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High-precision measurement can be performed on various specimens.
Measurement of biventricular fibrosis of a crab-eating macaque
Hybrid Cell Count
Enables quick, high-accuracy quantification while eliminating variation in measurement results
Macro Cell Count 3D Imaging
Wide range of applications for enabling advanced analysis
From Z-stack images, a 3D image can be created with a single click.Spatial localization can be analyzed and determined accurately.
LINEUP GUIDEInverted All-in-One Fluorescence Microscope
Entry-level fluorescence microscope with motorized operation and high-sensitivity CCD
Basic System
Wide area navigation, high-resolution image stitching, Z-stack, and multi-point image capture
Multi-dimensional Observation/Capture System
Structured illumination captures high-contrast images equivalent to confocal microscopes
Optical Sectioning System
Long-term, live-cell imaging using incubation
Live-cell Incubation System
Accurate measurement is possible without the influence of variation and arbitrariness!
Output various conditions• Threshold setting• Correction values• Mask setting• Measuring range (Upper/lower limits)• Colocalization setting, etc.
All images are measured under the same conditions, which eliminates variations.
Condition file
Image provided by courtesy of: Naohide Ageyama, D.V.M., Ph.D., Tsukuba Primate Research Center, National Institute of Biomedical Innovation.Miyako Igarashi, assistant professor, Department of Cardiology, Faculty of Medicine, University of Tsukuba
• Area• Circumference• Longest diameter• Shortest diameter• Brightness (INT/MAX/MIN/AVE)• RGB brightness (INT/MAX/MIN/AVE)• Feret diameter (X/Y)• Count• Area ratio, etc.
Drag & drop
Drag with the left mouse button.Rotation
Mouse wheelZoom in/out
Drag with the right mouse button.Sectional view
Single click
Single click
Single click
Entry-level fluorescence microscope with advanced functions
Basic System
Achieves both high-speed screening and high-resolution capture
Multi-dimensional Observation/Capture System
Built-in darkroom
Standard equipped with a fully-motorized operation system
Large motorized stage supports observation of entire microtiter plates
Supports fluorescence, bright field, and phase-contrast images
High-sensitivity cooled monochrome/color CCD camera
Wide-field, ultra high-resolution images can be captured in full focus. Automatic capture function for extremely efficient screening
Enlarged view of a stage map
High sensitivity cooled monochrome camera
Low photobleach mode
Built-in darkroom
Reduces photobleaching during field-of-view adjustment
Fully automated system with a large motorized stagesupports the observation of entire microtiter plates
Space saving Flexible operation
High-speed auto focus
Quick focus adjustment with a single click
Flexible fluorescence observation wherever it’s needed
Footprint: 340 × 496 mm 13.39" × 19.53" Single unit supports fluorescence, bright field,and phase-contrast images
Image without fluorescence blurring achieved with a laser-free optical system
Optical Sectioning System
Capture everything including the observation area, target, and focus
Live-cell Incubation System
Chamber for CO2 concentration/temperature control included
Capture conditions can be set differently for each capture point.
Automatic focus adjustment depending on the change in the specimen
Anyone can capture clear images without mastering special techniques.
Optical sectioningMulti-dimensional observation/capture
Multi-dimensional observation/capture
Live cell imagingMulti-dimensional observation/capture
Basic Concept
Substantial basic performance
KEYENCE original functions
Capture points and conditions can be set as desired.No need for programming knowledge.
Due to photobleaching during observation at high resolution, part of the image is dark and the brightness is not distributed evenly.
Image with less photobleaching and uniform brightness
Normal observation mode Low photobleach mode
Conventional configuration plan
1.5 m 4.9' 0.34 m1.1'
Normal field of view
50000 × 50000 pixels
Specimen B: Fluorescence 2 CHSpecimen A: Phase-contrast + fluorescence
BZ-X Series
Extracts points with the best focus based on captured images
Optical sectioning system
Specimen
Lens
Fluorescence filter
High-sensitivity camera
Grid pattern
Light sourceCamellia leaf
Zebrafish bonemarrow
Capture condition reproduction function
The settings can be read from a captured image, including the lens used, filter, exposure time, position coordinates, image correction conditions, and so on, so the image can be reproduced.
Quick full focus
An image is automatically scanned in the Z direction with a single click to compose a fully-focused image.
HighHemoglobin
Absorption of light
WaterLow
In vivo window
1.00.90.80.70.60.50.40.30.20.1
0
Rel
ativ
e R
espo
nse
Wave Length (nm)
Alexa660mCherry
Texas Red
Alexa594
Nile Red
5-ALAAI Cy5
Cy5.5
Di-4 ANEPPSCy7
Alexa790ICG Near-infrared
400 500 600 700 900 1000800780
Wavelength sensitivity characteristic of BZ-X700
Light in this wavelength range is considered suitable for in vivo imaging because its absorption by substances such as hemoglobin and water is low and it has superior tissue permeation.
Wavelength sensitivity characteristic of KEYENCE conventional model
Stage view function allows positioning based on a map image representing various sample wells
Entry-level fluorescence microscope with advanced functions
Basic System
Achieves both high-speed screening and high-resolution capture
Multi-dimensional Observation/Capture System
Built-in darkroom
Standard equipped with a fully-motorized operation system
Large motorized stage supports observation of entire microtiter plates
Supports fluorescence, bright field, and phase-contrast images
High-sensitivity cooled monochrome/color CCD camera
Wide-field, ultra high-resolution images can be captured in full focus. Automatic capture function for extremely efficient screening
Enlarged view of a stage map
High sensitivity cooled monochrome camera
Low photobleach mode
Built-in darkroom
Reduces photobleaching during field-of-view adjustment
Fully automated system with a large motorized stagesupports the observation of entire microtiter plates
Space saving Flexible operation
High-speed auto focus
Quick focus adjustment with a single click
Flexible fluorescence observation wherever it’s needed
Footprint: 340 × 496 mm 13.39" × 19.53" Single unit supports fluorescence, bright field,and phase-contrast images
Image without fluorescence blurring achieved with a laser-free optical system
Optical Sectioning System
Capture everything including the observation area, target, and focus
Live-cell Incubation System
Chamber for CO2 concentration/temperature control included
Capture conditions can be set differently for each capture point.
Automatic focus adjustment depending on the change in the specimen
Anyone can capture clear images without mastering special techniques.
Optical sectioningMulti-dimensional observation/capture
Multi-dimensional observation/capture
Live cell imagingMulti-dimensional observation/capture
Basic Concept
Substantial basic performance
KEYENCE original functions
Capture points and conditions can be set as desired.No need for programming knowledge.
Due to photobleaching during observation at high resolution, part of the image is dark and the brightness is not distributed evenly.
Image with less photobleaching and uniform brightness
Normal observation mode Low photobleach mode
Conventional configuration plan
1.5 m 4.9' 0.34 m1.1'
Normal field of view
50000 × 50000 pixels
Specimen B: Fluorescence 2 CHSpecimen A: Phase-contrast + fluorescence
BZ-X Series
Extracts points with the best focus based on captured images
Optical sectioning system
Specimen
Lens
Fluorescence filter
High-sensitivity camera
Grid pattern
Light sourceCamellia leaf
Zebrafish bonemarrow
Capture condition reproduction function
The settings can be read from a captured image, including the lens used, filter, exposure time, position coordinates, image correction conditions, and so on, so the image can be reproduced.
Quick full focus
An image is automatically scanned in the Z direction with a single click to compose a fully-focused image.
HighHemoglobin
Absorption of light
WaterLow
In vivo window
1.00.90.80.70.60.50.40.30.20.1
0
Rel
ativ
e R
espo
nse
Wave Length (nm)
Alexa660mCherry
Texas Red
Alexa594
Nile Red
5-ALAAI Cy5
Cy5.5
Di-4 ANEPPSCy7
Alexa790ICG Near-infrared
400 500 600 700 900 1000800780
Wavelength sensitivity characteristic of BZ-X700
Light in this wavelength range is considered suitable for in vivo imaging because its absorption by substances such as hemoglobin and water is low and it has superior tissue permeation.
Wavelength sensitivity characteristic of KEYENCE conventional model
Stage view function allows positioning based on a map image representing various sample wells
High-precision measurement can be performed on various specimens.
Measurement of biventricular fibrosis of a crab-eating macaque
Hybrid Cell Count
Enables quick, high-accuracy quantification while eliminating variation in measurement results
Macro Cell Count 3D Imaging
Wide range of applications for enabling advanced analysis
From Z-stack images, a 3D image can be created with a single click.Spatial localization can be analyzed and determined accurately.
LINEUP GUIDEInverted All-in-One Fluorescence Microscope
Entry-level fluorescence microscope with motorized operation and high-sensitivity CCD
Basic System
Wide area navigation, high-resolution image stitching, Z-stack, and multi-point image capture
Multi-dimensional Observation/Capture System
Structured illumination captures high-contrast images equivalent to confocal microscopes
Optical Sectioning System
Long-term, live-cell imaging using incubation
Live-cell Incubation System
Accurate measurement is possible without the influence of variation and arbitrariness!
Output various conditions• Threshold setting• Correction values• Mask setting• Measuring range (Upper/lower limits)• Colocalization setting, etc.
All images are measured under the same conditions, which eliminates variations.
Condition file
Image provided by courtesy of: Naohide Ageyama, D.V.M., Ph.D., Tsukuba Primate Research Center, National Institute of Biomedical Innovation.Miyako Igarashi, assistant professor, Department of Cardiology, Faculty of Medicine, University of Tsukuba
• Area• Circumference• Longest diameter• Shortest diameter• Brightness (INT/MAX/MIN/AVE)• RGB brightness (INT/MAX/MIN/AVE)• Feret diameter (X/Y)• Count• Area ratio, etc.
Drag & drop
Drag with the left mouse button.Rotation
Mouse wheelZoom in/out
Drag with the right mouse button.Sectional view
Single click
Single click
Single click
KA11-1106
KEYENCE CORPORATION OF AMERICA669 River Drive, Suite 403, Elmwood Park, NJ 07407, U.S.A. PHONE: +1-888-539-3623 FAX: +1-855-539-0123
KEYENCE CANADA INC.E-mail: [email protected]
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T O C O N TA C T Y O U R L O C A L O F F I C E
Copyright (c) 2016 KEYENCE CORPORATION. All rights reserved. BZXLineupGuide-KA-TG-US 1106-1 611D52
The information in this publication is based on KEYENCE’s internal research/evaluation at the time of release and is subject to change without notice. Company and product names mentioned in this catalog are either trademarks or registered trademarks of their respective companies. The specifications are expressed in metric units. The English units have been converted from the original metric units.
KEYENCE MEXICO S.A. DE C.V.E-mail: [email protected]
CONTACT YOUR NEAREST OFFICE FOR RELEASE STATUS.GLOBAL NETWORK
Macro Cell Count
Conventional method
Image 1
Image 2
Image 3
Image ××
Image 1
Image 2 to ××
REDUCEDTIME
Observe
Quantify
Analysis
Data summarization
Auto measurement
& data
accumulation
Analysis
Observe
Quantify
Observe
Quantify
Observe
Quantify
Observe
Quantify
For more information, visit our website at:
www.keyence.com/bzx700
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