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www.digitalpathology2016.org | 1
13th EUROPEAN CONGRESS
ON DIGITAL PATHOLOGY
– HOSTED BY THE GERMAN SOCIETY OF PATHOLOGY –
www.digitalpathology2016.org
MAY 25th–28th, 2016LANGENBECK-VIRCHOW-HAUS
BERLIN, GERMANY
FINAL
PROGRAM
#ecdp2016
www.digitalpathology2016.org | 3
Sharing multiplies yourknowledgeLeveraging decades of Philips experience in
clinical digital transformation, the IntelliSite
pathology solution can provide you the
speed, quality and scalability you need.
High resolution images, collaboration
features and case management support
tools can help you make that next step in
workfl ow improvement and accelerate
knowledge sharing between care providers.
Visit us at the Philips booth #3 orwww.philips.com/digitalpathology
IntelliSite Pathology Solutions
Welcome Message 4
Contacts/Committee 5
Acknowledgements 7
DETAILED PROGRAM
Wednesday, May 25, 2016 8
Thursday, May 26, 2016 10
Friday, May 27, 2016 21
Saturday, May 28, 2016 29
EPOSTER SESSIONS
Thursday, May 26, 2016 34
INDUSTRIAL EXHIBITION
List of Sponsors and Exhibitors 38
Floor Plan 39
Congress Information 41
Index of Presenting Authors 44
TABLE OF CONTENTS
TABL
E O
F CO
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NTS
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CONGRESS PRESIDENT
Prof. Dr. Peter HufnaglHead, Digital Pathology & ITInstitute of Pathology, “Rudolf-Virchow-House”Charité – Universitätsmedizin Berlin10117 Berlin, Germany
HONORARY PRESIDENT
Prof. Dr. Dr. Klaus KayserUICC-TPCCCharité – Universitätsmedizin Berlin10117 Berlin, Germany
WITH THE CONTRIBUTION OF
European Society of PathologyGerman Society of Pathology e. V.Bundesverband Deutscher Pathologen e. V.
SCIENTIFIC ADVISORY BOARD
Marcial Garcia Rojo, SpainFrederick Klauschen, Germany
LOCAL ORGANIZING COMMITTEE
Norman Zerbe, GermanyThomas Schrader, GermanyPlamen Simeonov, GermanyIris Klempert, GermanyWerner Stenzel, GermanyGunter Haroske, GermanyGian Kayser, GermanyPeter Hufnagl, GermanyManfred Dietel, Germany
SCIENTIFIC COMMITTEE
David Ameisen, FranceBruce A. Beckwith, United StatesPhilippe Belhomme, FrancePhilippe Bertheau, FranceArrigo Bondi, ItalyPeter Boor, GermanyThomas Boudier, FranceLori Bridal, FranceGloria Bueno, SpainPhilippe Camparo, FranceFrédéric Charlotte, FranceClaudio Clemente, ItalyChristel Daniel, FranceVincenzo Della Mea, ItalyNicky D’Haene, BelgiumNicolas Elie, FranceFriedrich Feuerhake, GermanyNiels Grabe, GermanyCatherine Guettier, FranceChristoph Harms, GermanyOlaf Hellwich, GermanyGunter Haroske, GermanyFrank Heppner, GermanyChao-Hui Huang, SingaporePeter Hufnagl, GermanyAndré Huisman, NetherlandsMichael Hummel, GermanyJorma Isola, FinlandGian Kayser, GermanyKlaus Kayser, GermanyApril Khademi, CanadaJacques Klossa, FranceGabriel Landini, United KingdomArvydas Laurinavicius, LithuaniaMarylène Lejeune, FrancePeter Leškovský, SpainRichard Levenson, United StatesOlivier Lezoray, FranceNicolas Lomenie, FranceShijian Lu, Singapore
CONTAC TS/COMMIT TEE
CON
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TS/C
OM
MIT
TEE
The 13th European Congress on Digital Pathology (ECDP 2016) will be held in Berlin, Germany, from May, 25–28, 2016. Digital pathology, originally an off shoot of telepathology is advancing to incorporate modern medicine with systems science, image processing, business process modelling and knowledge management. Methodological changes in microscopic techniques, imaging, molecular pathology, genetics and bioinformatics are drivers of digital pathology.
The congress program is drawing a bow from imaging technology and image analysis to workfl ow integration and computer aided diagnosis. Several roundtables are focused on actual developments like clinical workfl ow integration, integrative pathology and translational medicine. Pecha kucha, science slam and ePoster sessions off er modern formats of communication.
Participants have online access to all relevant information including schedule, presentations, abstracts as well as guidance through the industrial exhibition using the congress App.
With respect to rate of technical developments during the past years, time is right for an overview of potentials of scanning technology and their applicability in daily practice. The industrial exhibition shows the continuing growth and advances in the fi eld and refl ects the broad usability of the technology.
WELCOME MESSAGE
WEL
COM
E M
ESSA
GE
Prof. Dr. Peter Hufnagl Prof. Dr. Dr. Klaus Kayser
Congress President Honorary President
6 | www.digitalpathology2016.org www.digitalpathology2016.org | 7
ACKNOWLEDGEMENTS
The organizers of the ECDP Congress 2016 gratefully acknowledge the support of the following sponsors and exhibitors:
GOLD PARTNERS
SILVER PARTNERS
SPONSORS & EXHIBITORS
ACK
NO
WLE
DG
EMEN
TS
CONTAC TS/COMMIT TEE
Mikael Lundin, FinlandAnant Madabhushi, United StatesKonradin Metze, BrasilHenning Müller, GermanySarah Nußbeck, GermanyLiron Pantanowitz, United StatesBenoît Plancoulaine, FranceVytenis Punys, LithuaniaDaniel Racoceanu, FranceNasir Rajpoot, United KingdomLudovic Roux, FranceIsabelle Salmon, BelgiumThomas Schrader, GermanyNicolas Signolle, FranceJanina Słodkowska, PolandJanusz Szymas, PolandCornelia Tennstedt-Schenck, GermanyBernard Têtu, FranceDarren Treanor, United KingdomKatarzyna Zarychta, GermanyNorman Zerbe, Germany
PROFESSIONAL CONGRESS ORGANIZER
MCI Deutschland GmbHMCI | Berlin Offi ceMarkgrafenstrasse 5610117 Berlin, GermanyPhone: +49 30 204590Fax: +49 30 2045950
On-site Phone:
+49 160 93907368
VENUES
Langenbeck-Virchow Haus GbR Luisenstrasse 58/5910117 Berlin, Germany
Institut für Pathologie, Charité – Universitätsmedizin BerlinCampus MitteCharitéplatz 110117 Berlin, Germany
CON
TAC
TS/C
OM
MIT
TEE
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SCIENTIFIC PROGRAM WEDNESDAY, MAY 25, 2016 SCIENTIFIC PROGRAM WEDNESDAY, MAY 25, 2016
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THU THU
FRI FRI
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OTHER MEETINGS AND WORKSHOPS
9:00 AM–5:00 PMRoom:
Emil von Behring
Cognition Master: Workshop
OTHER MEETINGS AND WORKSHOPS
11:30 AM–12:30 PMRoom: Lounge
AIDPATH Meeting
OTHER WORKSHOP
1:00 PM–3:00 PMRoom: Lounge
AIDPATH Workshop
SP01 SPECIAL SESSION
5:30 PM–7:00 PMRoom: Hörsaal
Opening Ceremony
Chairs: P. Hufnagl, Congress President (Berlin, Germany)K. Kayser, Honorary President (Heidelberg, Germany)
SP01.01 Welcome by the German Society of Pathology J. Maas* (Germany)Secretary General German Society of Pathology (DGP), Berlin, Germany
SP01.02 Welcome to Charité Berlin:Rudolf Virchow and Berlin’s tradition in pathology M. Dietel* (Germany)Director Institute of Pathology (Rudolf-Virchow-Haus) Charité, Berlin, Germany
SP01.03 Opening lecture:The 13th ECDP – a scientifi c overview P. Hufnagl* (Germany)Berlin, Germany
SP01.04 Introductory presentation:ECDP 2016 organization and techniques N. Zerbe* (Germany)Berlin, Germany
SP01.05 Ceremonial address: History of the European conference series on digital pathology: memories and perspectives K. Kayser* (Germany)Heidelberg, Germany
SOCIAL PROGRAM
7:00 PM–9:30 PM Get Together in the Exhibition Area
1ST FLOOR
Hörsaal
4TH FLOOR
E. v. Behring
GROUND FLOOR
Lounge
2ND FLOOR
R. Virchow
5TH FLOOR
A. Bier
9:00 AM OTHER IHE/DICOM IHE/DICOM 9:00 AM
Cognition Master:
Workshop
IHE WG PaLM
Meeting
DICOM WG 26
Meeting
10:00 AM 10:00 AM
11:00 AM 11:00 AM
OTHER
AIDPATH Meeting12:00 PM 12:00 PM
1:00 PM OTHER 1:00 PM
AIDPATH Workshop
2:00 PM 2:00 PM
3:00 PM IHE/DICOM 3:00 PM
IHE WG PaLM &
DICOM WG 26 Joint
Meeting
4:00 PM 4:00 PM
5:00 PM 5:00 PM
SP01
Opening Ceremony
6:00 PM 6:00 PM
7:00 PM SOCIAL PROGRAM 7:00 PM
Get Together in the Exhibition Area
Scientfi c Session
Keynote Lecture
Panel Discussion
ePoster Session
IHE/DICOM
Lunch Symposium
Social Program
Special Session
Other Meetings and Workshops
10 | www.digitalpathology2016.org www.digitalpathology2016.org | 11
SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016 SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016
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KN01 KEYNOTE LECTURE
9:00 AM–10:00 AMRoom: Hörsaal
Keynote I
Chair: G. Kayser (Freiburg, Germany)
KN01.01 Computer assisted medical imaging: from research to clinical application H. K. Hahn* (Bremen, Germany)Fraunhofer MEVIS, Bremen, Germany
10:00 AM–10:30 AM COFFEE BREAK
SY01 SYMPOSIUM
10:30 AM–12:00 PMRoom: Hörsaal
Image Analysis I – Quantifi cation
Chairs: A. Laurinavicius (Vilnius, Lithuania)M. Vyberg (Aalborg, Denmark)
10:30 AM–10:45 AM SY01.01 Impact of tissue sampling on accuracy of Ki67 immunohistochemistry evaluation in breast cancer J. Besusparis*1,2 (Lithuania), B. Plancoulaine³, A. Rasmusson¹, R. Augulis1,2, A. R. Green4, I. O Ellis4,5, A. Laurinaviciene1,2, P. Herlin², A. Laurinavicius1,2
¹National Center of Pathology, affi liate of Vilnius University Hospital Santariskiu
Clinics, Vilnius, Lithuania, ²Vilnius University, Faculty of Medicine, Vilnius,
Lithuania, ³University of Normandy Caen, Path-Image/BioTiCla, Caen, France, 4University of Nottingham, Division of Cancer and Stem Cells, School of Medicine,
Nottingham, United Kingdom, 5Nottingham City Hospital University of Nottingham,
Histopathology, Nottingham, United Kingdom
10:45 AM–11:00 AM SY01.02 Morphometric analysis in benign, atypical and invasive breast lesions and its correlation with histological diagnosis, tumour grading and HER 2 overexpression R. Gahlaut*¹ (United Kingdom), B. Arora²¹Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trusts,
Histopathology, Cambridge, United Kingdom, ²Postgraduate Institute of Medical
sciences, Histopathology, Rohtak, India
11:00 AM–11:15 AM SY01.03 Signifi cance of morphometric analysis of HPV-induced cervical dysplasia B. Vukomanovic Djurdjevic*(Serbia)Military Medical Academy, Pathology, Belgrade, Serbia
11:15 AM–11:30 AM SY01.04 Analysis of color standardization methods for the automatic quantifi cation of IHQ stain in breast TMAM. M. Fernandez-Carrobles, O. Deniz, G. Bueno* (Spain)Universidad de Castilla-La Mancha, VISILAB, Ciudad Real, Spain
1ST FLOOR
Hörsaal
5TH FLOOR
R. Koch
2ND FLOOR
R. Virchow
GROUND FLOOR
Lounge
9:00 AM KN01 9:00 AM
Computer Assisted
Medical Imaging: from
Research to Clinical
Application
10:00 AMCoff ee Break
10:00 AM
SY01 SY02 SY03
Image Analysis I –
Quantifi cationTelepathology
Data Integration
and Modelling
11:00 AM 11:00 AM
12:00 PM 12:00 PM
LS01
Lunch Break
3DHistech – Scientifi c and
Practical Aspects in Digital
Pathology
Lunch Break
1:00 PM 1:00 PM
SY04 SY05 PS01
Virtual Microscopy Computer Aided Diagnosis ePoster Session I
2:00 PM 2:00 PM
3:00 PMCoff ee Break
3:00 PM
SY06 SY07 PS02
Diagnostic Advances Imaging Technology ePoster Session II
4:00 PM 4:00 PM
5:00 PMCoff ee Break
5:00 PM
PD01
Imaging in Clinics and
Research6:00 PM 6:00 PM
OTHER
ECDP Council Meeting7:00 PM 7:00 PM
SOCIAL PROGRAM
Guided tour through Charité
Scientfi c Session
Keynote Lecture
Panel Discussion
ePoster Session
IHE/DICOM
Lunch Symposium
Social Program
Special Session
Other Meetings and Workshops
12 | www.digitalpathology2016.org www.digitalpathology2016.org | 13
SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016 SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016
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11:15 AM–11:30 AM SY02.04 Towards effi cient collaborative digital pathology: a pioneer initiative of the FlexMIm projectD. Racoceanu¹, D. Ameisen², A. Veillard³,B. Ben Cheikh¹, E. Attieh4, P. Brezillon5, J.-B. Yunès6,J.-M. Temerson7, L. Toubiana8, V. Verger9, J.-F. Pomerol9,J. Klossa9, F. Lallemand10, P. Constant10, F. Capron11,C. Guettier12, N. Phan13, P. Bertheau*14 (France)¹Sorbonne Universités, UPMC Univ Paris 06, CNRS, INSERM, Laboratoire dImagerie
Biomédicale (LIB), Paris, France, ²University Paris Diderot, Paris, France,
³Sorbonne Universités, UPMC Univ Paris 06, CNRS, Image & Pervasive Access
Lab (IPAL), Singapore, Singapore, 4UPMC Univ Paris 06, Paris, France, 5Sorbonne
Universités, UPMC Univ Paris 06, CNRS, Laboratoire dInformatique de Paris 6 (LIP6),
Paris, France, LIP6, Paris, France,6University Paris Diderot, LIAFA, Paris, France, 7Orange Labs, Orange Group, Grenoble, France, 8Orange Group, Paris, France, 9Tribvn, Chatillon, France, 10Pertimm, Asnières, France, 11UPMC Univ Paris 06/Hosp
Pitié-Salpétrière-APHP, Service de Pathologie, Paris, France, 12University Paris Sud/
Hosp Kremlin-Bicetre-APHP, Le Kremlin Bicêtre, France, 13Hosp St-Louis-APHP,
Paris, France,14University Paris Diderot/Hosp St-Louis APHP/INSERM UMR-S-1165,
Paris, France
11:30 AM–11:45 AM SY02.05 An innovative telepathology solution for developing countries M. Botteghi*¹ (Italy), N. Masalu², V. Stracca³, D. Amadori4
¹Università Politecnica delle Marche, Department of Clinical and Molecular Sciences,
Ancona, Italy, ²Bugando Medical Centre, Oncology department, Mwanza, Tanzania,
United Republic of, ³Associazione Patologi oltre Frontiera NGO, Milano, Italy, 4Istituto
Scientifi co Romagnolo per lo Studio e la Cura dei Tumori IRST, Meldola, Italy
11:45 AM–12:00 PM SY02.06 Muscinous neoplasms of the appendix and peritoneum: virtual microscopy for histomorphologic assessment and intraobserver diagnostic reproducibility I. Villa*¹ (France), L. Villeneuve², N. J. Carr³, S. Isaac², O. Glehen², M. Capovilla², A. Chevallier², S. Croce², R. Kaci², G. Langaverous², M.-H. Laverriere², A. Leroux-broussier², E. Mery², F. Poizat², S. Valmary-Degano², V. Verriele-Beurrier², F.-N. Gilly², F. Bibeau², P. Dartigues1,2
¹Gustave Roussy, Biologie et Pathologie Médicales, Villejuif, France, ²RENAPE/RENA-
PATH Group, Centre Hospitalier Lyon Sud, Lyon, France, ³Basingstoke and North
Hampshire Hospital, Peritoneal Malignancy Centre, Southampton, United Kingdom
11:30 AM–11:45 AM SY01.05 Validation of virtual double staining for estimation of Ki67 proliferation indices in breast carcinomas R. Røge* (Denmark), R. Riber-Hansen, S. Nielsen, M. VybergAalborg University Hospital, Institute of Pathology, Aalborg, Denmark
11:45 AM–12:00 PM SY01.06 Digital image analysis of HER2 immunostained gastric and gastroesophageal junction adenocarcinomas S. L. Nielsen* (Denmark), S. Nielsen, M. VybergAalborg University Hospital, Institute of Pathology, Aalborg, Denmark
SY02 SYMPOSIUM
10:30 AM–12:00 PMRoom: Robert Koch
Telepathology
Chairs: D. Racoceanu (Paris, France)C. Zhou (Vancouver, Canada)
10:30 AM–10:45 AM SY02.01 Bridge the distance between breast pathologists: when the SENOPATH network opens up to the telepathology C. Franchet*¹ (France), M.-L. Quintyn-Ranty¹, P. Caveriviere², K. Gordien³, F.-X. Frenois¹, V. Maisongrosse¹, E. Mery¹, P. Wuithier4, J. Reyre², V. Laborie5, V. Rolland6, I. Thibaut7, M. Jamme-Lallemand8, J. Palasse9, B. Despax6, P. Brousset¹, M. Lacroix-Triki10, R. Duprez-Paumier¹¹University Cancer Institute – Oncopole, Pathology, Toulouse, France, ²Feuillants
Laboratory, Toulouse, France, ³ONCOMIP, Toulouse, France, 4Pathology Laboratory,
Tarbes, France, 5Pathology Laboratory, Montauban, France, 6Récollets Street
Pathology Laboratory, Toulouse, France, 7Les Coteaux Pathology Laboratory,
Toulouse, France, 8Claude Bernard Clinic, Pathology, Albi, France, 9Viscose Street
Pathology Laboratory, Toulouse, France, 10Gustave Roussy Institute, Villejuif, France
10:45 AM–11:00 AM SY02.02 Comparison of digital and conventional measurements of the morphometric prognostic parameters in cutaneous melanoma V. T. Moldovan*¹ (Romania), L. Ali¹, M. Costache², M. Sajin², A. Lazaroiu²¹Victor Babes National Institute of Pathology, Pathology, Bucuresti, Romania,
²Bucharest Emergency University Hospital, Surgical Pathhology, Bucuresti, Romania
11:00 AM–11:15 AM SY02.03 Provincial telepathology networks and their connection into national/central telepathology network in China: a result analysis from 2012 to 2015 C. Zhou*¹ (Canada), Y. Jiao², Z. Zhang³, J. Chen4
¹British Columbia Cancer Agency/University of British Columbia, Department of
Pathology, Vancouver, Canada, ²Commission of Health and Family Planning, Quality
Control, Beijing, China, ³Commission of Health and Family Planning, Beijing, China, 4Beijing Union Hospital, Department of Pathology, Chinese Pathology Quality Control
Program, Beijing, China
14 | www.digitalpathology2016.org www.digitalpathology2016.org | 15
SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016 SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016
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LS01 LUNCH SYMPOSIUM
12:15 PM–1:15 PMRoom: Robert Koch
3DHistech: Scientifi c and Practical Aspects
in Digital Pathology
Chair: T. Regényi (Budapest, Hungary)
12:15 PM–12:35 PM LS01.01 Digital pathology for and in the routine: new generation systems B. Molnár* (Hungary)Budapest, Hungary
12:35 PM–12:55 PM LS01.02 Third generation’s scanning technologies V. Varga* (Hungary)Budapest, Hungary
12:55 PM–1:15 PM LS01.03 High level digital microscopy: from image optimization to whole tissue analysis G. Kiszler* (Hungary)Budapest, Hungary
SY04 SYMPOSIUM
1:30 PM–3:00 PMRoom: Hörsaal
Virtual Microscopy
Chairs: P. Hufnagl (Berlin, Germany)D. Pilutti (Udine, Italy)
1:30 PM–1:45 PM SY04.01 Block-centric visualization of histological whole slide images with application to revealing growth-patterns of early colorectal adenomas and aberrant crypt foci N. Zerbe*1,2,3 (Germany), D. Heim¹, J. Kantonen4, F. Klauschen¹, K. Schlüns¹, P. Hufnagl1,2,3, H. Bläker¹¹Charité – Universitätsmedizin Berlin, Institute of Pathology, Berlin, Germany,
²Charité – Universitätsmedizin Berlin, Centralized Biomaterialbank (ZeBanC), Berlin,
Germany, ³University of Applied Sciences – HTW Berlin, Dept. Applied Informatics,
Berlin, Germany, 4Haartman Institute, Dept. of Pathology, University of Helsinki,
Helsinki, Finland
SY03 SYMPOSIUM
10:30 AM–12:00 PMRoom: Rudolf Virchow
Data Integration and Modelling
Chairs: C. Seebode (Berlin, Germany)P. Siregar (Chantepie, France)
10:30 AM–10:45 AM SY03.01 Next generation biobanking – from biorepository to data integration center C. Stephan*¹ (Germany), M. Zünkeler¹, D. Bieling², K. Säger³, S. Lohmann4, N. Zerbe4, P. Hufnagl4
¹Kairos GmbH, Bochum, Germany, ²Kairos GmbH, Berlin, Germany,
³VMscope GmbH, Berlin, Germany, 4Charité – Universitätsmedizin Berlin,
Institute of Pathology, Berlin, Germany
10:45 AM–11:00 AM SY03.02 Biobank semantic information management with the health intelligence platform C. Seebode*¹ (Germany), M. Ort¹, S. González Álvarez¹, C. R. A. Regenbrecht²¹ORTEC medical GmbH, Berlin, Germany, ²Institute for Pathology Charité –
Universitätsmedizin Berlin, Berlin, Germany
11:00 AM–11:15 AM SY03.03 Data architecture for a clincal data repository – evaluation and design at Charité – Universitätsmedizin Berlin M. Mallach* (Germany), M. PeukerCharité – Universitätsmedizin Berlin, IT Department, Berlin, Germany
11:15 AM–11:30 AM SY03.04 Cross-fertilization between computational morphogenesis and digital pathology P. Siregar* (France), N. JulenIntegrative Biocomputing, Chantepie, France
12:15 PM–1:15 PM LUNCH BREAK
16 | www.digitalpathology2016.org www.digitalpathology2016.org | 17
SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016 SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016
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1:45 PM–2:00 PM SY05.02 Sustainable formal representation of breast cancer grading histopathological knowledge L. Traore*1,2,3 (France), C. Daniel2,4, M.-C. Jaulent², T. Schrader5, D. Racoceanu³, Y. Kergosien2,6
¹Université Pierre Marie Curie, UPMC-Paris 6, LIMICS: INSERM U 1142, LIB: CNRS
UMR 7371, INSERM U 1146, Paris, France, ²Sorbonne Universités, UPMC Univ Paris
06, INSERM, Université Paris 13, Sorbonne Paris Cité, Laboratoire dInformatique
Médicale et Ingénierie des Connaissances en eSanté (LIMICS – UMR_S 1142),
15 rue de lécole de médecine, Paris, France, ³Sorbonne Universités, UPMC Univ
Paris 06, CNRS, INSERM, Laboratoire dImagerie Biomédicale (LIB), 75013, Paris,
France, 4Assistance Publique-Hôpitaux de Paris (AP-HP), CCS SI Patient, Paris, France, 5University of Applied Sciences Brandenburg Magdeburger, Department Informatics
and Media, Brandenburg, Germany, 6Département dInformatique Université de
Cergy-Pontoise, Cergy-Pontoise, France
2:00 PM–2:15 PM SY05.03 Automated Image Analysis of HER2 FISH enables new defi nitions of genetic heterogeneity in breast cancer tissueG. Radziuviene1,2, A. Rasmusson², R. Augulis2,3,D. Lesciute-Krilaviciene1,2, A. Laurinaviciene2,3, E. Clim4, A. Laurinavicius*2,3 (Lithuania)¹Vilnius University, Faculty of Natural Sciences, Vilnius, Lithuania,
²National Center of Pathology, affi liate of Vilnius University Hospital Santariskiu
Clinics, Vilnius, Lithuania, ³Vilnius University, Faculty of Medicine, Vilnius, Lithuania, 4TissueGnostics, Iasi, Romania
2:15 PM–2:30 PM SY05.04 Long-term application of automated Ki67 quantifi cation in routine breast cancer diagnostics S. Wienert*¹ (Germany), F. Klauschen¹, S. Loibl², G. von Minckwitz², C. Denkert¹¹Charité – Universitätsmedizin Berlin, Institut für Pathologie, Berlin, Germany,
²GBG Forschungs GmbH, Neu-Isenburg, Germany
2:30 PM–2:45 PM SY05.05 Computer-assisted infl ammation analysis of kidney-graft biopsy to improve risk stratifi cation in allograft rejection V. Meas-Yedid*1,2 (France), A. Sicard³, M. Rabeyrin4, A. Koenig³, S. Ducreux5, F. Dijoud6, L. Badet7, E. Morelon³, J.-C. Olivo-Marin1,2, O. Thaunat³¹Institut Pasteur, Cell Biology and Infection, Paris, France, ²CNRS, UMR 3691,
Paris, France, ³Edouard Herriot Hospital, Nephrology, Transplantation and Clinical
Immunology Department, Lyon, France, 4Hospices Civils de Lyon, Pathology
Department, Lyon, France, 5Etablissement Français du Sang, Histocompatibility,
Lyon, France, 6Groupement Hospitalier Lyon EST, Pathology Department, Lyon,
France, 7Edouard Herriot Hospital, Urology and transplantation department,
Lyon, France
1:45 PM–2:00 PM SY04.02 Input device research for digital pathology. An ergonomic outlook E. Alcaraz-Mateos*1,2 (Spain), F. Caballero-Aleman³, M. Albarracin4, F. Carceles4, R. Hernandez4, S. Hernandez-Kakauridze4, L. Hernandez4, I. Jimenez4, A. Lopez4, C. Moreno4, M. Perez-Ramos², A. Nieto-Olivares², N. Sanchez-Campoy5, I. Martinez-Gonzalez-Moro6, E. Poblet-Martinez7
¹Hospital Universitario Morales Meseguer, Pathology, Murcia, Spain,
²Morales Meseguer University Hospital, Pathology, Murcia, Spain, ³Morales Meseguer
University Hospital, Intensive Care Unit, Murcia, Spain, 4University of Murcia,
Faculty of Medicine, Murcia, Spain, 5National Institute of Statistics, Lerida, Spain, 6University of Murcia, Faculty of Physiotherapy, Murcia, Spain, 7Reina Sofi a University
Hospital, Pathology, Murcia, Spain
2:00 PM–2:15 PM SY04.03 Portable viewers for whole slide images L. Alfaro* (Spain)Hospital Virgen del Consuelo, Pathology, Valencia, Spain
2:15 PM–2:30 PM SY04.04 Cytomine: an open-source software for collaborative analysis of whole-slide images R. Marée*¹ (Belgium), L. Rollus¹, B. Stévens¹, R. Hoyoux1, G. Louppe¹, R. Vandaele¹, J.-M. Begon¹, P. Kainz², P. Geurts¹, L. Wehenkel¹¹University of Liège, Systems and Modeling, Liege, Belgium, ²Medical University
Graz, Institute of Biophysics, Graz, Austria
2:30 PM–2:45 PM SY04.05 A globally optimum parallelizable whole slide image registration algorithm A. Çapar*¹ (Turkey), T. Çöplü², I. C. Türkmen³¹Informatics Institute/Istanbul Technical University, Istanbul, Turkey, ²Argenit Ltd.,
Istanbul, Turkey, ³Istanbul Medipol University, Pathology, Istanbul, Turkey
SY05 SYMPOSIUM
1:30 PM–3:00 PMRoom: Robert Koch
Computer Aided Diagnosis
Chairs: K. Kayser (Heidelberg, Germany)H. K. Hahn (Bremen, Germany)
1:30 PM–1:45 PM SY05.01 Structure, function, and predictive diagnosis algorithms K. Kayser*¹ (Germany), S. Borkenfeld², R. Carvalho³, G. Kayser4
¹Charité, Pathology, Berlin, Germany, ²IAT, Heidelberg, Germany, ³General Hospital,
Pathology, Lisboa, Portugal, 4University, Pathology, Freiburg, Germany
18 | www.digitalpathology2016.org www.digitalpathology2016.org | 19
SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016 SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016
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SY07 SYMPOSIUM
3:30 PM–5:00 PMRoom: Robert Koch
Imaging Technology
Chairs: J. Isola (Tampere, Finland)J. Klossa (Châtillon, France)
3:30 PM–3:45 PM SY07.01 Infl uence of display characteristics on clinical performance in digital pathology T. Kimpe*¹ (Belgium), A. Avanaki², K. Espig², J. Rostang¹, G. Van Hoey¹, A. Xthona²¹Barco, Healthcare Division, Kortrijk, Belgium,²Barco, Healthcare Division, Beaverton,
Oregon, United States
3:45 PM–4:00 PM SY07.02 Optimizing optical and digital resolution for brightfi eld whole slide scanning J. Isola* (Finland), O. Ylinen, T. Tolonen, P. TolonenUniversity of Tampere, BioMediTech, Tampere, Finland
4:00 PM–4:15 PM SY07.03 Hematoxylin counterstain to simplify whole slide scanning of immunofl uorescence stains J. Isola* (Finland), T. Tolonen, P. Tolonen, O. YlinenUniversity of Tampere, BioMediTech, Tampere, Finland
4:15 PM–4:30 PM SY07.04 Digital microscopy versus conventional microscopy in assessment of jejune intraepithelial lymphocytes V. T. Moldovan*¹ (Romania), L. Ali¹, C. Mehotin², A. Bucataru², I. Cozea², M. Sajin², A. Lazaroiu²¹Victor Babes National Institute of Pathology, Pathology, Bucuresti,
Romania,²Bucharest Emergency University Hospital, Surgical Pathology,
Bucuresti, Romania
4:30 PM–4:45 PM SY07.05 Microanatomical analysis and quantifi cation of plasma cell niche interactions in the bone marrowS. Zehentmeier1, Z. Cseresnyes1,2, K. Holzwarth1, J. Stefanowski³, D. Reismann², R. Niesner², A. Radbruch4, A. Hauser-Hankeln*5 (Germany)¹Deutsches Rheumaforschungszentrum, Immunodynamics, Berlin, Germany,
²Deutsches Rheumaforschungszentrum, Biophysical Analytics, Berlin, Germany,
³Charité – Universitätsmedizin Berlin, 4Deutsches Rheumaforschungszentrum,
Cell Biology, Berlin, Germany, 5Deutsches Rheumaforschungszentrum,
Medizinische Klinik m.S. Rheumatologie und Klinische Immunologie,
Berlin, Germany
5:00 PM–5:30 PM COFFEE BREAK
2:45 PM–3:00 PM SY05.06 A workfl ow for computer-aided cytology in whole slide images: application in fi ne-needle aspiration thyroid cytologyR. Mormont¹, J.-M. Begon¹, C. Degand²,N. D’Haene², I. Salmon², R. Marée*¹ (Belgium)¹University of Liège, Systems and Modeling, Liege, Belgium,
²ULB Erasme Hospital, Pathology Department, Brussels, Belgium
3:00 PM–3:30 PM COFFEE BREAK
SY06 SYMPOSIUM
3:30 PM–5:00 PMRoom: Hörsaal
Diagnostic Advances
Chairs: V. Della Mea (Udine, Italy)M. Gadermayr (Aachen, Germany)
3:30 PM–3:45 PM SY06.01 An integrated environment for tissue morphometrics and analytics T. Qaiser* (United Kingdom), K. Sirinukunwattana, N. RajpootUniversity of Warwick, Department of Computer Science, Coventry, United Kingdom
3:45 PM–4:00 PM SY06.02 Evolution and revolution in contemporary pathology G. Duglio* (Italy)Cloud Pathology Group, Headquarters, Milan, Italy
4:00 PM–4:15 PM SY06.03 Semi-automatic classifi cation of histopathological images: dealing with inter-slide variations M. Gadermayr* (Germany), M. Strauch, J. Unger, P. Boor, B. M. Klinkhammer, S. Djudjaj, D. MerhofRWTH Aachen University, Aachen, Germany
4:15 PM– 4:30 PM SY06.04 Estimating liver steatosis: can artifi cial neural network and image analysis improve the accuracyI. C. Türkmen¹, A. Çapar*² (Turkey), A. Akhan¹, B. Saka¹,A. Cakir¹, S. Ramadan¹, G. B. Dogusoy³¹Istanbul Medipol University, Pathology, Istanbul, Turkey, ²Istanbul Technical
University, Informatics Institute, Istanbul, Turkey, ³Istanbul Bilim University,
Pathology, Istanbul, Turkey
4:30 PM– 4:45 PM SY06.05 Digital pathology in Italy: preliminary results from a national surveyR. Mencarelli¹, V. Della Mea*² (Italy), D. Massi³¹SIAPEC, Rovigo, Italy, ²University of Udine, Udine, Italy,
³University of Firenze, Firenze, Italy
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SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016
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SCIENTIFIC PROGRAM THURSDAY, MAY 26, 2016
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1ST FLOOR
Hörsaal
5TH FLOOR
R. Koch
GROUND FLOOR
Lounge
9:00 AM KN02 9:00 AM
Strategies and Demands for Digital
Pathology Workfl ow Integration
10:00 AMCoff ee Break
10:00 AM
SY08 SY09
Image Analysis II –
Tissue Modelling
Quality Assessment and Quality
Management
11:00 AM 11:00 AM
12:00 PM 12:00 PM
LS02
Lunch Break GE Healthcare: Global Experiences
from Implementing Omnyx
Digital Pathology
Lunch Break
1:00 PM 1:00 PM
SY10 SP02
Standardization Pecha Kucha & Science Slam
2:00 PM 2:00 PM
3:00 PMCoff ee Break
3:00 PM
SY11 SY12
Clinical Workfl ow Integration eLearning
4:00 PM 4:00 PM
5:00 PM Coff ee Break
5:00 PM
PD02
Digital Pathology Workfl ow
Integration
6:00 PM 6:00 PM
7:00 PM 7:00 PM
SOCIAL PROGRAM
Floating Science
Scientfi c Session
Keynote Lecture
Panel Discussion
ePoster Session
IHE/DICOM
Lunch Symposium
Social Program
Special Session
Other Meetings and Workshops
PD01 PANEL DISCUSSION
5:30 PM–6:30 PMRoom: Hörsaal
Imaging in Clinics and Research
Chairs: J. Lundin (Tampere, Finland)G. Kayser (Freiburg, Germany)
Panel guests: D. Racoceanu* (France) H. K. Hahn* (Germany) A. Laurinavicius* (Lithuania)
Digital imaging in pathology has undergone an exponential period of growth and expansion catalyzed by changes in imaging hardware and gains in computational processing. Whole slides can be imaged in fl uorescence or by use of multispectral imaging systems. New imaging technologies such as Raman spectroscopy and Hyperspectral imaging off er diff erent views into tissue. Deep learning algorithms change the game in recognition of pathological changes. For the next future, the representation of local information (position information on slide/tissue) with Omics- information is essential. Are we ready for this development? What is missing? How we can integrate clinical, genetic, tissue and image data in clinical care and research settings? The roundtable will discuss the main developments and experiences in the last years.
OTHER MEETINGS AND WORKSHOPS
6:30 PM–7:30 PMRoom: Lounge (Ground fl oor)
ECDP Council Meeting
SOCIAL PROGRAM
7:30 PM–10:00 PMCharité
Guided Tour through Charité
22 | www.digitalpathology2016.org www.digitalpathology2016.org | 23
SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016 SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016
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KN02 KEYNOTE LECTURE
9:00 AM–10:00 AMRoom: Hörsaal
Keynote II
Chair: K. Zatloukal (Graz, Austria)
KN02.01 Strategies and demands for digital pathology workfl ow integration L. Pantanowitz* (United States)University of Pittsburgh, Medical Center, Pittsburgh, United States
10:00 AM–10:30 AM COFFEE BREAK
SY08 SYMPOSIUM
10:30 AM–12:00 PMRoom: Hörsaal
Image Analysis II – Tissue Modelling
Chairs: F. Feuerhake (Hannover, Germany)J. Lundin (Tampere, Finland)
10:30 AM–10:45 AM SY08.01 Use of digital image analysis for outcome prediction in breast cancer I. Roxanis*¹ (United Kingdom), R. Colling²¹Oxford University Hospital and NIHR Biomedical Research Centre, Oxford, United
Kingdom, ²University of Oxford, Oxford, United Kingdom
10:45 AM–11:00 AM SY08.02 Image analysis approach to distinguish lobular structures in the mammary gland from well-diff erentiated breast cancer with tubule formation A. Grote* (Germany), N. S. Schaadt, F. FeuerhakeHanover Medical School, Institute for Pathology, Hanover, Germany
11:00 AM–11:15 AM SY08.03 Automated Ki67 hotspot detection for breast cancer biopsies D. Pilutti*¹ (Italy), E. Pegolo², F. La Marra¹, V. Della Mea¹, C. Di Loreto¹¹University of Udine, Udine, Italy, ²Azienda Ospedaliera Universitaria Udine,
Udine, Italy
11:15 AM–11:30 AM SY08.04 Automatic detection of suspicious regions in whole slide imaging for patients with Barrett’s Esophagus M. Lucas*¹ (Netherlands), I. Jansen1,2, M. van der Wel3,4, S. Meijer4, D. Savci Heijink4, T. van Leeuwen¹, H. Marquering1,5, D. de Bruin1,2
¹AMC, Biomedical Engineering and Physics, Amsterdam, Netherlands, ²AMC, Urology,
Amsterdam, Netherlands, ³AMC, Gastroenterology, Amsterdam, Netherlands, 4AMC,
Pathology, Amsterdam, Netherlands, 5AMC, Radiology, Amsterdam, Netherlands
11:30 AM–11:45 AM SY08.05 Automated measurement of the density of vessels on whole slide images of paediatric brain tumours C. Deroulers*¹ (France), V. Dangouloff -Ros², M. Badoual¹, P. Varlet³, N. Boddaert²¹Univ Paris Diderot-Paris 7, Physics Dept, Lab. IMNC, Orsay CEDEX, France,
²Hopital Necker-Enfants Malades, Department of Pediatric Radiology, Paris, France,
³Centre Hospitalier Sainte-Anne, Department of Nauropathology, Paris, France
11:45 AM–12:00 PM SY08.06 Micrometastasis detection guidance by whole-slide image texture analysis in colorectal lymph nodes R. Venâncio*¹ (France), B. Ben Cheikh¹, A. Coron¹, E. Saegusa-Beecroft2,3, J. Machi2,3, L. Bridal¹, D. Racoceanu¹, J. Mamou4
¹Sorbonne Universités, UPMC Univ Paris 06, CNRS, INSERM, Laboratoire d’Imagerie
Biomédicale (LIB), Paris, France, ²Department of Surgery, University of Hawaii and
Kuakini Medical Center, Honolulu, Hawaii, United States, ³Department of Pathology,
Kuakini Medical Center, Honolulu, Hawaii, United States, 4Lizzi Center for Biomedical
Engineering, Riverside Research, New York, United States
SY09 SYMPOSIUM
10:30 AM–12:00 PMRoom: Robert Koch
Quality Assessment and Quality Management
Chairs: D. Ameisen (Paris, France)N. Zerbe (Berlin, Germany)
10:30 AM–10:45 AM SY09.01 Image quality requirements for clinical and research applications N. Zerbe*1,2,3 (Germany), D. Heim¹, T. Wetzel¹, M. Domhardt1,2, S. Wienert3,4, A. Alekseychuk5, K. Schlüns¹, P. Hufnagl1,2,3
¹Charité – Universitätsmedizin Berlin, Institute of Pathology, Berlin, Germany
²Charité – Universitätsmedizin Berlin, Centralized Biomaterialbank (ZeBanC), Berlin,
Germany, ³University of Applied Sciences – HTW Berlin, Dept. Applied Informatics,
Berlin, Germany, 4VMscope GmbH, Berlin, Germany, 5Vision in X industrial imaging
GmbH, Berlin, Germany
10:45 AM–11:00 AM SY09.02 Blur quantifi cation of medical images: DICOM media, whole slide images, generic images and videos D. Ameisen*1,2 (France), J. Auger-Kantor¹, E. Ameisen¹¹Paris Biotech Santé, Université Paris Descartes, Paris, France,
²IRIF, CNRS and Université Paris Diderot, Paris, France
11:00 AM–11:15 AM SY09.03 Comparison display resolution on user impact for digital pathology C. Marchessoux*¹ (Belgium), A. Nave Dufour¹, K. Espig², S. Monaco³, A. Palekar³, L. Pantanowitz³¹BARCO, Kortrijk, Belgium, ²BARCO, Beaverton, United States,
³UPMC, Pittsburgh, United States
24 | www.digitalpathology2016.org www.digitalpathology2016.org | 25
SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016 SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016
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11:15 AM–11:30 AM SY09.04 Effi cient, unbiased quality assurance of automated tissue analysis applicable to daily pathology practice A. Rasmusson*¹ (Lithuania), B. Plancoulaine², P. Herlin³, A. Laurinavicius1,3
¹National Center of Pathology, affi liate of Vilnius University Hospital, Santariskiu
Clinics, Vilnius, Lithuania, ²Path-Image/BioTiCla, University of Normandy Caen, Caen,
France, ³Faculty of Medicine, Vilnius University, Vilnius, Lithuania
11:30 AM–11:45 AM SY09.05 The benefi ts of digital pathology in the assessment of HER2 ISH in a national external quality assessment scheme K. Sheehan*¹ (Ireland), M. Ibrahim², E. Kay¹, S. Parry², A. O‘Grady¹¹Royal College of Surgeons in Ireland, Department of Pathology, Beaumont Hospital,
Dublin, Ireland, ²UK NEQAS Immunohistochemistry and InSitu Hybridisation,
Finsbury Business Centre, 40 Bowling Green Lane, London EC1R 0NE, United
Kingdom
11:45 AM–12:00 PM SY09.06 Application of medical information system for image-based second opinion consultations – Georgian experience E. Kldiashvili* (Georgia)Georgian Telemedicine Union (Association), Tbilisi, Georgia
12:15 PM–1:15 PM LUNCH BREAK
LS02 LUNCH SYMPOSIUM
12:15 PM–1:15 PMRoom: Robert Koch
GE Healthcare: Global Experiences from Implementing
Omnyx Digital Pathology
Chair: L. Pantanowitz (Pittsburgh, United States)
12:15 PM–12:45 PM LS02.01 Impacting clinical, workfl ow & economic outcomes with digital pathology L. Pantanowitz* (United States)Pittsburgh, United States
12:45 PM–1:15 PM LS02.02 Synlab – Experiences and implementation of routine reporting with digital pathology across the lab network J. A. Asenjo* (Spain)Madrid, Spain
SY10 SYMPOSIUM
1:30 PM–3:00 PMRoom: Hörsaal
Standardization
Chairs: M. García-Rojo (Jerez de la Frontera, Spain)G. Haroske (Dresden, Germany)
1:30 PM–1:45 PM SY10.01 A review on international guidelines for digital pathology M. García-Rojo* (Spain)Hospital de Jerez de la Frontera, Pathology Department, Jerez de la Frontera, Spain
1:45 PM–2:00 PM SY10.02 Optimal image data compression for whole slide images J. Isola* (Finland)University of Tampere, BioMediTech, Tampere, Finland
2:00 PM–2:15 PM SY10.03 Anatomic pathology structured report under FHIR T. Schrader* (Germany), J. LibrammUniversity of Applied Sciences Brandenburg, Informatics and Media, Brandenburg,
Germany
2:15 PM–2:30 PM SY10.04 Color calibration in digital pathology: the clinical impact of a novel test object E. Clarke*1,2 (United Kingdom), C. Revie³, D. Brettle², R. Wilson³, C. Mello-Thoms4, D. Treanor1,2
¹University of Leeds, Leeds Institute of Cancer and Pathology, Leeds, United
Kingdom, ²Leeds Teaching Hospitals NHS Foundation Trust, Department of
Histopathology, Leeds, United Kingdom, ³FFEI Limited, Hemel Hempstead, United
Kingdom, 4University of Sydney, Faculty of Health Sciences, Sydney, Australia
2:30 PM–2:45 PM SY10.05 Standardization of pathology whole slide images according to DICOM 145 supplement and storage in PACS M. García-Rojo*¹ (Spain), A. Sanchez², G. Bueno³, D. de Mena¹¹Hospital de Jerez de la Frontera, Pathology Department, Jerez de la Frontera,
Spain, ²Hospital de Jerez de la Frontera, IT Department, Jerez de la Frontera, Spain,
³Universidad de Castilla-La Mancha, School of Industrial Engineering, VISILAB Group,
Ciudad Real, Spain
2:45 PM–3:00 PM SY10.06 Typing, grading, staging – the ultimate goals of pathology reports modelled in HL7V3/CDA G. Haroske*¹ (Germany), F. Oemig²¹Dresden-Friedrichstadt General Hospital, Institute of Pathology, Dresden, Germany,
²T-Systems, Frankfurt, Germany
SP02 SPECIAL SESSION
1:30 PM–3:00 PMRoom: Robert Koch
Pecha Kucha & Science Slam
Chairs: T. Schrader (Brandenburg, Germany)A. Bucur (Eindhoven, Netherlands)
3:00 PM–3:30 PM COFFEE BREAK
26 | www.digitalpathology2016.org www.digitalpathology2016.org | 27
SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016 SCIENTIFIC PROGRAM FRIDAY, MAY 27, 2016
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SY11 SYMPOSIUM
3:30 PM–5:00 PMRoom: Hörsaal
Clinical Workfl ow Integration
Chairs: L. Pantanowitz (Pittsburgh, United States)P. van Diest (Utrecht, Netherlands)
3:30 PM–3:45 PM SY11.01 Choosing and implementing the correct whole slide imaging system P. Branders* (Belgium), T. Tousseyn, B. WeynandUniversity Hospital Leuven, Pathology, Leuven, Belgium
3:45 PM–4:00 PM SY11.02 The eff ects of digital workfl ow support and workfl ow control for the performance of routine pathology G. Haroske* (Germany), M. MörzDresden-Friedrichstadt General Hospital, Institute of Pathology, Dresden, Germany
4:00 PM–4:15 PM SY11.03 Integration of externalized decision models in the defi nition of workfl ows for digital pathology J. van Leeuwen* (Netherlands), A. Ibrahim, A. BucurPhilips Research Europe, Eindhoven, Netherlands
4:15 PM–4:30 PM SY11.04 The role of the technicians in the digital pathology implementation. Searching optimization E. Alcaraz-Mateos*¹ (Spain), I. Tortosa-Martinez², C. Alcolea-Guardiola², S. Estevez-Ligero², A. Abellan-Palazon², A. Kundisova³, A. Nieto-Olivares¹, A. Chaves-Benito¹¹Morales Meseguer University Hospital, Pathology Department, Murcia, Spain,
²Morales Meseguer University Hospital (Technician), Pathology Department, Murcia,
Spain, ³University of Bratislava, Faculty of Medicine, Bratislava, Slovakia
4:30 PM–4:45 PM SY11.05 Solution for the optimization of pathology case distribution leveraging fl exible defi nition of policies A. Bucur*¹ (Netherlands), J. van Leeuwen¹, R. Vdovjak²¹Philips Research Europe, Eindhoven, Netherlands ,²Philips Healthcare, Eindhoven,
Netherlands
SY12 SYMPOSIUM
3:30 PM–5:00 PMRoom: Robert Koch
eLearning
Chairs: I. Klempert (Berlin, Germany)N. Kavantzas (Athens, Greece)
3:30 PM–3:45 PM SY12.01 The impact of introducing virtual slides as a replacement for PowerPoint presentations in the students’ microscopy labs A. Vaduva*¹ (Romania), R. Cornea1,2, M. Cornianu1,2, I. Mihai1,2, A. Muresan1,2, O. Vita¹, M. Derban¹, A. Jurescu¹, A. Gheju1,2, S. Taban1,2, C. Lazureanu1,2, C. Duta2,3, F. Lazar2,3, A. Dema1,2
¹University of Medicine and Pharmacy „Victor Babes“, Morphopathology, Timisoara,
Romania, ²County Emergency Hospital, Timisoara, Romania, ³University of Medicine
and Pharmacy „Victor Babes“, Surgery, Timisoara, Romania
3:45 PM–4:00 PM SY12.02 Development of an android based interactive guide for the “Berliner Medizinhistorisches Museum der Charité” I. Klempert*¹ (Germany), T. Arndt², T. Schnalke³, P. Hufnagl1,2,4, N. Zerbe1,2,4
¹Charité – Universitätsmedizin Berlin, Institute of Pathology, Berlin, Germany,
²University of Applied Sciences – HTW Berlin, Dept. Applied Informatics, Berlin,
Germany, ³Berliner Medizinhistorisches Museum, Charité – Universitätsmedizin
Berlin, Berlin, Germany, 4Charité – Universitätsmedizin Berlin, Centralized
Biomaterialbank (ZeBanC), Berlin, Germany
4:00 PM–4:15 PM SY12.03 Open access publication in pathology: advantages, constraints and new tools R. Carvalho*¹ (Portugal), S. Borkenfeld², K. Kayser³¹Central Lisbon Hospital Center, Department of Pathology, Lisbon,
Portugal, 2International Academy of Telepathology, Heidelberg, Germany,
³Charité, Berlin, Germany
4:15 PM– 4:30 PM SY12.04 CyTest – a new platform for training and testing in cytopathology L. Lianas*¹ (Italy), M. E. Piras¹, E. Musu¹, S. Podda¹, F. Frexia¹, E. Ovcin², G. Bussolati², G. Zanetti¹¹CRS4 – CENTER FOR ADVANCED STUDIES, RESEARCH AND DEVELOPMENT IN
SARDINIA, Data Intensive Computing, Pula, Italy, ²COREP, Member of the CyTest
Project, Torino, Italy
4:30 PM– 4:45 PM SY12.05 Comparative analyses based on WSI view paths recorded during multiple practical exams in oral pathology S. Walkowski*¹ (Poland), M. Lundin², J. Szymas³, J. Lundin²¹Poznan University of Technology, Faculty of Computing, Poznan, Poland, ²University
of Helsinki, Institute for Molecular Medicine Finland FIMM, Helsinki, Finland, ³Poznan
University of Medical Sciences, Department of Clinical Pathology, Poznan, Poland
28 | www.digitalpathology2016.org www.digitalpathology2016.org | 29
SCIENTIFIC PROGRAM SATURDAY, MAY 28, 2016
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4:45 PM– 5:00 PM SY12.06 Virtual patients and Serious Games in Medicine P. Siregar* (France), N. JulenIntegrative BioComputing, Centre d’Aff aires Buro Club, Chantepie, France
5:00 PM–5:30 PM COFFEE BREAK
PD02 PANEL DISCUSSION
5:30 PM–6:30 PMRoom: Hörsaal
Digital Pathology Workfl ow Integration
Chairs: P. van Diest (Utrecht, Netherlands)L. Pantanowitz (Pittsburgh, United States)
PD02.01 Panel guests: V. Della Mea* (Italy) M. García-Rojo* (Spain) P. Hufnagl* (Germany)
After the digitalization of glass slides, the digitalization of the workfl ow in pathology departments is the current challenge. Diff erent aspects should be covered by the Pathology Laboratory Information Systems and accompanying system: viewing, managing of slides, laboratory workfl ow tracking, request for special stainings, collaboration, education, supervision and of course the integration of image processing and analysis. But the main issues are under discussion: Is it possible/appropriate to standardize all diff erent aspects in digital pathology? How to integrate newest technologies in workfl ow – with or without standards? What are the requirements of users? What is best practice? How much technology do we really need? Is a stepwise introduction of digital pathology a realistic option or is a complete switch to whole slide images the best choice?
SOCIAL PROGRAM
7:30 PM–10:30 PMHaus der Kulturen
der Welt
Floating Science
Focused View. On the Confi guration of Medical Body images in Wax Models and Specimens T. Schnalke* (Germany)Berliner Medizinhistorisches Museum, Charité – Universitätsmedizin Berlin,
Berlin, Germany
2ND FLOOR
R. Virchow
1ST FLOOR
B. v. Langenbeck
9:00 AM SY13 SY14 9:00 AM
Molecular & Integrative PathologyImage Analysis III –
Graphs & Topology
10:00 AM 10:00 AM
Coff ee Break
11:00 AM PD03 11:00 AM
Integrative Pathology
and Translational Medicine
12:00 PM SP03 12:00 PM
Closing and Farewell
Scientfi c Session
Keynote Lecture
Panel Discussion
ePoster Session
IHE/DICOM
Lunch Symposium
Social Program
Special Session
Other Meetings and Workshops
30 | www.digitalpathology2016.org www.digitalpathology2016.org | 31
SCIENTIFIC PROGRAM SATURDAY, MAY 28, 2016 SCIENTIFIC PROGRAM SATURDAY, MAY 28, 2016
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SY13 SYMPOSIUM
9:00 AM–10:00 AMRoom: Rudolf Virchow
Molecular & Integrative Pathology
Chairs: F. Klauschen (Berlin, Germany)G. Mutter (Boston, United States)
9:00 AM–9:15 AM SY13.01 Semi-automatic quantifi cation of mRNA expression in whole-slide tissue images V. Meas-Yedid*1,2 (France), O. Fuica¹, M. Boukerroucha³, S. El Guendi³, S. Dallongeville¹, J.-C. Olivo-Marin¹, C. Josse³, R. Marée³¹Institut Pasteur, Cell Biology and Infection, Paris, France, ²CNRS, UMR 3691, Paris,
France, ³GIGA-Research, GIGA-Cancer, University of Liege, Liege, Belgium
9:15 AM–9:30 AM SY13.02 Diagnosis of the chronic lymphocytic leukemia (CLL) using a Raman-based scanner optimized for blood smear analysis (M3S Project) M. Fere*¹ (France), L. H. Liu¹, C. Gobinet¹, A. Beljebbar¹, V. Untereiner¹, J.-F. Angiboust¹, M. Manfait¹, D. Gheldof², H. Jacquemin², S. Walbrecq², E. Cornet³, X. Troussard³, B. Chatelain², J. Angelo4, M. Chollat5, J. Klossa5, O. Piot¹¹MEDyC CNRS UMR 7369, UFR de Pharmacie, Reims, France, ²CHU Dinant Godinne,
Namur, Belgium, ³CHU Caen, Caen, France, 4CMM-ARMINES, Fontainebleau, France, 5TRIBVN, Châtillon, France
9:30 AM–9:45 AM SY13.03 Raman spectroscopy-based cancer diagnostic platform for pathology classifi cation in Barrett’s Oesophagus and its integration into clinic M. Isabelle*¹ (United Kingdom), O. Old¹, G. Lloyd¹, K. Lau², J. Dorney³, A. Lewi 4, G. Thomas4, N. Shepherd¹, H. Barr¹, I. Bell², N. Stone³, C. Kendall¹¹Biophotonics Research Unit, Gloucestershire Hospitals NHS Foundation Trust,
Gloucester, United Kingdom, ²Spectroscopy Products Division, Renishaw plc,
Wotton-under-Edge, United Kingdom ,³Biomedical Spectroscopy, School of Physics,
University of Exeter, Exeter, United Kingdom, 4Department of Cell and Developmental
Biology, University College London, London, United Kingdom
9:45 AM–10:00 AM SY13.04 Retained PTEN expression preferentially identifi es mismatch repair-profi cient breast cancers N. Fusco*1,2 (Italy), L. Runza¹, G. Ercoli¹, D. Gambini³, C. Blundo4, L. Despini4, M. Giroda4, S. Bosari1,2
¹Fondazione IRCCS Ca Granda – Ospedale Maggiore Policlinico, Division of Pathology,
Milan, Italy, ²University of Milan, Department of Pathophysiology and Organ
Transplantation, Milan, Italy, ³Fondazione IRCCS Ca Granda – Ospedale Maggiore
Policlinico, Division of Oncology, Milan, Italy, 4Fondazione IRCCS Ca Granda –
Ospedale Maggiore Policlinico, Breast Surgery Unit, Milan, Italy
SY14 SYMPOSIUM
9:00 AM–10:30 AMRoom: Bernhard von Langenbeck
Image Analysis III – Graphs & Topology
Chairs: N. Grabe (Heidelberg, Germany)K. Nakane (Osaka, Japan)
9:00 AM–9:15 AM SY14.01 Computational topology based quantifi cation of hepatocytes nuclei in lipopolysaccharide-induced liver injury in mice R. Rojas Moraleda*1,2 (Germany), W. Xiong³, N. Valous¹, L. Salinas², K. Breitkopf-Heinlein4, S. Dooley4, I. Zoernig¹, D. W. Heermann³, D. Jäger¹¹National Center for Tumor Diseases, Tumor Immunology, Heidelberg, Germany,
²Technical University Federico Santa María, Department of Informatics, Valparaiso,
Chile, ³Heidelberg University, Institute for Theoretical Physics, Heidelberg, Germany, 4Heidelberg University, Department of Medicine II, Faculty of Medicine at Mannheim,
Mannheim, Germany
9:15 AM–9:30 AM SY14.02 A graph-based digital pathology approach to describe lymphocyte clustering patterns after renal transplantation N. S. Schaadt*¹ (Germany), A. Uvarovskii², M. Meyer-Hermann2,3, R. Schönmeyer4, N. Brieu4, J. H. Bräsen¹, W. Gwinner 5, F. Feuerhake¹¹Institute for Pathology, Hannover Medical School, Hannover, Germany,
²Helmholtz Centre for Infection Research, Systems Immunology and Integrated
Centre of Systems Biology, Braunschweig, Germany, ³Institute for Biochemistry,
Biotechnology and Bioinformatics, TU Braunschweig, Braunschweig, Germany, 4Defi niens AG, Munich, Germany, 5Clinic for Nephrology, Hannover Medical School,
Hannover, Germany
9:30 AM–9:45 AM SY14.03 Graph-based approach for spatial heterogeneity analysis in tumor microenvironment B. Ben Cheikh*¹ (France), C. Bor-Angelier², D. Racoceanu¹¹Sorbonne Universités, UPMC Univ Paris 06, CNRS, INSERM, Laboratoire dImagerie
Biomedicale (LIB), Paris, France, ²Unicancer – Rhône Alpes Auvergne, Centre Jean
Perrin – Service de Pathologie, Clermont Ferrand, France
9:45 AM–10:00 AM SY14.04 Fractal behavior of Gleason and Srigley grading systems M. S. Serbanescu*¹ (Romania), R. M. Plesea², O. T. Pop³, C. Bungardean4, I. E. Plesea²¹University of Medicine and Pharmacy of Craiova, Pathology, Medical Informatics,
Craiova, Romania, ²University of Medicine and Pharmacy of Craiova, Pathology,
Craiova, Romania, ³Kings College London, Institute of Liver Studies, London, United
Kingdom, 4Municipal Clinical Hospital, Cluj-Napoca, Pathology, Cluj-Napoca,
Romania
32 | www.digitalpathology2016.org www.digitalpathology2016.org | 33
SCIENTIFIC PROGRAM SATURDAY, MAY 28, 2016 SCIENTIFIC PROGRAM SATURDAY, MAY 28, 2016
SCIE
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10:00 AM–10:15 AM SY14.05 Classifi cation of degree of diff erentiation of colorectal neoplasm by changes in the Betti number K. Nakane*¹ (Japan), A. Takiyama²¹Osaka University, Medicine, Suita, Japan, ²Hokkaido University Graduate School
of Medicine,, Department of Cancer Pathology, Sapporo, Japan
10:15 AM–10:30 AM SY14.06 Deep convolutional neural networks for histological image analysis in gastric carcinoma whole slide images H. Sharma*¹ (Germany), N. Zerbe², I. Klempert², O. Hellwich¹, P. Hufnagl²¹Technical University Berlin, Computer Vision and Remote Sensing, Berlin, Germany,
²Charité – Universitätsmedizin Institute of Pathology, Digital Pathology and IT,
Berlin, Germany
10:30 AM–11:00 AM COFFEE BREAK
PD03 PANEL DISCUSSION
11:00 AM–12:00 PMRoom: Bernhard von Langenbeck
Integrative Pathology and Translational Medicine
Chairs: M. Dietel (Berlin, Germany)G. Mutter (Boston, United States)
PD03.01 Panel guests: F. Klauschen* (Germany) G. Bueno* (Spain) M. Hansmann* (Germany)
While conventional histomorphological techniques are the solid basis of pathological diagnostics, molecular “omics” approaches and digital/computational methods are starting to transform pathology. Some proponents of these novel techniques even prognosticate that they will one day replace classical histomorphological techniques whereas others believe that the molecular and digital “hype” will not live up to their promise. A future solution of this controversy may lie in an integration of these diff erent approaches that combines the capability of histopathology to interpret complex morphological patterns with computational approaches to quantify tissue features and molecular techniques that allow to assess the mechanistic basis of disease. The roundtable intends to discuss the challenges of this integration process with a focus on how such an “integrative pathology” may also facilitate the translation of basic research fi ndings into predictive diagnostics and precision medicine.
SP03 SPECIAL SESSION
12:00 PM–1:00 PMRoom: Hörsaal
Closing Ceremony/Farewell
Chairs: K. Kayser (Heidelberg, Germany)P. Hufnagl (Berlin, Germany)
34 | www.digitalpathology2016.org www.digitalpathology2016.org | 35
ePOSTER SESSIONS THURSDAY, MAY 26, 2016 ePOSTER SESSIONS THURSDAY, MAY 26, 2016
ePO
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PS01 ePOSTER SESSION I
1:30 PM–3:00 PMRoom:
Rudolf Virchow
Molecular Pathology, Integrative Pathology, Knowledge
Formalization and Modeling, Imaging Technology,
eLearning, Telepathology
Chairs: J. Slodkowska (Warsaw, Poland)M. Vyberg (Aalborg, Denmark)
1:30 PM–1:37 PM PS01.01 Application of Raman microscopy for the diagnosis of the chronic lymphocytic leukemia (CLL) M. Fere*¹ (France), L. H. Liu¹, C. Gobinet¹, A. Beljebbar¹, V. Untereiner¹, J.-F. Angiboust¹, M. Manfait¹, D. Gheldof², H. Jacquemin², S. Walbrecq², E. Cornet³, X. Troussard³, B. Chatelain², J. Angelo4, M. Chollat5, J. Klossa5, O. Piot¹¹MEDyC CNRS UMR 7369, UFR de Pharmacie, Reims, France, ²CHU Dinant Godinne,
Namur, Belgium, ³CHU Caen, Caen, France, 4CMM-ARMINES, Fontainebleau, France, 5TRIBVN, Châtillon, France
1:37 PM–1:44 PM PS01.02 Features of an expression of smooth muscle actin by muscle cells of arterioles and venules of ureter and urinary bladder of newborns in modeling chronic intrauterine hypoxia I. Gorianikova* (Ukraine), I. Sorokina, M. MyroshnychenkoKharkiv National Medical University, Kharkiv, Ukraine
1:44 PM–1:51 PM PS01.03 Apoptotic activity of cells of thymus and spleen in children born to women who led an unhealthy lifestyle I. Gorianikova* (Ukraine), I. Sorokina, M. MyroshnychenkoKharkiv National Medical University, Kharkiv, Ukraine
1:51 PM–1:58 PM PS01.04 Correlation Analysis of the Feto-Placental Pramameters ans Intrauterine Groth Retardation I. Gorianikova*¹ (Ukraine), O. Kononenko², O. Zinchenko², O. Antonova²¹Kharkiv National Medical University, Kharkiv, Ukraine,
²GI‘Lugansk State Medical University, Lugansk, Ukraine
1:58 PM–2:05 PM PS01.05 Morphological features of pregnancy of uterine leiomyomas I. Gorianikova*¹ (Ukraine), O. Reshetnikova², E. Burgelo²¹Kharkiv National Medical University, Kharkiv, Ukraine, ²GI ‘Lugansk State Medical
University, Lugansk, Ukraine
2:05 PM–2:12 PM PS01.06 Morphological patterns of the placenta remodeling in cases of IGUR at 20–25 weeks of gestation I. Gorianikova*¹ (Ukraine), O. Kononenko², O. Teleshova²¹Kharkiv National Medical University, Kharkiv, Ukraine, ²GI ‘Lugansk State Medical
University, Lugansk, Ukraine
2:12 PM–2:19 PM PS01.07 An integrated framework for histological image data analytics A. Homeyer* (Germany), H. Kost, H. K. HahnFraunhofer MEVIS, Bremen, Germany
2:19 PM–2:26 PM PS01.08 Experiments in extracting digital slides from video V. Della Mea* (Italy), M. Turetta, M. Nobile, D. PiluttiUniversity of Udine, Udine, Italy
2:26 PM–2:33 PM PS01.09 Virtual microscopy new, old, out, or just a part of education I. Klempert* (Germany), K. JöhrensInstitute of Pathology, Charité, Berlin, Germany
2:33 PM–2:40 PM PS01.10 Identifying cost of archiving service of digital pathology A. Imad* (United Kingdom)University of Bradford, Bradford, United Kingdom
2:40 PM–2:47 PM PS01.11 Telepathology a useful method in the diagnosis digestive biopsies with rare entities. Case presentation of a collagenous gastritis V. T. Moldovan*¹ (Romania), L. Ali¹, B. Gabriel²¹Victor Babes National Institute of Pathology, Pathology, Bucuresti, Romania,
²INCD V. Babes, Bucuresti, Romania
2:47 PM–2:54 PM PS01.12 The use of smartphones as adjuvant tool in cervical cytologic diagnosis L. Ali*¹ (Romania), V. Moldovan¹, M. Sajin²¹Victor Babes National Institute of Pathology, Pathology, Bucharest, Romania,
²Bucharest University Emergency Hospital, Pathology, Bucharest, Romania
PS02 ePOSTER SESSION II
3:30 PM–5:00 PMRoom:
Rudolf Virchow
Virtual Microscopy, Image Analysis, Computer Aided
Diagnosis
Chairs: A. Huisman (Utrecht, Netherlands)K. Zatloukal (Graz, Austria)
3:30 PM–3:37 PM PS02.01 The reproducibility index of pathological diagnosis and rare cases. The results of the on-line diagnostic competition Final diagnosis A. Kudaybergenova*¹ (Russian Federation), A. Artemyeva², A. Remez³¹Petrov Research Institute of Oncology, pathology, Saint Petersburg, Russian
Federation, ²Petrov Research Institute of Oncology, Saint Petersburg, Russian
Federation, ³ UNIM, MOSCOW, Russian Federation
36 | www.digitalpathology2016.org www.digitalpathology2016.org | 37
ePOSTER SESSIONS THURSDAY, MAY 26, 2016 ePOSTER SESSIONS THURSDAY, MAY 26, 2016
ePO
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3:37 PM–3:44 PM PS02.02 Pathology assistant (c) – game changer of pathology diagnosticA. Kudaybergenova¹, A. Remez*² (Russian Federation)¹Petrov Research Institute of Oncology, pathology, Saint Petersburg, Russian
Federation, ²UNIM, MOSCOW, Russian Federation
3:44 PM–3:51 PM PS02.03 Open source systems in digital pathology A. Dariush* (United Kingdom)University of Cambridge, Cambridge, United Kingdom
3:51 PM–3:58 PM PS02.04 Accuracy of whole slide imaging stack alignment in consecutive sections of the carotid artery M. Lucas*¹ (Netherlands), I. Jansen1,2, O. de Boer³, T. van Leeuwen¹, D. de Bruin1,2, H. Marquering1,4
¹AMC, Biomedical Engineering and Physics, Amsterdam, Netherlands,
²AMC, Urology, Amsterdam, Netherlands, ³AMC, Pathology, Amsterdam,
Netherlands, 4AMC, Radiology, Amsterdam, Netherlands
3:58 PM–4:05 PM PS02.05 Assessment of microvascular density in the neuroendocrine tumors of the pancreas: a correlation with multidetector computed tomography (MDCT) features and tumor grade A. Glotov*¹ (Russian Federation), E. Belousova², D. Kalinin¹¹A.V. Vishnevsky Surgery Institute of the Russian Ministry of Healthcare, Pathology,
Moscow, Russian Federation, ²A.V. Vishnevsky Surgery Institute of the Russian
Ministry of Healthcare, Radiology, Moscow, Russian Federation
4:05 PM–4:12 PM PS02.06 Automated quantifi cation of proliferation with automated hot-spot selection in phosphohistone H3/MART1 dual-stained melanomas P. S. Nielsen*¹ (Denmark), R. Riber-Hansen¹, H. Schmidt², T. Steiniche¹¹Aarhus University Hospital, Department of Pathology, Aarhus, Denmark,
²Aarhus University Hospital, Department of Oncology, Aarhus, Denmark
4:12 PM–4:19 PM PS02.07 Application of Ki-67 analysis in a distributed computing infrastructure M. Strutz*¹ (Germany), B. Lindequist¹, M. Witt¹, H. Heßling¹, P. Hufnagl1,2, D. Krefting¹¹University of Applied Sciences, HTW, Berlin, Germany,
²Charité – Universitätsmedizin Berlin, Institute of Pathology, Berlin, Germany
4:19 PM–4:26 PM PS02.08 Computer-assisted quantifi cation of CAIX membrane immunoreaction destined for the clear cells in renal carcinoma. A pilot study J. Slodkowska*¹ (Poland), T. Markiewicz², M. Wdowiak², B. Mlot³, W. Kozlowski¹¹Military Institute of Medicine, Pathology, Warsaw, Poland,²Warsaw University
of Technology, Warsaw, Poland,³Military Institute of Medicine, Clinic of Oncology,
Warsaw, Poland
4:26 PM–4:33 PM PS02.09 Correlations between interstitial stromal fi brillary network and disease progression in hepatitis C I. E. Plesea*¹ (Romania), C. D. Uscatu¹, M. S. Serbanescu¹, M. Indries², R. M. Plesea¹¹University of Medicine and Pharmacy of Craiova, Pathology, Craiova, Romania,
²University of Oradea, Infectious Diseases, Oradea, Romania
4:33 PM–4:40 PM PS02.10 Detection of automatic digital image analysis problems for the evaluation of immune markers in breast cancer biopsiesG. C. Orero Pastor¹, C. López¹, R. Bosch², T. Salvadó²,T. Álvaro², M. García-Rojo³, G. Bueno4, A. Korzynska5,L. Roszkowiak5, C. Callau¹, N. Navas², M. Lejeune*¹ (France)¹Hospital de Tortosa Verge de la Cinta, Molecular Biology and Research, Tortosa,
Spain, ²Hospital de Tortosa Verge de la Cinta, Pathology Department, Tortosa, Spain,
³Hospital de Jerez, Pathology Department, Jerez de la Frontera, Spain, 4VISILAB,
Engineering School, Ciudad Real, Spain, 5Nalecz Institute of Biocybernetics and
Biomedical Engineering, Laboratory of Processing Systems of Microscopic Image
Information, Warsaw, Poland
4:40 PM–4:47 PM PS02.11 Semi-automatic and automatic Ki-67 index examination in whole slide images of meningiomas T. Markiewicz*1,2 (Poland), Z. Swiderska-Chadaj², B. Grala¹, M. Lorent¹, W. Kozlowski¹¹Military Institute of Medicine, Department of Pathomorphology, Warsaw, Poland,
²Warsaw University of Technology, Warsaw, Poland
4:47 PM–4:54 PM PS02.12 Objective Ki-67 index quantifi cation in non-breast tumors preliminary data in Timisoara, Romania A. Vaduva*¹ (Romania), R. Cornea1,2, I. Mihai1,2, M. Cornianu1,2, D. Szilagyi², A. Muresan1,2, D. Anderco², C. Suciu², C. Lazureanu1,2, A. Dema1,2
¹University of Medicine and Pharmacy “Victor Babes”, Morphopathology, Timisoara,
Romania, ²County Emergency Hospital, Timisoara, Romania
4:54 PM–5:01 PM PS02.13 Patch-based nonlinear image registration for gigapixel whole slide imagesJ. Lotz¹, J. Olesch¹, N. Weiss¹, K. Breuhahn², H. K. Hahn*³ (Germany), J. Modersitzki¹¹Fraunhofer MEVIS, Lübeck, Germany, ²University Hospital Heidelberg,
Institute of Pathology, Heidelberg, Germany, ³Fraunhofer MEVIS, Bremen, Germany
38 | www.digitalpathology2016.org www.digitalpathology2016.org | 39
INDUSTRIAL EXHIBITION
LIST OF SPONSORS AND EXHIBITORS
COMPANY BOOTH NO
3DHISTECH Ltd 1
Barco GmbH 18
EXCILONE 8a
GE Healthcare 2
HalioDx 16
Hamamatsu Photonics Germany GmbH 4
Huron Digital Pathology 12
Indica Labs, Inc 8
KAIROS GmbH 9
Leica Biosystems 13
LLC BioVitrum 17
microDimensions GmbH 21
Motic Deutschland GmbH 7
Olympus Europa SE & Co.KG 11
PathXL 5
Philips 3
Precipoint 22
Sakura Finetek 15
Tissue Gnostics 10
Visiopharm 14
VMscope GmbH 9
IND
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917
1615
11
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10
Lift12Ca
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2nd floor groundfloor
8
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Media Check
8a18
groundfloor
Lecture Room 2nd floor
Hörsaal
Wandelhallen
Room"Bernhard v.Langen-beck"
1st Floor
5
4
3
Entrance
Luise
nstra
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1st/ 2nd floor session rooms
Terrace
WC
RegistrationWardrobe
Lift
Catering
Cater
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7
2Foyer
Lounge
Ground Floor
INDUSTRIAL EXHIBITION
IND
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FLOOR PLAN
40 | www.digitalpathology2016.org www.digitalpathology2016.org | 41
CONGRESS INFORMATION
CON
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ePoster ISCRoom"Emil von Behring"
Room"Paul Ehrlich"
Hörsaal
4th fl oor
INDUSTRIAL EXHIBITION
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22
21
Hörsaal
Room "RudolfVirchow"
2nd fl oor
ABSTRACTS
All abstracts will be available in a digital Book of Abstracts on the ECDP 2016 website and in the offi cial congress app.
ACT OF GOD
It is mutually agreed that in the event of total or partial cancellation of the congress due to fi re, strike, natural disaster (either threatened or actual), government regulations or incidents not caused by the organizer, which would prevent its scheduled opening or continuance, the congress may be partially postponed or terminated as a whole. In this case, participants are not entitled to reclaim refunds on no account. Participants are obliged to have civil liability insurance.
CERTIFICATE OF ATTENDANCE
All registered participants will receive a certificate of attendance together with the congress documents.
CLOAKROOM
The cloakroom is directly next to the registration desk in the foyer.
CONGRESS APP
Download your personal assistant
and get ready for ECDP 2016 in Berlin.
Create your personal agenda on your mobile device, bookmark exhibitors or speaker and browse or search the complete scientifi c program, abstracts, sponsors and exhibitors. The app will navigate your way around the exhibition and conference center. Once you have downloaded the app, you do not require internet access during operation. Nevertheless, several advanced features such as, social media integration, questions to the author (will be available onsite)
and WSI integration do require internet access. Whenever the App is connected to the internet you will automatically receive program and content updates to keep you updated all the time. You can download the congress app in the app store or on google play:
iOShttps://itunes.apple.com/de/app/
ecdp-2016-european-congress/
id1094642230?mt=8
Androidhttps://play.google.com/store/
apps/details?id=com.
ecdp.android
CONGRESS DOCUMENTS
Registration fee for participants covers: Opening ceremony and get together Admission to scientifi c sessions Admission to poster exhibition Admission to exhibition Collection of abstracts Congress bag with congress documents Certifi cate of attendance Coff ee and lunch breaks
CONGRESS LANGUAGE
The offi cial language of the congress will be English. Simultaneous translation will not be provided.
CONGRESS VENUE
Langenbeck-Virchow HausLuisenstrasse 58/5910117 Berlin, Germany
CONGRESS HOMEPAGE
www.digitalpathology2016.org
ePOSTER EXHIBITION
The ePosters will be displayed on large scale monitors in the foyer on the fourth fl oor of
42 | www.digitalpathology2016.org www.digitalpathology2016.org | 43
CONGRESS INFORMATIONCONGRESS INFORMATION
CON
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the Langenbeck-Virchow Haus until Friday, May 27, 2016 by 6:30 PM.
GASTRONOMY
During the offi cial coff ee and lunch breaks participants will be off ered snacks and beverages in the Foyer on the ground fl oor and in the room Bernhard von Langenbeck on the fi rst fl oor.
IHE/DICOM MEETINGS
The IHE WG PaLM Meetings will take place on Monday and Tuesday, May 23–24 from 9:00 AM to 5:00 PM and on Wednesday, May 25, from 9:00 AM to 3:00 PM in the room Rudolf Virchow. The DICOM WG 26 Meeting will take place on Wednesday, May 25, from 9:00 AM to 3:00 PM in the room August Bier. The IHE/DICOM Joint Meeting will take place on Wednesday, May 25, from 3:00 PM to 5:00 PM in the room Rudolf Virchow.
INDUSTRIAL EXHIBITION
The industrial exhibition is situated in the foyer on the ground fl oor, in room “Bernhard von Langenbeck” and in the Wandelhallen on the fi rst and second fl oor.
Opening Hours
Wednesday, May 25, 2016 7:00 PM–10:00 PMThursday, May 26, 2016 9:00 AM–6:00 PMFriday, May 27, 2016 9:00 AM–5:00 PM
INTERNATIONAL SCANNER CONTEST
The 3rd International Scanner Contest 2016 will take place during the ECDP 2016 as follows:
Wednesday, May 25, 2016
Room Paul Ehrlich 9:00 AM–7:00 PM
Thursday, May 26, 2016
Room Paul Ehrlich 8:00 AM–7:00 PMRoom Emil von Behring 8:00 AM–7:00 PM
Friday, May 27, 2016
Room Paul Ehrlich 8:00 AM–7:00 PMRoom Emil von Behring 8:00 AM–7:00 PM
INTERNET ACCESS
Free WIFI will be available at the congress venue. Login details will be provided on-site.
LIABILITY DISCLAIMER
The organizers cannot be held liable for any hindrance or disruption of congress proceedings arising from political, social or economic events or any other unforeseen incidents beyond their control. The organizers will accept no liability for any personal injuries sustained or for loss or damage to property belonging to congress participants, either during or as a result of the congress or during all tours and events. Registration of a participant entails acceptance of these conditions.
LOST & FOUND
A Lost & Found box will be placed at the registration desk.
MEDIA CHECK
The media check is located on the fi rst fl oor in the Speakers’ Ready Room. Speakers are kindly asked to hand over their presentation at the media check at your earliest convenience butnot later than 1 hour before the session. Please refer to the presentation guidelines on the conference website.
Opening Hours
Wednesday, May 25, 2016 3:00 PM–7:00 PMThursday, May 26, 2016 8:00 AM–6:30 PMFriday, May 27, 2016 8:00 AM–6:30 PMSaturday, May 28, 2016 8:00 AM–1:00 PM
NAME BADGE
The name badge will be the offi cial conference document and should be worn at all times in order to gain entry to the conference rooms and the exhibition halls. Admission to the conference will not be allowed without badge identifi cation. In case of lost or forgotten badges, an administration fee of € 10 will be charged.
PROGRAM CHANGES
The organizer reserves the right to make changes if necessary. No full or partial refunds are made to the attendees in the event of cancellations or other changes in the Program. Please note that changes will be posted at the registration desk and at the entrance of the session halls. Participants will be informed about the changes.
REGISTRATION DESK
The registration desk is situated in the foyer on the ground fl oor. Registration is only valid if the complete payment of the congress fee as well as of other services booked has been made. Registration on-site is possible during the entire congress within the opening hours of the registration desk. Only debit cards, credit cards and cash payment will be accepted on-site.
Opening Hours
Wednesday, May 25, 2016 10:00 AM–7:00 PMThursday, May 26, 2016 8:00 AM–6:30 PMFriday, May 27, 2016 8:00 AM–6:30 PMSaturday, May 28, 2016 8:30 AM–1:00 PM
REGISTRATION FEES
After April 27, 2016 and on site
Full registration fee € 650Student* € 400Retired person* € 400Member of DGP € 600
* Proof of current status needs to be provided along with the registration or on-site at the latest. Only then a deduction can be granted.
SOCIAL PROGRAM
Get Together
The get together will take place on Wednesday, May 25, 2016 from 7:00 PM to 9:30 PM in the exhibition halls of the congress venue.
Guided Tour Through the Charité
The guided tour through the Charité, followed by a Get Together in the Lecture Hall Ruin in the Berlin Museum of Medical History, will take place on, Thursday, May 26, 2016 from 7:30 PM to 10:00 PM (address: Charitéplatz 1, 10117 Berlin).
Floating Science
Floating science will take place on Friday, May 27, 2016 from 7:30 PM to 10:30 PM (Meeting Point at the Dock in front of the “Haus der Kulturen der Welt”, John-Foster-Dulles-Allee 10, 10557 Berlin). The evening includes a cruise on the Spree, a scientifi c presentation from Prof. Schnalke and a congress dinner.
SMOKING
Smoking is strictly prohibited in the conference venue by law.
44 | www.digitalpathology2016.org www.digitalpathology2016.org | 45
Index PRESENTING AUTHORS Index PRESENTING AUTHORS
IND
EX
IND
EX
A
Alcaraz-Mateos, E. 16, 26Alfaro, L. 16Ali, L. 35Ameisen, D. 23Asenjo, J. A. 24
B
Ben Cheikh, B. 31Bertheau, P. 13Besusparis, J. 11Botteghi, M. 13Branders, P. 26Bucur, A. 26Bueno, G. 11, 32
C
Çapar, A. 16, 18Carvalho, R. 27Clarke, E. 25
D
Dariush, A. 36Della Mea, V. 18, 28, 35Deroulers, C. 23Dietel, M. 9Duglio, G. 18
F
Fere, M. 30, 34Franchet, C. 12Fusco, N. 30
G
Gadermayr, M. 18Gahlaut, R. 11García-Rojo, M. 25, 28Glotov, A. 36Gorianikova, I. 34Grote, A. 22
H
Hahn, H. K. 11, 20, 37Hansmann, M. 32Haroske, G. 25, 26Hauser-Hankeln, A. 19Homeyer, A. 35Hufnagl, P. 9, 28
I
Imad, A. 35Isabelle, M. 30Isola, J. 19, 25
K
Kayser, K. 9, 16Kimpe, T. 19Kiszler, G. 15Klauschen, F. 32Kldiashvili, E. 24Klempert, I. 27, 35Kudaybergenova, A. 35
L
Laurinavicius, A. 17, 20Lejeune, M. 37Lianas, L. 27Lucas, M. 22, 36
M
Maas, J. 9Mallach, M. 14Marchessoux, C. 23Marée, R. 16, 18Markiewicz, T. 37Meas-Yedid, V. 17, 30Moldovan, V. T. 12, 19, 35Molnár, B. 15
N
Nakane, K. 32Nielsen, P. S. 36Nielsen, S. L. 12
P
Pantanowitz, L. 22, 24Pilutti, D. 22Plesea, I. E. 37
Q
Qaiser, T. 18
R
Racoceanu, D. 20Rasmusson, A. 24Remez, A. 36Røge, R. 12Rojas Moraleda, R. 31Roxanis, I. 22
S
Schaadt, N. S. 31Schnalke, T. 28Schrader, T. 25Seebode, C. 14Serbanescu, M. S. 31Sharma, H. 32Sheehan, K. 24Siregar, P. 14, 28Slodkowska, J. 36Stephan, C. 14Strutz, M. 36
T
Traore, L. 17
V
Vaduva, A. 27, 37van Leeuwen, J. 26Varga, V. 15Venâncio, R. 23Villa, I. 13Vukomanovic Djurdjevic, B. 11
W
Walkowski, S. 27Wienert, S. 17
Z
Zerbe, N. 9, 15, 23Zhou, C. 12
46 | www.digitalpathology2016.org www.digitalpathology2016.org |
ORGANIZER
Deutsche Gesellschaft für Pathologie e. V. (DGP)Robert-Koch-Platz 910115 Berlin, Germany
CONGRESS PRESIDENT
Prof. Dr. Peter HufnaglHead, Digital Pathology & ITInstitute of Pathology, “Rudolf-Virchow-House”Charité – Universitätsmedizin Berlin10117 Berlin, Germany
PROFESSIONAL CONGRESS ORGANIZER
MCI Deutschland GmbHMCI | Berlin Offi ceMarkgrafenstrasse 5610117 Berlin, GermanyPhone: +49 30 204590Fax: +49 30 2045950Web: www.mci-group.com
Court of jurisdiction: Local court Charlottenburg, HRB 100620B VAT ID number: DE 114406202Managing directors: Gunda Stickan, Gerrit Jessen, Andreas Laube
CONGRESS HOMEPAGE
www.digitalpathology2016.org
TIME OF PRINTING
May 9, 2016
All indications without engagement, subject to modifi cations.
IMPRINT
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