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Investing in MENTAL HEALTH

Investing in MENTAL HEALTH - who.int · Investing in mental health today can generate enormous returns in terms of reducing disability and preventing prema-ture death. The priorities

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Page 1: Investing in MENTAL HEALTH - who.int · Investing in mental health today can generate enormous returns in terms of reducing disability and preventing prema-ture death. The priorities

Investing in

MENTAL HEALTH

Page 2: Investing in MENTAL HEALTH - who.int · Investing in mental health today can generate enormous returns in terms of reducing disability and preventing prema-ture death. The priorities

This publication was produced by the Department of Mental Health and Substance Dependence,

Noncommunicable Diseases and Mental Health, World Health Organization, Geneva.

For further information and feedback, please contact:

Department of Mental Health and Substance Dependence, Avenue Appia 20, 1211 Geneva 27, Switzerland

Tel: +41 22 791 21 11, fax: +41 22 791 41 60, e-mail: [email protected], website: www.who.int/mental_health

WHO Library Cataloguing-in-Publication Data

World Health Organization.

Investing in mental health.

1.Mental disorders - economics 2.Mental disorders - therapy 3.Mental health services - economics

4.Mental health services - economics 5.Cost of illness 6.Investments I.Title.

ISBN 92 4 156257 9 (NLM classification: WM 30)

© World Health Organization 2003

All rights reserved. Publications of the World Health Organization can be obtained from Marketing and Dissemination, World Health

Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel: +41 22 791 2476; fax: +41 22 791 4857; email:

[email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial

distribution – should be addressed to Publications, at the above address (fax: +41 22 791 4806; email: [email protected]).

The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatso-

ever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities,

or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there

may not yet be full agreement.

The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by

the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the

names of proprietary products are distinguished by initial capital letters.

The World Health Organization does not warrant that the information contained in this publication is complete and correct and shall

not be liable for any damages incurred as a result of its use.

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Page 3: Investing in MENTAL HEALTH - who.int · Investing in mental health today can generate enormous returns in terms of reducing disability and preventing prema-ture death. The priorities

Introduction 3

Executive Summary 4

What is mental health? 7

The magnitude and burdens of mental disorders 8

The economic burden of mental disorders 14

Promoting mental health; preventing and managing mental ill health 26

The gap between the burden of mental disorders and resources 36

WHO Global Action Programme (mhGAP) 40

Much can be done; everyone can contribute to better mental health 43

References 46

For more information 48

Content

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Mental health has been hidden behind a curtain of stigma and discrimination for too long. It is time to bring it out into

the open. The magnitude, suffering and burden in terms of disability and costs for individuals, families and societies

are staggering. In the last few years, the world has become more aware of this enormous burden and the potential

for mental health gains. We can make a difference using existing knowledge ready to be applied.

We need to enhance our investment in mental health substantially and we need to do it now.

What kinds of investment?

Investment of financial and human resources. A higher proportion of national budgets should be allocated to develop-

ing adequate infrastructure and services for mental health. At the same time, more human resources are needed to

provide care for those with mental disorders and to protect and promote mental health. Countries, especially those

with limited resources, need to establish specifically targeted policies, plans and initiatives to promote and support

mental health.

Who needs to invest? All of us with interest in the health and development of people and communities. This includes

international organizations, development aid agencies, trusts/foundations, businesses and governments.

What can we expect from such investment?

It should be able to provide the much-needed services, treatment and support to a larger proportion of the nearly

450 million people suffering from mental disorders than they receive at present: services that are more effective and

more humane; treatments that help them avoid chronic disability and premature death; and support that gives them

a life that is healthier and richer – a life lived with dignity. We can also expect greater financial returns from increased

productivity and lower net costs of illness and care, apart from savings in other sector outlays.

Overall, this investment will result in individuals and communities who are better able to avoid or cope with the stress-

es and conflicts that are part of everyday life, and who will therefore enjoy a better quality of life and better health.

Lee Jong-wook

Introductionby the Director-General

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For all individuals, mental, physicaland social health are vital and inter-woven strands of life. As our under-standing of this relationship grows, it becomes ever more apparent thatmental health is crucial to the overallwell-being of individuals, societies andcountries. Indeed, mental health canbe defined as a state of well-beingenabling individuals to realize their

abilities, cope with the normal stressesof life, work productively and fruitful-ly, and make a contribution to theircommunities. Unfortunately, in mostparts of the world, mental health andmental disorders are not accordedanywhere near the same degree ofimportance as physical health. Rather,they have been largely ignored orneglected.

This publication aims to guide you inthe discovery of mental health, in themagnitude and burdens of mental dis-orders, and in understanding what canbe done to promote mental health inthe world and to alleviate the burdensand avoid deaths due to mental disor-ders. Effective treatments and inter-ventions that are also cost-effectiveare now readily available. It is there-fore time to overcome barriers andwork together in a joint effort to nar-row the gap between what needs tobe done and what is actually beingdone, between the burden of mentaldisorders and the resources being usedto address this problem. Closing thegap is a clear obligation not only forthe World Health Organization, butalso for governments, aid and devel-opment agencies, foundations,research institutions and the businesscommunity.

Executive Summary

The magnitude and burdens of the problem

• As many as 450 million people suffer from a mental or behavioural disorder.

• Nearly 1 million people commit suicide every year.

• Four of the six leading causes of years lived with disability are due to

neuropsychiatric disorders (depression, alcohol-use disorders, schizophrenia

and bipolar disorder).

• One in four families has at least one member with a mental disorder.

Family members are often the primary caregivers of people with mental

disorders. The extent of the burden of mental disorders on family members

is difficult to assess and quantify, and is consequently often ignored.

However, it does have a significant impact on the family’s quality of life.

• In addition to the health and social costs, those suffering from mental

illnesses are also victims of human rights violations, stigma and discrimi-

nation, both inside and outside psychiatric institutions.

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The economic burden of mental disorders

Given the prevalence of mental health and substance-dependence problems in adults and children, it is not surprising

that there is an enormous emotional as well as financial burden on individuals, their families and society as a whole.

The economic impacts of mental illness affect personal income, the ability of ill persons – and often their caregivers –

to work, productivity in the workplace and contributions to the national economy, as well as the utilization of treatment

and support services. The cost of mental health problems in developed countries is estimated to be between 3% and

4% of GNP. However, mental disorders cost national economies several billion dollars, both in terms of expenditures

incurred and loss of productivity. The average annual costs, including medical, pharmaceutical and disability costs, for

employees with depression may be 4.2 times higher than those incurred by a typical beneficiary. However, the cost of

treatment is often completely offset by a reduction in the number of days of absenteeism and productivity lost while

at work.

Alleviating the problem: prevention, promotion and management programmes

A combination of well-targeted treatment and prevention programmes in the field of mental health, within overall pub-

lic strategies, could avoid years lived with disability and deaths, reduce the stigma attached to mental disorders, increase

considerably the social capital, help reduce poverty and promote a country’s development.

Studies provide examples of effective programmes targeted at different age groups – from prenatal and early infancy

programmes, through adolescence to old age – and different situations, such as post-traumatic stress following acci-

dents, marital stress, work-related stress, and depression or anxiety due to job loss, widowhood or adjustment to retire-

ment. Many more studies need to be conducted in this area, particularly in low- and middle-income countries. There is

strong evidence to show that successful interventions for schizophrenia, depression and other mental disorders are not

only available, but are also affordable and cost-effective.

Yet there is an enormous gap between the need for treatment of mental disorders and the resources available. In devel-

oped countries with well organized health care systems, between 44% and 70% of patients with mental disorders do

not receive treatment. In developing countries the figures are even more startling, with the treatment gap being close

to 90%.

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Investing in mental health today can generate enormous returns in terms of reducing disability and preventing prema-ture death. The priorities are well known and the projects and activities needed are clear and possible. It is our respon-sibility to turn the possibilities to reality.

6

WHO’s Mental Health Global Action Programme (mhGAP)

To overcome barriers to closing the gap between resources and the need for treatment of mental disorders, and to

reduce the number of years lived with disability and deaths associated with such disorders, the World Health Organiza-

tion has created the Mental Health Global Action Programme (mhGAP) as part of a major effort to implement the rec-

ommendations of the World Health Report 2001 on mental health. The programme is based on strategies aimed at

improving the mental health of populations. To implement those strategies, WHO is undertaking different projects and

activities, such as the Global Campaign against Epilepsy, the Global Campaign for Suicide Prevention, building national

capacity to create a policy on alcohol use, and assisting countries in developing alcohol-related services. WHO is also

developing guidelines for mental health interventions in emergencies, and for the management of depression,

schizophrenia, alcohol-related disorders, drug use, epilepsy and other neurological disorders. These projects are designed

within a framework of activities which includes support to countries in monitoring their mental health systems, formulat-

ing policies, improving legislation and reorganizing their services. These efforts are largely focused on low- and middle-

income countries, where the service gaps are the largest.

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Mental health is more than the mere lack

of mental disorders. The positive dimen-

sion of mental health is stressed in WHO’s

definition of health as contained in its con-

stitution: “Health is a state of complete

physical, mental and social well-being and

not merely the absence of disease or infir-

mity.” Concepts of mental health include

subjective well-being, perceived self-effica-

cy, autonomy, competence, intergenera-

tional dependence and recognition of the

ability to realize one’s intellectual and emo-

tional potential. It has also been defined as

a state of well-being whereby individuals

recognize their abilities, are able to cope

with the normal stresses of life, work pro-

ductively and fruitfully, and make a contri-

bution to their communities. Mental health

is about enhancing competencies of indi-

viduals and communities and enabling

them to achieve their self-determined

goals. Mental health should be a concern

for all of us, rather than only for those

who suffer from a mental disorder.

Mental health problems affect society

as a whole, and not just a small, isolated

segment. They are therefore a major

challenge to global development. No

group is immune to mental disorders,

but the risk is higher among the poor,

homeless, the unemployed, persons with

low education, victims of violence,

migrants and refugees, indigenous popu-

lations, children and adolescents, abused

women and the neglected elderly.

For all individuals, mental, physical and

social health are closely interwoven, vital

strands of life. As our understanding of

this interdependent relationship grows, it

becomes ever more apparent that mental

health is crucial to the overall well-being

of individuals, societies and countries.

Unfortunately, in most parts of the world,

mental health and mental disorders are

not accorded anywhere the same impor-

tance as physical health. Rather, they

have been largely ignored or neglected.

The burden of mental disorders is expected to rise significantly over the next 20 years:

Are we doing enough to address the growingmental health challenges?

What is mental health?

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The magnitude and burdens of mental disorders

Today, about 450 million people suffer from a mental or behaviouraldisorder. According to WHO’s GlobalBurden of Disease 2001, 33% of theyears lived with disability (YLD) aredue to neuropsychiatric disorders, afurther 2.1% to intentional injuries(Figure 1). Unipolar depressive disor-ders alone lead to 12.15% of yearslived with disability, and rank as thethird leading contributor to the globalburden of diseases. Four of the sixleading causes of years lived with disability are due to neuropsychiatricdisorders (depression, alcohol-use disorders, schizophrenia and bipolardisorder).

Neuropsychiatric conditions accountfor 13% of disability adjusted lifeyears (DALYs), intentional injuries for3.3% and HIV/AIDS for another 6%(Figure 2). These latter two have abehavioural component linked tomental health. Moreover, behindthese oft-repeated figures lies enor-mous human suffering.

• More than 150 million persons suf-fer from depression at any point intime;

• Nearly 1 million commit suicideevery year;

• About 25 million suffer fromschizophrenia;

• 38 million suffer from epilepsy; and

• More than 90 million suffer from analcohol- or drug-use disorder.

The number of individuals with disor-ders is likely to increase further in viewof the ageing of the population, wors-ening social problems and civil unrest.

This growing burden amounts to ahuge cost in terms of human misery,disability and economic loss.

A huge toll2

Malignant neoplasms 5%

Diabetes 1%

Other NCDs 1%

Malaria 3%Childhood diseases 3%

Other CD causes 6%

Injuries 12%

Congenital abnormalities 2%

Neuropsychiatric disorders 13%

HIV/AIDS 6%Tuberculosis 2%

Diarrhoeal diseases 4%

Sense organ disorders 3%

Cardiovascular diseases 10%

Diseases of the genitourinary system 1%

Respiratory diseases 4%

Digestive diseases 3%Musculoskeletal diseases 2%

Respiratory infections 6%Maternal conditions 2%

Perinatal conditions 7%Nutritional deficiencies 2%

Burden of diseases worldwide: Disability adjusted life years (DALYs), 2001

Source: WHR, 2002

1

Neuropsychiatric disorders

Others

Source: WHR, 2002

33%

67%

Years lived with disability (YLD): World

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Mental and behavioural problems as risk factors for morbidity and mortality

It is becoming increasingly clear thatmental functioning is fundamentallyinterconnected with physical andsocial functioning and health out-comes. For example, depression is arisk factor for cancer and heart dis-eases. And mental disorders such asdepression, anxiety and substance-use disorders in patients who also suffer from physical disorders mayresult in poor compliance and failureto adhere to their treatment sched-ules. Furthermore, a number ofbehaviours such as smoking and sex-ual activities have been linked to thedevelopment of physical disorderssuch as carcinoma and HIV/AIDS.

Among the 10 leading risk factors forthe global burden of disease measuredin DALYs, as identified in the WorldHealth Report 2002, three were men-tal/behavioural (unsafe sex, tobaccouse, alcohol use) and three otherswere significantly affected by men-tal/behavioural factors (overweight,blood pressure and cholesterol).

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Comorbidity, which signifies the simul-taneous occurrence in a person of twoor more disorders, is a topic of consid-erable and growing interest in thecontext of health care. Research sup-ports the view that a number of men-tal disorders (e.g. depression, anxiety,substance abuse) occur in people suf-fering from both non-communicableand communicable diseases moreoften than would be expected bychance. And people suffering fromchronic physical conditions have agreater probability of developingmental disorders such as depression.Rates of suicide are higher amongpeople with physical disorders thanamong other people.

Comorbidity results in lower adher-ence to medical treatment, an increasein disability and mortality, and higherhealth costs. However, comorbid men-tal disorders are often underrecog-nized and not always effectivelytreated. Increased awareness andunderstanding, as well as comprehen-sive integrated management may alle-viate the burden caused by comorbidmental disorders on the individual,society and the health services.

Mental disorders and medical illness are interrelated

Treating comorbid depression could increase adherence

to interventions for chronic medical illness

Comorbid depression is the existence of a depressive disorder (i.e. major

depression, dysthymia or adjustment disorder) along with a physical disease

(infectious, cardiovascular diseases, neurological disorders, diabetes mellitus

or cancer). It is neither a chance phenomenon nor a mere feeling of demoral-

ization or sadness brought on by the hardships of a chronic illness. While the

prevalence of major depression in the general population can go from an

average 3% up to 10%, it is consistently higher in people affected by chronic

disease (Figure 3).

Patients with comorbid depression are less likely to adhere to medical treat-

ment or recommendations, and are at increased risk of disability and mortality.

For example, it has been shown that depressed patients are three times more

likely not to comply with medical regimens than non-depressed patients;

there is also evidence that depression predicts the incidence of heart disease.

In the case of infectious diseases, non-adherence can lead to drug resistance,

and this has profound public health implications concerning resistant infec-

tious agents.

Illness-associated depression impairs quality of life and several aspects of the

functioning of patients with chronic diseases; moreover, it results in higher

health care utilization and costs.

Clinical trials have consistently demonstrated the efficacy of antidepressant

treatment in patients with comorbid depression and chronic medical illness.

Such treatment improves their overall medical outcomes.

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0 10 20 30 40 50

3

Hypertension

Myocardial infarction

Epilepsy

Stroke

Diabetes

Cancer

HIV/AIDS

Tuberculosis

General population

Prevalence of major depression in patients with physical illnesses

up to 29%

up to 22%

up to 30%

up to 31%

up to 27%

up to 33%

up to 44%

up to 46%

up to 10%

Source: WHO, 2003, unpublished document

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Family members are often the primarycaregivers of people with mental dis-orders. They provide emotional andphysical support, and often have tobear the financial expenses associatedwith mental health treatment andcare. It is estimated that one in fourfamilies has at least one member cur-rently suffering from a mental orbehavioural disorder. In addition tothe obvious distress of seeing a loved-one disabled by the consequences of a mental disorder, family members arealso exposed to the stigma and dis-crimination associated with mental illhealth. Rejection by friends, relatives,neighbours and the community as a

whole can increase the family’s senseof isolation, resulting in restrictedsocial activities, and the denial ofequal participation in normal socialnetworks.

Informal caregivers need more sup-port. The failure of society toacknowledge the burden of mentaldisorders on affected families meansthat very little support is available tothem. Expenses for the treatment ofmental illness are often borne by thefamily because they are generally notcovered by the State or by insurance.Family members may need to setaside a significant amount of their

time to care for a person with a men-tal disorder. Unfortunately, the lack ofunderstanding on the part of mostemployers, and the lack of specialemployment schemes to address thisissue, sometimes render it difficult forfamily members to gain employmentor to hold on to an existing job, orthey may suffer a loss of earnings dueto days taken off from work. Thiscompounds the financial costs associ-ated with treating and caring forsomeone with a mental disorder.

Family burden cannot be ignored

Mental disorders: a significant burden on the family.

The burden of mental disorders goes beyond that which has been definedby Disability Adjusted Life Years.

The extent of the burden of mental disorders on family members is difficultto assess and quantify, and is consequently often ignored. However, it doeshave a significant impact on the family’s quality of life.

Talking about mental disorders means talking about stigma and human rights

ing conditions. For example, therehave been documented cases of peo-ple being tied to logs far away fromtheir communities for extensive peri-ods of time and with inadequate food,shelter or clothing. Furthermore, oftenpeople are admitted to and treated inmental health facilities against theirwill. Issues concerning consent foradmission and treatment are oftenignored, and independent assessmentsof capacity are not undertaken. This

Persons with mental disorders oftensuffer a wide range of human rightsviolations and social stigma.

In many countries, people with mentaldisorders have limited access to themental health treatment and care theyrequire, due to the lack of mentalhealth services in the area in whichthey live or in the country as a whole.For example, the WHO Atlas Surveyshowed that 65% of psychiatric bedsare in mental hospitals, where condi-

tions are extremely unsatisfactory.Inpatient places should be movedfrom mental hospitals to general hospitals and community rehabilita-tion services.

Violations in psychiatricinstitutions are rife

Many psychiatric institutions haveinadequate, degrading and evenharmful care and treatment practices,as well as unhygienic and inhuman liv-

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In addition to the social and economic toll,those suffering from mental illnesses are alsovictims of human rights violations, stigmaand discrimination.

Human rights violations of people with mental disorders: the voice of sufferers

Caged beds

Many psychiatric institutions, general hospitals and social care homes in countries continue to use caged beds routinely

to restrain patients with mental disorders and mental retardation. Caged beds are beds with netting or, in some cases,

metal bars, which serve to physically restrain the patients. Patients are often kept in caged beds for extended periods,

sometimes even years. This type of restraint is often used when staff levels or training are inadequate, and sometimes

as a form of punishment or threat of punishment. The use of restraints such as caged beds restricts the mobility of

patients, which can result in a number of physical hazards such as pressure sores, not to mention the harmful psycho-

logical effects. People have described the experience as being emotionally devastating, frightening, humiliating, degrad-

ing and disempowering. (Caged Beds – Inhuman and Degrading Treatment in Four EU Accession Countries, Mental

Disability Advocacy Center, 2003)

Chained and burned due to accidental fire

August 2001: Twenty-five people were charred to death in Erwadi, India. A devastating fire broke out at 5 a.m. in the

asylum. Of the 46 with mental disorders, 40 had been chained to their beds. Erwadi had long been considered a holy

place, famous for its dargah. During the course of the “treatment”, the persons with mental disorders were frequently

caned, whipped and beaten up in the name of “driving away the evil”. During the day, they were tied to trees with

thick ropes. At night, they were tied to their beds with iron chains. (www.indiatogether.org)

means that people can be lockedaway for extensive periods of time,sometimes even for life, despite hav-ing the capacity to decide their futureand lead a life within their community.

Violations also occur outsideinstitutions: the stigma of mentalillness

In both low- and high-income coun-tries, there is a long history of peoplewith mental disorders being stigma-

tized along with their families. This ismanifested by stereotyping, fear,embarrassment, anger, and rejectionor avoidance. The myths and miscon-ceptions associated with mental disor-ders negatively affect the day-to-daylives of sufferers, leading to discrimi-nation and the denial of even themost basic human rights. All over theworld, people with mental disordersface unfair denial of employment andeducational opportunities, and dis-crimination in health insurance and

housing policies. In certain countries,mental disorders can be grounds fordenying people the right to vote andto membership of professional associ-ations. In others, a marriage can beannulled if the woman has sufferedfrom a mental disorder. Such stigmaand discrimination can, in turn, affecta person’s ability to gain access toappropriate care, recover from his orher illness and integrate into society.

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Given the prevalence of mental healthand substance-dependence problemsin adults and children, the emotional,but also financial, burden on individu-als, their families and society as a

whole is enormous, as noted earlier.The economic impacts of mental ill-ness include its effects on personalincome, the ability of the persons withmental disorders or their caregivers to

To gauge the measurable economicburden of mental illness, in table 2 thediverse economic impacts have beentransformed into a single cost-basedmeasure, and organized by types of

The economic burden of mental disorders

costs based on expenditures made orresources lost.

An important characteristic of mentaldisorders is that mortality is relativelylow, onset often occurs at a young age,

and the indirect costs derived from lostor reduced productivity in the work-place are high.

work and make productive contribu-tions to the national economy, as wellas the utilization of treatment andsupport services (Table 1).

Table 1. The overall economic burden of mental disorders

Table 2. Types of measurable costs

Care costs Productivity costs Other costs

Sufferers Treatment and service Work disability; Anguish/suffering;fees/payments lost earnings treatment side-effects; suicide

Family and friends Informal care-giving Time off work Anguish; isolation; stigma

Employers Contributions to treatment and care Reduced productivity –

Society Provision of mental health care Reduced productivity Loss of lives;and general medical care untreated illnesses(taxation/insurance) (unmet needs); social exclusion

Core costs Other non-health costs

Direct costs • Treatment and service fees/payments • Social welfare administration(payments made) • Public and private criminal justice system

• Transportation

Indirect costs • Morbidity costs (in terms of value of lost productivity) • Value of family caregivers’ time(resources lost) • Mortality costs

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Estimates of costs are not available forall the various disorders, and certainlynot for all the countries in the world.Most methodologically sound studieshave been conducted in the UnitedStates and the United Kingdom. At1990 prices, mental health problemsaccounted for about 2.5% of GNP inthe United States (Rice et al., 1990).In the Member States of the EuropeanUnion the cost of mental health prob-lems is estimated to be between 3%and 4% of GNP (ILO, 2000), of whichhealth-care costs account for an aver-age of 2% of GNP.

• For the United States Rice and col-leagues calculated an aggregate costof US$ 148 billion (at 1990 prices)for all mental disorders. One of themost important findings is that theindirect costs either match or out-weigh the direct costs for all mentalhealth areas. Spending on treatmentfor mental health and substanceabuse in the United States alone wasestimated at US$ 85.3 billion in1997: US$ 73.4 billion for mental illness and US$ 11.9 billion for sub-stance abuse (Mark et al., 2000).

• The estimated total burden of men-tal health problems in Canada for1998 was at least Can$ 14.4 billion:Can$ 8.1 billion in lost productivityand Can$ 6.3 billion for treatments(Stephens & Joubert, 2001). Thismakes mental health problems oneof the costliest conditions in Canada.

• Patel and Knapp (1997) estimatedthe aggregate costs of all mentaldisorders in the United Kingdom at£32 billion (1996/97 prices), 45% ofwhich was due to lost productivity.

How much does mental illness cost?

Mental disorders impose a range of costs onindividuals, households, employers andsociety as a whole.

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Mental health problems in childhood generate additional costs in adulthood

4

0

10 000

20 000

30 000

40 000

50 000

60 000

70 000

80 000

Costs in adulthood of childhood mental health problemsAdditional costs from 10-27 years (in £)

Criminal justice

Benefits

Relationships

Social care

Health

Education

Source: Knapp, 2003

No problems Conduct problems Conduct disorder

The costs of childhood disorders canbe both large and largely hidden(Knapp et al., 1999). Early onset ofmental disorders disrupts educationand early careers (Kessler et al., 1995).The consequences in adulthood canbe enormous if effective treatment isnot provided (Maughan & Rutter,

1998). Knapp shows in figure 4 thatchildren with conduct disorders gener-ate substantial additional costs fromages 10 to 27 years. These are notmainly related to health, as one wouldexpect, but to education and criminaljustice, creating a serious challenge forthe social capital as a whole.

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comparatively high annual expendi-ture associated with chronic diseaseconditions such as psychosis and neu-rosis (NHS Executive, 1996; Figure 5below).

17

A recent comparative study of theburdens of disease carried out withinthe United Kingdom’s National HealthService (NHS) demonstrated the rela-tive and absolute costs of care for awide range of disorders, including the

High costs of mental disorders compared to other major chronic conditions

5

0 200 400 600 800 1000 1200

NHS burdens of disease, 1996£ million, 1992/93

Inpatient

Outpatient

Primary care

Pharmaceuticals

Community health

Social services (adults)

Source: NHS Executive, 1996

Psychosis

Neurosis

Diabetes

Breast cancer

Ischaemic Heart Disease

Hypertension

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6

0

20

40

60

80

100

120

Prevalence and cost of major chronic conditions: United States

(in millions)

Alzheim

er

arth

ritis

asth

ma

canc

er

CHF

CHD

depr

essio

n

diabe

tes

hype

rtens

ion

oste

opor

osis

schiz

ophr

enia

strok

e

CHF: congestive heart failure

CHD: coronary heart disease

cost (US$ '000)

prevalence (n° patients)

Source: Berto et al., 2000

Another recent study (Berto et al.,2000) presents prevalence and totalmanagement costs of diseases such asAlzheimer’s, asthma, cancer, depres-sion, osteoporosis, hypertension andschizophrenia. As shown in figure 6

for the United States, three mentaldisorders considered by Berto et al.(Alzheimer’s disease, depression andschizophrenia) present a high preva-lence-cost ratio.

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Even more interesting is to considerdifferent diseases in terms of the aver-age cost per patient, as shown in fig-ure 7: Alzheimer’s disease andschizophrenia are the two most costlydiseases, their average cost per patientbeing higher than cancer and stroke.

19

In the United States, mental illness isconsidered responsible for an estimat-ed 59% of the economic costs deriv-ing from injury or illness-related lossof productivity, followed by alcoholabuse at 34% (Rouse, 1995). A reportfrom a Canadian university (UniversitéLaval, 2002) revealed that absencesfor psychological reasons had

increased 400% from 1993 to 1999,and that the costs of replacement,together with those of salary insur-ance, amounted to Can$ 3 million forthe year 2001. A survey on psychiatricmorbidity in the United Kingdomshowed that people with psychosistook an average of 42 days a year offwork. The same survey reveals that

In many developed countries, 35% to 45% of absenteeism from work is due to mental health problems

7

0

5000

10000

15000

20000

25000

Yearly cost per patient of selected major conditions: United States

US$/patient/year

Alzheim

erar

thrit

isas

thm

aca

ncer

CHF

CHDde

pres

sion

diabe

tes

hype

rtens

ionos

teop

oros

issc

hizop

hren

ia

strok

e

Source: Berto et al., 2000

CHF: congestive heart failure

CHD: coronary heart disease

persons with two or more neuroticdisorders had an average of 28 daysoff per year compared to 8 days offfor those with one neurotic disorder(Patel & Knapp, 1997).

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A recent study from Harvard MedicalSchool examined the impact of psy-chiatric disorders on work loss days(absence from work) among majoroccupational groups in the UnitedStates (Kessler & Frank, 1997). Theaverage number of work loss daysattributable to psychiatric disorderswas 6 days per month per 100 work-ers; and the number of work cutbackdays (getting less done than usual)was 31 days per month per 100 work-

Decreased productivity at work: even if an employee does not take sick leave, mental health problems can result in a substantial reduction in the usual level of activity and performance

Phot

o: ©

WH

O, P

. Viro

t

ers. Although the effects on work losswere not significantly different acrossoccupations, the effects on work cut-back were greater among professionalworkers. Work loss and cutback werefound to be more prevalent amongthose with comorbid disorders thanamong those with single disorders.The study presents an annualizednational projection of over 4 millionwork loss days and 20 million workcutback days in the United States.

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The special case of depression

The burden of depression is rising, affecting both the working and social lives

of individuals.

In the United States, it has been estimated that 1.8% to 3.6% of workers

suffer from a major depression, and that employees with depression are

disabled at nearly twice the rate of persons without depression (Goldberg

& Steury, 2001). In 2000, 7.8 million Canadians were treated for depression,

which represents an increase of 36% compared to the previous year.

In a large United States financial services company, depression resulted in an

average of 44 work-days taken off for short-term disability as compared to

42 days for heart disease, 39 days for lower back pain, and 21 days for asth-

ma (Conti & Burton, 1994). Studies suggest that the average annual costs,

including medical, pharmaceutical and disability costs, for employees with

depression may be 4.2 times higher than those incurred by a typical benefi-

ciary (Birnbaum & al., 1999). However, it has also been found that the cost

of treatment for depression is completely offset by a reduction in the number

of days of absenteeism. Moreover, it is demonstrated that the cost of achiev-

ing a partial or full remission from major depression declined between 1991

and 1996.

If the burden of depression is rising, costs to treat it are declining, and the

quality of care has been improving over time. Specific investments to prevent

and cure major depression can and should be made in both developed and

developing countries.

Mental illness affects access to the job market and job retention

In the United States 5–6 million work-ers between the ages of 16 and 54years either lose, fail to seek, or cannotfind employment as a consequence ofmental illness. Among those who domanage to find work, it has been esti-mated that mental illness decreasesannual income by US$ 3500 toUS$ 6000 (Marcotte & Wilcox-Gok,2001).

In the United Kingdom, a 1995 sur-vey revealed that over half of thepeople with psychosis were classed aspermanently unable to work, about afifth were in employment and one ineight was unemployed (Patel &Knapp, 1997).

Individuals with comorbid mental and physical disorders consistentlyhave lower rates of employment than persons with a physical disorderalone. In several surveys, approxi-mately 20% fewer individuals withboth physical and mental disordersreported being employed than indi-viduals with only a physical disorder(McAlpine & Warner, 2002).

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The burden of substance abuse

• 76.3 million persons are diagnosedwith alcohol disorders;

• At least 15.3 million persons areaffected by disorders related to druguse;

• Between 5 and 10 million peoplecurrently inject drugs;

• 5%–10% of all new HIV infectionsglobally result from injecting drugs;

• More than 1.8 million deaths in2000 were attributed to alcohol-related risks;

• 205,000 deaths in 2000 wereattributed to illicit drug use (Figure 8);

• The government, drug abusers andtheir families shoulder the main eco-nomic burden of drug abuse; and

• For every dollar invested in drugtreatment, seven dollars are saved inhealth and social costs.

Abuse of alcohol and other substancescontinues to be one of the most seriouspublic health problems in both devel-oped and developing countries. World-wide, alcohol accounted for 4% of thetotal burden of diseases in 2000.

In Latin American countries, alcoholwas the leading risk factor for theglobal burden of diseases in 2000. Ofan estimated 246,000 alcohol-relateddeaths in this region, about 61,000were due to unintentional and inten-tional injuries (WHO, 2002), all of

which could have been prevented.Alcohol abuse is also responsible forneuropsychiatric disorders, domesticviolence, child abuse and neglect, andproductivity loss.

In South Africa, 25%–30% of generalhospital admissions are directly or indi-rectly related to alcohol abuse (Alber-tyn & McCann, 1993), and 60%–75% of admissions in specialized sub-stance abuse treatment centres are foralcohol-related problems and depen-dence. Almost 80% of all assaultpatients (both males and females) presenting to an urban trauma unit inCape Town were either under theinfluence of alcohol, or injuredbecause of alcohol-related violence(Steyn, 1996). The majority of victimsof train-related accidents, traffic acci-

dents – both pedestrians and drivers –had blood alcohol levels exceeding thelegal limits (Van Kralingen et al, 1991).Foetal alcohol syndrome is by far themost common cause of mental disabil-ity in the country (Department ofTrade and Industry, 1997).

In Asia, substance abuse is consideredthe main cause in 18% of cases pre-senting problems in the workplace(EAP, 2002). In Thailand, the percent-age of substance abusers aged 12–65years varies from 8.6% to 25% in different regions of the country, thehighest percentage being in the north-east. In New Zealand (with a popula-tion of 3.4 million) alcohol-related lostproductivity among the working pop-ulation was estimated to be US$ 57million a year (Jones et al., 1995).

8

0 500 1000 1500 2000

Deaths in 2000 attributed to addictive substance abuse-related risks

High mortality developing countries

Low mortality developing countries

Developed countries

Alcohol

Illicitdrugs

Number of deaths (000s)

Source: WHO, 2002

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9

0

30

60

90

120

150

Cost of alcohol abuse in USA, billion US$, 1998

lost productivity

health care vehicle crashes criminal justice system

Source: Harwood, 2000

In the United States, the total eco-nomic cost of alcohol abuse was esti-mated at US$ 185 billion for 1998(Harwood, 2000). More than 70% of this cost was attributed to lost pro-ductivity (US$ 134.2 billion), includinglosses from alcohol-related illness(US$ 87.6 billion), premature death(US$ 36.5 billion) and crime(US$ 10.1 billion). Health care expen-ditures accounted for US$ 26.3 billion,of which US$ 7.5 billion was spent ontreating alcohol abuse and depen-dence and US$ 18.9 billion on treatingthe adverse medical consequences ofalcohol consumption. Other estimatedcosts included property and adminis-trative costs due to alcohol-relatedautomobile crashes (US$ 15.7 billion),and the costs of the criminal justicesystem for alcohol-related crime(US$ 6.3 billion) (Figure 9).

In the United Kingdom, about150,000 people are admitted to hos-pital each year due to alcohol-relatedaccidents and illnesses. Alcohol isassociated with up to 22,000 deaths a year. Deaths from cirrhosis of theliver have nearly doubled in the last10 years. A recent government reportshows that alcohol abuse costs thecountry at least £20 billion a year. The study found that 17 million work-

days are lost to hangovers and alcohol-related illnesses each year. This costsemployers £6.4 billion. One in 26 NHS“bed days” is taken up by alcohol-related illness, resulting in an annualcost to the taxpayer of £1.7 billion.The cost of clearing up alcohol-relatedcrime is a further £7.3 billion a year.Moreover, drink leads to a further £6 billion in “social costs”.

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10

Excessive alcohol consumption and impaired health of the family

Excessive

alcohol

consumption

More money is spent on alcohol

Less income, more loans

Sickness, absenteeism, job loss

Minor convictions

Accidents and injuries

Gambling

Less food, less education

Poor living conditions

Wife and children have to work

Less health care

Social stigma

Financial

problems

Health

of family

members

Malnutrition

Infections like TB, worm infestation

Stunted development of children

Diseases related to alcohol and sub-stance abuse are therefore a seriouspublic problem. They affect develop-ment of the human and social capital,creating not only economic costs for

society as a whole, including thehealth system, but also social costs interms of injuries, violence and crime.They also affect the well-being offuture generations (Figure 10).

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Since mental disorders generate costsin terms of long-term treatment andlost productivity, it can be argued thatsuch disorders contribute significantlyto poverty. At the same time, insecuri-ty, low educational levels, inadequatehousing and malnutrition have allbeen recognized as contributing tocommon mental disorders. There isscientific evidence that depression is1.5 to 2 times more prevalent amongthe low-income groups of a popula-tion. Poverty could therefore be con-sidered a significant contributor tomental disorders, and vice-versa. The two are thus linked in a viciouscircle (Figure 11), and affect severaldimensions of individual and socialdevelopment:

Work

Unemployed persons and those whofail to gain employment have moredepressive symptoms than individualswho find a job (Bolton & Oakley,1987; Kessler & al., 1989; Simon & al.,2000). Moreover, employed personswho have lost their jobs are twice aslikely to be depressed as persons whoretain their jobs (Dooley & al., 1994).

Education

Studies have shown a significant rela-tionship between the prevalence ofcommon mental disorders and loweducational levels (Patel & Kleinman,2003). Moreover, a low educationallevel prevents access to most profes-sional jobs, increases vulnerability andinsecurity and contributes to a persis-tently low social capital. Illiteracy andillness therefore lock in poverty.

Violence and trauma

In communities afflicted by poverty,violence and abuse are not unusual.They affect general mental well-being,and can induce mental disorders in themost vulnerable.

Without well-targeted and structuredinvestment in mental health, thevicious circle of poverty and mentaldisorders will be perpetuated, therebypreventing poverty alleviation anddevelopment.

Talking about mental disorders means talking about poverty: the two are linked in a vicious circle

11

Poverty and mental disorders: a vicious circle

Suicide

Alcohol

Depression

Substance Abuse

Child/adolescent development problems

Post traumatic stress disorders

Poverty

Physical disorders

Mental disorders

Violence and trauma

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In order to reduce the increasing burden of mental disorders and avoidyears lived with disability or death,priority should be given to preventionand promotion in the field of mentalhealth. Preventive and promotionalstrategies can be used by clinicians to target individual patients, and by public health programme planners to target large population groups.

Within the spectrum of mentalhealth interventions, prevention andpromotion have become realistic andevidence based, supported by a fast-growing body of knowledge fromfields as divergent as developmentalpsychopathology, psychobiology,

prevention, and health promotionsciences (WHO, 2002). Preventionand promotion programmes havealso been shown to result in consid-erable economic savings to society(Rutz et al., 1992).

Integrating prevention and promotionprogrammes for mental health withinoverall public health strategies willhelp to avoid deaths, reduce the stig-ma attached to the persons with men-tal disorders and improve the socialand economic environment.

Is it possible to promote mental health and prevent mental disorders?

Promoting mental health; preventing and managing mental ill health

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Much can be done to reduce the burdens ofmental disorders, avoid deaths and promotemental health in the world.

Mental health promotion

Health promotion is the process ofenabling people to gain increasingcontrol over their health and improveit (WHO, 1986). It is therefore relatedto improving the quality of life andthe potential for good health, ratherthan only an amelioration of symp-toms (Secker, 1998). Psychosocial factors influence a number of healthbehaviours (e.g. proper diet, adequateexercise, and avoiding cigarettes,drugs, excessive alcohol and risky sex-ual practices) that have a wide-rang-ing impact in the domain of health(WHO, 2002).

A growing body of cross-cultural evi-dence indicates that various psycho-logical, social and behavioural factorscan protect health and support posi-tive mental health. Such protectionfacilitates resistance (resilience) to dis-ease, minimizes and delays the emer-gence of disabilities and promotesmore rapid recovery from illness(WHO, 2002). The following studiesare illustrative. Breast-feeding (advo-cated by the joint WHO/UNICEFBaby-Friendly Hospital Initiative, Naylor, 2001) improves bonding andattachment between infants and

mothers, and significantly improveschild development. Promotive inter-ventions in schools improve self-esteem, life skills, pro-social behaviour,scholastic performance and the overallclimate.

Among various psychosocial factorslinked to protection and promotion inadults are secure attachment; an opti-mistic outlook on life, with a sense ofpurpose and direction; effective strate-gies for coping with challenge; per-ceived control over life outcomes;emotionally rewarding social relation-ships; expression of positive emotion;and social integration.

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When can interventions for prevention of mental disorders begin?

Visits by nurses and community work-ers to mothers during pregnancy andafter childbirth, in order to preventpoor child care, child abuse, psycho-logical and behavioural problems inchildren and postnatal depression inmothers, have proved to be extremelyeffective on a sustainable basis (Oldset al., 1988). Teaching mothers aboutearly monitoring of growth and devel-opment in low-birth-weight babies,along with proper maternal advice,can prevent poor intellectual develop-

ment (Infant Health and DevelopmentProgramme, 1990). Early stimulationprogrammes can enable mothers toprevent the slow development oftenseen in preterm infants, and improvethe physical growth and behaviour ofsuch infants (WHO, 1998). Such pro-grammes can also reduce the numberof days spent in hospital (Field et al.,1986), and thus result in economicsavings. Nutrient supplements to pre-vent neuropsychiatric impairmenthave also been found to be useful.

For example, iodine supplementationprogrammes through iodination ofwater or salt (recommended by WHO,1996; 2001) can help prevent cre-tinism and other iodine-deficiency dis-orders (Sood et al., 1997; Mubbashar,1999). Moreover, it may have a posi-tive effect on the intelligence level ofeven apparently healthy populationsliving in iodine-deficient areas (Ble-ichrodt & Born, 1994).

Preventive interventions reducedepression and feelings of hopeless-ness, aggressive and delinquentbehaviour, as well as alcohol, tobaccoand drug use, on a sustained basis(Schweinhart & Weikart, 1992; WHO,1993; Bruene-Butler et al, 1997;Shochet et al, 2001).

Training teachers and parents hasbeen shown to improve detection ofproblems and facilitate appropriateinterventions.

Preventive strategies are useful even during childhood and adolescence

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A stitch in time

Psychosocial interventions, such ascognitive-behavioural therapy andfamily-based group intervention for“high risk” children, prevent thedevelopment of anxiety disorders(Dadds et al., 1997) and reducedepressive symptoms and conductproblems (Jaycox et al., 1994).Depression in adolescence has a highrisk of recurrence in adulthood, and isalso associated with the risk of devel-opment of personality problems orconduct disorders.

It is possible to prevent the majority of suicides and suicide attemptsamong schoolchildren through a com-prehensive schools-based preventionprogramme that includes appropriatemodifications to school-based policy,teacher training, parent education,stress management and a life-skillscurriculum, along with the introduc-tion of a crisis team in each school(Zenere & Lazarus, 1997).

Vel

iana

, 6 y

ears

old

, Bul

garia

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There is considerable evidence whichshows that preventive strategiesimprove marital, relational and occu-pational functioning. It is possible toreduce dysfunctional marital commu-nication, sexual difficulties, divorceand child abuse among young couplesthrough education and skills training(Renick et al., 1992; Cowan & Cowan,1992). Programmes to cope with wid-owhood and bereavement have beenseen to help reduce depressive symp-toms and facilitate better adjustment(Vachon et al., 1980). Similarly, studieshave shown that stress-managementskills and occupational stress-manage-ment training for personnel at risk(e.g. nursing personnel, bus drivers,teachers and blue collar workers) canbe very useful. It has also be seen thatretrenched workers who received ade-quate counselling coped better, hadfewer depressive symptoms and man-aged to find better jobs (Vinokur etal., 1992). Retrenchment and job losscan cause depression, anxiety andmany other problems such as alco-holism, marital stress and child abuse,and can even can lead to suicide.

Physician advice and other forms ofbrief intervention have been found tobe effective in reducing alcohol abuse(Babor & Grant, 1992). Brief interven-tions have also been tried to reducesmoking (Kottke et al., 1988). Strate-gies to prevent alcohol and other sub-stance abuse through masscampaigns, including the use of alco-hol warning labels, have been success-ful in raising awareness (MacKinnonet al., 2000). Similarly, community-intervention programmes aimed atwomen, that involve community coali-tions, task forces and support groups,help reduce smoking (Secker-Walkeret al., 2000).

The introduction of mandatory bicyclehelmet use leads to a substantialreduction in head injuries that cancause neurological and mental disabili-ties (Cameron et al., 1994). Short cog-nitive-behavioural programmes forvictims of vehicular and industrial acci-dents (Fecteau & Nicki, 1999; Bryantet al., 1998) are beneficial in the pre-vention and management of post-traumatic stress disorder.

How can prevention help adults and the elderly?

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The prevention of suicidal behaviour(both attempted and completed sui-cide) poses a series of particular chal-lenges at the public health level. Onthe one hand, subjects at risk of suici-dal behaviour cover a wide age range,from early adolescence to later life.On the other hand, the risk of suicidalbehaviour varies greatly according toseveral sociocultural factors (amongwhich age, gender, religion, socioeco-nomic status) and mental status.

It is also influenced by the availabilityof methods used for that behaviour.This diversity calls for an integration ofdifferent approaches at the populationlevel in order to achieve significantresults.

According to the best evidence avail-able (WHO, 1998), the followinginterventions have demonstrated effi-cacy in preventing some forms of sui-cidal behaviour:

• Control of availability of toxic sub-stances (particularly pesticides inrural areas of some Asian countries);

• Detoxification of domestic gas andcar exhaustion;

• Treatment of people with mentaldisorders (particularly depression,alcoholism and schizophrenia);

• Reduction of access to firearms; and

• Toning down of press reports aboutsuicides.

Prevention of suicidal behaviour

Hoa

ng G

ia, 9

yea

rs o

ld, V

ietn

am

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The widening recognition of mentalhealth as a significant internationalpublic health issue has led to thegrowing need to demonstrate thatinvestment of resources in servicedevelopment is not only required, but also worthwhile. Specifically, it is important to collect evidence ofeffective and appropriate mentalhealth care strategies that are also

cost-effective and sustainable.Although the volume of completedstudies remains modest, particularly in middle- and low-income countries,there is increasing economic evidenceto support the argument that inter-ventions for schizophrenia, depressionand other mental disorders are notonly available and effective, but arealso affordable and cost-effective.

Treatment of mental disorders: effectiveness and cost-effectiveness

12

0%

10%

20%

30%

40%

50%

Treatment effects on disability

Percent total improvement in disability

Schizophrenia Bipolar disorder Depression Panic disorder

Psychosocial effect

Drug effect

Placebo effect

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There is considerable literature con-cerning the efficacy and effectivenessof a wide range of pharmacological,psychosocial and care managementstrategies for treating both psychiatricdisorders and addiction. Figure 12 onopposite page illustrates the reductionin disability following pharmacologicaland psychosocial treatment, alone orin combination. As can be seen, theextent of improvement over no treat-ment at all is as much as 50%. Thus,while currently available interventionsdo not completely cure the disabilityassociated with these conditions, theyhave a substantial advantage over notreatment at all, which unfortunately,is often the case. This raises the ques-tion of the costs involved in realizingthese health improvements.

Figure 13 illustrates the effectivenessof treatment, provided through com-munity outreach care (low-cost drugtherapy and basic psychosocial sup-port), on the economic burden anddisability of untreated schizophrenia in India; not only did disabilityimprove dramatically, but the overallcosts associated with the condition(which included care-giving time byfamily members) also fell. Theseeffects were sustained over an 18-month follow-up period.

How effective are treatments for burdensome psychiatric conditions?

13

0 3 6 9 12 15 180

10

20

30

40

50

60

Changes in disability following community outreach treatment of untreated schizophrenia in rural India

WH

OD

AS

II di

sabi

lity

scor

e

Follow-up assessment (months)

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WHO has embarked upon the world-wide collection of such an evidencebase by means of its WHO-CHOICEproject, including estimation of thecost and efficiency of a range of keytreatment strategies for burdensomemental disorders. Figure 14 below

34

a more evidence-based approach tomental health budgetary planning,resource allocation and service devel-opment represents an underdevelopedbut much needed component ofnational mental health policy in devel-oping regions of the world.

The alarmingly low level of resourcesavailable in developing countries totreat mental health problems, relativeto the affected population for whichthe resources are needed, has beenhighlighted by the WHO ATLAS pro-ject (WHO, 2001). The generation of

What are the costs of effective treatment?

14

0 500 1000 1500 2000 2500

The annual cost per case (or episode) of evidence-based psychiatric treatment

Cost per treated case (in international dollars, I$)

Africa

Latin America

Middle East

Eastern Europe

SE Asia

W Pacific

SchizophreniaOlder anti-psychotic drug+psychosocial treatment

Bipolar disorder:Mood stabiliser drug+psychosocial treatment

Depression:Older anti-depressant drug +proactive care

Panic disorder:Older anti-depressant drug+psychosocial treatment

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Cost-effectiveness should be just one of several criteria used in the decision-

making process for funding prevention/treatment of mental disorders.

These economic evaluations should be supplemented by other arguments.

For example:

• People with mental disorders are more at risk of human rights violations

and are more likely to be discriminated against in accessing treatment and

care;

• Achievement of physical health targets, such as:

– Infant and child mortality can be reduced through improved treatment

of postnatal depression;

– HIV/AIDS infection rates for the 17-24 year-old age group are reduced

because improved mental health reduces unsafe sex and drug use;

– There is better adherence to treatments for other ailments (e.g. tubercu-

losis, HIV/AIDS, hypertension, diabetes and cancer treatments);

• Caregivers benefit from a lower burden of care, which means better quality

of life and fewer work days lost, and thus less loss of income;

• Employers benefit from better working environment, reduced absenteeism

and higher productivity;

• Governments benefit from less cost-shifting and transfer payments;

• Mental health is a key variable in successful programmes for sustainable

development and poverty reduction.

shows the estimated cost of first-linetreatment of schizophrenia and bipo-lar disorder on a hospital outpatientbasis, and also the cost of primarycare of depression and panic disorder,based on estimated use of health careresources that would be required toproduce the expected reduction in dis-ability. Costs are expressed in interna-tional dollars (I$), which take intoaccount the purchasing power of dif-ferent countries. It is clear that moresevere psychiatric conditions such asschizophrenia require substantiallygreater resource inputs (mainlybecause a proportion of cases need tobe hospitalized or provided with resi-dential care outside hospital). By con-trast, the cost of effectively treating anepisode of depression is estimated tobe in the region of I$ 100–150.

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Even though mental, brain and sub-stance-use disorders can be managedeffectively with medication and/orpsychosocial interventions, only asmall minority of patients with mentaldisorders receives even the most basictreatment. Initial treatment is fre-quently delayed for many years. Indeveloped countries with well-orga-nized health care systems, between44% and 70% of patients withdepression, schizophrenia, alcohol-usedisorders and child and adolescentmental illnesses do not receive treat-ment (Figure 15) in any given year. In developing countries, where thetreatment gap is likely to be closer to90% for these disorders, most individ-uals with severe mental disorders areleft to cope as best they can.

More than 40% of all countriesworldwide have no mental health policy and over 30% have no mentalhealth programme. Over 90% ofcountries have no mental health policythat includes children and adolescents.Out-of-pocket expenditure was theprimary method of financing mentalhealth care in many (16.4%) coun-tries. Even in countries where insur-ance cover is provided, health plansfrequently do not cover mental andbehavioural disorders at the samelevel as other illnesses; this creates significant economic difficulties forpatients and their families.

The gap between the burden ofmental disorders and resources

15

0

20

40

60

80

100

Treatment gap rates (%) by disorder (world)

Schizophrenia

Treated

Untreated

Child/adolescentmental disorders

Majordepression

Alcohol usedisorder

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In spite of the importance of a sepa-rate mental health budget within theoverall health budget, 32% of coun-tries included in the ATLAS study(WHO, 2001) reported not having aspecific governmental budget formental health. Of those that actuallyreported having one, 36.3% spentless than 1% of their total health budget on mental health. Countriescategorized on the basis of incomelevels (World Bank classification) differ

considerably in terms of the propor-tion of their governmental budget formental health to their total healthbudget (Figure 16). The poorer coun-tries have small health budgets, fromwhich they spend a lower percentageon mental health, resulting in very fewresources being available. Poor provi-sion of mental health care results inpoor outcomes, avoidable relapsesand insufficient rehabilitation.

Mental health budget in low-income countries: non-existent or inadequate

16

0%

20%

40%

60%

80%

100%

Share of mental health budget in total health budgetof countries by income level (%) (World Bank classification)

Total Health Budget

Mental Health Budget

Low income Low MiddleIncome

Higher MiddleIncome

High Income

1.54 2.78 3.496.89

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Mental and behavioural disorders areestimated to account for 13% of theglobal burden of disease, yet, on aver-age, the mental health budgets ofcountries constitute only 2% of theirtotal health expenditures (Figure 17).

A wide gap between the burden of neuropsychiatric disorders and the mental health budget

The relationship between the burden ofmental disorders and spending is clearlyinappropriate.

17

0%

3%

6%

9%

12%

15%

13%

2%

Burden of neuropsychiatric disorders vs budget

Burden ofneuropsychiatric disorders

as a percentage of all disorders

Median mental health budget as a percentage

of total government health budget

Phot

o: ©

A. M

ohit

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Urgent action is needed to close thetreatment gap and to overcome barriers whichprevent people from receiving appropriatecare.

There are several barriers to people’s access to appropriate mental health care

Stigma

Around the world, many people withmental disorders are victimized fortheir illness and become the targets ofunfair discrimination. Access to hous-ing, employment and normal societalopportunities is often compromised.

Discrimination in insurancecoverage for mental disorders

In many countries, since mental disor-ders are not covered by health insur-ance schemes, many people cannotafford treatment. One-quarter of allcountries do not provide disabilitybenefits to patients with mental disor-ders. One-third of the world’s popula-tion – 2 billion people – lives incountries that spend less than 1% oftheir health budgets on mental health.

Lack of drugs

Though 85% of countries have anessential drugs list that countries useas a basis for procuring therapeuticdrugs, almost 20% of countries donot have at least one common anti-depressant, one antipsychotic, andone antiepileptic in primary care.

Wrong priorities

Too many countries (mainly developedcountries) still spend most of theirresources on a few large mental asy-lums, which focus only on a smallfraction of those who need treatment;even these institutions generally pro-vide poor quality care and often inhu-mane conditions and treatment.

Lack of skills at the primaryhealth care level

Too few doctors and nurses knowhow to recognize and properly treatmental disorders. In 41% of countriesthere are no mental health trainingprogrammes for primary health careprofessionals.

Lack of rational andcomprehensive mental healthpolicies and legislation

• 40% of countries do not have a mental health policy;

• 25% of countries do not have mental health legislation; and

• 30% of countries do not have anational mental health programme.

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WHO declared 2001 the Year of Men-tal Health and that year’s WorldHealth Day was a resounding success.Over 150 countries organized impor-tant activities, including major speech-es by political leaders and theadoption of new mental health legisla-tion and programmes.

At the 2002 World Health Assembly,over 130 Ministers responded posi-tively with a clear and unequivocal

message: mental health, neglected fortoo long, is crucial to the overall well-being of individuals, societies andcountries, and must be universallyregarded in a new light. The theme ofthe World Health Report 2001 wasmental health, and its 10 recommen-dations have been positively receivedby all Member States.

As a result of the activities in 2001,the Mental Health Global Action Pro-gramme (mhGAP) has been created.mhGAP is WHO’s major new effort toimplement the recommendations ofthe World Health Report 2001. Theprogramme is based on four strategies(Figure 18) that should help enhancethe mental health of populations.

Year of Mental Health: 2001

WHO Global Action Programme(mhGAP)

18

Mental Health Global Action Programme (mhGAP):the four core strategies

Increased

country

capacity

Enhanced

mental

health

services

Reduced

stigma and

discrimination

Information

for better

decisions

Advocacy

against

stigma and

discrimination

Integrated

policy and

service

development

Reduced

disease

burden

Enhanced

mental

health of

populations

Enhanced

public health

research

capacity

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Strategy 1

Increasing and improving information for decision-making and tech-

nology transfer to increase country capacity.

WHO is collecting information about the magnitude and the burden of mental

disorders around the world, and about the resources (human, financial, socio-

cultural) that are available in countries to respond to the burden generated by

mental disorders. WHO is disseminating mental health-related technologies

and knowledge to empower countries in developing preventive measures and

promoting appropriate treatment for mental, neurological and substance-

abuse disorders.

Strategy 2

Raising awareness about mental disorders through education and

advocacy for more respect of human rights and less stigma.

The World Health Organization is establishing the first all-inclusive global

partnership of mental health-related constituencies: the Global Council for

Mental Health. It will act as a forum for mental health, stimulating and lend-

ing support to activities aimed at promoting implementation of the 10 rec-

ommendations of the World Health Report 2001 in all regions. Professional

NGOs, family members and consumer groups, leaders of religious groups,

parliamentarians, labour and business organizations are all enthusiastic about

pursuing activities for the improvement of mental health through this com-

mon platform led by WHO.

Advocacy, information, policy and researchare the key words underlying WHO’s newglobal mental health programme, which aimsat closing the gap between those who receivecare and those who do not.

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Strategy 3

Assisting countries in designing policies and developing comprehensive and effective mental health ser-

vices. The scarcity of resource forces their rational use.

The World Health Report 2001 and the Atlas: Mental Health Resources in the World, have revealed an unsatisfactory

situation with regard to mental health care in many countries, particularly in developing countries. WHO is engaged in

providing technical assistance to Ministries of Health in developing mental health policy and services. Building national

capacity is a priority to enhance the mental health of populations.

WHO has designed a mental health policy and service guidelines to address the wide variety of needs and priorities in

policy development and service planning, and a manual on how to reform and implement mental health law.

To put plans into action, WHO is adapting the level and types of implementation to the general level of resources of

individual countries. In the particular case of developing countries, where the gap between mental health needs and the

resources to meet them is greater, WHO will offer differentiated packages of “achievable targets” for implementation

(Gap Reduction Achievable National Targets/GRANTs) to countries grouped by at least three levels of resources (low,

middle and relatively higher). These packages provide the minimum required set of feasible actions to be undertaken to

comply with the 10 recommendations spelt out in the World Health Report 2001. Achievement of the identified targets

will influence both health and social outcomes, namely mortality due to suicide or to alcohol/illicit drugs, morbidity and

disability due to the key mental disorders, quality of life, and, finally, human rights.

Strategy 4

Building local capacity for public mental health research in poor countries.

Besides advocacy, policy assistance and knowledge transfer, mhGAP formulates in some detail the active role that infor-

mation and research ought to play in the multidimensional efforts required to change the current mental health gap at

country level.

WHO is developing several projects and activities to promote this strategy at country level, including a research fellow-

ship programme targeting developing countries. A project on the cost-effectiveness of mental health strategies is being

implemented in selected countries to generate real estimates on the costs and benefits of mental health interventions.

These estimates will then be used to enhance mental health services at country level.

At the Executive Board meeting in January 2002 a resolution onmental health encouraging continued activity in this area wasadopted. The resolution strongly supports the direction of mhGAPand urges action by Member States. The resolution was endorsedunanimously by the World Health Assembly in May 2002.

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Interventions can be implementedimmediately and widely with existingknowledge and technology. Thereturns in terms of reducing disabilityand preventing premature death areenormous.

Prevention of childhood mentalproblem

Mother & child careAdequate care during pregnancy andaround childbirth prevents brain andmental disorders. Early childhood socialstimulation also ensures better psy-chosocial development and preventsemotional and conduct disorders.

School-based programmesPsychosocial interventions by teachersand counsellors can prevent depres-sion, aggressive behaviours and sub-stance abuse among students.

Suicide prevention

Media interventionsMental health professionals can initiatecodes of conduct for the mass mediato ensure that they do not glamorizeinstances of suicide, so as to preventfurther suicides in communities.

Restriction of means to commit suicideIt has been demonstrated that restric-tions on the availability of means tocommit suicide (e.g. pesticides) can beeffective in their prevention. Laws andregulations could curb the availabilityof dangerous substances.

Prevention of alcohol-relatedproblems

Higher taxationHigher taxes on alcoholic beveragesuniformly bring down the consump-tion levels, leading to substantialreduction in alcohol-related problems.

Brief interventionsModels of brief interventions appliedwithin primary health care settings haveproved to be effective for most peoplewith alcohol-related problems (25%reduction in alcohol consumption).

Depression

Early identification of people sufferingfrom depressive disorders We know that even in high-incomecountries almost 50% of those suffer-ing from depression are not identified.Early identification means more effec-tive treatment and avoidance of dis-ability and death by suicide.

Care in primary health servicesDepressive disorders can be effectivelytreated, in most instances, with com-mon and inexpensive medicines andsimple psychosocial interventions. Thisis possible within primary health ser-vices with the provision of some basictraining and appropriate medicines.

Much can be done; everyone cancontribute to better mental health

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Schizophrenia

Maintenance on antipsychoticmedicinesOnce this disorder is diagnosed andtreatment is begun, most patientsneed continued follow-up and regularmedicines. This costs very little, butresults in substantial reduction in dis-ability and improvement in quality oflife.

Involvement of family in careFamilies are the most significant part-ners in the care of chronic mental dis-orders. Simple interventions deliveredto the families can enhance the qualityof life both of the patient and of thewhole family. And relapse can be pre-vented.

Mental retardation

Iodinization of saltUsing iodized salt is the single mosteffective prevention activity in areasdeficient in iodine. Millions of childrencan escape long-lasting intellectualdeficits by this most inexpensive pub-lic health measure.

Training to parentsParents can help children with mentalretardation to achieve their full poten-tial for development. Simple trainingto parents can go a long way in ensur-ing the best environment for childrenwith mental retardation.

Epilepsy

Anti-stigma campaignsThe biggest barrier to treatment forepilepsy is stigma. Campaigns againststigma result in a larger proportion ofthose affected getting much-neededtreatment as well as reintegration intoschools and their communities.

Availability of medicinesAntiepileptic medicines cost very little,but their availability within health careservices is limited. Ensuring regularavailability of these medicines makestreatment possible, even in the poorest countries: up to 70% of newly diagnosed cases can be successfully treated.

Human rights

Legislation should be modernized.Monitoring of human rights violationsshould be put in place. Quality ofbasic care in psychiatric settingsshould be improved. All this willensure a better quality of life andmore dignity for patients. A substan-tial component of interventions formental disorders is that of enablingpatients to fully enjoy their rights ofcitizenship.

44

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Everyone can contribute

Individuals

Foundations

Communities

Mental healthprofessionalsPolicy makers

and governments

MediaNGOs

Private sector

Families

Scienceinstitutions

MentalHealth

Everyone can contribute

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Department of Mental

Health and Substance

Dependence

WHO Regional Office for Africa

Cité du DjouéPO Box 06 BrazzavilleCongo

Tél: +47 241 39100+242 8 39100

Fax: +47 241 39501+242 8 39501

E-mail: [email protected]

Pan American HealthOrganization/WHORegional Office for theAmericas

525, 23rd Street, NWWashington, DC 20037USA

Tel: +1 202 974 3000Fax: +1 202 974 3663

E-mail: [email protected]

WHO Regional Office for the Eastern Mediterranean

WHO Post OfficePO Box 7608Cairo 11371Egypt

Tel: +20 2 670 2535Fax: +20 2 670 2492

E-mail: [email protected]

WHO Regional Office for Europe

8, Scherfigsvej 2100 Copenhagen Ø Denmark

Tel: +45 39 17 17 17 Fax: +45 39 17 18 18

E-mail: [email protected]

48

For more information

World Health OrganizationAvenue Appia 20CH-1211 Geneva 27Switzerland

Tel: +41 22 791 21 11Fax: +41 22 791 41 60

E-mail: [email protected]: www.who.int/mental_health

Addresses of WHO

Regional Offices

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WHO Regional Office for South-East Asia

World Health HouseIndraprastha EstateMahatma Gandhi RoadNew Delhi 110 002India

Tel: +91 11 2337 0804Fax: +91 11 2337 0197

E-mail: [email protected]

WHO Regional Office for the Western Pacific

PO Box 29321000 ManilaPhilippines

Tel: +63 2 528 8001Fax: +63 2 521 1036

E-mail: [email protected] Evelyn Livia, 9 years old, Indonesia

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World Health Organization

Department of Mental Health and Substance Dependence

Avenue Appia 201211 Geneva 27Switzerland

Tel: +41 22 791 21 11Fax: +41 22 791 41 60

E-mail: [email protected]: www.who.int/mental_health

ISBN 92 4 156257 9