Medicinal Chemistry And Drug Discovery & Development India ...mcaddi.com/images/Brochure_MCADDI_2019.pdf · Electronic City, Phase II, Hosur Road, Bengaluru, Karnataka 560100 Date:

I U P A C

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Medicinal Chemistry And Drug Discovery & Development India 2019 (MCADDI 2019)

Venue: Neville Bain Training Center,

Biocon Academy, Biocon House, Semicon Park,

Electronic City, Phase II, Hosur Road, Bengaluru, Karnataka 560100

Date: March 04th - 09th, 2019

Biocon Academy, in associa�on with American Chemical Society (ACS) Medicinal

Chemistry Division (MEDI) and Pharma Innova�on Sourcing Center LLC, USA proudly

announce the residen�al course, Medicinal Chemistry and Drug Discovery &

Development India 2019 (MCADDI2019) to be held in March 2019 at the Biocon

Academy campus in Bangalore, India. The five days program will be co-sponsored by

the ACS MEDI Division and the Human Health Division of Interna�onal Union of Pure

and Applied Chemistry (IUPAC). MCADDI 2019 builds on the successful MCADDI 2017

course which was also held at the Biocon Academy Campus and drew over 100

a�endees from industry and academia.

MCADDI 2019 willpresenttheprinciplesofMedicinalChemistry,

DrugDiscovery&Development ina format that isdesigned for

industrialandacademicpar�cipantswhoarecurrentlyworkingin

thisarea,orplantodoso.Thecoursewillincludethirtylectureson

target iden�fica�on and valida�on, lead op�miza�on, drug

metabolism and pharmacokine�cs, molecular modelling,

bioisosteres, structure based drug design, drug-like proper�es,

pharmaceu�cs,discoveryofbiologicsandothertopicsofinterest

todrugdiscovery&developmentscien�sts.InMCADDI2019,we

havededicatedseverallecturesonpharmaceu�caldevelopment

CMCtopicsincludingprocessop�miza�onanddevelopment,bio-

pharmaceu�csandanaly�calsciencesaswellasintegrateddrug

discovery and development case histories. The sessions are

designedtobehighlyinterac�ve,andwillincludecasestudiesto

enhancethelearningprocess.Thehighlightofthisprogramwould

be the inclusion of pharmaceu�cal development with the

discoveryvaluechain.Thekeynotelectureswillbepresentedby

Dr.PercyCarter,HeadofDiscoveryandDr.ChristopherSinko,Head

ofPharmaceu�calDevelopmentatBristol-MyersSquibb,USAand

Ms.KiranMazumdarShaw,Chairwoman,Biocon,India.

Wehopethatyou

willjoinusforthis

outstandingcourse

onmedicinal

chemistry and drug

discovery &

development.

Medicinal Chemistry, Drug Discovery

& Development India, 2019 (MCADDI 2019)

in association with

www.mcaddi.com www.bioconacademy.com

Fordetailsoranyqueries,writeto: [email protected] | T: +918067751867/08884899898

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Program Schedule

Monday, March 4th 2019

11:00-18:00

12:00-12:45

12:50-13:00

13:00-15:00

REGISTRATION

LUNCH

WELCOME

Lectures 1 and 2BasicPrinciplesofMedicinalChemistry

Dr. Balu BalasubramanianPharmaInnova�onSourcingCenter,USA

Prof. Thomas Prisinzano,Univ.ofKansas,USA

Tuesday, March 5th, 2019

15:30-16:30

17:15-18:15

18:30-19:30

8:30-9:30

Lecture 3TargetIden�fica�onandValida�on

Lecture 4HitIden�fica�on:High-Throughput/

Phenotypic/Virtual/Fragmentscreening

Lecture 5Hit-to-LeadProcess

Lecture 6LeadOp�miza�on

Dr. Manjunath RamaraoBiocon-BMSR&DCenter,India

Dr. Nagaraj Gowda Glenmark,India

Dr. Manjunath RamaraoBiocon-BMSR&DCenter,India

TEA BREAK16:45-17:15

Dr. Bruce EllsworthBristol-MyersSquibb,USA

SessionChair BaluBalasubramaninan

SessionChair WilliamGreenlee

19:45-20:30 RECEPTION AND DINNER

SessionChair ThomasPrisinzano

Lecture 8SpecialTopic:Applica�onsofFluorinein

DrugDesignandDiscovery

Dr. Nick MeanwellBristol-MyersSquibb,USA

9:45-10:45Lecture 7

DesigningAroundToxicophoresinDrugDiscoveryDr. Nick Meanwell

Bristol-MyersSquibb,USA

11:00-11:30 TEA BREAK

11:30-12:30

12:45-13:45 LUNCH BREAK

SessionChair ThomasPrisinzano

15:00-16:00Lecture 10

G-ProteinCoupledReceptors

13:45-14:45Lecture 9

Enzymes,ReceptorsandIonChannels Dr. Manjunath Ramarao

Biocon-BMSR&DCenter,India

Dr. Bruce EllsworthBristol-MyersSquibb,USA

16:15-16:45 TEA BREAK

Lecture 11Tac�calApplica�onsofBioisosteresinDrugDesign16:45-17:45


Lecture 12Applica�onsofHeterocyclesinDrugDesign18:00-19:00


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Program Schedule

Wednesday, March 6th, 2019

SessionChair:

Thursday, March 7th, 2019

8:30-9:30

9:45-10:45

11:00-11:30

11:30-12:30

WilliamGreenlee

Lecture 18 - Case History:Ruxoli�nib(Jakafi®)forTreatmentofPolycythemiaVeraandMyelofibrosis

Lecture 19 - Case History: Pharmaceu�calDevelopmentaspectsof

Ruxoli�nib(Jakafi®)

TEA BREAK

Lecture 20Introduc�ontoBiologicsBiologicsandBiosimilar

DesignandDevelopment-Part1

LUNCH BREAK

Dr. Narendra Chirmule Biocon,India

Dr. Swamy YeleswaramIncyte,USA


8:30-9:30Lecture 13

LessonsinStructure-BasedDrugDesignDr. Vincent StollAbbVie,USA

9:45-10:45Lecture 14

PrinciplesofMolecularInterac�onsDr. Vincent StollAbbVie,USA

11:00-11:30 TEA BREAK

11:30-12:30Lecture 15

ProteinBinding

12:45-13:45

SessionChair: VincentStoll

Dr. Swamy YeleswaramIncyte,USA13:45-14:45

Lecture 16 DrugMetabolismandPK

15:00-16:00 TEA BREAK/Exhibi�on Hall

Dr. Mukul JainZydus,India16:00-17:30

Lecture 17 - Case HistorySaroglitazar(Lipaglyn®)forTreatmentof

DyslipidemiaandHypertriglyceridemiainTypeII

SessionChair: MukulJain


12:45-13:45 LUNCH BREAK

SessionChair: SwamyYeleswaram

13:45-14:45

Lecture 21IIntroduc�ontoBiologicsBiologicsandBiosimilar

DesignandDevelopment-Part2

Dr. Narendra Chirmule Biocon,India

15:00-16:00Lecture 22

An�body-DrugConjugates(ADCs)Dr. Ni�n Damle

SunPharma,India

16:15-17:00 TEA BREAK/Exhibi�on Hall

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Friday, March 8th, 2019

SudhirKumarSingh-GVKBiosciences,India

Lecture 23GeneralIntroduc�ontoProcessChemistry;Phase-appropriateProcessDevelopment

Lecture 24DrugProductDevelopment-

BasicPrinciples(Pharmaceu�cs&Analy�cal)

Dr. Vaidyanathan RajappaBiocon-BMSR&DCenter,India

Dr. Sridhar DesikanDr.Reddy'sLaboratories,India

SessionChair:

9:45-10:45

8:30-9:30

TEA BREAK11:00–11:30

Program Schedule

Lecture 25CaseHistoryofIntegratedDrugDiscovery

andProcessDevelopment:Part1HIV-1A�achmentInhibitors


LUNCH BREAK

11:30-12:30

12:30-13:30

PravinIyer-GlenmarkPharma,IndiaSessionChair:


andProcessDevelopment:Part2HIV-1A�achmentInhibitors

Dr. Mar�n EastgateBristol-MyersSquibb,USA13:30-14:30

Lecture 27BioPharmaceu�cs–CaseHistory

HIVA�achmentInhibitorsandOthers

Dr. Manish DesaiBristol-MyersSquibb,USA14:45-15:45

Recep�on, Key Note LecturesVenue: Hotel Radha Regent, Electronic City 17:00

BinduAjit,ManjunathRamaRao,VaidyanathanRajappaSessionChairs:

Keynote Lecture-1 CurrentTrendsinIndian

Pharmaceu�calandBiotechnology

Ms. Kiran Mazumdar ShawBiocon,India

17:30-18:00

Keynote Lecture-2FutureTrendsinDrugDiscovery

Dr. Percy CarterBristol-MyersSquibb,USA18:00-18:30

Keynote Lecture-3 Perspec�vesonPharmaceu�calDevelopment

Dr. Christopher SinkoBristol-MyersSquibb,USA18:30-19:00

RECEPTION AND DINNER19:00-22:00

Saturday, March 9th, 2019

VenkataPalle,Lupin,IndiaSessionChair:

Lecture 28IntegratedCaseHistory-ProcessDevelopment

Dr. Vaidyanathan RajappaBiocon-BMSR&DCenter,India

8:30-9:30


andProcessDevelopment:BetaSecretase:PastPresentandFuturePart1

Dr. Jennifer AllenAmgen-USA9:45-10:45


andProcessDevelopment:BetaSecretase:PastPresentandFuturePart2

Dr. Jason TedrowAmgen-USA11:00-12:00

Concluding Remarks12:15PM-12:30 Dr. William Greenlee

LUNCH12:30-1:30PM

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in association with

Accomodation

Lemon Tree Hotel55A,HosurMainRoad,ElectronicsCity,Phase1

Bengaluru560100,Karnataka,India.T:+918044232323

Hotel Name & Contact Details Distance & Travel Time from

Biocon Academy

Amount in INR CP Plus GST

Amount in INR MPAI

3.8Km15Mins

3.9Km15Mins

Single Single Double Double

6,000.00

6,000.00Svenska Design Hotels56-D,ElectronicCity,Bangalore560100,

India.T:+918044310000

7,000.00

7,000.00

8Km25Mins

3,499.00Ibis Bengaluru HosurRoad,26/1,NearCentralSilkBoardJunc�on,

Bommanahalli,Bangalore-560068.T:+918049009090

4,099.00

MPAI -MeansRoom+taxes+BreakfastIncludedPlusonemajormeal(Dinner)attherestaurants

CP -Room+taxes+BreakfastIncluded

*Aqua-ServiceapartmentsonceFlathasthreeBedroomsfullyfurnished

Please note: Pickup/dropoffbetweenthelistedHotelsandBioconAcademywillbearrangedbyMCADDIandthebusschedulewillbeincludedinyourwelcomekit

6Km20Mins

4,000.00Keys Hotels Singasandra,HosurMainRoad,Bengaluru,

Karnataka-560068.T:+918039441000

5,000.00

4Km20mins

5,000.00Radha Regent Bengaluru110CElectronicsCityPhase1,BehindCyberPark

Bengaluru–560100

6,200.00

4Km20mins

5,000.00Radha Regent Bengaluru110CElectronicsCityPhase1,BehindCyberPark

Bengaluru–560100

DID:+918067276842|Tel:+918067276969

Fax:+918067276767

6,200.00

4Km20mins

3,000.00Sai Vishram144/C1,KirloskarRoad,BommasandraIndustrialArea,

Hebbagodi,Bangalore-560099.

T+918040400400/22634000(Vegetarian Hotel)

3,750.00

3Kms15Mins

1,850.00[with

Breakfast]

Guesture Social Life Spaces (ShandersAltaVistaApartment),

Veerasandra,ElectronicCityPhase1

Bangalore–560100

Mr.Kariappa–7899932092,[email protected]

Mr.Nanjappa–9844524841,[email protected]

2,500.00[with

Breakfast]

2,000.00[with

Breakfastand

Dinner]

2,800.00[with

Breakfastand

Dinner]



in association with


Registration

MCADDI Course Registration Fee

INDUSTRIAL DELEGATE

OnorBeforeFeb 03, 2019

NetAmount-INR 25,000 +Tax

A�erFeb 04, 2019

NetAmount-INR 27,000 +Tax

OnorBeforeFeb 03, 2019

NetAmount-INR 10,000 + Tax

A�erFeb 04, 2019

NetAmount-INR 11,000 + Tax

ACADEMIC/STUDENT DELEGATE

REGISTRATIONS NOW OPEN!

Par�cipants can send the payment forMCADDI 2019 either by DD drawn in favour of Biocon AcademypayableatBangaloreORcandoaNEFTtothefollowing:

How to Register

Beneficiary Name

IFSC code

Beneficiary Bank

Beneficiary A/c No

:BioconACADEMY

:HDFC0000523

:HDFCBANKLIMITED,8/24,SalcoCentre,RichmondRoad,Bangalore–560025

:05230310003152

• Applicantscandownloadtheregistra�onformfromthewebsitewww.mcaddi2019.comand senddulyfilledformanddemandDra�orconfirma�onoftheNEFTTransferto:Biocon Academy, Biocon House, Semicon Park, Electronic City, Phase II, Hosur Road, Bangalore - 560100, India

• Applica�onswillbeconsideredonfirstcomefirstservebasis.Thedeadlineforearlyregistra�onis February 03rd, 2019

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Dr. Venkat Palle

Dr. Sudhir Kumar Singh

Dr. Arvind Mathur

Dr. Manjunath Rama Rao

Ms. Bindu Ajit

Mr. S.S. Easwaran

Advisory Board

Dr. Balu N. Balasubramanian

Dr. William Greenlee

Mr. M. B. Chinappa

-PharmaInnova�onSourcingCenter,LLC,USA

-MedChemDiscoveryConsul�ng,LLC,USA

-SyngeneInterna�onal,India

Organizing Committee

-LupinPharma,India

-GVKBiosciences

-Bristol-MyersSquibb,USA

-BioconBristol-MyersSquibbR&DCenter,India

-BioconAcademy,India

-BioconAcademy,India

in association with


About Biocon Academy

BioconAcademy-CenterofExcellenceforAdvancedLearninginAppliedBioscienceswasintroducedasaCSRIni�a�veofBioconwithacommitmenttocreateagloballycompe��veBiotechecosysteminIndiathroughskilldevelopment.

BioconAcademyleveragesrichindustryexperienceofBioconandsubjectexper�seofinterna�onalEduca�onPartners,suchasKeckGraduateIns�tute,California,USAandBITSPilani,Indiatodeliverindustry-orientedtrainingprogramstobiotechstudents.TheProgramsofferedhereaimtoempowertheBiotechnologyandengineering graduates with advanced learning and industrial proficiency through job-skills developmentessen�altobuildapromisingcareerintheBiotechindustry.

Fordetailsoranyqueries,writeto: [email protected] | T: +918067751867/08884899898Biocon Academy, BioconHouse,SemiconPark,ElectronicCity,PhaseII,HosurRoad,Bengaluru,Karnataka560100

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Glimpses of MCCADI 2017


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Documents

Medicinal Chemistry And Drug Discovery & Development India ...mcaddi.com/images/Brochure_MCADDI_2019.pdf · Electronic City, Phase II, Hosur Road, Bengaluru, Karnataka 560100 Date: