HISTOLOGI KARDIOVASKULER

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HISTOLOGI KARDIOVASKULER. SYSTEMA CIRCULATORIUS. KLASIFIKASI: SISTEM KARDIOVASKULAR PEMBULUH DARAH JANTUNG SISTEM LIMFATIK NODUS LYMPHATICUS PEMBULUH LIMFE HUBUNGAN STRUKTURAL/FUNGSIONAL: SISTEM KARDIOVASKULAR BERHUBUNGAN DENGAN SISTEM LIMFATIK HISTOLOGI: - PowerPoint PPT Presentation

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Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsHISTOLOGI KARDIOVASKULER1Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsSYSTEMA CIRCULATORIUSKLASIFIKASI:SISTEM KARDIOVASKULARPEMBULUH DARAHJANTUNGSISTEM LIMFATIKNODUS LYMPHATICUSPEMBULUH LIMFEHUBUNGAN STRUKTURAL/FUNGSIONAL:SISTEM KARDIOVASKULAR BERHUBUNGAN DENGAN SISTEM LIMFATIKHISTOLOGI:SELURUH SISTEM DIBATASI OLEH ENDOTELCopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsHUBUNGAN TIMBAL BALIK SISTEM LIMFATIK DAN SISTEM KARDIOVASKULERSISTEM LIMFATIK SISTEM KARDIO-VASKULERDUCTUS THORACICUS ET DUCTUS LYMPHATICUS DEXTER BERMUARA DALAM VENA BESAR SEBAGAI BAGIAN SISTEM PEMBULUH DARAHSISTEM KARDIOVASKULER SISTEM LIMFATIKCAIRAN LIMFE DENGAN LIMFOSIT DALAM VENULA POST-CAPILER DALAM SETIAP NODUS LYMPHATICUS SEBAGAI BAGIAN DARI SISTEM PEMBULUH DARAH, MASUK SISTEM LIMFATIK, YANG PADA AKHIRNYA DITAMPUNG DALAM KEDUA SALURAN LIMFE BESAR

Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsSYSTEMA CIRCULATORIUSJANTUNG

ARTERIA BESAR

ARTERIA SEDANG

ARTERIA KECIL

PEMBULUH KAPILER

VENA KECIL

VENA SEDANG

VENA BESAR SISTEM LIMFATIKADUCTUS THORACICUSSISTEM KARDIOVASKULARCopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsSISTEM LIMFATIKKAPILER LIMFE BUNTU KAPILER LIMFE BUNTU (vasa aferentia) (vasa aferentia)

NODUS LYMPHATICUS NODUS LYMPHATICUS PEMBULUH LIMFE BESARPEMBULUH DARAH VENAJANTUNGVasa eferentiaDUCTUS THORACICUS ET DUCTUS LYMPHATICUS DEXTERCopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsALIRAN CAIRAN LIMFECAIRAN LIMFE (CAIRAN JARINGAN)PLASMALIMFOSITPEMBULUH LIMFEDIMULAI DENGAN KAPILER LIMFE BUNTUMENAMPUNG DARI CAIRAN JARINGANNODUS LYMPHATICUSMENAMPUNG KAPILER PADA PERMUKAAN CEMBUNGPEMBULUH LIMFE LEBIH BESARMENAMPUNG DARI VASA EFERENTIA N. LYMPHATICUSPEMBULUH LIMFE BESAR MENUJU KE JANTUNGDIAMETER PEMBULUH LIMFE SEMAKIN BESARDUCTUS THORACICUS V. SUBCLAVIA SINISTRADUCTUS LYMPHATICUS DEXTER V. SUBCLAVIA DEXTRA

Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsALIRAN CAIRAN LIMFE

NODUS LYMPHATICUSARTERIVENACopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsSIRKULASI PLASMA DAN LIMFOSITSISTEM LIMFE

SISTEM KARDIO - VASKULER

Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsDINDING VASA LYMPHATICAVASA AFERENTIAMENAMPUNG CAIRAN JARINGANDIAMETER LEBIH BESAR SEDIKIT DARI KAPILER DARAHSELAPIS SEL ENDOTEL TIPISTIDAK ADA PERISITMASUK KE DALAM SINUS LYMPHATICUS DALAN NODUS LYMPHATICUSKELUAR DARI HILUS SEBAGAI VASA EFERENTIASTRUKTUR DINDING SAMA DENGAN VASA AFERENTIAMENGANGKUT CAIRAN LIMFE DENGAN LIMFOSITVASA LYMPHATICAMENERIMA BEBERAPA VASA EFERENTIA, DIAMETER BERTAMBAH BESARDINDING BERTAMBAH TEBALDI BAGIAN DALAM DILENGKAPI DENGAN VALVULADUCTUS THORACICUS DAN DUCTUS LYMPHATICUS DEXTER

Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsDINDING VASA LYMPHATICA

VENULAVALVULACopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsVASA LYMPHATICA BESARVASA LYMPHATICA BERDIAMETER >0,2 mmDILENGKAPI VALVULADIBEDAKAN 3 LAPISAN DINDING:TUNICA INTIMATUNICA MEDIA2 LAPISAN SEL-SEL OTOT POLOSTUNICA ADVENTITIABANYAK MENGANDUNG SERABUT KOLAGEN DAN ELASTISDUCTUS THORACICUS ET DUCTUS LYMPHATICUS DEXTER (PEMBULUH LIMFE TERBESAR)DILENGKAPI DENGAN VALVULA3 LAPISAN DINDING YANG KURANG JELASTUNICA INTIMA: ENDOTIL DAN SERABUT KOLAGEN & ELASTUNICA MEDIA : SEL OTOT POLOSTUNICA ADVENTITIA: SEL-SEL OTOT POLOS MEMANJANGCopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsVASA LYMPHATICA BESAR

DUCTUS THORACICUSDUCTUS LYMPHATICUS DEXTERVENA CAVA SUPERIORCopyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsArteriesElastic arteriesMuscular arteriesArteriolesCapillariesContinuousFenestratedSinusoidalVeinsVeins, venules

13Copyright 2008 Pearson Education, Inc., publishing as Benjamin Cummings

Vessel Structure - GeneralAll vessels same basic structure3 wall layers (or tunics)Tunica adventitia (externa) - elastic and laminar fibersTunica media thickest layerelastic fibers and smooth muscle fibersTunica interna (intima) endothelium non-stick layerbasement membraneinternal elastic laminaLumen - opening14Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsStructure of Blood VesselsComposed of three layers (tunics)Tunica intima composed of simple squamous epitheliumTunica media sheets of smooth muscleContraction vasoconstrictionRelaxation vasodilation Tunica externa composed of connective tissue LumenCentral blood-filled space of a vessel15Copyright 2008 Pearson Education, Inc., publishing as Benjamin Cummings

16Copyright 2008 Pearson Education, Inc., publishing as Benjamin Cummings

17Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsStructure of Arteries, Veins, and CapillariesFigure 19.1a

18Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsTypes of Blood VesselsArteries carry blood away from the heartCapillaries smallest blood vesselsThe site of exchange of molecules between blood and tissue fluidVeins carry blood toward the heart19Copyright 2008 Pearson Education, Inc., publishing as Benjamin Cummings

20Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsTypes of ArteriesElastic arteries the largest arteries Diameters range from 2.5 cm to 1 cmIncludes the aorta and its major branchesSometimes called conducting arteriesHigh elastin content dampens surge of blood pressureAorta, brachiocephalic, common carotid, subclavian, vertebral, pulmonary, common iliac

21Copyright 2008 Pearson Education, Inc., publishing as Benjamin Cummings

Elastic (conducting) arteriesNear heartThick wallsMore elastic fiber, less smooth muscleLose elasticity with agingVessel Structure Elastic Arteries22Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsVessel Structure - Elastic ArteriesAorta and elastic arteriesCan vasoconstrict or vasodilateLarge arteries expand, absorb pressure wave then release it with elastic recoil - Windkessel effect Help to push blood along during diastoleWith aging have less expansion and recoil

23Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsTypes of ArteriesMuscular (distributing) arteriesLie distal to elastic arteriesCapable of grater vasoconstriction and vaodilation to adjust the blood flowDiameters range from 1 cm to 0.3 mmIncludes most named arteriesTunica media is thick, More smooth muscleLess elastic fibersMany of the arteries anastomoseUnique features Internal and external elastic laminae Distribute blood to skeletal muscles & internal organsEx: external carotid, brachial, mesenteric, femoral

Figure 19.2b

24Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsFigure 19.2cTypes of ArteriesArteriolesSmallest arteriesDiameters range from 0.3 mm to 10 m Larger arterioles possess all three tunicsDiameter of arterioles controlled byLocal factors in the tissues (02 levels)Sympathetic nervous systemhormonal stimulation

25Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsArteriolesArterioles are small arteries that deliver blood to capillaries.Also have the three layers as an artery.Tunica media 1-2 layers of smooth muscle fibersA change in diameter of arterioles can significantly affect blood pressure.Through constriction and dilation, arterioles assume a key role in regulating blood flow from arteries into capillaries and in altering arterial blood pressure.26Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsVessel Structure - CapillariesAllow exchange of nutrients and wastes between blood and tissue Capillary structure - simpleBasal lamina - connective tissueEndothelial cellsStructure/function

27Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsArteriole: structureMetarterioleArterioleCapillary

Activity 3

28Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsCapillariesSmallest blood vesselsDiameter from 810 mRed blood cells pass through single fileSite-specific functions of capillariesLungs oxygen enters blood, carbon dioxide leavesSmall intestines receive digested nutrientsEndocrine glands pick up hormonesKidneys removal of nitrogenous wastes

29Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsCapillariesTempat pertukaran material nutrien antara darah dan jaringan.Tempat terjadinya mikrosirkulasi:aliran darah dari arteriole menuju venule malaui kapiler.capiller tidak berpori (continuous Capillaries) dan berpori ( fenestrated).Precappilary sphincters mengatur aliran darah melalui capillaries.Pada liver berupa sinusoid30Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsCapillariesCapillary walls are made of a single layer of endothelial cells and a basement membrane. They have no tunica media or tunica externa.Body tissues with high metabolic requirements, such as muscles, kidneys, liver and nervous system, have an extensive network of capillaries.Tissues with low metabolic requirements have fewer capillaries-tendons and ligaments.All covering and lining epithelia, cornea and lens of the eye-lack capillaries.31Copyright 2008 Pearson Education, Inc., publishing as Benjamin CummingsTypes of CapillariesTrue capillaries:emerge from arterioles and metarterioles.Continuous capillaries-found in skeletal and smooth muscle, conne