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CORRESPONDENCE Implementation of New Technology for CABG in Low- Risk Patients: Could It Be Too Soon? To the Editor: We read with interest and concern the case report from Dogan and colleagues [1]. Although we are well aware and supportive of the trend and of the principles towards a less invasive approach in coronary artery bypass graft (CABG) surgery, as well as the growing role of computer enhancement in enabling a totally endoscopic technique, several issues in this report are cause for concern. First, the exact place of hybrid revascularization (PTCA minimally invasive direct coronary artery bypass) in the arma- mentarium of myocardial revascularization remains blurry, es- pecially in young patients with no significant comorbidities, as reported here (patient 1), and this strategy should still be viewed with a healthy amount of skepticism. Secondly, the use of 7-0 polypropylene suture with the larger needle used for the anastomosis appear suboptimal for perfor- mance of internal thoracic artery to coronary anastomosis, especially for side-to-side anastomosis, as we believe that tech- nology should not modify the accepted surgical principles of microvascular anastomosis. Lastly and most importantly, the operative times and specifi- cally the ischemic times of 100 and 126 minutes (even with cardioplegic arrest) appear disproportionate compared with the classical approach of full sternotomy and cardioplegic arrest or beating heart surgery revascularization techniques currently available and carry, in our opinion, an unnecessarily high risk of ischemic injury to the myocardium. Another issue related to the Heartport system and the long cardiopulmonary bypass times is the moderate reperfusion injury to the cannulated leg of the 48-year-old patient that is part of the spectrum of vascular and groin complications which would be easily avoided by use of the more accepted approaches. Taken altogether, these issues make us question whether, even though “we have the technology,” we should submit patients with straightforward coronary insuffi- ciency to risks out of proportion to classical approaches. We fully agree with the closing statement of the authors that develop- ments in the computer system, instrumentation, and the Heart- port system are needed, and believe that such advances should be implemented, studied, and tested before ethically exposing patients with low surgical risks to complex procedures of ques- tionable benefits. The integrity of our profession is at stake as well as our capacity to safely and rationally implement new technology in the clinical arena. Are we the only ones thinking that way? Louis P. Perrault, MD, PhD Yves He ´bert, MD, FRCSC Michel Carrier, MD, FRCSC Research Center and Department of Surgery Montreal Heart Institute University of Montreal 5000 Belanger St East Montreal, Quebec H1T 1C8, Canada e-mail: [email protected]. Reference 1. Dogan S, Aybek T, Westphal K, Mierdl S, Moritz A, Wimmer- Greinecker G. Computer-enhanced totally endoscopic se- quential arterial coronary artery bypass. Ann Thorac Surg 2001;72:610 –1. 23 Reply To the Editor: We appreciate the poignant discussion of Dr Perrault and colleagues. Please allow us to express our point of view on these sensitive issues. We do not exactly understand the criticism regarding the indication of the procedure performed in patient 1. This had not been a planned hybrid revascularization. As we described pre- cisely in our report, a progression of the lesions in the left anterior descending and the diagonal branch were observed in recatheterization; this then led to the surgical procedure. At the date of the first intervention (percutaneous transluminal coro- nary angioplasty of the right coronary artery), the lesions in the left anterior descending and the diagonal branch were not considered advanced. At least in Europe it is not dogma to use 8-0 polypropylene suture for internal thoracic artery to coronary anastomosis. Many surgeons still use 7-0 sutures, which we definitely do not consider suboptimal. We agree that the ischemic times were long, though we do not really see a high risk of ischemic injury to healthy myocardium. Patients with impaired left ventricular function would not be appropriate candidates for such a procedure. We admit that the reperfusion injury of the cannulated leg is associated with the Port Access technique. This complication should be seen in relation to the fact that this has been the only reperfusion injury in our total series of 152 Port Access cases to date. We believe that this new technology has been implemented safely into our clinical practice in an ethically warrantable manner. To date, we have performed a variety of 62 totally endoscopic cardiac procedures with good results. Among those, five totally endoscopic sequential bypass grafting procedures were performed—the latest with an ischemic time of 46 minutes. Every innovation has its trade-offs at the beginning. If nobody takes on these challenges, progress in medicine will not take place. Selami Dogan, MD Gerhard Wimmer-Greinecker, MD, PhD Klinik fur Thorax- Herz- and Gefaßchirurgie Johann Wolfgang Goethe–Universitat Frankfurt Theodor Stern Kai 7 60590 Frankfurt, Germany e-mail: [email protected]. Triangular Resection of Prolapsing Anterior Mitral Leaflet To the Editor: In a recent issue of The Annals, Fasol and Joubert-Hu ¨ bner [1] reported a technique of a triangular resection of the anterior mitral leaflet (AML) to repair isolated segmental AML prolapse. This technique was initially introduced by Carpentier, but it was later abandoned because of a high incidence of recurrent regur- gitation [2]. However, in 1995, Colvin’s group [3] again empha- sized the usefulness and reliability of this technique for treat- ment of prolapsing AML. We employed this technique in 9 of 68 patients who under- went mitral valve repair for AML prolapse. During operation, © 2002 by The Society of Thoracic Surgeons Ann Thorac Surg 2002;73:1020 – 823 0003-4975/02/$22.00 Published by Elsevier Science Inc PII S0003-4975(01)03550-0

Implementation of new technology for CABG in low-risk patients: could it be too soon?

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CORRESPONDENCE

Implementation of New Technology for CABG in Low-Risk Patients: Could It Be Too Soon?To the Editor:

We read with interest and concern the case report from Doganand colleagues [1]. Although we are well aware and supportiveof the trend and of the principles towards a less invasiveapproach in coronary artery bypass graft (CABG) surgery, aswell as the growing role of computer enhancement in enablinga totally endoscopic technique, several issues in this report arecause for concern.

First, the exact place of hybrid revascularization (PTCA �minimally invasive direct coronary artery bypass) in the arma-mentarium of myocardial revascularization remains blurry, es-pecially in young patients with no significant comorbidities, asreported here (patient 1), and this strategy should still be viewedwith a healthy amount of skepticism.

Secondly, the use of 7-0 polypropylene suture with the largerneedle used for the anastomosis appear suboptimal for perfor-mance of internal thoracic artery to coronary anastomosis,especially for side-to-side anastomosis, as we believe that tech-nology should not modify the accepted surgical principles ofmicrovascular anastomosis.

Lastly and most importantly, the operative times and specifi-cally the ischemic times of 100 and 126 minutes (even withcardioplegic arrest) appear disproportionate compared with theclassical approach of full sternotomy and cardioplegic arrest orbeating heart surgery revascularization techniques currentlyavailable and carry, in our opinion, an unnecessarily high risk ofischemic injury to the myocardium. Another issue related to theHeartport system and the long cardiopulmonary bypass times isthe moderate reperfusion injury to the cannulated leg of the48-year-old patient that is part of the spectrum of vascular andgroin complications which would be easily avoided by use of themore accepted approaches. Taken altogether, these issues makeus question whether, even though “we have the technology,” weshould submit patients with straightforward coronary insuffi-ciency to risks out of proportion to classical approaches. We fullyagree with the closing statement of the authors that develop-ments in the computer system, instrumentation, and the Heart-port system are needed, and believe that such advances shouldbe implemented, studied, and tested before ethically exposingpatients with low surgical risks to complex procedures of ques-tionable benefits. The integrity of our profession is at stake aswell as our capacity to safely and rationally implement newtechnology in the clinical arena. Are we the only ones thinkingthat way?

Louis P. Perrault, MD, PhDYves Hebert, MD, FRCSCMichel Carrier, MD, FRCSC

Research Center and Department of SurgeryMontreal Heart InstituteUniversity of Montreal5000 Belanger St EastMontreal, Quebec H1T 1C8, Canadae-mail: [email protected].

Reference

1. Dogan S, Aybek T, Westphal K, Mierdl S, Moritz A, Wimmer-Greinecker G. Computer-enhanced totally endoscopic se-quential arterial coronary artery bypass. Ann Thorac Surg2001;72:610–1. 23

ReplyTo the Editor:

We appreciate the poignant discussion of Dr Perrault andcolleagues. Please allow us to express our point of view on thesesensitive issues.

We do not exactly understand the criticism regarding theindication of the procedure performed in patient 1. This had notbeen a planned hybrid revascularization. As we described pre-cisely in our report, a progression of the lesions in the leftanterior descending and the diagonal branch were observed inrecatheterization; this then led to the surgical procedure. At thedate of the first intervention (percutaneous transluminal coro-nary angioplasty of the right coronary artery), the lesions in theleft anterior descending and the diagonal branch were notconsidered advanced.

At least in Europe it is not dogma to use 8-0 polypropylenesuture for internal thoracic artery to coronary anastomosis.Many surgeons still use 7-0 sutures, which we definitely do notconsider suboptimal.

We agree that the ischemic times were long, though we do notreally see a high risk of ischemic injury to healthy myocardium.Patients with impaired left ventricular function would not beappropriate candidates for such a procedure.

We admit that the reperfusion injury of the cannulated leg isassociated with the Port Access technique. This complicationshould be seen in relation to the fact that this has been the onlyreperfusion injury in our total series of 152 Port Access cases todate.

We believe that this new technology has been implementedsafely into our clinical practice in an ethically warrantablemanner. To date, we have performed a variety of 62 totallyendoscopic cardiac procedures with good results. Among those,five totally endoscopic sequential bypass grafting procedureswere performed—the latest with an ischemic time of 46 minutes.Every innovation has its trade-offs at the beginning. If nobodytakes on these challenges, progress in medicine will not takeplace.

Selami Dogan, MDGerhard Wimmer-Greinecker, MD, PhD

Klinik fur Thorax- Herz- and GefaßchirurgieJohann Wolfgang Goethe–Universitat FrankfurtTheodor Stern Kai 760590 Frankfurt, Germanye-mail: [email protected].

Triangular Resection of Prolapsing Anterior MitralLeafletTo the Editor:

In a recent issue of The Annals, Fasol and Joubert-Hubner [1]reported a technique of a triangular resection of the anteriormitral leaflet (AML) to repair isolated segmental AML prolapse.This technique was initially introduced by Carpentier, but it waslater abandoned because of a high incidence of recurrent regur-gitation [2]. However, in 1995, Colvin’s group [3] again empha-sized the usefulness and reliability of this technique for treat-ment of prolapsing AML.

We employed this technique in 9 of 68 patients who under-went mitral valve repair for AML prolapse. During operation,

© 2002 by The Society of Thoracic Surgeons Ann Thorac Surg 2002;73:1020–823 • 0003-4975/02/$22.00Published by Elsevier Science Inc PII S0003-4975(01)03550-0