Homeopathy theories

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    MEMORY OF WATER

    The Information Medicinehypothesis

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    MEMORY OF WATER

    Water, and perhaps other polar solvents are, under certain

    circumstances, capable of storing information relating to

    substances with which they have previously been in contact,

    and subsequently transmitting this information to

    presensitised biosystems.

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    HISTORY

    Jacques Benveniste 1935-2004

    1935 Born in ParisStudied medicine at the medical school

    1967 Head of clinic at the medical faculty in1971 Discovered PAF

    Candidate for the Nobel prizeEarly 1980s:

    A medical doctor with side interest inhomeopathy joined his team.

    Jacques:He asked me if he could try my basophil

    degranulation test on some homeopathicPreparations. I said OK bu t al l you w i l lbe test ing is water.

    1988: Scientists from six laboratories in fourcountries (France, Canada, Israel andItaly) submitted an article to NATURE.

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    HISTORY

    Nature1988; 333: 816818

    Suggestion:

    Since di lu t ions need to b e accom panied by vigorous shaking for

    the effects to be observed, transm issio n of the biolog ical

    inform ation cou ld be related to the mo lecular organizat ion of

    water.

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    HISTORY2 weeks later- July 1988Nature recruited a magician to challenge Jacques experiment.

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    HISTORYMaddox J, Randi J, Stewart WW.

    High- dilution experiment is a delusion.Nature 1988; 334: 287290

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    HISTORY

    Water Memory

    WAR

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    HISTORY

    Water Memory

    WAR

    $1m prize to anyone who can provide convincing evidence

    James Randi

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    HISTORY

    Water Memory

    WAR

    Horizonconducts its own scientific experiment, to try and win his money.

    http://www.bbc.co.uk/science/horizon/2002/homeopathy.shtml

    Results are no t conc lusiv e.

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    HISTORY

    The end of the Benveniste Affair?

    Philippe Belon, Boiron, LyonJean Cumps, statistician, Catholic University of LouvainMarcel Roberfroid, coordinator, Catholic University of LouvainMadeleine Ennis, Queen's University BelfastPF Mannioni, University of FlorenceJean Ste Laudy, CERBA, ParisFred Wiegant, University of Utrecht

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    HISTORY

    Belon et al results

    LaboratoryControl

    (% degranulation)Histamine 15-19c

    (% degranulation) n p

    1 45.8 36.5 123 0.00022 50.2 47.5 312 0.065

    3 51.6 47.4 183 0.0244 47.8 35.7 154

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    How might water store

    information? Hypotheses Geometric models

    Formation of clathrates Information stored in bond lengths, angles

    Dynamic models Coherent regions displaying stable laser-like

    behaviourDel Guidice E, Preparata G, Vitiello G. Water as a free

    electric dipole laser. Phys Rev Letts 1988; 61:1085-1088

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    How might water store

    information? Hypotheses

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    How might water store

    information? HypothesesComputer simulation of hydrogen bonding in

    liquid water

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    How might water store

    information? Hypotheses

    Structure of waterH+ andOH ionsDeuterium HDO molecules

    Previously dissolved solutesDissolved gassesGaseous nanobubblesMaterials dissolved or detached from the containing vesselSolid particles and aerosols

    weakly-bound but partially-covalently linked molecular clusters containing one,two, three or four hydrogen bonds, and hydrogen ion and hydroxideion species.

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    How Homeopathic preparations

    store information? Hypotheses

    Ethanol1) Ethanol forms solutions in water that are slow to equilibrate2) Complex mixture of water-water and ethanol-ethanol clusters3) Hydrogen bonding is longer lived than in water alone4) They favour nanobubble formation

    Nieto-Draghi C, Hargreaves R, Bates SP. Structure and dynamics of water in aqueousmethanol. J Phys Condens Matter 2005; 17: S3265S3272.

    Jin F, Ye J, Hong L, Lam H, Wu C. Slow relaxation mode in mixtures of water andorganic molecules: supramolecular structures or nanobubbles? J Phys Chem B2007; 111: 22552261.

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    How Homeopathic preparations

    store information? HypothesesSilica

    Dissolved silica is capable of forming solid silicate particles with

    complementary structures (ie imprints) to dissolved solutes and

    macromolecules.

    Such particles will remember these complementary structures essentiallyforever.

    A thorough investigation into the structural differences previously reported betweenhomeopathically potentized (ie succussed and extremely diluted) and unpotentizednitric acid solutions showed that the effect was lost if different glassware was used.

    Anick DJ, Ives JA. The silica hypothesis for homeopathy:physical chemistry. Homeopathy2007; 96: 189195.

    Milgrom LR, King KR, Lee J, Pinkus AS. On the investigation of homeopathic potencies usinglow resolution NMR T2 relaxation times: an experimental and critical survey of the work ofRoland Conte et al. Br Homeopath J 2001;

    90: 513.

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    How Homeopathic preparations

    store information? HypothesesSuccussion

    May significantly increase concentrations of silicate, sodium and bicarbonate

    Increasing and decreasing (negative) pressure will be encountered so involving thecompression and stretching of the hydrogen bonded network.

    Silicate glassliquid surface: Pressure waves would not only encourage dissolutionbut may dislodge nanoparticles of silicate (or other) material.

    Elia V, Niccoli M. New physico-chemical properties of extremely diluted aqueous solutions. JTherm Anal Calorim2004; 75: 815836.

    Voeikov VL. The possible role of active oxygen in the Memory of Water. Homeopathy 2007;

    96: 196201.

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    How Homeopathic preparations

    store information? HypothesesSuccussion

    Produces long term oscillatory behaviour

    Produces hydrogen peroxide and Ozone molecules (increased potency withincreased dilution)

    Water impurities (bacterial contamination) can change during the dilution process byreactions initiated by the original active material. Different potencies have different

    Effects.Elia V, Niccoli M. New physico-chemical properties of extremely diluted aqueous solutions. JTherm Anal Calorim2004; 75: 815836.

    Voeikov VL. The possible role of active oxygen in the Memory of Water. Homeopathy 2007;

    96: 196201.

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    Normal water

    in electromagnetic field

    Clustered water

    in electromagnetic field

    Formation of Clathrates

    Evaporating monosodium phosphate IE(clustered) solution in the presence of an

    electromagnetic field.

    Lo SY, Lo A, Chong LW, Tianzhang L, Hua LH, Geng X.

    Physical properties of water with IE structures.

    Modern Physics Letters. (1996) B10:921-930.

    How might water store

    information? Hypotheses

    Th l i f

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    Thermoluminescence of

    ultramolecular dilutions of NaCl and

    LiCl Method dilutions of LiCl and NaCl in heavy water (D2O)

    cooled to 770K, bombarded with x- or -rays

    excites electrons, creates +vely charged holes

    warmed: +ve holes and excited electrons recombine generates characteristic thermoluminescence glow

    Results

    high dilutions (15c = 10-30) of LiCl and NaCl have similar

    spectrum to dilutions containing molecules of the samesubstances, and different from D2O

    likely to be due to broken H-bonds

    Thermoluminescence signature of

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    Thermoluminescence signature ofultramolecular dilutions of NaCl and

    LiCl

    Rey L. Thermoluminesence of ultra-high dilutions of lithium chloride andsodium chloride. Physica A 2003; 323:67-74

    ermo um nescence s gna ure o

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    ermo um nescence s gna ure oultramolecular dilutions of NaCl and

    LiCl

    Rey L. Thermoluminesence of ultra-high dilutions of lithium chloride andsodium chloride. Physica A 2003; 323:67-74

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