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Modern Genetics
• DNA structure, RNA Structure• DNA Function, RNA Function
• Protein Synthesis (transcription & translation)• Mutations & the Effects of Mutations• Biotechnology & Genetic Engineering
http://www.dnalc.org/resources/3d/index.html
http://www.dnalc.org/resources/3d/index.html
Nucleic Acids Large complex molecules that store and transmit genetic information.
DNA
• What is it?
• What does it do?
• What does it look like?
xray chrystallagraphy pictures taken by Rosalind Franklin
Double helix structure of DNA proposed by James Watson & Francis Crick
RNA Ribonucleic Acid• What is it?• What kinds of RNA are there and what do they do? • What does it look like?
Organization of DNA in Cells
DNA Replication
https://www.dnalc.org/resources/3d/
1. DNA uncoils and the two strands unzip. The hydrogen bonds between the base pairs break and the two strands of the DNA separate.
2. Free nucleotides move in and bind with the parent DNA strands (the DNA template). Complementary bases bind to the open bases on the template strands.
3. The free nucleotides in the new strands bind together. The copied DNA recoils. The two DNA molecules are identical.
4. The structure of the DNA molecule (two complementary strands that can separate between the base pairs) ensures that the DNA is copied efficiently (quickly and correctly).
https://www.dnalc.org/resources/3d/
http://www.pbs.org/wgbh/aso/tryit/dna/
Read about:DNA Replication Protein SynthesisDo DNA Workshop Activity
Vocabulary:DNADNA replicationRNA (mRNA, tRNA, rRNA)protein synthesistranscriptiontranslationribosomecodonanticodonmutation
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