Managementul Depresiei in Medicina Primara

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    A Guide to Best Practice

    Primary Care Services

    or Depression

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    DH INFORMATION READER BOX

    Policy

    HR/ Workforce

    Management

    PlanningClinical

    Estates

    Performance

    IM & T

    FinancePartnership Working

    Document Purpose Best Practice Guidance

    ROCR Ref: Gateway Ref: 6996

    Title Primary Care Servise for Depression -

    A Guide to Best Practice

    Author Care Services Improvement Partnership (CSIP) / NPCRDC

    Publication Date 01 September 2006

    Target Audience GPs, PCT Mental Health Commissioners

    Circulation List GPs, PCT Mental Health Commissioners

    Description Changing the way care for depression is delivered is

    complex. The precise issues will vary from place to place

    reectinglocalcircumstances.Thechallengeremainsfor

    primary care commissioners to engage GPs and their

    practices in the development of mental health care. It is

    hoped that this guidance document and the incentives in

    the Quality and Outcomes Framework are mechanisms to

    assist in achieving this goal.

    Cross Ref N/A

    Superseded Docs N/A

    Action Required N/A

    Timing N/A

    Contact Details Emma Sarno

    Care Services Improvement Partnership

    North West Development Centre

    Hyde Hospital, 2nd Floor, Hyde, Cheshire

    SK14 5NY

    0161 351 4920

    www.csip.org.uk

    For Recipients

    AUTHORS

    Janine Fletcher

    Department o Nursing, University o Manchester

    Peter Bower

    NPCRDC, University o Manchester

    Linda Gask

    NPCRDC, University o Manchester

    David Richards

    Department o Health Sciences, University o York

    Tim Saunders

    NIMHE North West

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    CONTENTS

    EXECUTIVE SUMMARY Page 4

    CHAPTER 1: Introduction Page 5CHAPTER 2: Depression In Primary Care Current Issues And The Latest Evidence Page 6

    CHAPTER 3: Assessment O The Presence And Severity O Depression Page 9

    CHAPTER 4: Clinical Pathways Page 11

    CHAPTER 5: Monitoring And Follow Up Page 16

    CHAPTER 6: Patient Preernce And Choice Page 21

    CHAPTER 7: Roles For Proessionals Page 22

    CHAPTER 8: Interace Issues Page 23

    CHAPTER 9: Case Studies Page 24

    CHAPTER 10: Audit And Monitoring Page 26

    APPENDICES

    Appendix 1: Screening For Depression In High Risk Groups Page 26

    Appendix 2: Assessing The Severity O Depression (Icd-10 Primary Care Version) Page 27

    Appendix 3: Other Scales For The Assessment O Severity And Outcome Page 28

    Appendix 4: Asking About Risk Page 28

    Appendix 5: Asking About Alcohol Problems The Cage Questionnaire Page 29

    Appendix 6: Audit Questionnaire: Screening For Alcohol Misuse Page 30

    Appendix 7: Relevant Patient Inormation Resources Page 32

    Appendix 8: Treatments At Step 2 Page 32

    Appendix 8: Websites With Inormation On The Collaborative Care Page 34

    And Case Management Approach

    Appendix 10: Phq-9 Monitoring Tool Pfer Page 34

    Appendix 11: Recommended Categories For Response And Monitoring With The Phq-9 Page 36

    REFERENCES Page 37USEFUL RESOURCES

    Books and Reports Page 39

    Organisations and Websites Page 41

    Primary Care Services

    or Depression

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    EXECUTIVE SUMMARY

    Depression is highly prevalent in primary care, and

    a major cause o disease burden. The prognosis o

    many depressive disorders is poor, and rates o relapse

    and recurrence are high.

    Given the burden associated with depression, it is

    crucial that the care provided in primary care is o the

    highest quality. However, management o depression in

    primary care is not always optimal.

    There are a number o key issues that are increasingly

    important to the delivery o primary care services or

    managing depression.

    Improving access to psychological therapies-

    Research has indicated that psychological therapy

    is both eective and popular with patients1,1,

    but all services have problems with access. Lord

    Layard has made a case or increased provision o

    psychological therapies (especially CBT) rom an

    economic perspective.

    Improving access to psychological therapies

    minimal interventions and sel help - Minimalinterventions are treatments that require less input

    rom a proessional therapist compared to traditional

    psychological therapy (also called sel help). These

    interventions are usually based on books, computer

    programmes or websites, and oten ocus on teaching

    CBT techniques.

    Stepped care - There are two key eatures o a

    stepped care system: (a) the recommended treatment

    should be the least intensive o those currentlyavailable, but still likely to provide signicant health

    gain (b) the results o treatments are monitored

    systematically, and changes are made (so-called

    stepping up) i current treatments are not achieving

    signicant health gain.

    Depression as a chronic disease - Traditionally,

    primary care services have been structured around

    acute care. However, depression may be better viewed

    as a chronic disease, characterised by high levels o

    relapse and recurrence. This means that depression

    may be best treated through the use o specic chronic

    disease management models.

    A population perspective on depression -

    Population-based care is aimed at restructuring

    service delivery to provide a strategy or care or all

    patients within a dened population with a recurrent

    or chronic illness.

    Collaborative care and case management-

    Research has indicated that an eective method

    o improving depression outcomes is collaborative

    care. This involves GPs and mental health specialists

    working more closely to supervise the ongoing care o

    depressed patients.

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    CHAPTER 1: INTRODUCTION

    Since the original version o this guidance document

    was published in 00, a number o important

    developments have taken place in the commissioning

    and implementation o mental health services.

    The new GP contract has had a signicant impact on

    the way primary care services are delivered. The recent

    additions to the Quality and Outcomes Framework

    ocussing on depression include two new indicators

    which encourage primary care to screen or depression

    in high risk groups, namely diabetes and coronary

    heart disease, and monitor the severity o depression in

    patients with a new diagnosis.

    Implementation o NICE guidelines and the incentives

    in the Quality and Outcomes Framework is likely to lead

    to signicant improvements in the management and

    treatment o depression in primary care.

    However, challenges lie ahead or both primary care

    and mental health commissioners in overcoming

    problems with current service delivery. These

    challenges include improving access to a range

    o psychological therapies in primary care and astrengthening o the primary-secondary care interace.

    There are also opportunities around the redesign o

    existing services such as community mental health

    teams and counselling services, and the introduction o

    new workers such as the graduate primary care mental

    health workers and practitioners with a special interest.

    This will require mental health commissioners to

    develop improved access to a range o psychological

    therapies in primary care, to mental health assessment

    (where required), and a strengthening o the primary/

    secondary care interace. There are also opportunities

    around the redesign o existing services such as

    community mental health teams and counselling

    services, and the introduction o new workers such as

    the graduate primary care mental health workers andpractitioners with a special interest.

    There has been a call or a signicant increase in the

    number o psychological therapists to deliver evidence

    based interventions.1 Whilst this idea is supported

    in principle, initial recommendations are likely to

    take some time to be achieved. It is possible that a

    signicant amount o primary care provision can be

    supported by proessionals other than those with

    specialist psychological therapy skills.

    So ar the implementation o graduate primary care

    mental health workers across the country has been

    patchy and in some areas the opportunities have not

    been realised. In areas where implementation has

    been supported by local training programmes and

    management structures, services are recognising the

    benets o this new workorce. These new workers

    are key to the delivery o the stepped care model and

    proper career structures or this group o workers are a

    matter o urgency.

    Changing the way care or depression is delivered is

    complex. The precise issues will vary rom place to

    place refecting local circumstances. The challenge

    remains or primary care commissioners to engage

    GPs and their practices in the development o mental

    health care. It is hoped that this best practice guidance

    document and the incentives in the Quality and

    Outcomes Framework are mechanisms to assist in

    achieving this goal.

    Primary Care Services

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    CHAPTER 2: DEPRESSION IN PRIMARYCARE CURRENT ISSUES AND THELATEST EVIDENCE

    Depression is highly prevalent in primary care, and a

    major cause o disease burden. The prognosis o many

    depressive disorders is poor, and rates o relapse and

    recurrence are high.

    Given the burden associated with depression, it is crucial

    that the care provided in primary care is o the highest

    quality. However, management o depression in primary

    care is not always optimal, with concerns about a ailure

    to recognise depressive disorders, to provide medication

    in line with current guidelines, and an inability to provide

    access to psychological treatments. These problems

    refect pressures on proessional time, training and

    resources.-

    The original eorts to overcome these problems through

    initiatives such as the Deeat Depression campaign7 and

    practice-based education8 had some success, but the

    impact o these initiatives has been relatively modest.

    In part, this refects the complexities associated with

    the management o depression, and the many actors

    that interact to reduce the quality o care in primary

    care. There are no magic bullets, and improving the

    quality o care or depression requires changes to

    the way care is provided and additional resources to

    develop the appropriate systems to enable primary care

    proessionals to deliver high quality care.,9-11

    Previous research on the management o depression in

    primary care has tended to be critical in tone. However,

    it is important to note that many GPs and primary care

    teams have developed ways o managing depression

    that are eective and valued by patients. The models

    have been developed over time and are sensitive to

    the particular nature o primary care and its role in

    patients lives. However, the enthusiasm o primary care

    proessionals or mental health work varies signicantly,

    which means that good quality care is not always

    available to all patients.

    The models o care presented here are designed to build

    on present good practice in primary care and refect the

    current evidence base. The main innovations relate to

    the standardised assessment o depression in primary

    care, and the systematic organisation o care that

    ollows rom that assessment.

    Key issues rom the latest research

    There are a number o key issues that are increasingly

    important to the delivery o primary care services or

    managing depression. Some relate to issues about

    service structure, while others concern the particular

    types o interventions that should be delivered.

    Improving access to psychological

    therapies the Layard approach

    Research has indicated that psychological therapy

    is both eective or depression1 and popular with

    patients.1 However, almost all services have problems

    with access, with long waiting lists resulting rom limited

    numbers o trained therapists. This leads to rustration

    or patients, primary care proessionals and therapists.

    Lord Layard has made a case or increased provision

    o psychological therapies (especially CBT) rom an

    economic perspective.1 He argues that employment

    and mental health may be linked as both cause and

    consequence. Mental health problems account or

    a signicant number o days lost rom work and a

    signicant proportion o patients on incapacity benets.

    I the accessibility and eectiveness o psychological

    therapy can be translated into increased return to work,

    then additional therapists can be employed on the basis

    that the overall costs to society can be recouped.

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    7

    Improving access to psychological therapies

    minimal interventions and sel help

    Although increases in the number o therapists will go

    some way towards bridging the gap between supply

    and demand, it is unlikely to provide a complete

    solution because o the high prevalence o depressive

    problems in the community.

    An alternative approach to getting more benet rom

    current resources is to ocus on the delivery o minimal

    interventions to a proportion o depressed patients.

    The term minimal intervention reers to the act that

    these treatments require less input rom a proessional

    therapist compared to traditional psychological therapy.

    Much o the ocus on minimal interventions concerns

    sel help. Sel help interventions are usually based on

    books, computer programmes or websites, and oten

    ocus on teaching CBT techniques to patients to help

    them manage their symptoms. There is encouraging

    evidence that such approaches are eective in the

    management o depressive disorders.1 Because

    these treatments are generally not dependent on the

    availability o a specialist psychological therapist, theyprovide one method o overcoming problems with

    access.1

    Although sel-help is oten based on health

    technologies such as books, computer programmes

    and websites, the National Institute o Clinical

    Excellence (NICE) recommends the adoption o a

    guided sel-help model with some limited therapist

    contact. The guidance states:

    For patients with mild depression, consider a

    guided sel-help programme that consists o the

    provision o appropriate written materials and limited

    support over to 9 weeks, including ollow up, rom

    a proessional who typically introduces the sel-help

    programme and reviews progress and outcome.

    Although NICE has highlighted this model, other

    minimal interventions which may be o use are

    computerised cognitive behaviour therapy,1

    signposting 17 or group psychoeducation.18 All could

    provide more ecient delivery o care, meaning more

    patients can access eective treatment.

    Stepped care

    Stepped care links conventional psychological therapy

    with minimal interventions in a system designed to

    provide the greatest amount o benet rom current

    resources. Stepped care is a model o healthcare

    delivery with its origins in the US, which has been

    applied to a range o disorders, particularly those o a

    chronic nature.19-1

    There are two key eatures o a stepped care system.

    Firstly, the recommended treatment should be the

    least intensive o those currently available, but still

    likely to provide signicant health gain. In stepped

    care, more intensive treatments are reserved or

    patients who do not benet rom less intensive rst

    line treatments.

    Secondly, stepped care is sel-correcting, in that the

    results o treatments and decisions about treatment

    provision are monitored systematically, and changes

    are made (so-called stepping up) i current

    treatments are not achieving signicant health gain

    or an individual patient.

    This is similar to the way many clinicians implicitly

    operate, but stepped care standardises systems

    and procedures with an explicit aim o improving

    eectiveness and eciency.

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    8

    Depression as a chronic disease

    Traditionally, primary care services have been

    structured around acute care. However, studies

    o the natural history o depression have indicated

    that depression may be better viewed as a chronic

    disease, characterised by high levels o relapse and

    recurrence. This means that depression may be best

    treated through the use o specic chronic disease

    management models, similar to the models adopted

    in relation to other chronic diseases like asthma and

    diabetes.

    A population perspective on depression

    Taking the chronic disease management perspective

    on depression means that primary care organisations

    will have to shit their perspective on depression rom

    the care o the individual patient, to the care o the

    entire population o depressed individuals. Population-

    based care is aimed at restructuring service delivery

    to provide a strategy or care or all patients within a

    dened population with a recurrent or chronic illness.

    Collaborative care and case management

    Research has indicated that an eective method

    o improving depression outcomes is collaborative

    care. This involves GPs and mental health specialists

    working more closely to supervise the ongoing

    care o depressed patients. GPs are responsible or

    recognition o the disorder, antidepressant prescription

    and overall co-ordination o care, while the mental

    health specialist (such as a psychiatrist) provides expert

    consultation, support and advice. However, the most

    signicant dierence associated with collaborativecare models is the introduction o a case manager.

    The case manager takes responsibility or ollowing

    up patients proactively, assessing patient adherence

    to psychological and pharmacological treatments,

    monitoring progress, taking action when treatment is

    unsuccessul, and delivering psychological support

    Case managers may be thought o as physician

    extenders, who work under the supervision o the GP

    to improve quality o care or patients with depression.

    They do not work alone, but receive support rom a

    specialist proessional, and share inormation with the

    GP. A variety o proessionals may be able to take up

    the case management role, including practice nurses,

    mental health nurses, and the new graduate primary

    care mental health workers.

    Although the vast bulk o case managementinterventions have been tested in the United

    States, two recent evaluations in England have also

    demonstrated very positive results.

    Summary

    The previous section raised key issues in current

    models o depression care. These themes have

    inormed the model o care highlighted in this

    commissioning guide, which can be discussed in

    terms o three key aspects o care: assessment; clinicalpathways; and monitoring (Figure 1, overlea).

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    9

    Initial assessment

    Severity o depression, risk and other important

    actors are systematically assessed

    Treatment decision making is based on the results o

    that assessment and patient preerences

    All patients are provided with high quality inormation

    about depression, its treatment, and local services

    Figure 1 Overview o the model

    Clinical pathways

    The clinical pathway consists o a number o steps.

    Patients enter at dierent steps, depending on

    severity and previous history

    Many patients will enter the pathway at the rst or

    second step, and will access higher steps in order, i

    there is a lack o progress

    Within steps, there are choices or patients about the

    type o treatment that suits them best

    Monitoring and ollow up

    Each patient should have a planned schedule o

    contacts to assess progress. The exact schedule

    depends on severity and other actors

    Scheduled contacts use objective outcome

    measures as a marker o progress and an aid to

    clinical decision making

    Decisions may involve changes o treatments withinsteps, or moving patients up to new steps

    CHAPTER 3: ASSESSMENT OF THEPRESENCE AND SEVERITY OF DEPRESSION

    Screening

    The psychological and social situation o some patients

    makes them very vulnerable to depression. In these cases,

    primary care proessionals may need to proactively screen

    or symptoms o depression. NICE recommends primary

    care routinely screens certain high risk groups:

    Patients with signicant physical illness

    Patients with other mental health problems, such as

    dementia

    Patients suering major lie events, such as childbirth,

    long-term or recent unemployment and bereavement

    Patients with a history o relationship diculties and

    physical, sexual or emotional abuse

    The new Quality and Outcomes Framework has now

    incentivised screening in patients on the diabetes or

    coronary heart disease register.

    DEP1: The percentage o patients on the diabetes registerand /or the coronary heart disease register or whom

    case nding or depression has been undertaken on

    one occasion during the previous 1 months using two

    standard screening questions.

    Appendix 1 shows recommended questions or use in

    screening or possible cases o depression.

    Assessment

    Depression is a sensitive and stigmatised subject and

    there is no replacement or eective communication skills

    to encourage the presentation o depression within the

    consultation.

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    10

    However, idiosyncratic and unstructured approaches to

    the assessment o depression may mean that patients are

    oered the wrong treatment. I depression is suspected,

    a more comprehensive assessment must be conducted.This may be most appropriately done by the GP, but

    could be completed by a variety o appropriately trained

    health proessionals. This assessment should involve

    standardised measures o:

    Severity o depression

    Risk

    Other relevant psychosocial actors

    Ruling out o other causes (i.e. testing thyroid unction)

    Severity

    The new Quality and Outcomes Framework has now

    incentivised the assessment o depression using a

    validated assessment tool.

    DEP: In those patients with a new diagnosis o

    depression, recorded between the preceding 1 April to

    1 March, the percentage o patients who have had an

    assessment o severity at the outset o treatment using anassessment tool validated or use in primary care.

    A number o dierent methods can be used to categorise

    the severity o depression. Appendix details an

    assessment o the severity o depression according to the

    ICD-10 checklist. NICE recommends the categorisation o

    patients by mild, moderate or severe levels o depression,

    so as to guide clinical decision making. A categorisation tool

    such as the ICD-10 can help. Other instruments may be o

    use, and some alternatives are provided in Appendix .

    Although the Quality and Outcomes Framework provides

    incentives or assessment o severity at the outset o

    treatment, it is recommended that measures be used to

    assess the outcome o treatment and assist in decisions

    about urther management. This will be discussed later in

    the guide.

    Such instruments are acceptable to patients i they are

    sensitively introduced with a clear explanation o the

    purpose o the task e.g. Would you mind taking a couple

    o minutes to complete this orm - itll help us to decide

    what is the best orm o help or how you are eeling (or to

    show us how you have been progressing). Patients may

    also nd the questionnaire useul or explaining to relatives

    how they have been eeling.

    Risk

    Suicidal thoughts are very common in depression.

    Patients with depression should always be asked directly

    about suicidal thoughts and intent. Possible questions to

    ask when assessing risk are included in Appendix .

    There is a training package available or primary care and

    mental health sta in the assessment and management

    o suicide risk: Skills-based Training On Risk Management

    (STORM). This package uses the train the trainers ormat

    and can be commissioned by Trusts or dissemination to

    all stawww.medicine.manchester.ac.uk/storm/

    Other relevant actors

    The assessment should also include questions relating to:

    Previous mental health problems including treatment

    and outcome

    Family history o mental health problems

    Associated disability

    Availability o social support

    Social problems (amily disputes, nancial,employment)

    Alcohol (see Appendix and ) and drug use

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    11

    Patient education

    The results o any assessment will need to be ed

    back to patients sensitively. There is still a signicant

    stigma associated with depression, and patients may

    be initially unwilling to accept the diagnosis, and may

    not want to start or to continue treatment. This means

    there is a need or discussion with the patient about

    diagnosis and treatment options, with a view to gaining

    agreement about the treatment plan.

    This will involve:

    Feedback to the patient on the outcome o the

    assessment

    Providing patient inormation leafets about

    depression, its treatment, useul management

    strategies (such as liestyle changes diet,

    exercise, sleep hygiene) and local services (see

    Appendix 7 or relevant resources)

    Discussing treatment options. The initial ocus

    o these discussions will concern whether an

    intervention is required or not. Patients who do

    not require or do not want an intervention will be

    invited back or a review with the GP in weeks.

    Patients who do require an intervention will enter

    the model at an appropriate step based on their

    clinical need. This is explained in more detail in the

    next section

    CHAPTER 4: CLINICAL PATHWAYS

    Key messages

    The clinical pathway is represented by a number

    o steps. Each step denes a certain type and

    intensity o treatment. Patients may enter the

    clinical pathway at dierent steps depending on

    their initial presentation or previous history, and

    may be stepped up at various points during the

    course o their illness, depending on progress

    Many patients will enter the pathway at the rst

    or second step, and may access higher steps in

    order, depending on clinical need

    Within steps, there are some choices patients

    can make about the type o treatment that suits

    them best

    As noted earlier, primary care organisations need to

    develop ways o managing depression that provide the

    greatest benet to their population.

    Although the Layard initiative has the potential to

    increase the number o psychological therapists, this

    potential may not be realised or some time. Thereore,

    it is likely that the introduction o sel help and other

    minimal interventions within a stepped care system will

    be a key driver o increases in the abilities o services to

    meet demand.

    The key idea underpinning stepped care is that patients

    receive the least intensive intervention that is still

    expected to provide signicant benet to their health.

    Figure shows the basic stepped care model, and

    shows how it diers rom traditional services.

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    1

    Figure has the more detailed stepped care model

    based broadly on that proposed by NICE. There

    are a number o important issues to note. First, the

    main ocus or primary care is steps 1-, with step

    requiring interace between primary care and specialist

    services. Secondly, step 1 is or patients who do not

    require or want a specic intervention. The other steps

    are or increasing levels o symptoms, distress and

    problem complexity. It may be appropriate or patients

    to bypass previous steps i their symptoms are severe

    enough, or i they had previously tried a step, but did

    not benet. However, some patients may start at the

    lower steps and access higher ones only i they do not

    benet rom their initial treatment.

    Although the model involves steps, it could be

    argued that the main innovation is the introduction

    o step . The greatest benet may be gained rom

    stepped care i a signicant proportion o patientsare successully managed at step . Thereore, some

    services may wish to use step as a deault or

    mild to moderate depression in primary care, with

    specic exceptions (e.g. severe depression, suicidal

    ideation or other indicators o severe problems). Other

    services may restrict step to patients with relatively

    mild depression, and direct patients with moderate

    disorders to step immediately.

    The exact model adopted is likely to depend on the

    available resources. Nevertheless, it should be noted

    that one key advantage o stepped care is that patients

    who do not benet rom less intensive interventions

    at step are identied and encouraged to try other

    treatments, because they are systematically assessed

    ater their treatment.

    Stepped care is an innovative method o organising

    services, and there are a number o complex issues

    where guidance has yet to be provided. For example,

    how much o the available resources should be placedat step ? How should decisions be made about which

    step patients access initially? What sort o patients

    might miss out lower steps?

    The Service Delivery and Organisation (SDO) unding

    body o the NHS has commissioned research on

    these issues which will seek to provide more specic

    guidance in the near uture.

    Figure 2 The basic stepped care model

    Primary Care Primary Care

    Minimal

    interventions

    Specialist

    Interventions

    Specialist

    Interventions

    Traditional Models Stepped Care

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    1

    Treatments in the stepped care system

    The main treatments which are recommended or

    dierent categories o depression severity are detailed

    briefy below (urther details o these treatments

    are provided in Appendix 8). Some o these

    recommendations are rom NICE guidance and other

    reviews o evidence. It is not expected that all services

    will necessarily have all the proposed treatments

    available. Rather, this list should serve as a guide to

    possible interventions.

    Step 1

    Watchul waiting. According to NICE, watchulwaiting can be used with (a) patients who do not

    wish to have an intervention (b) patients who the

    health proessional thinks will recover without an

    intervention

    Step 2

    Guided sel-help. This involves a CBT-based sel-

    help resource and limited support rom a health

    care proessional

    Computerised CBT, based on the recent

    recommendations rom NICE

    Group psycho-education. This involves a group

    treatment, providing inormation about depression,

    and strategies or managing it

    Exercise on prescription. Being physically active

    can assist in the recovery o depression. Exercise

    on prescription schemes establish links withlocal leisure centres to allow patients to access

    equipment and receive regular advice and

    monitoring rom qualied proessionals

    Signposting or reerral acilitation. This involves

    assessing a patient and assisting them to

    nd appropriate local or national voluntaryorganisations

    Antidepressants are not generally recommended

    or patients with mild depression because the

    risk/benet ratio is poor. Medication is more

    commonly used with patients at steps and

    above. Exceptions may be made when patients

    have ailed to benet rom other interventions at

    lower steps, or where patients have a previous

    history o moderate to severe depression

    Step 3

    Brie psychological therapy. There are a number o

    relevant psychological therapies, including CBT and

    counselling. The recommended treatment is -8

    sessions over 10-1 weeks

    Medication. According to the NICE guidelines, there is

    more evidence or the eectiveness o antidepressant

    medication in moderate to severe depressionthan in mild depression. In moderate depression,

    antidepressant medication should be routinely oered

    to all patients beore psychological interventions.

    Careul monitoring o symptoms, side eects and

    suicide risk (particularly in those aged under 0) should

    be routinely undertaken, especially when initiating

    antidepressant medication. Patient preerence and

    past experience o treatment, and particular patient

    characteristics should inorm the choice o drug. It

    is also important to monitor patients or relapse anddiscontinuation/withdrawal symptoms when reducing

    or stopping medication. Patients should be warned

    about the risks o reducing or stopping medication

    Primary Care Services

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    1

    Collaborative care and depression case

    management. Although the prescription o

    medication as recommended by NICE can be

    conducted by the GP alone, it is likely that the

    eectiveness and acceptability o the approach

    will be enhanced through the addition o case

    management through a collaborative care

    approach. The key acets o such an approach are

    as ollows:

    Assigning a case manager to a patient, who

    is supported by a specialist mental health

    proessional, and collaborates with the GP in

    the care o the patient

    Provision o medication and/or brie

    psychosocial interventions

    Proactive management o the patient led by the

    case manager, including regular ollow up (ace

    to ace contact, or by phone), and monitoring o

    progress

    Feedback o inormation about treatment and

    progress rom the case manager to the GP and

    mental health specialist to assist in treatment

    decision making in patients who ail to improve

    Most o the published studies using depression

    case management have involved medication,

    and it is expected that a signicant proportion

    o patients at this step will be on medication.

    However, all patients will receive additional

    psychosocial support rom the case manager, and

    it is possible or the case management approach

    to be used with psychosocial interventions alone,

    i patients do not wish to use medication. For

    example, a patient with a moderate depression

    who does not wish to take medication may

    receive case management, with psychosocial

    support oered in the orm o acilitated sel-help

    or signposting to other services, as appropriate

    Appendix 9 details a number o websites with

    relevant resources or use in the collaborative care

    approach

    Step 4

    Psychological therapy. The treatment o choice is

    CBT o longer duration (1-0 sessions over -9

    months), although in some cases interpersonal

    therapy may be used

    Medication, collaborative care and depression

    case management are again relevant with this

    group o patients

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    1

    Chronic, atypical

    reractory, recurrent

    Severe depression

    Moderate depression

    Mild to moderate

    depression

    Sub-clinical and

    patients who choose

    not to have intervention

    Step 1

    Watchul waiting

    Step 2

    Guided sel-help, exercise on prescription,

    psycho-education, signposting, or computerised CBT

    Step 3

    Medication, case management and collaborative

    care, psychological therapy

    Step 4

    Medication, case management and

    collaborative care, psychological therapy

    Step 5

    Specialist services

    ASSESSMENT

    Figure Overview o the stepped care system

    Primary Care Services

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    1

    CHAPTER 5: MONITORINGAND FOLLOW UP

    Key messages

    All patients treated or depression should have a

    planned schedule o contacts in order to assess

    response to treatment and ongoing progress.

    The exact schedule will depend on the severity o

    depression and other relevant actors

    Scheduled contacts should include the use o

    objective outcome measures as a marker o

    progress and an aid to clinical decision making

    Decisions may involve change o treatment within

    steps, or moving patients up to new steps i they

    have ailed to progress

    Phases in depression treatment

    At a broad level, depression can be thought o as

    having three phases:

    Acute phase the aim o treatment is reducing

    symptoms and achieving remission (approximately8-1 weeks i treatment is successul)

    Continuation phase the aim is prevention o

    the return o symptoms during the current period

    (approximately months rom the end o the

    acute phase)

    Maintenance the aim is prevention o new

    episodes o depression (approximately months

    rom the end o the continuation phase)

    The model recommends regular, proactive contact with

    patients throughout these phases. The schedule will

    depend on the severity o the problem, and the phase.

    Figures - shows some suggested schedules ocontacts or patients at the dierent steps.

    Monitoring response in acute

    phase treatment

    The goal o acute phase treatment is remission o

    symptoms. The denition o remission will depend on

    the assessment instruments used. A variety o tools

    are available. In Appendix 10 there is a copy o a

    questionnaire rom the United States called the PHQ-

    9 which can be used reely. Appendix 11 includes

    denitions o initial response to treatment and remission

    which can be used in urther clinical decision making.

    The Clinical Outcome in Routine Evaluation outcome

    measure (CORE-OM) is oten used in primary care

    in the UK, and may be another useul measure o

    progress. Whatever instrument is used, it is important

    that there are appropriate and agreed systems or

    dening response to treatment and remission, similar to

    those in Appendix 11.

    Monitoring response may be undertaken by the

    GP (e.g. during watchul waiting) or another health

    proessional (e.g. practice nurse, graduate primary

    care mental health worker, primary care mental health

    proessional or a counsellor). In some cases, the

    proessional providing the treatment may dier rom the

    person monitoring progress. In all cases, inormation is

    shared with the GP.

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    17

    Decision making about acute

    phase treatment

    The result o the assessment o response to acute

    phase treatment eeds into decision making about

    urther care. As the goal is remission, patients who

    improve, but do not remit, and those who do not

    improve will need their treatment reviewing. Patients

    who improve, but do not remit, may simply need

    more time on the same treatment. However, patients

    who ail to benet at all may be more likely to need an

    alternative treatment within a step, or stepping up (see

    Figures -).

    Periodic monitoring in the continuationand maintenance phases (Steps 3/4 only)

    Patients with moderate and severe depression require

    longer term monitoring. Some patients who achieve

    remission may relapse, while others may have a

    recurrent episode. Following remission and during the

    continuation and maintenance phases, patients should

    be proactively ollowed-up in order to monitor

    their status.

    Figures - summarise the structure o care at each o

    the initial steps, and detail:

    The initial treatment

    The proposed schedule o contacts involved in the

    initial treatment, plus appropriate proessionals to

    deliver this treatment

    The suggested point at which patient progress

    during the acute phase is reviewed, together with

    the appropriate proessional to conduct the review

    The possible decisions to be made on the basis

    o the progress review, and which proessionals

    might be involved in the decision making

    The proposed schedule o contacts involved in

    the maintenance and continuation phases (where

    appropriate)

    The suggested point at which longer term

    patient progress is reviewed, together with the

    appropriate proessional to conduct the review

    The exact nature o each step, the proessionals

    involved and the treatments provided will depend

    on local resources and current service structure.

    Primary Care Services

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    18

    Initial treatment Sessions in

    acute phase

    Progress review Decision making

    ollowing review

    Treatment contacts

    in maintenance and

    continuation phase

    Long term review

    Watchul

    waitingNone

    2 weeks

    GP

    I improved

    or remitted

    no urther

    intervention

    I not

    improved

    step upFigure - Clinical pathway or step 1

    Initial treatment Sessions in

    acute phase

    Progress review Decision making

    ollowing review

    Treatment contacts

    in maintenance and

    continuation phase

    Long term review

    Guided

    sel-help

    CCBT

    Exercise on

    prescription

    Signposting

    2-3

    sessions

    (GW/PN)

    Varies

    depending

    on program

    Reerral to

    appropriate

    scheme

    1-2

    sessions(GW/PN)

    8 weeks

    GW/PN

    I improved

    more o initial

    treatmentor another

    treatment within

    step, inorm GP

    I remitted

    inorm GP,

    discharge

    I not

    improved

    another

    treatment within

    step or step up,

    inorm GP

    Figure - Clinical pathway or step

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    19

    Initial treatment Sessions in

    acute phase

    Progress review Decision making

    ollowing review

    Treatment contacts

    in maintenance and

    continuation phase

    Long term review

    Brie therapy

    Medication

    with case

    management

    6-8 weekly

    sessions

    (Therapist)

    6 ortnightly

    monitoring

    sessions

    (GW/PN)

    12 weeks

    GW/PN

    I improved

    more o initial

    treatment or

    another treatment

    within step, inorm

    GP

    I remitted

    inorm GP,

    I not improved

    Discuss with GP

    or therapist

    another treatment

    within step, OR

    step up, inorm

    GP

    Figure - Clinical pathway or step Step 4

    Every 2

    months

    or 12

    months

    GW/PN

    6 and 12

    months

    GW/PN

    Primary Care Services

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    0

    Initial treatment Sessions in

    acute phase

    Progress review Decision making

    ollowing review

    Treatment contacts

    in maintenance and

    continuation phase

    Long term review

    Figure - Clinical pathway or step

    Medication

    and case

    management

    CBT/IPT

    12 weekly

    sessions

    (Gateway,

    PwSI, CPN)

    16-20

    weekly

    sessions

    (Therapist)

    24 weeks

    (Experienced

    GW, Gateway,PwSI, CPN)

    I improved

    more o initial

    treatment or

    another treatment

    within step, inorm

    GP

    I remitted

    inorm GP,

    I not improved

    Discuss with GP

    or therapist

    another treatment

    within step, OR

    step up, inorm

    GP

    Every

    month or

    12 months

    (Gateway,

    PwSI, CPN)

    6 and 12

    months

    (Gateway,

    PwSI, CPN)

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    1

    CHAPTER 6: PATIENTPREFERENCE AND CHOICE

    One issue that is oten raised about standardised

    systems o care is that they take little account o the

    preerences, needs and wishes o individual patients.

    Primary care has long prided itsel on being ocussed

    on exactly these issues.

    However, there is room or patient choice within the

    proposed model.

    Patients may make choices within steps. For example,

    when patients enter step , they may choose rom a

    number o equivalent interventions, such as guided

    sel-help, exercise on prescription, and computerised

    CBT, depending on what is available locally. Patients

    entering case management can choose whether or not

    to have a combination o medication and psychological

    interventions, or medication alone.

    Patients may also be able to choose between steps,

    and choose to bypass lower level steps, i there is a

    good reason that they are inappropriate.

    However, it is important that patients decisions are

    made on the basis o good inormation. Patients who

    initiate treatment or depression should be oered

    inormation on the services currently available, as

    discussed in the section on patient assessment.

    Patients treatment preerences should be part o

    the initial assessment, and patients should also

    be encouraged to discuss their evolving treatment

    preerences with the case manager or primary care

    proessional during treatment.

    Primary Care Services

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    CHAPTER 7: ROLES FORPROFESSIONALS

    While the clinical pathways described above identiy

    proessionals to undertake specic roles, this will

    depend on local availability. No proessional should

    take on any role or which they have not received

    training or which they do not eel competent to

    undertake.

    The ollowing recommendations maybe useul:

    GPs

    Initial assessment

    Patient education

    Initial medication prescription

    Practice nurse, graduate primary care

    mental health worker

    Screening

    Patient education

    Follow up and monitoring o progress

    Guided sel-help

    Signposting

    Group psycho-education

    Assisting with computerised cognitive

    behaviour therapy

    Case management in moderate depression

    Primary care mental health

    proessionals, counsellors

    Brie CBT

    Brie counselling

    Gateway workers, practitioner with a special

    interest, mental health nurses

    Supervision or primary care proessionals

    Training or primary care proessionals in the

    recognition and management o depression

    Strengthening links between primary and

    secondary care interace

    Case management in severe depression

    Mental health specialist (psychiatrist,

    psychological therapist, mental health nurse)

    Diagnosis where dicult in primary care

    Specialist medication advice

    Specialist longer term psychological therapy

    Consultation, support and supervision or primary

    care proessionals and case manager

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    CHAPTER 8: INTERFACE ISSUES

    As well as improving primary care mental health

    services, eective management o depression in

    primary care will require improvements at the primary-

    secondary care interace. To achieve this, proessionals

    working in both primary and secondary care will need

    to work together and have agreed mechanisms or

    communication.

    Protocols between primary and specialist mental health

    services can be written which enable patients who

    have been successully treated by specialist services

    to be urther treated and/or monitored in primary care.

    An example might be a patient who makes an almostull recovery ollowing a short inpatient stay and may

    only require brie intervention or case management by

    a primary care proessional.

    The new incentives to screen patients on the diabetes

    and coronary heart disease registers means there is

    potential or increased case-nding o people with

    complex co-morbid problems at moderate severity and

    above. Dealing with these sorts o problems requires

    close working between primary care and mental

    health teams. Research examining interventions to

    improve outcomes or both diabetes and depression

    have shown mixed results, and have shown it is

    generally easier to impact on depression symptoms

    than diabetes outcomes. The same is broadly true

    or coronary heart disease - treating depression

    improves the signs and symptoms o depression in

    these patients, but there is less compelling evidence

    at present that it improves the morbidity and mortality

    associated with coronary heart disease.

    As well as eective interace between primary and

    secondary care, the employment agenda highlighted

    by Lord Layard also suggests the need or more

    eective working between health and employmentagencies, or example the services o Job Centre Plus

    and condition management programmes run by the

    Department o Work and Pensions (DWP).

    Primary Care Services

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    CHAPTER 9: CASE STUDIES

    Case study 1 - Mild depression

    Week 0 - Initial/screening appointment (GP)

    Mr Clarkson presents to the GP with a recent history

    o headaches and stiness in his joints which has

    been aecting his sleep or the past weeks. Physical

    examination does not indicate any physical cause. The

    screening questions are positive, and assessment o

    severity indicates that Mr Clarkson is suering rom mild

    depression. Treatment options in steps 1 and are

    discussed and Mr Clarkson says that he does not eel

    he needs anything specic at this time. The GP gives thepatient some materials on depression and suggests Mr

    Clarkson make another appointment in weeks time to

    review the situation.

    Week 2 - Review appointment (GP)

    Two weeks later, the assessment indicates no symptoms,

    and it is agreed that no urther action is required.

    Case study 2 - Mild depression

    Week 0 - Initial/screening appointment (GP)

    Mrs Jones is a year-old teacher who presents to

    her GP complaining o poor sleep and appetite and

    tearulness or the past our or ve weeks. A physical

    examination indicates no abnormalities. The GP asks

    the patient the two screening questions and ollowing

    a positive response asks specic questions about

    symptoms, impact and risk and completes the ICD-10.

    The patient is asked to complete the screening tool (PHQ-

    9). Both scores are indicative o mild depression and this

    is discussed with the patient. The patient agrees she

    has been eeling a little ed-up and drinking slightly more

    alcohol than normal but isnt at risk and has no previous

    history. The patient shows some interest in psychological

    therapy, and the GP gives the patient an inormation

    leafet on available therapies, and suggests the patient

    might wish to use some sel help materials in the rst

    instance. An appointment is made to see the graduateworker to discuss some guided sel-help in more detail.

    Week 2 - Guided sel-help session 1 (graduate primary

    care mental health worker)

    The graduate primary care mental health worker briefy

    discusses the nature o the patients problems and

    possible materials that may be o use. They decide on

    a depression sel-help book, and the graduate primary

    care mental health worker suggests scheduling pleasant

    activities more regularly, and shows the patient how themanual can help with this. They make an appointment

    or weeks. This inormation is ed back to the GP by

    addition in the medical records.

    Week 4 - Guided sel-help session (graduate primary

    care mental health worker)

    The patient and worker discuss the patients use o

    the manual and any diculties that have arisen. Other

    activities are also discussed. The patient continues to be

    concerned about her alcohol consumption so the worker

    gives her contact details or the local voluntary alcohol

    support service. This inormation is added to the medical

    records.

    Week 6 - Guided sel-help session (graduate primary

    care mental health worker)

    The patient and worker continue to discuss the patients

    use o the manual. The patient did contact the voluntary

    alcohol service and has signed up or a support group.

    Week 8 Monitoring session (graduate primary caremental health worker)

    The worker gets the patient to complete the PHQ-9.

    Scoring the questionnaire indicates that the patients

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    problems have remitted. The patient is happy to continue

    using the manual and attending the voluntary support

    group. The results o the assessment are ed back to the

    GP and entered onto the medical record. The patient isremoved rom the workers caseload.

    Case study 3 - Moderate to

    severe depression

    Week 0 - Initial/screening appointment (GP)

    Mr Allen attends surgery complaining o not eeling right

    since being made redundant months ago. Unable to

    establish any specic physical complaints the GP asks

    Mr Allen what he is doing with his time and discovers that

    the patient is spending most o his time in the house just

    watching TV. He has stopped going to his darts matches

    as it all seems like too much eort. Completion and

    scoring o the ICD-10 and PHQ-9 indicates a moderate

    level o depression. The patient also discloses that he

    had a similar depression when his wie let him years

    ago. He has never posed a risk to himsel or others but

    on this occasion has thought his amily would be better

    o without him. The GP probes into this urther and

    using the recommended risk questions asks i the patient

    has made any plans to act on his thoughts. Having

    established that Mr Allen has no plans to harm himsel

    because he would leave too much debt or his daughter,

    the GP discusses the treatment options with the patient.

    The GP and the patient agree to try medication. The GP

    prescribes an anti-depressant which has minimal risk in

    overdose and explains side-eects, the time required or

    medication to work and any possibility o increasing the

    dose in the uture to therapeutic levels. The GP explains

    to the patient that he will be assigned a practice nurse

    to manage his case and support and assist him over the

    next ew months, who will contact him by telephone in

    the next week to discuss the medication. The patient is

    given a patient inormation leafet on depression and an

    appointment to be seen in the clinic at the practice held

    by the local Citizens Advice Bureau regarding his debt

    problems.

    Week 1 Initial ollow up (Practice nurse)

    One week later the practice nurse contacts Mr Allen to

    discuss his medication, answer any queries he has, and to

    give support. The nurse establishes that he orgot about

    his CAB appointment and reschedules him another one

    and agrees to remind him by telephone the aternoon

    beore the appointment.

    Weeks 3, 5, 7, 9 Follow up (Practice nurse)

    The practice nurse continues to contact Mr Allen to

    discuss his medication, answer any queries he has, and to

    give support. Mr Allen did attend his appointment and is

    being supported by the CAB worker to deal with his debts.

    Week 12 Progress review session (Practice nurse)

    The PN sees Mr Allen to conduct a review o his progress

    with the PHQ-9. Scoring the questionnaire indicates that

    Mr Allen has had a partial response to the medication.

    Further discussion indicates some problems with

    loneliness Mr Allen is assisted to increase his social

    support through activity scheduling/behavioural activation

    and using local support groups. Mr Allen is happy with this

    and does not wish to change his medication at present.

    This inormation is discussed with the GP and added to

    the medical records.

    Months 2, 4, 8, 10 post acute phase (Practice Nurse)

    The PN conducts telephone ollow-up, checks progress is

    maintained and discusses medication.

    Months 6 and 12 (Practice Nurse)

    The patient is invited or an appointment with the Practice

    Nurse to review progress and the PHQ9 is completed.

    Primary Care Services

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    CHAPTER 10: AUDIT AND MONITORING

    Patients on a practice list with depression will need

    to be identiable through the clinical record keeping

    system (oten reerred to as registers). For audit

    purposes it would also be benecial to classiy the

    depression (i.e. mild, severe, atypical etc).

    It is recommended that this identication record

    should be separate rom any Severe Mental Illness

    (SMI) registers.

    It is recommended that audit involves checking the

    ollowing are being undertaken:

    Primary care has protocols in place or the

    screening o high-risk groups and that these

    protocols are adhered to

    Screening tools are used to aid diagnosis

    Standard questionnaires are used to monitor

    progress

    Patients are oered the appropriate number o

    monitoring and review appointments

    Medication is prescribed appropriately andmonitored regularly:

    Not used or mild depression

    Inormation is given to the patient

    Prescribed in accordance with NICE guidelines

    Maintenance prescribing is monitored regularly

    Appropriate psychological therapies are available

    and oered to the patient

    Patient satisaction is monitored (using a standardpatient satisaction questionnaire)

    APPENDICES

    Appendix 1: Screening or Depression in

    High Risk GroupsDuring the last month, have you oten been bothered

    by eeling down, depressed or hopeless?

    and

    During the last month, have you oten been bothered

    by having little interest or pleasure in doing things?

    I the patients response to BOTH questions is no, the

    screen is negative.

    I the patient responds yes to EITHER question, use arecommended screening tool (Appendix and ).

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    7

    Appendix 2: Assessing the severity o

    depression (ICD-10 Primary Care Version)

    KEY SYMPTOMS

    Have any o the ollowing occurred most o the time or two weeks or more:

    A. Persistent sadness or low mood.......................................

    B. Loss o interest or pleasure.......................................

    C. Fatigue or low energy.....................................

    ASSOCIATED SYMPTOMS1. Sleep disturbance.. ....................................

    Diculty alling asleep

    Early morning wakening

    . Appetite disturbance......................................

    Appetite loss

    Appetite increase

    . Poor concentration or indecisiveness.......................................

    . Agitation or slowing o movement ....................................

    . Decreased libido......................................

    . Low sel condence....................................

    7. Suicidal thoughts or acts....................................

    8. Guilt or sel-blame...................................

    I YES to any o the above, continue below

    Conclusion:

    Positive to A,B or C and:

    o the associated symptoms above = MILD- o the associated symptoms = MODERATE

    7 or more o the associated symptoms = SEVERE

    Primary Care Services

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    8

    Appendix 3: Other scales or the

    assessment o severity and outcome

    Patient Health Questionnaire (PHQ-9). Developed

    specically or primary care and used widely in the US.

    Items relate closely to the criteria or depression in the

    DSM-IV. Copyright Pzer Inc. Details are provided in

    Appendix 9 and 10. Can be downloaded ree rom:

    www.depression-primarycare.org/clinicians/toolkits/

    materials/orms/phq9/questionnaire/

    General Health Questionnaire (GHQ) (1 items). Easy

    to complete and well validated. Available in several

    languages. Available rom NFER-Nelson Publishing Co

    Ltd Tel: 08 0197).

    Hospital Anxiety and Depression Scale (HADS) (1

    items). Used requently in primary care, especially

    useul with patients who also have physical illness.

    Available rom NFER-Nelson Publishing Co Ltd Tel:

    08 0197.

    Beck Depression Inventory (BDIII) (1 items) Copyright

    belongs to the Psychological Corporation and can be

    purchased at www.pnotebook.com

    Geriatric Depression Scale (GDS) is used or screening

    with the elderly. Not subject to copyright. Can be

    downloaded rom www.miahonline.org

    Edinburgh Postnatal Depression Scale (EPDS) is

    commonly used by health visitors to screen or

    postnatal depression. Not subject to copyright and can

    be downloaded rom www.priory.com/psych.htm

    See also Cox, J. and Holden, J. (199) Perinatal

    Psychiatry: use and misuse o the Edinburgh Postnatal

    Depression Scale. London: Gaskell.

    The CORE-OM is a patient completed outcome

    measure and part o the CORE System. It is a -item

    questionnaire designed to measure clients global

    distress, including subjective well-being, commonly

    experienced problems, unctioning, and risk. Although

    protected by copyright, no charge is made or the

    CORE-OM and practitioners who are interested inusing it can photocopy materials i their content is not

    changed in any way. Further inormation on training,

    support systems and sotware are available at

    www.coreims.co.uk/index.php

    These questionnaires can be used to assess severity

    and monitor progress.

    Most scales can be completed by patients whilst in

    the waiting area. Patients who have diculty reading

    or are non-English speakers may require additionalhelp. Minimal sta input is required or the scoring o

    responses.

    Appendix 4: Asking About Risk

    Intention - thoughts

    Do things ever eel that bad that you think about

    harming or killing yoursel?

    Do you ever eel that lie is not worth living?

    Plans

    Have you made plans to end you lie?

    Do you know how you would kill yoursel?

    Actions

    Have you made any actual preparations to kill yoursel?

    Have you ever attempted suicide in the past?

    Prevention

    How likely is it that you will act on such thoughts

    and plans?

    What is stopping you killing or harming yoursel

    at the moment?

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    9

    Risk Factors or Suicide:

    Recent marital confict

    Currently untreated severe mental illness

    Alcohol abuse

    Previous suicide attempts

    It is also important to ask about risk to others,

    especially where patients are not known to the primary

    care practice. An example question might be Have you

    ever been in trouble with the police?

    Categorising risk

    Appendix 5: Asking About Alcohol

    Problems the CAGE Questionnaire

    Have you ever elt you ought to Cut down

    on your drinking?

    Have peopleAnnoyed you by criticising your drinking?

    Have you ever elt bad or Guilty about your drinking?

    Have you ever had a drink rst thing in the morning

    to steady your nerves or get rid o a hangover (Eye-

    opener)?

    Two or more Yes responses yield a positive screen

    test or alcohol.

    Risk Description Action

    Low risk No current

    thoughts, or

    inrequent

    thoughts

    Continue ollow-up

    visits and monitor.

    Normalise thoughts

    and dierentiate

    between thoughts

    and actions.

    Intermediate

    risk

    Frequent

    currentthoughts but no

    plans or intent

    Assess risk careully

    at each visit. Liasewith specialist

    mental health

    service. Ensure

    patient knows how

    to access services.

    High risk Current

    thoughts with

    plans and

    preparations

    Reer to specialist

    mental health

    service and engage

    in collaborative

    approach to

    treatment and

    monitoring.

    Primary Care Services

    or Depression

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    0

    Appendix 6: AUDIT Questionnaire: Screen

    For Alcohol Misuse27

    Please circle the answer that is correct or you

    1. How oten do you have a drink containing alcohol?

    Never

    Monthly or less

    times a month

    times a week

    or more times a week

    . How many standard drinks containing alcohol do

    you have on a typical day when drinking?

    1 or

    or

    or

    7 to 9

    10 or more

    . How oten do you have six or more drinkson one occasion?

    Never

    Less than monthly

    Monthly

    Weekly

    Daily or almost daily

    . During the past year, how oten have you ound

    that you were not able to stop drinking once you

    had started?

    Never

    Less than monthly

    Monthly

    Weekly

    Daily or almost daily

    . During the past year, how oten have you ailed to

    do what was normally expected o you because

    o drinking? Never

    Less than monthly

    Monthly

    Weekly

    Daily or almost daily

    . During the past year, how oten have you needed

    a drink in the morning to get yoursel going ater a

    heavy drinking session?

    Never

    Less than monthly

    Monthly

    Weekly

    Daily or almost daily

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    1

    7. During the past year, how oten have you had a

    eeling o guilt or remorse ater drinking?

    Never

    Less than monthly

    Monthly

    Weekly

    Daily or almost daily

    8. During the past year, have you been unable

    to remember what happened the night beore

    because you had been drinking?

    Never

    Less than monthly

    Monthly

    Weekly

    Daily or almost daily

    9. Have you or someone else been injured as a

    result o your drinking?

    No

    Yes, but not in the past year

    Yes, during the past year

    10.Has a relative or riend, doctor or other health

    worker been concerned about your drinking or

    suggested you cut down?

    No

    Yes, but not in the past year

    Yes, during the past year

    Scoring the audit

    Scores or each question range rom 0 to , with the

    rst response or each question (e.g. never) scoring 0,

    the second (e.g. less than monthly) scoring 1, the third

    (e.g. monthly) scoring , the ourth (e.g. weekly) scoring

    , and the last response (e.g. daily or almost daily)

    scoring . For questions 9 and 10, which only have

    three responses, the scoring is 0, and .

    A score o 8 or more is associated with harmul or

    hazardous drinking. A score o 1 or more in women,

    and 1 or more in men, is likely to indicate

    alcohol dependence.

    Primary Care Services

    or Depression

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    APPENDIX 7: RELEVANT PATIENTINFORMATION RESOURCES

    Many GPs have the variety o leafets available at

    www.patient.co.ukon their computers or printing or

    individual patient use.

    Below are some o the other web-sites and

    organisations rom where patient inormation leafets

    can be accessed or purchased.

    MIND produces a variety o leafets, some o which are

    available in languages other than English. They can be

    printed by individuals or ordered on-line or a cost to

    organisations www.mind.org.uk

    The Royal College o Psychiatrists produce leafets on

    depression, anti-depressants and psychotherapy in a

    variety o languages which can be printed rom

    www.rcpsych.ac.uk

    The British Association o Behavioural and Cognitive

    Psychotherapies (BABCP) have leafets on depression,

    sel-help which are printable or available to order at a

    cost www.babcp.com

    Depression Alliance have a number o on-line patient

    inormation leafets on depression and available

    treatments www.depressionalliance.org/

    The Mental Health Foundation have leafets available to

    order at cost and can be printed rom the web-site by

    individual patients www.mentalhealth.org.uk

    The Department o Health has produced a ree leafet

    with inormation on dierent psychological therapies

    www.doh.gov.ukand search or talking therapies.

    APPENDIX 8: TREATMENTS AT STEP 2

    Guided sel-help

    Sel-help involves providing patients with both

    inormation about a condition and skills and techniques

    to overcome symptoms and assist with problems. These

    skills and techniques are oten based on cognitive-

    behaviour therapy (CBT). Guided sel-help is appropriate

    or mild depression.

    There is some evidence rom the UK that pure sel-

    help through written materials improves outcomes or

    patients in primary care,1,8 and that guided sel-help

    can be conducted by non-mental health specialists suchas practice nurses.9,0

    A comprehensive sel-help booklet or depression can

    be ordered rom the Oxord Cognitive Therapy Centre at

    www.octc.co.uk/html/sel-help.html

    Overcoming Depression is written by Chris Williams,

    and two o the chapters on Problem Solving and Being

    Assertive are available ree o charge at

    www.calipso.co.uk

    Newcastle, North Tyneside and Northumberland MentalHealth Trust sel-help booklets are available ree to

    download at www.nnt.nhs.uk/mh/

    Computerised CBT

    Computerised packages may be designed to unction

    with very little guidance, although monitoring o outcome

    is still recommended. There is evidence rom the UK that

    computerised CBT (with brie guidance) is clinically and

    cost-eective in primary care.1

    The National Institute o Clinical Excellence has reviewed

    the evidence or computerised packages and provided

    guidance. www.nice.org.uk/page.aspx?o=ta097

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    Reerral acilitation (signposting)

    Reerral acilitation involves assessing a patient and

    helping them nd appropriate local or national voluntary

    organisations. On occasion, statutory organisations

    may be suggested or new support groups established.

    Reerral acilitation is based on the availability o local

    groups, up to date inormation on their scope, and

    agreement rom these groups concerning reerral. It is

    recommended that a proessional such as a graduate

    worker visits groups in order to gather inormation on a

    pro-orma concerning each group, which allows easy

    and rapid sharing o inormation about

    available resources.

    Reerral acilitation is appropriate or mental health

    problems o mild to moderate severity, and may be

    relevant or patients with depressive symptoms who

    are acing particular psychosocial diculties or which

    there are relevant groups available.

    There is one study in the UK that suggests that reerral

    acilitation improves patient outcome.17 There is one

    ongoing UK trial that is examining the eects o reerral

    acilitation specically by graduate primary care mental

    health workers.

    Group psycho-education

    Group psycho-education or depression is group

    treatment which involves providing inormation about

    depression, issues that aect mood, how to identiy

    and change thoughts, activities and interactions that

    aect mood, relaxation training, and goal planning.

    Groups o -10 people are ormed on a locality basis

    and each group meets or 8, hour sessions.

    Because o the educational nature o the intervention,

    it can be used in a variety o settings, including

    those outside health such as adult education. The

    intervention can be used in a preventive capacity (i.e.in patients at risk o developing depression) or with

    patients with specic depressive problems.

    Group psychoeducation is appropriate or mild

    depression. There is evidence rom UK primary care

    that group psychoeducation is eective.18

    Exercise on Prescription

    Exercise on Prescription (EoP) can be used as a non-

    drug treatment in the treatment o depression and aims

    to help people increase their physical activity.

    Being physically active can assist in the recovery

    o depression and can also prevent against re-

    occurrence. However, seven in ten adults are not

    active enough to get the health benets. The EoP

    Government schemes aim to tackle health inequalities

    by improving access to sport and exercise.

    Many o the schemes already in operation have

    established links with local leisure centres and patients

    can access the equipment and receive regular advice

    and monitoring rom qualied registered tness

    proessionals. National standards or EoP have

    been published by the Department o Health which

    encourage the development o new and eective high

    quality projects nationwide.

    There is some evidence that exercise is eective in

    improving depression. Guidance is available at

    www.dh.gov.uk/PolicyAndGuidance/HealthAndSocialCareTopics/HealthyLiving/s/en

    Primary Care Services

    or Depression

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    APPENDIX 9: WEBSITES WITHINFORMATION ON THECOLLABORATIVE CARE AND CASE

    MANAGEMENT APPROACH

    Helping the Chronically Ill through Quality Improvement

    and Research (a national program o the Robert Wood

    Johnson Foundation)

    www.improvingchroniccare.org

    The MacArthur Initiative on Depression in Primary Care

    www.depression-primarycare.org

    The Health Disparities Collaborative

    www.healthdisparities.net

    APPENDIX 10: PHQ-9MONITORING TOOL(COPYRIGHT PFIzER)

    The Patient Health Questionnaire (PHQ-9) is a brie

    9-item patient sel-report questionnaire specically

    developed or use in primary care and used extensively

    in the United States. The PHQ-9 has acceptable

    reliability, validity, sensitivity and specicity as an

    assessment tool or the diagnosis o depression in

    primary care. The questionnaire can also be used to

    monitor progress with possible scores ranging rom

    0 to 7 with higher scores indicative o

    increasing severity.

    www.depression-primarycare.org

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    1. Over the last 2 weeks, how oten have you been bothered by any o the ollowing problems?

    Read each item careully, and circle your response.

    a. Little interest or pleasure in doing things

    Not at all Several days More than hal the days Nearly every day

    b. Feeling down, depressed, or hopeless

    Not at all Several days More than hal the days Nearly every day

    c. Trouble alling asleep, staying asleep, or sleeping too much

    Not at all Several days More than hal the days Nearly every day

    d. Feeling tired or having little energyNot at all Several days More than hal the days Nearly every day

    e. Poor appetite or overeating

    Not at all Several days More than hal the days Nearly every day

    . Feeling bad about yoursel, eeling that you are a ailure, or eeling that you have

    let yoursel or your amily down

    Not at all Several days More than hal the days Nearly every day

    g. Trouble concentrating on things such as reading the newspaper or watching television

    Not at all Several days More than hal the days Nearly every day

    h. Moving or speaking so slowly that other people could have noticed.

    Or being so fdgety or restless that you have been moving around a lot more than usual

    Not at all Several days More than hal the days Nearly every day

    i. Thinking that you would be better o dead or that you want to hurt yoursel in some way

    Not at all Several days More than hal the days Nearly every day

    2. I you checked o any problem on this questionnaire so ar, how difcult have these problems made

    it or you to do your work, take care o things at home, or get along with other people?

    Not Dicult at All Somewhat Dicult Very Dicult Extremely Dicult

    Scoring the PHQ-9 when used to measure severity involves counting one point or each o the 9 items in

    question 1 ticked several days, two points or each ticked hal the days and three points or those ticked

    nearly every day. Sum the total or a severity score.

    Patient Name Date

    Primary Care Services

    or Depression

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    APPENDIX 11: RECOMMENDED

    CATEGORIES FOR RESPONSE AND

    MONITORING WITH THE PHQ-9

    Defnition o improvement

    Improved A reduction o or more points

    on the baseline score

    Not improved Drop o 1 point or no change or

    increase

    Defnition o remission

    A PHQ-9 score o less than is the eventual goal o

    acute phase treatment. When this goal is achieved,

    patients enter the continuation phase o treatment.

    Changes o treatments within steps and stepping up

    are considered or patients who do not meet this goal.

    SCORE SEVERITY CLINICAL PATHWAY

    0 Severe depression Step or

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    7

    REFERENCES

    1 LAYARD R. The case or psychological treatment

    centres. BMJ 00;:100-10.

    HARKNESS E, BOWER P, GASK L, SIBBALD B.

    Improving primary care mental health: survey

    evaluation o an innovative workorce

    development in England. Primary Care Mental

    Health 2006;(in press).

    USTUN T, AYUSO-MATEOS J, CHATTERJI

    S, MATHERS C, MURRAY C. Global burden

    o depressive disorders in the year 000. Br J

    Psychiatry 2004; 18:8-9.

    GOLDBERG D, HUXLEY P. Common MentalDisorders: A biosocial model. London:

    Routledge, 199.

    KATON W, VON KORFF M, LIN E, ET AL.

    Population-based care o depression: eective

    disease management strategies to decrease

    prevalence. Gen Hosp Psychiatry 1997;19:BMJ

    00;:100-10.

    FREELING P, KENDRICK T. INTRODUCTION.

    IN: T KENDRICK, A TYLEE, P FREELING, EDS.

    The Prevention o Mental Illness in Primary Care.

    Cambridge: Cambridge University Press,

    1997;1-18.

    7 PAYKEL E, PRIEST R. Recognition and

    management o depression in general practice:

    consensus statement.

    BMJ 1992;0:1198-10.

    8 THOMPSON C, KINMONTH A, STEVENS L, ET al.

    Eects o a clinical practice guideline and practice-

    based education on detection and outcome o

    depression in primary care: Hampshire Depression

    Project randomised controlled trial.

    Lancet 2000;:18-191.

    9 KATON W, VON KORFF M, LIN E, SIMON G.

    Rethinking practitioner roles in chronic illness: the

    specialist, primary care physician and the practice

    nurse. Gen Hosp Psychiatry 2001;:18-1.

    10 GILBODY S, WHITTY P, GRIMSHAW J, THOMAS R.

    Educational and organisational interventions

    to improve the management o depression

    in primary care: a systematic review.JAMA

    2003;89:1-11.

    11 GASK L. Role o specialists in common chronic

    diseases. BMJ 2005;0:1-.

    1 DEPARTMENT OF HEALTH. Treatment Choice

    in Psychological Therapies and Counselling:Evidence based clinical practice guideline.

    London. Department o Health, 2001.

    1 PRIEST R, VIZE C, ROBERTS A, ROBERTS M,

    TYLEE A. Lay peoples attitudes to treatment

    o depression: results o opinion poll or Deeat

    Depression Campaign just beore its launch. BMJ

    1996;1:88-89.

    1 ANDERSON L, LEWIS G, ARAYA R, ET AL. Sel-

    help books or depression: how can practitioners

    and patients make the right choice? BritishJournal o General Practice 2005;:87-9.

    1 LOVELL K, RICHARDS D. Multiple Access Points

    and Levels o Entry (MAPLE): Ensuring Choice,

    Accessibility and Equity or CBT Services.

    Behaviour Cognitive Psychotherapy

    2000;8:79-91.

    1 PROUDFOOT J, RYDEN C, EVERITT B, ET AL.

    Clinical ecacy o computerised cognitive-

    behavioural therapy or anxiety and depression in

    primary care: randomised controlled trial.

    British Journal o Psychiatry 2004;18:-.

    Primary Care Services

    or Depression

  • 7/29/2019 Managementul Depresiei in Medicina Primara

    38/46

    8

    17 GRANT C, GOODENOUGH T, HARVEY I, HINE C.

    A randomised controlled trial and economic

    evaluation o a reerrals acilitator between

    primary care and the voluntary sector. BMJ2000;0:19-.

    18 DOWRICK C, DUNN G, AYUSO-MATEOS J-L, ET AL.

    Problem solving treatment and group

    psychoeducation or depression: multicentre

    randomised controlled trial. BMJ 2000;321:1-6.

    19 SCOGIN F, HANSON A, WELSH D.

    Sel-administered treatment in stepped-care

    models o depression treatment.Journal o

    Clinical Psychology 2003;9:1-9.

    0 SOBELL M, SOBELL L. Stepped care as a

    heuristic approach to the treatment o alcohol

    problems.Journal o Consultant Clinical

    Psychology 2000;8:7-79.

    1 DAVISON G. Stepped care: doing more with

    less?Journal o Consultant Clinical Psychology

    2000;8:80-8.

    ANDREWS G. Should depression be managed as

    a chronic disease? BMJ 2001;:19-1.

    KENDRICK T. Depression management clinics ingeneral practice? BMJ 2000;0:7-8.

    VON KORFF M, GOLDBERG D. Improving

    outcomes in depression. BMJ 2001;:98-99.

    KATON W, VON KORFF M, LIN E, ET AL.

    The Pathways study: a randomized trial o

    collaborative care in patients with diabetes and

    depression.Archives o General Psychiatry

    2004;1:10-109.

    VIEWEG W, JULIUS D, FERNANDEZ A, ET AL.

    Treatment o depression in patients in coronary

    heart disease.American Journal o the Medical

    Sciences 2006;119:7-7.

    7 SAUNDER J, AASLAND O, BABOR T.

    Development o the alcohol use disorders

    identication test (AUDIT): WHO collaborative

    project on early detection o persons withharmul alcohol consumption II.Addiction

    1993;88:791-80.

    8 BOWER P, RICHARDS D, LOVELL K. The clinical

    and cost-eectiveness o sel-help treatments or

    anxiety and depressive disorders in primary care:

    a systematic review. British Journal o General

    Practice 2001;1:88-8.

    9 RICHARDS D, RICHARDS A, BARKHAM M,

    CAHILL J, WILLIAMS C. PHASE: a health

    technology approach to psychological treatmentin primary mental health care. Primary Health Care

    Research and Development 00;:19-18.

    0 RICHARDS A, BARKHAM M, CAHILL J,

    RICHARDS D, WILLIAMS C, HEYWOOD P.

    PHASE: a randomised, controlled trial o

    supervised sel-help cognitive behavioural

    therapy in primary care. British Journal o General

    Practice 2003;:7-770.

    1 PROUDFOOT J, GOLDBERG D, MANN A,

    EVERITT B, MARKS I, GRAY J. Computerized,

    interactive, multimedia cognitive-behavioural

    program or anxiety and depression in general

    practice. Psychol Med 2003;:17-7.

    COOPER H, LESTER H, FREEMANTLE N,

    WILSON S. A cluster randomised controlled trial

    o the eect o primary care mental health workers

    on satisaction, mental health symptoms and

    use o services: background and methodology.

    Primary Care Psychiatry 2003;9:1-7.

    LAWLOR D, HOPKER S. The eectiveness o

    exercise as an intervention in the management

    o depression: systematic review and meta-

    regression analysis o randomised controlled

    trials. BMJ 2001;:7

  • 7/29/2019 Managementul Depresiei in Medicina Primara

    39/46

    9

    USEFUL RESOURCES

    Books & Reports

    Department o Health (1999) National service

    ramework or Mental Health: Modern Standards and

    service models. London, Department o Health.

    Department o Health (1999). Saving Lives: Our

    Healthier Nation. London, HMSO.

    www.dh.gov.uk/assetRoot/0/0/9/9/0099pd

    National service ramework or mental health: modern

    standards and service models.

    www.dh.gov.uk/assetRoot/0/07/7/09/007709.pd

    Executive Summary: Saving lives: Our Healthier Nation

    is an action plan to tackle poor health.

    Department o Health (000) The NHS Plan ~ A plan

    or investment, A plan or reorm. London, Department

    o Health.

    www.dh.gov.uk/assetRoot/0/0/7/8/0078.pd

    Department o Health (001). The Mental Health Policy

    Implementation Guide. London, Department o Health.

    www.dh.gov.uk/assetRoot/0/0/89/0/00890.pd.

    This policy guidance supports the delivery o adult

    mental health policy locally.Department