGGGGGG

calci!&* =K* antacids* ca0eine

osteoorosis &eds (boniva* 4o&eta) sho!ld be

ad&inistered

in the A? on an e&ty sto&ach

this &ed !sed to T8 rhe!&atoid arthritis is

contraindicated in regnancy* renal'liver fail!re*

soriasis* blood disorders

3?AR3s

this &ed (3?AR3) !sed to T8 rhe!&atoid

arthritis &ay ca!se increased risk for infection*

bone &arro% s!ression* FI !lceration

&ethotre8ate

laS!enil &ay ca!se retinal da&age (blindness)

go!t &ed that inhibits !rac acid rod!ction

!sed to treat ACJTE go!t

allo!rinol

go!t &ed that inhibits rocesses to revent

le!kocytes fro& invading :oints !sed to treat

CHR=NIC go!t

colchine

go!t &eds are contraindicated in ts %ith>>>> renal* cardiac and FI dysf!nction

avoid ;;;;; %hen taking &eds for go!t A#A

na&e - antian8iety &eds lora


13/26


14/26

instr!ct client to take ;;;;;;; antideressants in

the A?

##RIs (aroETINE* le8aro* l!vo8* 4oloft)

;;;;;; and ;;;;; %ill increase lithi!& levels N#AI3s and A#A

&onitor ser!& ;;;;; levels %hen taking lithi!& sodi!&

therae!tic level of lithi!& BG- $ 2&ES'L

therae!tic e0ects of lithi!& begin in ;;; to ;;;

days

D to 2-

%hat is the lithi!& to8icity level>

#8/ FI distress* &ental conf!sion* oor

coordination* coarse tre&ors

2G to ,/ &oderate to advanced

%hat is the lithi!& to8icity level>

#8/ ata8ia* conf!sion* increased dil!te !rine

o!t!t* bl!rred vision* clonic &ove&ents*

sei4!res* st!or* severe hyotension* and

co&a* !l&onary co&lications &ay lead to

death $ !se ;;;;;;; to increase rate of e8cretion

,/ severe $ &annitol

ac!te dyskinesias and dystonic reactions*

tardive dyskinesia* Parkinsonis&* akinesia*

akathisia* and ne!roletic &alignant syndro&e

are>>>

e8trayra&idal e0ects of conventional

(haldol* thora4ine* nacene) antisychotics

a disorder res!lting in invol!ntary* reetitive

body &ove&ents

tardive dyskinesia

Co&&on sy&to&s incl!de/

3ecrease in facial e8ressions

3i@c!lty starting and controlling &ove&ent

Loss or %eakness of &ove&ent (aralysis)

#oft voice

#ti0ness of the tr!nk* ar&s* or legs

Parkinsonis&


15/26

Tre&or

absence* overty* or loss of control of vol!ntary

&!scle &ove&ents

akinesia

a disorder in %hich there is an !rge or need to

&ove the legs to sto !nleasant sensations

akathisia

#y&to&s incl!de high fever* s%eating*

!nstable blood ress!re* st!or* &!sc!lar

rigidity* and a!tono&ic dysf!nctionG

ne!roletic &alignant syndro&e

#y&to&s occ!r %ithin &in!tes to ho!rs of

taking (aroETINE* le8aro* l!vo8* 4oloft)* and

&ay incl!de/

Agitation or restlessness

3iarrhea

ast heart beat

Hall!cinations

Increased body te&erat!re

Loss of coordination

Na!sea

=veractive re6e8es

Raid changes in blood ress!re

7o&iting

serotonin syndro&e

!sed to &aintain sobriety in T8 of alcoholis& antab!se

do not give antab!se %ithin ;;;; days of

drinking alcohol

2- days

&edications !sed to treat &ysasthenia gravis Prostg&in* ?ytelase* Tensilon

do not ad&inister &yasthenia gravis &eds if

systolic "P is belo%

B

" decreases the e0ects of this arkinsonOs

&ed

levodoa


16/26

;;;;;;; ca!ses increased e8cretion of digo8in*

%arfarin* and =CP

3ilantin

therae!tic range for 3ilantin 2B$,B

do not take Ti&otic %hen !sing CC"s and beta$blockers

;;;;;; oiod is contraindicated after biliary

tract s!rgery

&orhine

;;;;;;; oiod is contraindicated in clients %ith

renal fail!re

3e&erol

therae!tic level of &agnesi!& s!lfate -$.

act on !terine &!scle to sto contractions tocolytics (brethine* rocardia* &ag

s!lfate)

signs of &agnesi!& s!lfate to8icity 3eressed 3TR (dee tendon re6e8)

$ Resiratory deression

$ Co&a

$ Cardiac arrest

$ 3eathG

if yo! s!sect &ag to8icity > ad&inister Calci!& Fl!conateG

3ecreased a&&onia level i&rove&ent in ts %ith heatic

encehaloathy

?!scle sas&s indicate hyo or

hyercalcae&ia

hyocalcae&ia

#8 of hyo or hyer calce&iaLethargy* %eakness* fatig!e* conf!sion* %t loss*

bone ain* cardiac dysrhyth&ias and kidney

stone

hyercalce&ia

;;;;;;;;%ill be elevated in bone or liver disease

and is also raised by alcohol and heatoto8ic

FFT


17/26

dr!gs

A 6atted T %ave is indicated of > hyokale&ia

a&inoglycosides (genta?CIN* vanco?CIN)

are ad&inistered I7 over ;;;;;;;; (ti&e)

2 ho!r

a vasoressor !sed in the T8 of shock and

heart fail!reG

increases cardiac o!t!t by increasing

&yocardial contractility

Ualso dilates renal blood vessels* %hich increase

renal rof!sion leading to increased !rine

o!t!t

doa&ine

therae!tic e0ect of doa&ine increased !rine o!t!t d!e to dilated

renal blood vessles and increased renal

erf!sion

side e0ects of doa&ine increased !lse

HTN

dysrhyth&ias

!sed to correct hyotension that is

!nresonsive to adeS!ate 6!id vol!&e

relace&ent or occ!rs as art of shock

syndro&e ca!sed by bactere&ia* chronic

cardiac deco&ensation* dr!g overdose* ?I*

oen$heart s!rgery* renal fail!re* tra!&a* or

other &a:or syste&ic illnesses9 to i&rove lo%

cardiac o!t!t

vasoressors (doa&ine)

Mhere is Penicillin F ad&inistered> PCN F is very irritating and sho!ld be

in:ected into a large &!scle (ventral

gl!teal ' vast!s lateralis) !sing a ,,$,F 2

$2 2',V needle and sho!ld be

ad&inistered dee

%hy is ?ag s!lfate is ad&inistered to re$ to revent sei4!res


18/26

ecla&sia ts>

the best evidence of therae!tic resonse to

Plavi8 is

absence of angina* neck':a% ain and

absence of di@c!lty s%allo%ing

ts %ith an allergy to PCNs &ay also have an

allergy to this ab8 class

CEPH'alosorins

N#AI3s ;;;;;;; di!retic e0ects red!ce

to8ic levels of ;;;;;;;; can ca!se

diloia'do!ble vision* HA* and vertigoG #er!&

sodi!& levels can be i&acted and !rine

o!t!t decreased

?edication !sed for alcohol %ithdra% are Libri!&

Elavil* is a antideressant* the side e0ects are =rthostatic hyotension* di44iness* get !

Q &ove slo%ly* ?onitor "P* Q heart rate

before* and 2 ho!r after ad&inistering* if

decrease in heart rate* hold &eds Q notify

3octorG

Elavil* Theray Relief can take 2 to 1 %eeks* and ossibly

, to 1 &onths for f!ll bene5tG

Elavil* also e0ects Jrinary retention* dry &o!th* bl!rred

vision* hotohobia* constiation*

tachycardia

Proranolol* as Inderal* is a "eta "locker 3o not sto ab!rtly* client sho!ld &onitor

heart* and "lood Press!re daily* Treats*

hyerthyroidis&* &igraine* and gla!co&a

Proranolol* Inderal #ide E0ect "radycardia* !lse rate belo% B* hold

&edication Q call 3octor* 3iabetics can

&ask tachycardia* &onitor gl!cose to

detect hyoglyce&ia* 3ecreased cardiac


19/26

o!t!t signs* are shortness of breath*

ede&a* fatig!e* =rthostatic hyotension*

faintness* Avoid in client %ith asth&a

Lisinoril* as Prinivil is a Ace Inhibitorfor "lood Press!re

Treats* Hyotension* heart fail!re*&yocardial infraction* it decreases the left

ventric!lar dysf!nction

Lisinoril* side e0ects are Ca!ses a 3ry co!gh* sto &edsG* notify

3octor*

hyerkale&ia* &onitor otassi!&*

e8ected range 1G to * Rash Q

dysge!sia* as altered taste*

Angioede&a is a s%ollen tong!e* and oral

haryn8* side e0ects are treated %ith

in:ection of Einehrine

3ystonia #as& #!stained* invol!ntary &!scle

contractions

3antri!&* is a #keletal ?!scle Rela8ant Treats ?alignant hyerther&ia* sti0ness*

and sas&s* can occ!r d!ring s!rgery

%ith certain tyes of anesthesiaG

Cehalosorin* is a "road setr!& bacterial

&edG

Treats Jrinary tract infection* ost

oerative infection* Q elvic infection

Iron s!le&ent Need to take %ith 7iti&in C* olike orange

:!i8ce* to increase absortion* Avoid &ilk*

Q calci!&* it interferes %ith absortion*

!se a stra% it can stain teeth* ?ay ca!se

black stools and constiation

Nitroress is !sed to treat congestive heart fail!re*

and life threatening high blood ress!re*

as hyertensionG

?yasthenia Fravis* Treat&ent 3r!gs It e0ects the &!scles of the eyes* face*

&o!th* throat* neckG Me &ay see facial


20/26

drooing* dr!gs !sed are Neostig&ine* as

rostig&ine

3ilantin* adverse e0ects are Hyerlasia* as bleeding F!&s* RashG*

and3ilantin #ide E0ect* is Hair loss

3ilantin* 3r!g interaction %ith =ral contracetives* Co!&adin* and

Fl!ccocorticordsG*

3ilantin are !sed to control #ei4!res

Ti&olol Is a beta blocker* that is !sed for

treat&ent of gla!co&a*

as I=P of the eyes

Probenecid* interacts %ith Anti go!t &edications* it revents re

absortion of !ric acid Fo!t* it also

inhibits the secretion of enicillin

Pinicillin Interacts %ith Asirin* and A&inoglycosides* %hen

&i8ed in the sa&e I 7 sol!tion

Co!&adin kno%n as %arfarin INR/ ,$1* a anticoag!lant* revention of

blood clotsG

?eds that interact* %ith co!&adin are

Hearin* 3ilantin* Q Aceta&inohen as

tylenol* and Asirin

Hearin* Thera!etic Range B to .B* inhibits the clotting rocessG*

latelet !nder 2B*BBB* sto &edication

Hearin* I 7 3ri LabG 7al!e ?onitor aPTT 2G to ,G* ad&inister slo%ly*

no &ore than ,B&g er &in!te* and

B&g er 2B &in!teG*

3igo8in* a cardiac glycoside 7al!e are 2G to ,GB* ?onitor otassi!&

levels*

The dr!g Lasi8* interacts %ith digo8in* and


21/26

increases to8icity

3igo8in* #ide E0ects are Anore8ia* tachycardia* bradycardia* and

heart block

Ta&o8ifen* A Cancer dr!g* a =ral ?edication Estrogen Recetor "locker* #tos gro%th

of "reast Cancer* #ide E0ect are*

Endo&etrial Cancer* abnor&al bleedingG*

Hyrecalce&ia* &ontior calci!& levelsG*

P!l&onary E&bol!s* shortness of breath*

and chest ainG

entanyl* is a Narcotic Analgesic It is &ore otent than &orhine* yo!

need a %ritten rescrition for& Physician

Theohylline* 3r!g A bronchodilator to treat asth&a*

bronchitis* e&hyse&a* %hich Interacts

%ith ca0eine

Cro&oly& #odi!&* as Intal Inhaler Is a anti in6a&&atory* a Long acting

control of asth&a*

Mait 2 &in!te after !se for activity* or

e8os!re to allergen

Alb!terol* is !sed for e8ercise ind!ced Asth&a Jse the Alb!terol inhaler 5rst9 then %ait

abo!t &in!tes before !sing the steroid

inhalerG* This allo%s the Alb!terol to oen

! yo!r air%ays* so the steroid can %ork

betterG

Antihesti&ine* as "enadryl Ca!ses sleeiness

PTJ* Interacts %ith 3igo8in* ?ay increase gl!coside levels

PTJ* side e0ects Hyothyroidis&* Meight gain*

"radycardia* Anore8ia* cold intolerance*

heatic to8icityG* agran!locytosis is RARE*

b!t ca!se sore throat* Q fever


22/26

Loid ibrates* for Cholesterol Test ?onitor "aseline Liver f!nction* Q Renal

f!nction test

"ihoshonates "oniva* adds calci!& to bones for

osteoorosis* Take on e&ty sto&achG* sit!right for 1B &in!tes after takingG* No

food* or calci!& s!le&ents %ithin an

ho!r of taking &edicationG* Not for atient

%ith hyocale&ia* it can ca!ses cardiac

arrest

?ethotre8ate* a Rhe!&atoid Arthiritis ?ed*

interact %ith

N#AI3* Q #!lfona&ides* &ay ca!se

To8icity* &onitor levels

Rhe!&atoid Arthiritis* indings to Reort Patient sho!ld be tested for t!berc!losis

5rst* and any active infection* or 6!

Rhe!&atoid Arthiritis ?edG Adverse E0ects Are at risk for infection* fever* sore throat*

fetal death* heatic 5brosis* and sho!ld

&onitor liver f!nction

Ergostat* ?edication Treats &igraines

Ergostat* #ide E0ect are etal abortion* FI disco&fort* na!sea*

vo&itingG*

Ergotis&* are &!scle ainG* Paresthesias*

cold 5ngers Q toes

"yetta* is a 3iabetes ?ellit!s*

They are re5lled in:ection en

Mhich can ca!se Pancreatitis* and severe

abdo&inal ain* sto &edication* and

notify doctorG* It also ca!ses F I e0ectsG*

"yetta needs in:ected 2 ho!r rior to

&eals* NE7ER INKECT ATER ?EAL* store

in refridgarator

Antivirals* &edications treat HI7* heres* Heatitis "* C* In6!en4a A Q

"*

#lo%s do%n viral load* and allo%s the T

cells levels to stay nor&alG* Alha


23/26

interferons inhibit sread of vir!ses to

ne% cells

Rifa&in A treat&ent given to T" atients* it is

taken in con:!nction %ith the other 5rstline &edication* This can ca!se =RANFE

C=L=RE3 JRINE* and er&enant

discoloration of soft contact lensesG

Potassi!& Inf!sion Five no faster than 2B&ES er ho!r and*

val!e level 1G to GB

If there is a &edication error Check atients vital signs 5rst

Che&o 3r!gs* contraindication are Liver* kidney* %o&en regnant* and

atient that %ith i&&!nos!ression

Fara&yci&* is a Antibiotic Protien synthesis #ide E0ect* hearing lossG* Interacts %ith

&ilk* calci!&* anatcids* and iron

s!le&entsG* take 2 ho!r before &eals

on a e&ty sto&ach

Levodoa* a Anti ParkinsonOs dr!g It is converted into doa&ine in the brain*

%hich increases intraoc!lar ress!re* and

is contraindicated in closed angle

gla!co&a

Ne!rologic 3r!gs* as 3ilantin kno%n as

Phenytoin* interacts %ith

?A=Is* Co!&adin* =ral contracetives*

CN# deressants* and graefr!it :!ice

"lood Press!re ?eds* as 3e&erol* ?orhine* Q

entanyl* adverse e0ects

Are Resiratory deression* and

hyotension

Ca!tion of =lder atients ?edications e0ect older atients liver*

renal* F I* blood

Hearin* Adverse E0ects "r!ising* etichiae* bleeding* and

Thro&bocytoenia* lo% latelet


24/26

Hearin* in:ections are Fiven s!bc!taneo!s* , inches fro& the

!&bilic!s* aly ress!re for 2 to ,

&in!tes after in:ection* Hearin is a anti

clotting s!bstance for&ed by tiss!e cells*

esecially the liver9 a antirothro&bin

"enadryl* is a Antihista&ine H 2 Recetor #ide E0ects are #leeiness* and dry

&o!th

"acteria Cell Mall ?edications Are in:ected I ? in the b!ttlock &!scle

area* ca!tion %ith in:ecting arteries

"2, 3e5ciency* #igns Are Ne!roathy* beefy tong!e* Patients

need to adhere to Lab tests* and blood

co!nt levels

"2, 3e5ciency* Treat&ent Cyanocobala&in as cobala&in in:ection*

Teach atient to eat green leafy

vegetables

"2, 3e5ciency* ca!ses Hyokale&ia* &onitor otassi!& levels*

also ernicio!s ane&ia* gastric byass*

acid s!ression* CrohnOs* tae%or&* and

ile!& resection

Antilie&ic* as Liitor* and*


25/26

s!scetible ersons receive certain

anesthetic dr!gsG

?alignant Hyerther&ia* is treated %ith 3antri!&

antihychotic dr!gs* as Haldol* Thora4ine*

#ide e0ects

Are 3ystonia* sas&* neck sas&

Che&o 3r!gs* Adverse E0ects Are Hair loss* na!sea* vo&iting*

diarrehea* and lo% %hite blood cells

3i!retics* as Lasi8* Q =s&itrol* #ide E0ects Are 3ehydration* and Hyokale&ia*

ca!ses lo% otassi!&* &onitor

otassi!&* if belo% 1G2 notify doctor

Calci!& channel "lockers* as 7eraa&il*

side E0ects

Are ede&a* hyotension* do not drink

graefr!it :!ice

=s&ostic 3i!retics* as =s&itrol treats Red!ces the intracranial ress!re of the

eye

7ita&in is a antidote for Patient* on co!&adin* and e8erience

bleeding

Al4hei&ers taking 3onee4il #ide E0ect Is dysnea* ca!ses bronchconstrictionG*

N!rse sho!ld notify doctor

Libri!& ?edication Prevents deliri!& tre&ors

etrorolac Q Toradol #ide E0ects Increase risk of bleedingG* check for

bri!singG* Take %ith food

"etaace ?edication Is !sed to decrease heart rate

I&d!r #ho!ld be given* if atients blood

ress!re is less than B

Narcan Is taking to revent hyotensionG* To %ake


26/26

! atient

Pilocar Is !sed to treat gla!co&a* the rest of the

atients life

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N53 ATI PHARM 207637583-Ati-Pharmacology.doc