6
PEOPLE Genetic code work leads to 1968 Nobel Prize Medicine prize goes to Marshall W. Nirenberg, Har Gobind Khorana, and Robert W. Holley for independent work R. W. Holley H. G. Khorana Each of the three U.S. chemists who have won the 1968 Nobel Prize for Medicine and Physiology (C&EN, Oct. 21, page 18) worked independently. But it was their combined work that led to the understanding of much of the mysterious way information is coded into the nucleic acids and used to direct the incorporation of specific amino acids into proteins. Their re- search represents a major contribution toward scientists' understanding on a molecular basis of how the chemicals of the cell nucleus carry the hereditary message from one generation to the next. Jointly sharing the $70,000 cash prize awarded by the medical faculty of the Royal Caroline Institute in Stockholm, Sweden, are Dr. Marshall W. Nirenberg, 41, of National Insti- tutes of Health, Dr. Har Gobind Khor- ana, 46, of University of Wisconsin, and Dr. Robert W. Holley, 46, formerly of Cornell University and now at Salk Institute for Biological Studies in San Diego, Calif. Dr. Nirenberg prepared a cell-free system which synthesized protein in the presence of amino acids and en- ergy sources (adenosine triphosphate) from the bacterium, Escherichia coli. Then he showed for the first time that messenger ribonucleic acid (RNA) is required for cell-free pro- tein synthesis. In 1961 Dr. Nirenberg and Dr. J. H. Matthei showed that the synthetic RNA's, polyuridine and polycytidine, are templates for the incorporation into protein of phenylalanine and pro- line, respectively. Further experi- ments with other synthetic RNA's con- taining various proportions of purines and pyrimidines revealed codes for nearly all the known amino acids nor- mally present in protein. More recently Dr. Nirenberg and his coworkers found a general method of great simplicity for determining the base sequence of codons. With this they showed directly that since tri- but not dinucleotides serve as tem- plates in this system, a triple code ex- ists. Dr. Nirenberg was born in 1927 in New York City. He received his B.S. and M.S. from University of Florida, Gainesville, and his Ph.D. in biochem- istry in 1957 from University of Michi- gan, Ann Arbor, where he did re- search on a permease for hexose trans- port under Dr. J. F. Hogg. He then joined NIH as a postdoctoral fellow and in 1962 he became head of the section of biochemical genetics of Na- tional Heart Institute. In 1966, he was named chief of NHI's laboratory of biochemical genetics. Dr. Khorana and his coworkers at Wisconsin's Institute for Enzyme Re- search made a major contribution to- ward solving the genetic code by synthesizing short, biologically active chains of deoxyribonucleic acid (DNA) with known sequences of bases. Two general synthetic ap- proaches were developed. One in- volved the stepwise addition of a mononucleotide to the 3-hydroxyl end of a growing oligonucleotide chain. Either dicyclohexylcarbodi- imide (DCC) or mesitylenesulfonyl chloride was used as the condensing NOBEL LAUREATE. 1968 winner Dr. Marshall W. Nirenberg and Mrs. Niren- berg field questions from the press agent. The other approach involved the polymerization of dinucleotides in the presence of DCC. These small DNA molecules could be treated with the enzyme DNA pol- ymerase to make long, double- stranded DNA-like molecules having the same known base sequence but now repeated over and over. The long compound could, in turn, be acted upon by another enzyme (RNA polymerase) to make equally long RNA molecules with the same, though complementary, repeating se- quence. The work of Dr. Khorana and his associates gave direct proof that the genetic code is a nonoverlap- ping one, read three bases at a time, in triplets. 66 C&EN OCT. :?, 1968

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Page 1: Genetic code work leads to 1968 Nobel Prize

PEOPLE

Genetic code work leads to 1968 Nobel Prize Medicine prize goes to Marshall W. Nirenberg, Har Gobind Khorana, and Robert W. Holley for independent work

R. W. Holley

H. G. Khorana

Each of the three U.S. chemists who have won the 1968 Nobel Prize for Medicine and Physiology (C&EN, Oct. 21, page 18) worked independently. But it was their combined work that led to the understanding of much of the mysterious way information is coded into the nucleic acids and used to direct the incorporation of specific amino acids into proteins. Their re­search represents a major contribution toward scientists' understanding on a molecular basis of how the chemicals of the cell nucleus carry the hereditary message from one generation to the next.

Jointly sharing the $70,000 cash prize awarded by the medical faculty of the Royal Caroline Institute in Stockholm, Sweden, are Dr. Marshall W. Nirenberg, 41, of National Insti­tutes of Health, Dr. Har Gobind Khor­ana, 46, of University of Wisconsin, and Dr. Robert W. Holley, 46, formerly of Cornell University and now at Salk Institute for Biological Studies in San Diego, Calif.

Dr. Nirenberg prepared a cell-free system which synthesized protein in the presence of amino acids and en­ergy sources (adenosine triphosphate) from the bacterium, Escherichia coli. Then he showed for the first time that messenger ribonucleic acid (RNA) is required for cell-free pro­tein synthesis.

In 1961 Dr. Nirenberg and Dr. J. H. Matthei showed that the synthetic RNA's, polyuridine and polycytidine, are templates for the incorporation into protein of phenylalanine and pro­line, respectively. Further experi­ments with other synthetic RNA's con­taining various proportions of purines and pyrimidines revealed codes for nearly all the known amino acids nor­mally present in protein.

More recently Dr. Nirenberg and his coworkers found a general method of great simplicity for determining the base sequence of codons. With this they showed directly that since tri­but not dinucleotides serve as tem­plates in this system, a triple code ex­ists.

Dr. Nirenberg was born in 1927 in New York City. He received his B.S. and M.S. from University of Florida, Gainesville, and his Ph.D. in biochem­istry in 1957 from University of Michi­gan, Ann Arbor, where he did re­search on a permease for hexose trans­port under Dr. J. F. Hogg. He then joined NIH as a postdoctoral fellow

and in 1962 he became head of the section of biochemical genetics of Na­tional Heart Institute. In 1966, he was named chief of NHI's laboratory of biochemical genetics.

Dr. Khorana and his coworkers at Wisconsin's Institute for Enzyme Re­search made a major contribution to­ward solving the genetic code by synthesizing short, biologically active chains of deoxyribonucleic acid (DNA) with known sequences of bases. Two general synthetic ap­proaches were developed. One in­volved the stepwise addition of a mononucleotide to the 3-hydroxyl end of a growing oligonucleotide chain. Either dicyclohexylcarbodi-imide (DCC) or mesitylenesulfonyl chloride was used as the condensing

NOBEL LAUREATE. 1968 winner Dr. Marshall W. Nirenberg and Mrs. Niren­berg field questions from the press

agent. The other approach involved the polymerization of dinucleotides in the presence of DCC.

These small DNA molecules could be treated with the enzyme DNA pol­ymerase to make long, double-stranded DNA-like molecules having the same known base sequence but now repeated over and over.

The long compound could, in turn, be acted upon by another enzyme (RNA polymerase) to make equally long RNA molecules with the same, though complementary, repeating se­quence. The work of Dr. Khorana and his associates gave direct proof that the genetic code is a nonoverlap-ping one, read three bases at a time, in triplets.

66 C&EN OCT. :?, 1968

Page 2: Genetic code work leads to 1968 Nobel Prize

Born in Raipur, India, Dr. Khorana received a B.Sc. in 1943 and M.Sc. in 1945 from Punjab University, India, and a Ph.D. in 1948 from University of Liverpool, England. After post­doctoral fellowships at the Federal Institute of Technology, Zurich, Swit­zerland, and University of Cambridge, England, he was head of the organic chemistry group of the British Com­monwealth Research Council in Van­couver, B.C., from 1952 to 1960, the last two years of which he spent as a visiting professor at Rockefeller Insti­tute in New York City. He went to University of Wisconsin in 1960 and in 1964 was given the Conrad A. Elvehjem Professorship in the Lite Sciences.

Dr. Holley and his coworkers at USDA and the biochemistry depart­ment at Cornell in Ithaca, N.Y., were the first to elucidate the nucleotide sequence of an amino acid-specific transfer RNA—in this instance, ala­nine transfer RNA (ala-tRNA). Im­portant work paving the way to this accomplishment was the Cornell group's isolation by countercurrent distribution of the yeast alanine, ty­rosine, and valine t-RNA's sufficiently pure for structural studies. The Cornell group subjected the ala-tRNA to enzymic digestion and separated 16 smaller fragments (oligonucleo­tides) obtained using solution chro­matography. Each of the separated fragments was hydrolyzed with al­kali and the component mononucleo­tides were identified by chromato­graphic, electrophoretic, and spectral properties. The overall process re­quired nearly two and a half years of work by Dr. Holley and his group.

Dr. Holley received his B.A. in chemistry at University of Illinois, Urbana, in 1942. He obtained his Ph.D. in organic chemistry in 1947 from Cornell where he worked with Dr. Alfred T. Blomquist on reactions of ketene and synthesis of large-ring compounds. After spending a year at State College of Washington, Pullman, he returned to Cornell in 1948, where he was associated with the New York State Experimental Station and the U.S. Plant, Soil, and Nutritional Lab­oratory. He was named professor of biochemistry at Cornell in 1964. Last month, he was appointed a resident fellow at the Salk Institute.

Earlier this month, Columbia Uni­versity awarded Dr. Khorana and Dr. Nirenberg jointly the 1968 Louisa Gross Horwitz Prize of $25,000 for outstanding research in biochemistry. Also this month, Dr. Nirenberg, who is a C&EN editorial advisory board mem­ber, was awarded the 1968 Franklin Medal by Franklin Institute in Phila­delphia in recognition of his key role in solving the genetic code.

Five honored at ACS Northeast meeting McConnell, Kamerling, Root, Kistiakowsky, and Hammond cited at Boston conclave

Near the end of the first ACS North­east Regional Meeting in Boston, chemists gathered for a special awards luncheon honoring five recip­ients. Dr. David W. Stewart, past chairman of the Rochester Section, announced the first: the Harrison Howe Award for "achievement in chemistry" to Dr. Harden M. Mc­Connell, professor of chemistry at Stanford. Presentation will be in Rochester, N.Y., on Nov. 12.

Next, Dr. Avery A. Ashdown, emer­itus associate professor at MIT, pre­sented the James Flack Norris Award for Outstanding Achievement in the Teaching of Chemistry to Dr. Samuel E. Kamerling and Dr. William C. Root, professors of chemistry at Bowdoin College.

The Theodore William Richards Medal for conspicuous achievement in chemistry was presented to Dr. George B. Kistiakowsky, professor of chemistry at Harvard, by Dr. Arno H. A. Heyn, chairman of the North­eastern Section, and the James Flack Norris Award for Outstanding Con­tributions to Physical Organic Chem­istry was presented by ACS President Robert W. Cairns to Dr. George S. Hammond, professor of chemistry at Caltech.

Dr. Hammond capped the cere­mony with an award address on The Future of Chemical Science (C&EN, Oct. 21, page 19).

Dr. Louis F. Fieser (right) congratulates Dr. Samuel E. Kamerling (left) and Dr. William C. Root

ACS President Cairns and Dr. George S. Hammond

Dr. Arno A. Heyn and Dr. George B. Kistiakowsky

OCT. 28, 1968 C&EN 67

Page 3: Genetic code work leads to 1968 Nobel Prize

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Benzyl Mercaptan p-Bromothiophenol

p-Chlorobenzyl Mercaptan p-Chlorothiophenol

2-Diethylaminoethanethiol Hydrochloride Iso-octyl Thioglycolate

2-Mercaptoethylamine Hydrochloride 3-Mercaptopropionic Acid Ootadecyl Thioglycolate

Thioacetic Acid (thiolacetic acid) Thiobenzoic Acid

1-Thioglycerol Thioglycolic Acid Thiolactic Acid Thiomalic Acid

Thiosalicylic Acid

P0LYTHIOLS-POLYMERCAPTANS-R-(SH)n b,b' dimercapto diethyl ether

Dithiolterephthalic Acid Glycol Dimercaptoacetate

Pentaerythritol Tetra (3-Mercaptopropionate)

DITHIO COMPOUNDS-DISULFIDES-R-S-S-R Dithiodiglycolic Acid

Dithiodipropionic Acid

THIOETHERS-THIOCOMPOUNDS-SULFIDES-R-S-R p-Chlorothioanisole

Distearyl Thiodipropionate Dilauryl Thiodipropionate

Thiodiglycolic Acid Thiodipropionic Acid

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Robert W. Cairns will receive Perkin Medal A tremor of surprise ran through the crowd at the recent SCI dinner at the New York Hilton when Dr. Robert W. Cairns was announced as Perkin Med­

alist for 1969. But it was the timing of the announcement by Society of Chem­ical Industry chairman Jesse Werner, not the selection of Dr. Cairns, which caused the stir. Recent practice has been that the name of the Perkin Medal winner is not revealed until several weeks after the fete in honor of the recipient of the Chemical Industry Medal, given by SCI (C&EN, Oct. 7, page 110).

The Perkin award was established in 1906, and is, SCI says, the highest honor given for outstanding work in applied chemistry in the U.S. Dr. Cairns, vice president and member of the board of directors of Hercules, Inc., will receive the award at the annual Perkin Medal Dinner of the American Section, Feb. 20, 1969.

Dr. Cairns was selected, as are all Perkin Medalists, by a jury of award composed of representatives of SCI's American Section, ACS, American In­stitute of Chemical Engineers, Electro­chemical Society, Société de Chimie Industrielle^ American Section, and American Institute of Chemists.

A native of Oberlin, Ohio, Dr. Cairns attended the University of Cali­fornia, received his B.A. from Oberlin College (1930), and his doctorate from Johns Hopkins (1932). He also participated in the advanced manage­ment program at Harvard Business School. He joined Hercules in 1934, was appointed director of research in 1955, elected to the board in 1959, and became a vice president concen­trating on research and development in 1966.

Dr. Cairns served as Deputy Assist­

ant Secretary of Defense for R&D under the late Donald A. Quarles and is currently a member of the Defense Science Board and chairman of the National Academy's committee on sci­entific and technical communication. He has served as president of Indus­trial Research Institute and is now completing his term as ACS President.

INDUSTRY

Robert E. Bernert named director of engineering and development at Hex Industries, Westport, Mass.

Pal Emil Borondy and Ardis Marie Savory appointed biochemists at Parke-Davis, Ann Arbor. Rosalind Reiser named information specialist.

Dr. Robert A. Bra un joins Xerox Corp. as group leader in organic and poly­meric materials development, Webster, N.Y.

Charles H. Brodeur promoted to se­nior research chemical engineer at Texaco research center, Beacon, N.Y. Dr. David McCoy promoted to senior chemist.

T. E. Brown appointed manager of U.S. area inorganic and solvents prod­uct department at Dow Chemical. Succeeds J. Ernest Mitchell, Jr., now director of functional materials in cor­porate product department. William J. Rave named director of fabricated products.

William R. Cake named director of growth planning at Sherwin-Williams, Cleveland. Dr. Robert M. Vance suc­ceeds him as director of research in colors and chemicals.

New on staff of Kodak research labs, Rochester, NY.: Dr. John Cholette, Dr. Jose Fernandez, Dr. Harry Hoyen, and Dr. Peter Marr, senior chemists; Eugene Trabka, research associate; and Victor Mylroie and Richard Graves, chemists.

John Corinth named assistant general manager of Witco Chemical's Witfield subsidiary, Carson, Calif.

Bernard M. Costello, v.p. of Interna­tional B. F. Goodrich Co., retires after 42 years with the company. Dr. Pa­tricia M. Dreyfuss named a senior re­search chemist on the staff of B. F. Goodrich research center, Brecksville, Ohio.

Louis A. Costello promoted to research chemist in applications section at Wa­ters Associates, Framingham, Mass.

Dr. James Fair, manager of engineer­ing technology at Monsanto; Dr. M. F.

68 C&EN OCT. 28, 1968

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Page 4: Genetic code work leads to 1968 Nobel Prize

Gautreaux, Jr., general R&D manager at Ethyl Corp.; Harold R. Sheely, senior process supervisor at Badger Co.; and Claude P. Talley, group leader at Texaco, receive the Personal Achievement Awards in Chemical En­gineering from Chemical Engineering.

Walter A. Fallon, manager of film emul­sion and plate manufacturing division of Eastman Kodak, has been named by the Society of Motion Picture and Television Engineers to receive the Herbert T. Kalmus Gold Medal Award for 1968. The award recognizes out­standing contributions in the develop­ment of color films, processes, tech­niques, or equipment useful in making color motion pictures.

John M. Ferrara promoted to techni­cal manager of metal industries lab at Nalco Chemical, Chicago. Rudolph P. Loher promoted to group leader. Michael J. Jones joins midwest dis­trict as sales representative. Carl E. Johnson appointed research associate at the company's clearing research center.

Kerien Fitzpatrick joins Chemplex Co., Clinton, Iowa, as superintendent of maintenance and engineering.

Larry Fluer joins Matheson Gas Prod­ucts as assistant branch plant manager, Newark, Calif.

Ronald L. Frantz, Richard A. Nie­mann, John B. Moriarty, and Dr. Graham Swift join Spring House, Pa., research labs of Rohm and Haas. Leonard A. Sitver transfers from Phila­delphia to Spring House. David J. Van Horn named lab manager at the Bristol, Pa., plant. Ronald D. Neu-feld joins as air and water conserva­tion engineer.

Dr. John P. Frawley, chief toxicologist for Hercules, Inc., has received the Lea Hitchner Service Award of Na­tional Agricultural Chemicals Associa­tion for his outstanding contribution to the agricultural chemicals industry.

William L. Galligan appointed research director at Frank Lumber Co., Inc., Vancouver, Wash.

Douglas B. Gehrman joins Enjay Chemical's Baytown, Tex., plant as senior engineer. Marlyn A. Doppel-hammer joins as analyst in coordina­tion department and Melvin L. Am-buehl as a chemical engineer in technical division.

Dr. Norman W. Gilman and Dr. Arnold A. Liebman appointed senior chemists at Hoffmann-La Roche, Inc., Nutley, N.J.

Philip Gisser joins Warner, Bicking & Fen wick, Inc., New York advertising agency, as partner and executive v.p.

Richard J. Goertz appointed v.p. for marketing at industrial chemicals divi­sion, Mobil Chemical, Richmond, Va.

Dr. Robin N. Greene joins research staff of Du Pont's elastomer chemicals department, Wilmington.

C. R. Grimme returns from a two-year assignment in Europe to Westinghouse Electric, Sunnyvale, Calif.

Dr. Joyce F. Grunwell joins Wm. S. Merrell Co., Cincinnati, as organic re­search chemist.

Dr. Willard C. Hamilton, Dr. Edward Sie, and Dr. Brian Sweetman join re­search staff of Gillette Research Insti­tute, Rockville, Md.

Richard J. Haughwout named product manager, cellulosics by Celanese Plas­tics Co., Newark, N.J. Mrs. Maryann Keller named marketing research ana­lyst.

Dr. George F. Huff elected worldwide coordinator of chemicals for Gulf Oil, Pittsburgh. Succeeds Frank L. Pyle, now executive v.p. of the company for Eastern Hemisphere, a newly created position with headquarters in London.

Joseph B. Hyman has been appointed consultant and representative in the U.S. for Resistol, a Mexican company. His office is in Plainfield, N.J. He has been executive assistant to the senior v.p. at Ashland Chemical Co. and was formerly executive v.p. and technical director in charge of R&D at Catalin Corp.

Ralph V. Johnson named manager of technical services at Dixie Chemical Co., Houston.

Herbert J. Kandel named general man­ager of American Chemical Corp., Carson, Calif.

Andreas A. Kapsalis named senior sci­entist at Baxter Laboratories, Inc., Morton Grove, 111.

Richard M. Kerr named manager of Lynchburg, Va., plant of E. F. Houghton & Co.

William T. Kiessling named industry manager-fabrics at Ruco division of Hooker Chemical, Hicksville, N.Y.

Charles E. Kirby joins technical divi­sion of Humble Oil & Refining's Bay-town refinery as an engineer. Dr. John I. Elsey joins as senior engineer.

Stouffer Prize goes to Skeggs and Bumpus Dr. Leonard T. Skeggs and Dr. F. Merlin Bumpus of Cleveland Clinic Foundation share, along with two Eu­ropean scientists, the $50,000 Stouffer

Skeggs Bumpus

Prize for 1968. They were cited for studies contributing to greater under­standing of the control of blood pres­sure.

Dr. Skeggs is professor of biochem­istry in the department of pathology at Case Western Reserve, and chief of the biochemistry section and codirec-tor of the hypertension laboratory, Veterans Administration Hospital, Cleveland.

Dr. Bumpus is chairman and scien­tific director of the division of research at Cleveland Clinic Foundation.

The other two who shared the prize are Dr. William S. Peart of St. Mary's Hospital, London, and Dr. Robert Schwyzer of Swiss Federal Institute of Technology, Zurich.

The Stouffer Prize is awarded by the council for high blood pressure re­search of the American Heart Asso­ciation.

Peter D. Klugherz joins Rohm and Haas, Philadelphia, as a chemist. Eddy A. Hazbun joins as engineer.

Paul A. Koons named director of mar­keting for chemical division of Thiokol Chemical, Trenton, N.J.

John F. Kroeger named general man­ager for wholesale marketing at Shell Oil.

Dick Kruger elected v.p. of Pace Co. Consultants & Engineers, to head en­vironmental sciences.

Dr. Karl Laden and Dr. Robert Spitzer have been given the 1967 IFF Award of $1000 for their paper, Identifica­tion of a Natural Moisturizing Agent in Skin. Funded by International Flavors & Fragrances, Inc., it is pre­sented annually by the Society of Cos­metic Chemists. Dr. Laden is man­ager of biomedical sciences division at Gillette Research Institute and Dr. Spitzer is assistant professor at Chi­cago Medical School.

OCT. 28, 1968 C&EN 69

Page 5: Genetic code work leads to 1968 Nobel Prize

EDUCATION

Winnacker honored by SCI's American Section Dr. Hillary Robinette, Jr., president of the American Section of Société de Chimie Industrielle, congratulates Dr. Karl Winnacker (center), president of Farbwerke Hoechst, A.G., recipient of the Palladium Medal. Inspector General Georges Fleury of the French Atomic Energy Commission, who is president of SCI, is on the right. Dr. Winnacker was honored by the American Section for outstanding contributions to the chemical industry.

Walter Lang named chemical sales product engineer at B. F. Goodrich Chemical Co., Cleveland. Thomas E. Kormanik appointed senior sales rep­resentative for special-purpose elas­tomers in South Central states. Kevin P. Mayer named to a similar position in Chicago.

Richard M. Leader promoted to direc­tor of special products division of Phillips Petroleum's chemical depart­ment, Bartlesville, Okla.

E. W. Long, Jr., joins Mares & Groppe, petrochemical consultants, Houston, Tex.

Earl W. Malcolm named research asso­ciate in product development at C. H. Dexter division of Dexter Corp., Wind­sor Locks, Conn.

Juan Marti nez, Jr., becomes chief chemist at Victorville, Calif., plant of Southwestern Portland Cement Co. He succeeds Lloyd R. Indermuehle, retiring after more than 40 years with the company.

David E. McGrain promoted to plant manager of organics division clearing, Chicago, for Witco Chemical. John G. Schoepf, Jr., named manager of Perth Amboy plant.

Theodore T. Miller elected to board of directors of Lowell Industries, Inc., Boston. He is a consultant in chemi­cals, plastics, and synthetic fibers.

Robert T. Murphy named director of agricultural analytical chemistry at Geigy Chemical Corp., Ardsley, N.Y.

L. T. O'Brien named vinyl industry manager-rigids of Nuodex division at Tenneco Chemicals, Piscataway, N.J.

Clifford E. Oman appointed director of production for U.S. Industrial Chemi­cals.

John J. Pardue joins Apollo Chemical Corp. as technical representative in southern New Jersey, Clifton.

Dr. Heinz G. Pfeiffer named manager of educational technology program at GE R&D center, Schenectady. Dr. Manuel Aven appointed manager of the luminescence branch.

GOVERNMENT

Dr. Ronald E. Kagarise has been named su­perintendent of chemistry division at Naval Re­search Labo­ratory, Washing­ton, D.C. He has been program di­rector for struc­

tural chemistry at National Science Foundation.

Dr. Wayne W. Meinke, chief of Na­tional Bureau of Standards' office of standard reference materials and of the bureau's analytical chemistry divi­sion, has been given the first George von Hevesy Award presented by the Journal of Radioanalytical Chemistry. He was honored for his contributions to radioanalytical chemistry.

Dr. Gerald R. Bakker becomes chair­man of chemistry department at Earl-ham College, Richmond, Ind. He re­places Dr. Wilmer Stratton. Dr. Ricardo Ferreira, Dr. Warren Smith, and Dr. Charles Springer join chemis­try department staff.

Dr. John Bardeen, professor of physics and electrical engineering at Univer­sity of Illinois, receives the Albert A. Michelson-Edward W. Morley Award of Case Western Reserve University. He was cited for his work on develop­ing an explanation for superconduc­tivity. The award consists of $5000 and a plaque.

Kwang-Chu Chao joins Purdue faculty as professor of chemical engineering.

Dr. Robert T. Conley, who has been chairman of the chemistry de­partment at Wright State Uni­versity, Dayton, Ohio, has been promoted to dean of science and en-

Con ley gineering. He will continue as chemistry department chairman on an acting basis. Dr. James J. Kane has been promoted to associate professor of chemistry.

Dr. Wayne B. Counts named head of chemistry department at Lincoln Me­morial University, Harrogate, Tenn. He replaces Dr. John H. Mote, named academic dean of the university. Mary Chao Lu joins the chemistry de­partment as professor.

Dr. William Prins named professor of chemistry at Syracuse University. From Delft Institute of Technology.

Dr. Newton Ressler named assistant director of laboratories at University of Illinois Hospitals.

Dr. Michael A. Sancho joins depart­ment of chemistry at Ottawa Univer­sity, Ottawa, Kan., as assistant profes­sor.

Dr. Earle Scott promoted to professor and Dr. James Beatty to associate pro­fessor of chemistry at Ripon College, Ripon, Wis. Dr. Richard Scamehorn joins as assistant professor and Thomas Oyster as instructor in chemistry and computer science.

James J. Shipman, v.p. of Kimberly Clark Corp., delivers the annual Chemical Honor Society Lecture at Worcester Polytechnic Institute, on Educational Responsibilities of Indus­try.

70 C&EN OCT. 28, 1968

Page 6: Genetic code work leads to 1968 Nobel Prize

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high temperature Esterification, alkylation, oxyalkytetion, polymerization Complete vapor and liquid chemical waste recov­

ery systems for sale or long term lease AAA-l Rated Company

lf^% Write for Bulletin #767

fVHercuru :%:#:'CHEMICAL CORP. I

P.O. Box 162, Old Bridge, N.J. 08857 (201) 727-3100

YOUR ANNOUNCEMENT in Equipment Mart can carry YOUR MESSAGE to the readers of the leading publication in the chemical process industries.

CHEMICAL & ENGINEERING NEWS

Advertising Office 430 Park Avenue New York, N. Y. 10022

DIRECTORY SECTION

This section includes: CHEM­ICALS EXCHANGE—Chemicals, Resins, Gums, Oils, Waxes, Pig­ments, etc: EQUIPMENT MART —New and Used Equipment, In­struments; Facilities for Plant and Laboratory; TECHNICAL SERV­ICES—Consultants; Engineering, Testing, Professional Services.

Advertising Rates: Space rate is $74 per inch. Lower rates available on contract basis. An "inch" ad­vertisement measures Vs" deep on one column. Additional space in even lineal inch units. Maximum space—4" per Directory per issue. Set ads due 21 days in advance of publication; plated ads, 17 days.

TECHNICAL SERVICES

ANALYTICAL SERVICES 3 MASS SPECTROMETRY g Organics - Gas Analysis - Ν'5, Ο1·, Η2, He3 Isotopes g COMBINED GC-MS g THERMAL ANALYSIS-DTA-TGA-DSC g

WEST COAST 3 TECHNICAL SERVICE 2 1049 S. San Gabriel Blvd. S San Gabriel, California 91776 3 (213) 287-0926

CLARK MICROANALYTICAL LABORATORY

C H , N , S, H a l o s e n , F luor ine , O x y s e n , A l k o x y , A l k i m i d e , A c e t y l , Terminal M e t h y l , etc. by spec ia l ­ists in organic microchemical analysis.

H o w a r d S. C l a r k , D i rec tor P . O . Box 6 9 , Phone: 2 1 7 - 3 6 7 - 8 4 0 6 , Urbana, I I I .

CHILDERS MICROANALYTICAL LABORATORIES

Organic Microanalysis Specializing in Thermally Stable Compounds

Results within three days P.O. Box 517, M i l f o r d , N. J . 08848

Phone 215-847-5261

tooUA fePECTRO-CHEMICAL LABORATORY

Division of Ccors Porcelain Company

For Analytical Services Send Inquiries To:

P.O. BOX 5865 DENVER, COLORADO 80217

SCHWARZKOPF MICROANALYTICAL LABORATORY 56-19 37th Ave . , Woodside, N.Y. 11377

Telephone: Code 212, HAvemeyer 9-6248; 9-6223 ELEMENTAL ANALYSES

ORGANICS, INORGANICS, ORGANO METALLICS METALS BY ATOMIC ABSORPTION

MOLECULAR WEIGHT, FUNCTIONAL GROUPS Trace Analyses Research

Routine analyses within 5 days

OCT. 28, 1968 C & E N 71

STEEL TANKS

Cifl rfti

200 Gal. Aluminum Tank

CAT. # 1 0

WATER ANALYSIS PROCEDURES

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