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UNIVERSITY CHICAGO LOYOLA UNIVERSITY CHICAGO Heterotopic Ossification Excision Following Hip Arthroscopy Molly A. Keegan, M.D. 3 John M. Redmond, M.D. 1,3 Asheesh Gupta, M.D. 1 Jon E. Hammarstedt, BA 1 Christine E. Stake, M.A. 1 Benjamin G. Domb, M.D. 1,2 1.American Hip Institute, 2. Hinsdale Orthopaedics Hinsdale, IL, 3. Mayo Clinic, Rochester, MN, 4. University of Illinois at Chicago

Heterotopic Ossification Excision Following Hip … Orthopaedics LOYOLA UNIVERSITYCHICAGO LOYOLA UNIVERSITYCHICAGO Heterotopic Ossification Excision Following Hip Arthroscopy Molly

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HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

LOYOLAUNIVERSITY CHICAGO

Heterotopic Ossification Excision Following Hip Arthroscopy

Molly A. Keegan, M.D.3

John M. Redmond, M.D.1,3

Asheesh Gupta, M.D.1

Jon E. Hammarstedt, BA1

Christine E. Stake, M.A.1

Benjamin G. Domb, M.D.1,2

1.American Hip Institute, 2. Hinsdale OrthopaedicsHinsdale, IL, 3. Mayo Clinic, Rochester, MN, 4. University of Illinois at Chicago

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

Disclosures – Dr. Benjamin Domb

• American Hip Institute Research support: o American Hip Instituteo Arthrex, Inc.o Mako Surgical Corp.o Brego ATIo Pacira

• Consulting:o Arthrex, Inc.o Mako Surgical Corp.o Pacira

• Stock:o Stryker

• Royalties:o Arthrex, Inc.o Orthomericao DJO Global

• AANA Learning Center Committee

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

BackgroundHeterotopic Ossification (HO)• Common after hip

arthroscopy• Incidence around 44%

for pts. not receiving prophylaxis

• Can still occur with preventative measures

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

Purpose

• The purpose of this study was to evaluate patient-reported outcome (PRO) scores for patients undergoing revision surgery for HO excision.

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

Methods• Study period: 2008 – 2014

o 2379 arthroscopic surgeries68 (3%) patients had revision surgery for HO excision

– Inclusion criteria was ossification of 1 cm, which eliminated 45 patients

– Final study group was 23 patientsTwo reviewers assessed radiographs for inclusion Retrospective chart review completedPatients with previous hip conditions were excluded

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

Patient-Reported Outcome Tools• The protocol included

pre- and post-operative administration of:o Modified Harris Hip Score

(mHHS)o Non-Arthritic Hip Score

(NAHS)o Hip Outcome Score

Activities of Daily Living (HOS-ADL)

Sport Specific Subscale

o Visual Analog Scale (VAS)o Satisfaction

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

Results - DemographicsParameter Measure

Follow-up Percentage 82.6%Average Follow-up Time 1.5 monthsGender

Male 10Female 13

Average Age 38.7 Laterality

Left 12Right 11

Primary Surgery Procedures

Procedure N=Femoral Osteoplasty 17Acetabuloplasty 16Iliopsoas Release 4Removal of Loose Body 3Trochanteric Bursectomy 2Labral Treatment

Base refixation 4Debridement 6Reconstruction 8Simple stitch 8

HO Excision Surgical Procedures

Procedure N

Femoroplasty 6

Chondroplasty 5

Acetabuloplasty 4

Iliopsoas Release 3

Osteoplasty (Peripheral) 2

Debridement of Trochanteric Bursitis 1

Iliotibial Band Release 1

Microfracture – Acetabulum 1

Labral Treatment

Base Refixation, Reconstruction & Simple Stitch 0

Debridement 13

Results

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

Conclusion• Improved outcome scores

and decreased pain in patients undergoing revision surgery for HO excision

• Few patients achieved good or excellent results (defined as >80 mHHS)

• Revision surgery for HO removal should be approached cautiously

• Further research warranted

HinsdaleOrthopaedics

LOYOLAUNIVERSITY CHICAGO

References• Beckmann, J. T., J. D. Wylie, et al. (2014). "The Effect of NSAID Prophylaxis and Operative Variables on Heterotopic Ossification After Hip

Arthroscopy." Am J Sports Med. • Bedi, A., R. M. Zbeda, et al. (2012). "The incidence of heterotopic ossification after hip arthroscopy." Am J Sports Med 40(4): 854-863. • Cohn, R. M., R. Schwarzkopf, et al. (2011). "Heterotopic ossification after total hip arthroplasty." Am J Orthop (Belle Mead NJ) 40(11):

E232-235. • Domb, B. G., C. E. Stake, et al. (2014). "Revision hip preservation surgery with hip arthroscopy: clinical outcomes." Arthroscopy 30(5):

581-587. • Kaplan, F. S., D. L. Glaser, et al. (2004). "Heterotopic ossification." J Am Acad Orthop Surg 12(2): 116-125. • Lee, E. K., S. Namdari, et al. (2013). "Clinical results of the excision of heterotopic bone around the elbow: a systematic review." J

Shoulder Elbow Surg 22(5): 716-722. • Neal, B., H. Gray, et al. (2002). "Incidence of heterotopic bone formation after major hip surgery." ANZ J Surg 72(11): 808-821. • Ong, C., M. Hall, et al. (2013). "Surgical technique: arthroscopic treatment of heterotopic ossification of the hip after prior hip

arthroscopy." Clin Orthop Relat Res 471(4): 1277-1282. • Ozturk, B. Y. and B. T. Kelly (2013). "Heterotopic ossification in portal sites following hip arthroscopy." Arch Orthop Trauma Surg 133(7):

979-984. • Randelli, F., L. Pierannunzii, et al. (2010). "Heterotopic ossifications after arthroscopic management of femoroacetabular impingement:

the role of NSAID prophylaxis." J Orthop Traumatol 11(4): 245-250. • Rath, E., H. Sherman, et al. (2013). "The incidence of heterotopic ossification in hip arthroscopy." Arthroscopy 29(3): 427-433. • Reichel, L. M., E. Salisbury, et al. (2014). "Molecular mechanisms of heterotopic ossification." J Hand Surg Am 39(3): 563-566. • Salisbury, E., E. Rodenberg, et al. (2011). "Sensory nerve induced inflammation contributes to heterotopic ossification." J Cell Biochem

112(10): 2748-2758.