19
Rungsun Chaisevikul, M.D. Charcrin Nabangchang, M.D. Epilepsy Highlight 2009

Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

  • Upload
    others

  • View
    4

  • Download
    0

Embed Size (px)

Citation preview

Page 1: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Rungsun Chaisevikul, M.D.

Charcrin Nabangchang, M.D.

Epilepsy Highlight 2009

Page 2: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Epilepsy Highlight2009

Pharmacogenomics/ Pharmacogenetics

Pregnancy & epilepsy

Novel RX:Carisbamate, Lacosamide, Retigabine,

Rafinamide, Brivaracetam, Talampanel, Neuropace

New drug in Thailand: Fosphenytoin,

Levetiracetam syrup

Upcoming drug to Thailand:I.V. Levetiracetam,

Zonisamide

New syndrome: new epileptic syndrome

Page 3: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Epilepsy Highlight2009

New therapy: DBS, Neuropace

Page 4: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 5: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 6: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Picture from Epilepsia 2009;50:1-23

Page 7: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 8: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 9: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 10: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 11: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 12: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Epilepsia 2009;suppl5:58-61

Page 13: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 14: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 15: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Epilepsia 2008:49;1504

Page 16: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified
Page 17: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

Picture from Epilepsia 2009;50:694

Page 18: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified

0

20

40

60

80

Control Hypoxia Hypoxia/TPM

Hypoxia-Induced Long-Term

Susceptibility

to Neuronal Injury

Koh S, Jensen FE. Ann Neurol 50:366, 2001

DN

A F

rag

men

tati

on

Den

sit

y

P<0.01

Page 19: Epilepsy Highlight 2009 2009 for web.pdf · Epilepsy Highlight2009 ... Antiepileptic drugs during pregnancy: What is known and which AEDs seem to be safest? Page B. Pennell ... Modified