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J U L Y 2 0 1 5 E d i t i o n 7
University Hospitals Case Medical Center delivers
stroke clot-buster better than national average in new
benchmark report Ohio Department of Health Coverdell Stroke Program presents
data on UH performance
CLEVELAND -- A new benchmark report from the Ohio
Department of Health Coverdell Stroke Program shows that
University Hospitals Case Medical Center is 12.4 percent better
than the national average in administering the clot-busting drug t-
PA within 60 minutes or less of the patient’s arrival at the
emergency department (“door-to-needle time”) and 15.5 percent
ahead of Ohio hospitals participating in the report.
The clot-buster t-PA is intravenous tissue-type plasminogen
activator, which is the only FDA approved drug for dissolving the
blockage at the root of ischemic strokes. The benefits of t-PA in
acute ischemic stroke are time dependent, and guidelines call for it
to be administered within 60 minutes of a patient arriving at the
emergency department.
Other highlights of the report include that the medical center is 16.5
percent ahead of the Ohio average in scheduling primary care
provider follow-up appointments and nearly 35 percent ahead of the
Ohio average in scheduling follow-up appointments with
neurologists – both prior to being discharged home. According to
the report, follow-up care with a primary care provider can facilitate
recovery from stroke.
(Continued on page 2)
Terry Adelman, Volunteer Co-chair Claire Morgan, Volunteer Co-chair
Helen Braun Anthony J. Caruso, PhD Diane Collier David E Cook David & Karen Crane Jeffrey Cristal Michael Cristal Anthony Furlan, MD Kimberly Ganley Judy Goodman Sally Gries Cynthia Halle Jennie Hwang, PhD Robert Jackson, Esq. Wendy Adelman Kampinski Ruth H. Kanner Cynthia Lammert Russ & Connie Lincoln Richard & Marilyn Miller Katherine O'Neill Lee Powar Howard Rabb Stanley & Sue Rubin Gordon & Evelyn Safran Thomas Scherr Gail Schlang Mark & Christina Schumann Warren Selman, MD Margaret Singerman Virginia Spitz Rick Stege, Esq. Lester Stoller Robert & Shelly Wallens Steven & Joni Wasserman Stephen & Penni Weinberg Sheila Wyse Daniel & Ellen Zelman Mary Jo Zingale
Warren Selman, MD Department Chairman, Neurological Surgery UHCMC Neurosurgeon-in-Chief, UH Neurosurgery Director,
Neurological Institute, UHCMC
Anthony Furlan, MD Department Chairman, Neurology UHCMC Co-Director,
Neurological Institute, UHCMC
Rebecca Kahl, MBA Interim Director of Operations
Tracy Gruschow
Interim NI Practice Manager
MESSAGE FROM THE DIRECTORS
Neurological Institute Leadership
Council Members
Neurological Institute Leadership
JUNE, 2015 2
STAFF CHANGES AND
SPECIAL ANNOUNCEMENTS
WELCOME Fernandez Baca Vaca, MD will join the
Department of Neurology Epilepsy Center
in July, 2015.
Yin Hu, MD will join the Department of
Neurological Surgery in July, 2015.
Stacy Loejos, RN, will join the
Department of Neurological Surgery as
RN to Dr. Jonathan Miller.
FAREWELL Doris Evans, Academic Education
Coordinator is retiring effective July 17,
2015. You are invited to a reception in
honor of Doris on July 17th in the 5th Floor
Bolwell Conference Rooms 5198/5199
beginning at 2 pm – 5 pm. Kindly RSVP
by July 15th to
[email protected] or call
(216) 983-5741.
Kim Pierce, Secretary, resigned and
transitioned to UH Pain Management on
June 26, 2015.
John Turnbull, Neurological Image &
System Engineer, resigned and
transitioned to CWRU on May 25, 2015.
ROBERT DAROFF, MD
INTERVIEWED BY AAN Dr. Robert Daroff gave an oral history
interview with Dr. Douglas Lanska, a
former UH Neurology resident on behalf
of The American Academy of Neurology.
The entire interview consisting of 5
Appendices are available for access
through the link listed below. Oral
History Interview Transcripts:
www.AAN.com/membership/history
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
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(Continued from page 1)
In addition UH Case Medical Center exceeded the national
average in eight of ten quality measures. “One American dies
from stroke every four minutes and it is a leading cause of
serious long-term disability,” said Dr. Sila. “We continually
strive to make improvements in our rapid response to strokes
at UH Case Medical Center and through our regional stroke
network at our community hospitals.”
“The Coverdell program is a data-driven quality
improvement program demonstrating that we are delivering
the right care at the right time for our patients and it gives us
a roadmap for future developments,” said Dr. Sila. “Research
shows that getting treated at a primary stroke center staffed
by medical experts using the latest technologies gives a
patient the best chance for a favorable outcome and fuller
recovery,” she said.
Warren Selman, MD Anthony Furlan, MD Chairman, Neurological Surgery Chairman, Department of Neurology
Director, Neurological Institute Co-Director, Neurological Institute
DR. MAUREEN MCENERY ELECTED
FACULTY COUNCIL CHAIR Case Western Reserve University’s School of Medicine
recently held Faculty Council Elections and our own, Dr.
Maureen W. McEnery, Associate Professor in the
Department of Neurology with a secondary appointment in
the Department of Neuroscience was elected as the next
Faculty Council chair-elect. The Steering Committee for the
2015-2016 academic year is: Bill Schilling (Chair), Mark
Aulisio (past-Chair), Maureen McEnery (Chair-elect), Mark
Aeder, Devra Becker, Colleen Croniger, William Merrick,
and Nicole Ward. Dr. Jo Ann Wise will serve on the
Nominating Committee. Please congratulate Dr. McEnery in
accepting this role of service.
NEW PROGRAMS AND SERVICES UH Systems Stroke Program Initiative focuses on admitting
low-risk ICH patients to UH Ahuja, based on data collected
at UHCMC and presented at the American Stroke
Association International Stroke Conference in February by
Dr. Oladi Bentho, UH Department of Neurology and Dr. Wei
Xiong, UH Department of Neurology.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 3
PROFESSIONAL PRESENTATIONS
AND CONFERENCES
Brian S. Appleby, MD, UH Department of Neurology Psychiatry, was an invited presenter at the CJD Support Group Network Annual Meeting, Melbourne, Australia, October 19, 2014. Topic: "Why do prion diseases look so different?"
PUBLICATIONS Brei TJ, Woodrome SE, Fastenau PS, Buran CF, Sawin KJ. Depressive Symptoms in Parents of Adolescents with Myelomeningocele: The Association of Clinical, Adolescent Neuropsychological Functioning, and Family Protective Factors. Journal of Pediatric Rehabilitation Medicine. In press, 2014.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
CENTERS OF EXCELLENCE
University Hospitals Offers Leading
Neurological Expertise
Across 15 Centers of Excellence
At University Hospitals Neurological Institute, a
team of nationally recognized experts deliver
comprehensive, coordinated care for disorders of
the brain and nervous system.
Recognized by U.S. News and World Report as
one of the finest neurology and neurosurgery
programs in the country, UH Neurological
Institute delivers innovative, integrated and
individualized care to patients with diseases
affecting the nervous system at convenient
locations throughout northern Ohio.
With 15 centers of excellence, UH Neurological
Institute delivers individualized treatment,
innovative techniques and access to some of the
most innovative research designed to advance
the science of neurological medicine.
For example, we are the only U.S. hospital
offering multiple hippocampus transections as a
surgical solution to eliminate seizures and
effectively cure epilepsy. Also, we were the first
in the world to test diaphragm pacing
stimulation.
This technique can slow the rate of breathing
failure in patients with amyotrophic lateral
sclerosis (ALS) or Lou Gehrig's disease.
Innovative, Integrated and
Individualized Care for Patients
with Neurological Disorders
University Hospitals Neurological Institute
in Cleveland – the leading institute in
Northeast Ohio – offers the full range of
neurological and neurosurgical services at
our primary location, UH Case Medical
Center.
In addition, patients can be seen close to
home at one of our many community
medical and health centers.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
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INAUGURAL ROBERT J. MACIUNAS
LECTURE The Inaugural Robert J. Maciunas Lecture was held on
Wednesday, May 13th to honor the life and career of Dr.
Maciunas who was the Director of the Gamma Knife Center, the
Center for Image-Guided Neurosurgery and served as Vice
Chairman of the Department of Neurological Surgery at
University Hospitals Case Medical Center.
He was well known for his many advances in the field of
stereotactic and functional neurosurgery, pioneering several
techniques for brain surgery, particularly for helping patients
with Tourette syndrome.
Douglas Kondziolka, M.D., MSc, Professor and Director of the
Center for Advanced Radiosurgery at NYU Langone Medical
Center and Vice Chair of Clinical Research at New York
University School of Medicine, was the invited speaker and
gave a presentation entitled, “If not us, then who.” Dr.
Maciunas’ wife, Ann Failinger, and his two sons Joseph and
Nicholas were in attendance.
(L to R) Dr. Warren Selman, Nicholas Maciunas, Dr. Ann
Failinger, Joseph Maciunas, and Dr. Douglas Kondziolka
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 4
DEGREES AND PROFESSIONAL
CERTIFICATIONS EARNED Cathy Sila, MD, UH Department of Neurology received
an Advancing Manager Certificate, from the
Weatherhead School of Management
Cathy Sila, MD, UH Department of Neurology, -
Vascular Neurology Board Recertification
RESEARCH TRIALS AND STUDIES Protocol Synopsis DAWN™ Trial - DWI or CTP Assessment
with Clinical Mismatch in the Triage of Wake Up and Late
Presenting Strokes Undergoing Neurointervention
Primary Objective: To evaluate the hypothesis that Trevo
thrombectomy plus medical management leads to superior
clinical outcomes at 90 days as compared to medical
management alone in appropriately selected subjects
experiencing an acute ischemic stroke when treatment is
initiated within 6-24 hours after last seen well.
Study Design: Prospective, randomized, multi-center, Phase
II/III (feasibility/pivotal), adaptive, population enrichment,
blinded endpoint, controlled trial. Subjects will be randomized
1:1 to Trevo thrombectomy plus medical management or
medical management alone. Stratification will occur by:
Clinical Imaging Mismatch (CIM) subgroup (see Imaging
Inclusion Criteria), Time Last Seen Well (TLSW) ≥ 6 to < 12
hours vs. >12 to ≤ 24 hours, and Baseline Occlusion Location
(ICA vs. M1).
Planned Number of Subjects: A maximum of 500 subjects is
planned to be enrolled; 250 in the Treatment arm and 250 in the
Control arm. The minimum sample size is 150 subjects. We
expect to enroll 10 patients at UHCMC
Primary Endpoint: Difference between the average weighted
modified Rankin Scale score at 90 days between the active and
control groups.
Study Duration: Enrollment: approximately 36 months;
Subject participation: 90 days (± 14)
For General inclusion criteria information, please contact
the Coordinator Val Cwiklinski RN (pager 35588) or the
Principal Investigator Dr. Cathy Sila for more information.
Or go to ClinicalTrials.gov and search Trevo and Medical
Management.
RESEARCH TRIALS AND STUDIES
contd. Study of Deferoxamine Mesylate in Intracerebral
Hemorrhage (iDEF). This is a prospective, multi-
center, double-blind, randomized, placebo-
controlled, phase-II clinical trial. Subjects will be
randomized to either deferoxamine mesylate (DFO)
at 32 mg/kg/day (up to a maximum daily dose of
6000 mg/day), or saline placebo, given by IV
infusion for 3 consecutive days. Treatment will be
initiated within 24 hours after ICH symptom onset.
Randomization will control baseline imbalances
associated with baseline ICH score, ICH onset-to-
treatment time (OTT), ICH volume, baseline
NIHSS score, and warfarin use. All subjects will be
followed for 6 months and will receive standard of
care therapy while participating in the study.
Throughout the study, we will continue to assess the
safety of DFO. At the conclusion of the study, the
proportion of DFO-treated subjects with a good
clinical outcome at 3 months (defined as modified
Rankin Scale (mRS) score of 0-2) will be compared
to the placebo proportion in a futility analysis to
determine if it is futile to move DFO forward to
Phase III efficacy evaluation.
Michael DeGeorgia is the PI of the
study. Research nurses are Dave Korosec, RN, (cell
phone 440-477-4971) and Valerie Cwiklinski, RN,
(cell phone 440-220-0168 or pager #35588).
CLINICAL TRIALS
NRG BN002: Phase I Study of Ipilimumab,
Nivolumab, and the Combination in Patients with
Newly Diagnosed Glioblastoma, an NCI-funded
multicenter trial co-Chaired by Dr. Andrew Sloan,
was approved by CTEP, the FDA and the NIH
Central IRB and will open at 10 sites in July-
August, 2015.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 5
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UH GEAUGA MEDICAL CENTER
RECOGNIZED AS ONE OF THE 2015
AMERICA’S BEST STROKE CENTERS UH Geauga Medical Center earned the Women’s
Choice Award for American’s Best Stroke Centers.
This distinction is the first of its kind in the nation and
is awarded to hospitals that carry the certification of
an Advanced Primary Stroke Center or Advanced
Comprehensive Stroke Center by the Joint
Commission combined with achieving above average
patient recommendation scores.
PROFESSIONAL PRESENTATIONS Shivam Om Mittal, MD participated in presenting
two poster presentations at the 19th Movement
Disorder Society International Congress on June
17th-June 18th.
Shivam Om Mittal, Duarte G Machado.
Wide spectrum of clinical presentation of
ataxia with occulomotor apraxia type II.
Shivam Om Mittal, Ashish Ranpura, Arash
Salarhdini, Bahman Jabbari. Hand
stereotypies in Wilson's disease
Jun Park, MD, Asim Shahid, MD, UH Department
of Pediatric Epilepsy, Jonathan Miller, MD, UH
Department of Neurosurgery and Han Lüders, MD,
UH Department of Neurology presented at the 8th
International Epilepsy Colloquium in Grenoble,
France on June 17, 2015. Topic: "Infant with TSC 1
Mutation and focal status epileptics treated with
Leukotomy at 3 months of age."
.
Andrew Sloan, MD, UH Department of
Neurological Surgery, lectured on "Cancer Related
Cord Compression” to UHMG and Seidman
Cancer Center Clinicians on May 13, 2015.
Andrew Sloan, MD, UH Department of
Neurological Surgery, was the invited Oral
Platform presenter on Brain Tumors: What the
Neurosurgeon Wants at the International Society
for MRI in Medicine, in Toronto, CA, May 31,
2015.
Andrew Sloan, MD, UH Department of
Neurological Surgery was the invited Oral
Platform presenter on Laser Interstitial
Thermotherapy (LITT) vs. Stereotactic
Radiosurgery (SRS). Complementary rather than
Competing Technologies at the International
Gamma Knife Meeting.
Andrew Sloan, MD, UH Department of
Neurological Surgery presented on Laser
Interstitial Thermotherapy for the treatment of
newly diagnosed GBM at the AANS Tumor
Satellite Symposium, in Washington, DC, May
2015.
Andrew Sloan, MD, presented on MRI
Fingerprinting for Diagnosis of Malignant Glioma
and Assessment of Treatment Response at the
AANS Tumor Satellite Symposium, in
Washington, DC, May 2015.
Andrew Sloan, MD, D. Bondy, P. Harris and A.
Kerstetter-Fogle presented on The Role of the
Robo-Slit family of Genes in GBM Invasion at the
AANS Annual Meeting, in Washington, DC, May
2015 (Oral)
Andrew Sloan, MD, UH Department of
Neurological Surgery presented on The Role of the
Neurosurgeon in Brain Tumor Clinical Trials at the
AANS Annual Meeting, in Washington, DC, May
2015.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 6
SAVE THE DATE - Mark your calendars!
2015 CLEVELAND HYDROCEPHALUS ASSOCIATION WALK The UH Neurological Institute and Rainbow Babies and Children’s Hospital are proud to be a Gold sponsor
of the 2015 Cleveland Hydrocephalus Association WALK on Sunday, August 30. We will be creating a
team for the walk and would be thrilled if you could join us to show support for our patients with
hydrocephalus. If you are interested in walking with us, please e-mail Bri Martinez at
[email protected] to let her know of your interest and for details on registering for the
walk. We will be ordering team t-shirts, price TBD, so please also include your t-shirt size in the email.
7th ANNUAL PARKINSON DISEASE BOOT CAMP Saturday, September 19, 2015
John S. Knight Center
77 East Mill Street, Akron, OH
For more information contact Barbara Bryson at [email protected]
WALK TO END ALZHEIMER'S CLEVELAND AREA CHAPTER September 13, 2015 at the Lake Farm Park, Kirtland, OH http://act.alz.org/site/TR/Walk2015/OH-
ClevelandArea?fr_id=7708&pg=entry
September 19, 2015 at the All Pro Freight Stadium, Avon, OH http://act.alz.org/site/TR/Walk2015/OH-
ClevelandArea?fr_id=7706&pg=entry
September 27, 2015 at the Cleveland Metroparks Zoo, Cleveland,
OH http://act.alz.org/site/TR/Walk2015/OH-ClevelandArea?fr_id=7707&pg=entry
For more information contact Katie Mang at [email protected].
2015 CLEVELAND HEART AND STROKE WALK Saturday, September 26, 2015 – The NI is looking for someone to volunteer to serve as the team captain to
organize a NI group to participate in this year’s walk. If you are interested, please contact Julie Fussner or
Barbara Bryson as soon as possible. [email protected] or [email protected]
4TH ANNUAL DAN AND LINDA ROCKER SILVERBERG HEAL THE HEALER
SYMPOSIUM Friday, October 16, 2015 7:30 am – 4:30 pm
700 Beta Banquet & Conference Center
700 Beta Drive, Mayfield Village, OH 44143
To register for the symposium, call 216 983-1239 – More information to come!
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 7
EDUCATION OPPORTUNITIES GRAND ROUNDS SCHEDULE
Epilepsy Grand Rounds – Frohring Auditorium – CANCELLED FOR THE SUMMER
Neurology Grand Rounds Kulas Auditorium 8 am – CANCELLED FOR THE SUMMER
Neuromuscular Grand Rounds – Lerner Tower 2nd Fl., Room 2060 9:30 am - CANCELLED FOR
THE SUMMER
Pediatric Epilepsy Grand Rounds – RBC 8th Floor Conference Room 11:00 am
Every 4th Monday of the month
Topic: Case Management
Neurosurgical Clinical Conference – Hanna House 5th Floor, Room 537 7:15 am
TBA
If you have any questions regarding department Grand Rounds schedule, please contact:
Lois Hengenius, Neurosurgery Clinical Conference, 216 844-3472
Angela Javorsky, Epilepsy Grand Rounds, 216 844-1764
Roberta Phelps, Neuromuscular Grand Rounds, 216 844-4854
Kim Puskus, Neurology Grand Rounds, 844-3194
Angel Warner, Pediatric Epilepsy Course 216-286-6562
Carlee Seelbach, Connor Integrative Medicine Network 216-593-5533
DAISY AWARD – JOE FAULKNER, RN, NSU
Joe Faulkner RN, NSU received the Daisy Award. DAISY is an acronym for Diseases Attacking the Immune
System. In 1999 the Foundation was formed by the family of J. Patrick Barnes, who at age 33 died of complications
of Idiopathic Thrombocytopenic Purpura (ITP). In Patrick's memory his family started The DAISY Program to
recognize the skillful and amazingly compassionate care he received from his nurses. Congratulations Joe!
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 8
PUBLICATIONS Awan M, Liu S, Sahgal A, Das S, Chao ST, Chang EL, Knisely JP, Redmond K, Sohn JW, Machtay M, Sloan
AE, Mansur DB, Rogers LR, Lo SS. Extra-CNS metastasis from glioblastoma: a rare clinical entity. Expert
Rev Anticancer Ther. 2015 May;15(5):545-52. doi: 10.1586/14737140.2015.1028374. PubMed PMID:
25907706.
Blixen C, Perzynski A, Cage J, Smyth K, Moore S, Sila C, Pundik S, Sajatovic M. Using focus groups to
inform the development of stroke recovery and prevention programs for younger African-American
men. Topics in Stroke Rehabilitation 2015.
Blixen C, Perzynski A, Cage J, Smyth K, Moore S, Sila C, Pundik S, Sajatovic M. Stroke recovery and
prevention barriers among young african-american men: potential avenues to reduce health disparities. Topics
in Stroke Rehabilitation 21(5):432-42, 2014.
Brandt WD, Schreck KC, Bar EE, Taylor I, Marchionni L, Raabe E, Eberhart CG, Rodriguez FJ. Notch
signaling activation in pediatric low-grade astrocytoma. JNeuropathol Exp Neurol. 2015 Feb;74(2):121-31. doi:
10.1097/NEN.0000000000000155. PubMed PMID: 25575134; PubMed Central PMCID: PMC4357229.
Brat DJ et al …Sloan,AE, Barnholtz-Sloan J, Cohen ML, Ostrom Q and others. Cancer Genome Atlas
Research Network, Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N
Engl J Med. 2015 Jun 25;372(26):2481-98. doi: 10.1056/NEJMoa1402121. Epub 2015 Jun 10. PubMed PMID:
26061751.
Brett-Morris A, Wright BM, Seo Y, Pasupuleti V, Zhang J, Lu J, Spina R, Bar EE, Gujrati M, Schur R, Lu
ZR, Welford SM. The polyamine catabolic enzyme SAT1modulates tumorigenesis and radiation response in
GBM. Cancer Res. 2014 Dec1;74(23):6925-34. doi: 10.1158/0008-5472.CAN-14-1249. Epub 2014 Oct 2.
PubMed PMID: 25277523; PubMed Central PMCID: PMC4423404.
Chien LN, Ostrom QT, Gittleman H, Lin JW, Sloan AE, Barnett GH, Elder JB, McPherson C, Warnick R,
Chiang YH, Lin CM, Rogers LR, Chiou HY, Barnholtz-Sloan JS. International Differences in Treatment and
Clinical Outcomes for High Grade Glioma. PLoS One. 2015 Jun 10;10(6):e0129602. doi:
0.1371/journal.pone.0129602. eCollection 2015. PubMed PMID: 26061037; PubMed Central PMCID:
PMC4465035.
Kahlert UD, Suwala AK, Raabe EH, Siebzehnrubl FA, Suarez MJ, Orr BA, Bar EE, Maciaczyk J, Eberhart
CG. ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres. Brain
Pathol. 2014 Dec 17. doi: 10.1111/bpa.12240. [Epub ahead of print] PubMed PMID: 25521330; PubMed
Central PMCID: PMC4470885.
Kim B, Sila C. Seizures in Cerebrovascular Disorders, in MZ Koubeissi, A Alshekhle and P Mehndiratta (ed):
Seizures, 2015.
Kshettry VR, Hsieh JK, Ostrom QT, Kruchko C, Benzel EC, Barnholtz-Sloan JS. Descriptive Epidemiology
of Spinal Meningiomas in the United States. Spine (Phila Pa 1976). 2015 May 20. [Epub ahead of print]
PubMed PMID: 25996535.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 9
PUBLICATIONS (continued from page 8)
Kshettry VR, Hsieh JK, Ostrom QT, Kruchko C, Barnholtz-Sloan JS. Incidence of vestibular schwannomas
in the United States. J Neurooncol. 2015 May 30. [Epub ahead of print] PubMed PMID: 26024654.
Kulhari A, Kalra N, Sila C. Noncompaction Cardiomyopathy and Stroke: Case Report and Literature
Review. J Stroke Cerebrovasc Dis 2015.
Lim KJ, Brandt WD, Heth JA, Muraszko KM, Fan X, Bar EE, Eberhart CG. Lateral inhibition of Notch
signaling in neoplastic cells. Oncotarget. 2015 Jan30;6(3):1666-77. PubMed PMID: 25557173; PubMed
Central PMCID: PMC4359323.
Lym RL, Ostrom QT, Kruchko C, Couce M, Brat DJ, Louis DN, Barnholtz-Sloan JS. Completeness and
concordancy of WHO grade assignment for brain and central nervous system tumors in the United States,
2004-2011. J Neurooncol. 2015 May;123(1):43-51. doi: 10.1007/s11060-015-1775-4. Epub 2015 Apr 12.
PubMed PMID: 25864099; PubMed Central PMCID: PMC4441798.
Nakibuuka J, Sajatovic M, Nankabirwa J, Furlan AJ, Kayima J, Ddumba E, Katabira E, Byakika-Tusiime J.
Stroke risk factors differ between rural and urban communities: population survey in central
Uganda. Neuroepidemiology 44(3):156-165, 2015.
Ostrom QT, Bauchet L, Davis FG, Deltour I, Fisher JL, Langer CE, Pekmezci M, Schwartzbaum JA, Turner
MC, Walsh KM, Wrensch MR, Barnholtz-Sloan JS. Response to "the epidemiology of glioma in adults: a
'state of the science' review". Neuro Oncol. 2015 Apr;17(4):624-6. doi: 10.1093/neuonc/nov022. PubMed
PMID: 25762697.
Rabin M, Om Mittal S, Jabbari B. Tremor and Klinefelter’s syndrome. Tremor Other Hyperkinet Mov 2015;
5. doi: 10.7916/D84M93KR.
Ridgel A, Walter BL, Tatsuoka C, Walter E, Colón-Zimmermann K, Welter E, Sajatovic M. Enhanced
Exercise Therapy in Parkinson's disease: A comparative effectiveness trial. Journal of Science and Medicine
in Sport, 2015 [Epub ahead of print].
Shams T, Grossman J, Sila C. Neurologic Complications of Infectious Endocarditis, in K Roos (ed):
Neurobiology of Disease Second Edition, 2015.
Shan L, Diaz O, Zhang Y, Ladenheim B, Cadet J, Chiang Y, Olson L, Hoffer BJ, Bäckman C. L-Dopa
induced dyskinesias in Parkinsonian mice: Disease severity or L-Dopa history. Brain Research 1618:261–
269, 2015.
Virk SM, Gibson RM, Quinones-Mateu ME, Barnholtz-Sloan JS. Identification of variants in primary and
recurrent glioblastoma using a cancer-specific gene panel and whole exome sequencing. PLoS One. 2015
May 7;10(5):e0124178. doi: 10.1371/journal.pone.0124178. eCollection 2015. PubMed PMID: 25950952;
PubMed Central PMCID: PMC4423782.
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 10
NEUROLOGY & NEUROSURGERY RESIDENT & FELLOWS GRADUATIONS
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 11
NEUROLOGY & NEUROSURGERY RESIDENT & FELLOWS GRADUATIONS
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 12
NEUROLOGY & NEUROSURGERY RESIDENT & FELLOWS GRADUATIONS
Neurology PGY3 Residents presented The Dennis M. Landis
Teaching Excellence Award to Dr. Alan Lerner
Neurology PGY4 Residents presented The
Robert B. Daroff Teaching Excellence
Award to Dr. Cathy Sila
2015 Department of Neurology Residents Graduation
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 13
NEUROLOGY & NEUROSURGERY RESIDENT & FELLOWS GRADUATIONS
Saba Saeed, MD;
Guadalupe Fernandez‐ Baca Vaca, MD and
Kunal Kumar, MD Kunal Kumar, MD; Barbara Shapiro, MD and
Oladi Bentho, MD
Oladi Bentho, MD; Guadalupe Fernandez-Baca Vaca, MD;
Manaf Zawahreh, MD and
Sikawat Thanaviratananich, MD
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 14
May is stroke awareness month. This issue is so important especially when you
consider it is the third leading cause of death in the United States. Members of
the Neurological Institute administered 325 screenings at CMC and 715
throughout the whole system.
STROKE AWARENESS SCREENINGS
U H h o s p i t a l s . o r g / n e u r o 2 1 6 - 8 4 4 - 2 7 2 4
JUNE 2015 15
NI NEWSLETTER SUBMISSION INFORMATION
Next Print Date: August 4, 2015; Submission deadline: July 24th
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In an effort to keep the newsletter 10 pages or less, we are requesting that you only submit four of
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DR. EDWARD WESTBROOK’S RETIREMENT CELEBRATION – JUNE 22, 2015
Edward Westbrook, MD and Nancy
Tinsley
Edward Westbrook, MD; Anthony
Furlan, MD; Lisa Rogers, MD and
Patrick Sweeney, MD, CCF
Edward Westbrook, MD and
Michael Devereaux, MD
Michael DeGeorgia, MD; Richard Lederman, MD, CCF; Nancy
Bass, MD; Edward Westbrook, MD, Anthony Furlan, MD and
Patrick Sweeney, MD, CCF
Edward Westbrook, MD; Anita Cooper (Dr.
Westbrook’s secretary) and Lisa Rogers, MD