More Organic Chemistry:

Proteinsand DNA

Proteins• Enzymes

• Structural proteins

• Storage proteins

• Transport proteins

• Hormones

• Receptors

• Contractile proteins

• Defensive proteins.

Amino Acids

amino

Amino Acids

N

amino

Amino Acids

acid

N C

O

O

amino

Amino Acids

acid

N C C

O

O

amino

Amino Acids

acid

N C C

O

O

R

H

NH2—C—COOH

R

Amino Acids

20 different amino acids:

• Polar or nonpolar

• Electrically charged or not.

Amino Acids

Peptide Bonds

Peptide Bonds

Peptide Bonds

Peptide Bonds

Peptide Bonds

Peptide Bonds

Peptide Bonds

• Primary

• Secondary

• Tertiary

•Quaternary.

Levels of Structure:

Primary Structure

Primary Structure

in a hole in the ground there lived a hobbit not a nasty dirty wet hole filled with the ends of worms and an oozy smell nor yet a dry bare sandy hole with nothing in it to sit down on or to eat it was a hobbit hole and that means comfort

Secondary StructureChapter One

In a hole in the ground there lived

a hobbit. Not a nasty, dirty, wet hole, filled with the ends of worms and an oozy smell, nor yet a dry, bare, sandy hole with nothing in it to sit down on or to eat: it was a hobbit-hole, and that means comfort.

Tertiary Structure

Quaternary Structure

Primary Structure

Secondary Structure

Tertiary Structure

Quaternary Structure

Protein Structure

Protein Structure

Mutant Proteins

Denatured Proteins

Nucleic Acids

Nucleic Acids

Concept Check Questions

Why does a denatured protein no longer

function normally?

Concept Check Questions

A genetic mutation may change a protein’s

primary structure. Why does this destroy the

protein’s function?

Concept Check Questions

In a DNA double helix, one strand has the sequence:

5’-TAGGCCT-3’List the sequence along the

other strand, clearly indicating 3’ and 5’ ends of the strand.

.