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Journal of Controlled Release Vol. 169, No. 3, 2013 Contents Journal of Controlled Release 169 (2013) e1e7 PREFACE pp 163164 The Second Symposium on Innovative Polymers for Controlled Delivery, September 1114, 2012, Suzhou, China Zhiyuan Zhong , Jan Feijen pp 165170 Magnetic eld triggered drug release from polymersomes for cancer therapeutics Hugo Oliveira, Encarnación Pérez-Andrés, Julie Thevenot, Olivier Sandre, Edurne Berra , Sébastien Lecommandoux ⁎⁎ When exposed to a high frequency magnetic eld, internalized hybrid polymersomes (loaded with doxorubicin and superparamagnetic iron oxide nanoparticles) are able to trigger intracellular drug release and increase cytotoxicity. NANOMEDICINE pp 171179 Redox and pH-responsive degradable micelles for dually activated intracellular anticancer drug release Wei Chen, Ping Zhong, Fenghua Meng , Ru Cheng, Chao Deng, Jan Feijen, Zhiyuan Zhong pH and redox dual-responsive biodegradable micelles trigger drug release not only in the acidic endosomal compartments but also in the reducing cytoplasms, resulting in superior antitumor effect. Contents lists available at SciVerse ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel

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Journal of Controlled Release Vol. 169, No. 3, 2013

Contents

Journal of Controlled Release 169 (2013) e1–e7

PREFACE

pp 163–164The Second Symposium on Innovative Polymers for Controlled Delivery, September 11–14, 2012, Suzhou, ChinaZhiyuan Zhong ⁎, Jan Feijen

pp 165–170Magnetic field triggered drug release from polymersomes for cancer therapeuticsHugo Oliveira, Encarnación Pérez-Andrés, Julie Thevenot, Olivier Sandre, Edurne Berra ⁎, Sébastien Lecommandoux ⁎⁎

When exposed to a high frequency magnetic field, internalized hybrid polymersomes (loaded with doxorubicin and superparamagnetic iron oxide nanoparticles) are able totrigger intracellular drug release and increase cytotoxicity.

NANOMEDICINE

pp 171–179Redox and pH-responsive degradable micelles for dually activated intracellular anticancer drug releaseWei Chen, Ping Zhong, Fenghua Meng ⁎, Ru Cheng, Chao Deng, Jan Feijen, Zhiyuan Zhong ⁎

pH and redox dual-responsive biodegradable micelles trigger drug release not only in the acidic endosomal compartments but also in the reducing cytoplasms, resulting insuperior antitumor effect.

Contents lists available at SciVerse ScienceDirect

Journal of Controlled Release

j ourna l homepage: www.e lsev ie r.com/ locate / jconre l

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pp 180–184Environmental pH-sensitive polymeric micelles for cancer diagnosis and targeted therapyGuang Hui Gao, Yi Li, Doo Sung Lee ⁎

A facile and powerful pH-sensitive polymeric micelle was designed to encapsulate, deliver, and control release imaging markers and pharmaceutical agents for cancer diagnosisand targeted therapy.

pp 185–192Targeted co-delivery of docetaxel, cisplatin and herceptin by vitamin E TPGS-cisplatin prodrug nanoparticlesfor multimodality treatment of cancerYu Mi, Jing Zhao, Si-Shen Feng ⁎

pp 193–203Efficacious hepatoma-targeted nanomedicine self-assembled from galactopeptide and doxorubicin driven bytwo-stage physical interactionsJianxun Ding, Chunsheng Xiao, Yuce Li, Yilong Cheng, Nannan Wang, Chaoliang He, Xiuli Zhuang ⁎, Xiaojuan Zhu ⁎, Xuesi Chen ⁎

pp 204–210c(RGDfK) decorated micellar drug delivery system for intravesical instilled chemotherapy of superficial bladder cancerDanhua Zhou, Guan Zhang ⁎, Zhihua Gan ⁎

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pp 239–245Targeted biodegradable dendritic MRI contrast agent for enhanced tumor imagingMingzhou Ye, Yue Qian, Jianbin Tang ⁎, Hongjie Hu, Meihua Sui, Youqing Shen ⁎⁎

A tumor-targeting biodegradable dendritic CA with high contrast enhancement in MRI of tumor and minimal long-term retention is prepared and evaluated in vivo.

pp 220–227SPIO-PICsome: Development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection usingSPIO-loaded unilamellar polyion complex vesicles (PICsomes)Daisuke Kokuryo, Yasutaka Anraku, Akihiro Kishimura ⁎, Sayaka Tanaka, Mitsunobu R. Kano, Jeff Kershaw, Nobuhiro Nishiyama, Tsuneo Saga,Ichio Aoki ⁎⁎, Kazunori Kataoka ⁎⁎⁎Polyion complex vesicles, termed “PICsomes”, containing a SPIO contrast agent for MRI had a prolonged half-life in the bloodstream and high accumulation in early-stage tumors.

pp 228–238Multifunctional pH-sensitive superparamagnetic iron-oxide nanocomposites for targeted drug delivery and MR imagingLijuan Zhu, Dali Wang, Xuan Wei, Xinyuan Zhu ⁎, Jianqi Li ⁎⁎, Chunlai Tu, Yue Su, Jieli Wu, Bangshang Zhu, Deyue Yan ⁎⁎

A multifunctional SPIO nanocomposite system with long circulation, magnetic targeting, controlled release and MRI was successfully constructed. It is a brand new hybridmaterial for synergistic MRI diagnosis and tumor therapy.

pp 211–219Construction of block copolymers for the coordinated delivery of doxorubicin and magnetite nanocubesYong Wang, Nor Lizawati Ibrahim, Jiang Jiang, Shujun Gao, Nandanan Erathodiyil, Jackie Y. Ying ⁎

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pp 246–256Decationized crosslinked polyplexes for redox-triggered gene deliveryLuís Novo, Ethlinn V.B. van Gaal, Enrico Mastrobattista, Cornelus F. van Nostrum, Wim E. Hennink ⁎

GENE AND PROTEIN DELIVERY

pp 257–265Therapeutic targeting of chitosan–PEG–folate-complexed oncolytic adenovirus for active and systemic cancer gene therapyOh-Joon Kwon, Eunah Kang, Joung-Woo Choi, Sung Wan Kim, Chae-Ok Yun ⁎

pp 266–275Carbohydrate-interactive pDNA and siRNA gene vectors based on boronic acid functionalized poly(amido amine)sMartin Piest, Marc Ankoné, Johan F.J. Engbersen ⁎

pp 276–288DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysineZuzana Kadlecova, Yashas Rajendra, Mattia Matasci, Lucia Baldi, David L. Hacker, Florian M. Wurm, Harm-Anton Klok ⁎

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pp 289–295Surfactant free preparation of biodegradable dendritic polyglycerol nanogels by inverse nanoprecipitation forencapsulation and release of pharmaceutical biomacromoleculesDirk Steinhilber, Madeleine Witting, Xuejiao Zhang, Michael Staegemann, Florian Paulus, Wolfgang Friess, Sarah Küchler, Rainer Haag ⁎

pp 296–305Calcium depletion-mediated protease inhibition and apical-junctional-complex disassembly via an EGTA-conjugatedcarrier for oral insulin deliveryEr-Yuan Chuang, Kun-Ju Lin, Fang-Yi Su, Hsin-Lung Chen, Barnali Maiti, Yi-Cheng Ho, Tzu-Chen Yen, Nilendu Panda, Hsing-Wen Sung ⁎

pp 306–312Protective effects of protein transduction domain-metallothionein fusion proteins against hypoxia- and oxidativestress-induced apoptosis in an ischemia/reperfusion rat modelKwang Suk Lim, Min-Ji Cha, Jang Kyoung Kim, Eun Jeong Park, Ji-Won Chae, Taiyoun Rhim, Ki-Chul Hwang, Yong-Hee Kim ⁎

Interstitial fibrosis (upper panel) and myocardial apoptosis (bottom panel) in ischemia/reperfusion rat model.

pp 313–320Multifunctional conducting fibres with electrically controlled release of ciprofloxacinDorna Esrafilzadeh, Joselito M. Razal, Simon E. Moulton, Elise M. Stewart, Gordon G. Wallace ⁎

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pp 321–328Polyalkylcyanoacrylates as in situ formed diffusion barriers in multimaterial drug carriersChristian Wischke, Cornelius Schneider, Axel T. Neffe, Andreas Lendlein ⁎In situ polymerization of alkylcyanoacrylate formingmembranes on alginate hydrogels create diffusion barriers to sustain drug release. The conceptmay be applied to various hydrogel types andshapes.

pp 329–335Simply mixing with poly(ethylene glycol) enhances the fraction of the active chemical form of antitumor drugsof camptothecin familyTianyuan Ci, Ting Li, Guangtao Chang, Lin Yu, Jiandong Ding ⁎

pp 336–340Cell sheet transplantation for heart tissue repairKatsuhisa Matsuura, Yuji Haraguchi, Tatsuya Shimizu, Teruo Okano ⁎Current cell sheet transplantation repairs the injured heart via mainly paracrine mechanisms.

pp 341–347Polymeric “smart” coatings to prevent foreign body response to implantable biosensorsYan Wang, Fotios Papadimitrakopoulos, Diane J. Burgess ⁎

BIOMATERIALS AND TISSUE ENGINEERING

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⁎,⁎⁎,⁎⁎⁎ Corresponding author

Cited in: BIOSIS/Biological Abstracts; CAB Abstracts; Chemical Abstracts Services; Current Contents (Life Sciences); EMBASE/Excerpta Medica; International Pharmaceutical Abstracts; PUBMED/MEDLINE/Index Medicus; Polymer Contents; ScienceCitation Index. Also covered in the abstract and citation database SciVerse SCOPUS®. Full text available in SciVerse ScienceDirect®

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