COMMUNITY COLLEGE OF ALLEGHNEY COUNTYALLEGHENY CAMPUS

DEPARTMENT OF NURSING

NRN101 AND NRN102 DRUG CARD

Drug Trade Name:humalog

Generic Name:Insulin lispro

Classification:Antidiabeticinsulin analogs

Usual Ranges:Adult: Pediatric: >3yrInitial 0.5-0.8 u/kg/day subqHoneymoon phase0.2-0.5 u/kg/day subqSplit dose therapy0.5-1.2 u/kg/day subqAdolescent growth spurts0.8-1.5 u/kg/day subqInsulin resistance 0.7-2.5 u/kg/day subqRecommended Frequency of Administration:2-5 times daily before meals subqRecommended Route of Administration:SubqSC infusion via pump

Physiological Action:(How drug works in the body)Regulates glucose metabolism; lowers blood glucose by stimulating peripheral glucose uptake by skeletal muscle & fat, and by inhibitating hepatic glucose production.

Uses:Treat diabetes mellitus (DM) by helping sugar get into cells.

Sliding scale: 4 units with meal adjust by 2 units every 3 days until BG is in range.

100units/mL (10mL vial)100 units/mL (3mL pen or cartridge)

Common Side Effects:

Injection site reactions. Pain, redness, irritation. Hypoglycemia

Adverse Side Effects:Rash, itching, swelling specifically facial, tachycardia, severe dizziness, sweating, trouble breathing, hypokalemia

Contraindications with food or other drugs:AlcoholAntidiabetic drugs, certain antipsychotics, certain blood pressure meds (prils), MAOI’s, thyroid hormones.

Pregnancy Category:

C *some texts do say BIt is safe with breast feeding.

NURSING CONSIDERATIONS (Before, during or after administration):Fast acting. When used as meal-time insulin use 15mins before or after meal. Inject to upper arm, abdomen, thigh, or buttocks. Rotate location site to avoid lipodystrophy.Avoid alcoholCheck blood sugars regularly Do not use diluted or mixed with pumps. Infusion sites should be rotated.

RATIONALE for this PATIENT:(Why prescribed for patient)

PRESCRIBEDDosage Route Frequency

TIMES GIVEN:

RT Reviewed June 1985/LAB Reviewed June 1989/LAB Reviewed June 1990/KAC Revised July 1991/HPO Revised May 2002/LAC Revised January 2003