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DAFTAR ISI
Sampul Luar ............................................................................................................... i
Sampul Dalam ............................................................................................................. ii
Prasyarat Gelar ............................................................................................................ iii
Lembar Persetujuan .................................................................................................... iv
Surat Pernyataan Orisinalitas ...................................................................................... v
Ucapan Terima Kasih ................................................................................................. vi
Ringkasan .................................................................................................................... viii
Abstrak ........................................................................................................................ x
Abstract ....................................................................................................................... xi
Daftar Isi ..................................................................................................................... xii
Daftar Tabel ................................................................................................................ xv
Daftar Gambar ............................................................................................................ xvi
Daftar Lampiran .......................................................................................................... xvii
Daftar Singkatan ......................................................................................................... xviii
BAB I PENDAHULUAN ........................................................................................... 1
1.1 Latar Belakang ....................................................................................... 1
1.2 Rumusan Masalah .................................................................................. 4
1.3 Tujuan Penelitian ................................................................................... 4
1.3.1 Tujuan Umum .............................................................................. 4
1.3.2 Tujuan Khusus ............................................................................. 4
1.4 Manfaat Penelitian .................................................................................. 4
BAB II TINJAUAN PUSTAKA ................................................................................ 6
2.1 Definisi Cedera Otak .............................................................................. 6
2.2 Klasifikasi Cedera Otak .......................................................................... 8
2.3 Mekanisme Patofisiologis Cedera Otak secara Umum .......................... 10
IR-PERPUSTAKAAN UNIVERSITAS AIRLANGGA
SKRIPSI PROFIL PaCO2, PaO2... HUTAURUK, MARIA MARIND D
xiii
2.4 Mekanisme Patofisiologis Cedera Otak secara Khusus ......................... 11
2.4.1 Autoregulasi Pembuluh Darah Otak dan Reaktivitas CO2 ........... 11
2.4.2 Perubahan PaO2 pada Cedera Otak ............................................. 14
BAB III KERANGKA KONSEPTUAL ..................................................................... 17
3.1 Kerangka Konseptual ............................................................................. 17
3.2 Penjelasan Kerangka Konseptual ........................................................... 18
BAB IV MATERI DAN METODE PENELITIAN ................................................... 19
4.1 Rancangan Penelitian ............................................................................. 19
4.2 Populasi dan Sampel .............................................................................. 19
4.2.1 Populasi ....................................................................................... 19
4.2.2 Kriteria Inklusi Sampel ................................................................ 19
4.2.3 Sampel .......................................................................................... 20
4.3 Variabel Penelitian ................................................................................. 20
4.4 Bahan Penelitian ..................................................................................... 20
4.5 Instrumen Penelitian .............................................................................. 20
4.6 Lokasi dan Waktu Penelitian ................................................................. 20
4.7 Prosedur Penelitian ................................................................................. 21
BAB V HASIL PENELITIAN ................................................................................... 26
5.1 Gambaran Umum Hasil Penelitian ........................................................ 26
5.2 Deskripsi Data Penelitian ....................................................................... 26
5.2.1 Distribusi Pasien Cedera Otak Berat Berdasarkan
GCS (Glasgow Coma Scale) ........................................................ 27
5.2.2 Distribusi Pasien Cedera Otak Berat Berdasarkan
MAP (Mean Arterial Pressure) ................................................... 28
5.2.3 Distribusi Pasien Cedera Otak Berat Berdasarkan PaCO2 ........... 29
5.2.3.1 Keseluruhan ..................................................................... 29
5.2.3.2 Distribusi Pasien Cedera Otak Berat Berdasarkan
IR-PERPUSTAKAAN UNIVERSITAS AIRLANGGA
SKRIPSI PROFIL PaCO2, PaO2... HUTAURUK, MARIA MARIND D
xiv
PaCO2 dan GCS .............................................................. 29
5.2.4 Distribusi Pasien Cedera Otak Berat Berdasarkan PaO2 .............. 30
5.2.5 Distribusi Pasien Cedera Otak Berat Berdasarkan
Frekuensi Nafas ............................................................................ 31
5.2.7 Distribusi Pasien Cedera Otak Berat Berdasarkan
Patensi Jalan Nafas ....................................................................... 32
BAB VI PEMBAHASAN ........................................................................................... 33
6.1 Sampel Penelitian ................................................................................... 33
6.2 Pasien Cedera Otak Berat Berdasarkan MAP
(Mean Arterial Pressure) ....................................................................... 33
6.3 Pasien Cedera Otak Berat Berdasarkan PaCO2 ...................................... 34
6.4 Pasien Cedera Otak Berat Berdasarkan PaO2 ......................................... 36
6.5 Pasien Cedera Otak Berat Berdasarkan Frekuensi Nafas ....................... 37
6.6 Pasien Cedera Otak Berat Berdasarkan Patensi Jalan ............................ 38
BAB VII KESIMPULAN DAN SARAN ................................................................... 39
7.1 Kesimpulan ............................................................................................. 39
7.2 Saran ....................................................................................................... 39
DAFTAR PUSTAKA ................................................................................................. 40
LAMPIRAN ................................................................................................................ 44
IR-PERPUSTAKAAN UNIVERSITAS AIRLANGGA
SKRIPSI PROFIL PaCO2, PaO2... HUTAURUK, MARIA MARIND D
