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Aims and Scope The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. Our aim is to publish articles of high scientific quality which describe the mechanical properties of these materials and elucidate the underlying mechanisms which determine these properties. Reports of fundamental scientific investigations of a theoretical or experimental nature are welcome, as are articles concerned with the development of materials for medical devices. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, short communications (e.g. case studies), letters to the editor, opinion pieces and, by invitation, review articles and tutorials. The journal offers the opportunity for ample space to develop an argument in full and the services of referees with expertise in mechanical behaviour and an understanding of the special nature of biomedical materials. Examples of relevant subjects include: • Stress/strain/time relationships for biological materials • Fracture mechanics of hard tissues • Tribological properties of joint materials and their replacements, including coatings • Mechanical characterisation of tissue engineering materials and scaffolds • The mechanical behaviour of cells, including adhesion • Response of cells to mechanical stimuli • Mechanical properties of biological molecules such as DNA • Long-term fatigue, creep and wear properties of biomaterials used in implants • The behaviour of the human body under impact loading • Mechanical performance all natural materials, including those from plants and animals • New techniques for the measurement of mechanical properties in biomedical materials, in both laboratory and clinical practice • Computer simulations of material behaviour • Clinical case histories related to material performance The journal publishes papers from the proceedings of the International Conference on the Mechanics of Biomaterials and Tissues; special issues devoted to particular subjects or events are also published from time to time. Editor in Chief - David Taylor, Trinity College, Dublin, Ireland, Email: [email protected] Associate Editors F. O’Brien, Royal College of Surgeons, Ireland C. Simms, Trinity College, Ireland P. Vallittu, University of Turku, Finland Editorial Board T. Adachi, Kyoto University, Japan O. Akkus, Purdue University, USA G. Bao, Georgia Institute of Technology, USA M. Buehler, Massachusetts Institute of Technology, USA J. Currey, University of York, UK S. Evans, Cardiff University, UK R. Geesink, Universiteit Maastricht, Netherlands A. Gefen, Tel Aviv University, Israel K. Hayashi, Okayama University of Science, Japan R. Ker, University of Leeds, UK J. Kruzic, Oregon State University, USA C. Lee, Royal College of Surgeons, Ireland R.L. Mauck, University of Pennsylvania, USA R. McMeeking, University of California, USA Marc A. Meyers, University of California, San Diego, USA M. Niinomi, Tohoku University, Japan C. Oomens, Eindhoven University of Technology, The Netherlands M. Oyen, University of Cambridge, UK P. Prendergast, Trinity College, Ireland R. Ritchie, University of California at Berkeley, USA R. Roeder, University of Notre Dame, USA H. Screen, Queen Mary, University of London, UK S. Suresh, Massachusetts Institute of Technology, USA M. Swain, University of Sydney, Australia S.H. Teoh, Division of Bio Engineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore T. Tomsia, University of California at Berkeley, USA D. Vashishth, Rensselaer Polytechnic Institute, USA A. Wennerberg, University of Gothenburg, Sweden P. Zioupos, Cranfield University, UK Printed in the Netherlands

Editorial board/Aims and Scope

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Aims and Scope

The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. Our aim is to publish articles of high sci entifi c quality which describe the mechanical properties of these materials and elucidate the underlying mechanisms which determine these properties. Reports of fundamental scientifi c investigations of a theoretical or experimental nature are welcome, as are articles concerned with the development of materials for medical devices. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, short communications (e.g. case studies), letters to the editor, opinion pieces and, by invitation, review articles and tutorials.

The journal offers the opportunity for ample space to develop an argument in full and the services of referees with expertise in mechanical behaviour and an understanding of the special nature of biomedical materials.

Examples of relevant subjects include:

• Stress/strain/time relationships for biological materials • Fracture mechanics of hard tissues • Tribological properties of joint materials and their replacements, including coatings • Mechanical characterisation of tissue engineering materials and scaffolds • The mechanical behaviour of cells, including adhesion • Response of cells to mechanical stimuli • Mechanical properties of biological molecules such as DNA • Long-term fatigue, creep and wear properties of biomaterials used in implants • The behaviour of the human body under impact loading • Mechanical performance all natural materials, including those from plants and animals • New techniques for the measurement of mechanical properties in biomedical materials, in both laboratory and clinical practice

• Computer simulations of material behaviour • Clinical case histories related to material performance

The journal publishes papers from the proceedings of the International Conference on the Mechanics of Biomaterials and Tissues; special issues devoted to particular subjects or events are also published from time to time.

Editor in Chief - David Taylor, Trinity College, Dublin, Ireland, Email: [email protected]

Associate EditorsF. O’Brien, Royal College of Surgeons, IrelandC. Simms, Trinity College, IrelandP. Vallittu, University of Turku, Finland

Editorial BoardT. Adachi, Kyoto University, JapanO. Akkus, Purdue University, USAG. Bao, Georgia Institute of Technology, USAM. Buehler, Massachusetts Institute of Technology, USAJ. Currey, University of York, UKS. Evans, Cardiff University, UKR. Geesink, Universiteit Maastricht, NetherlandsA. Gefen, Tel Aviv University, IsraelK. Hayashi, Okayama University of Science, JapanR. Ker, University of Leeds, UKJ. Kruzic, Oregon State University, USAC. Lee, Royal College of Surgeons, IrelandR.L. Mauck, University of Pennsylvania, USAR. McMeeking, University of California, USAMarc A. Meyers, University of California, San Diego, USAM. Niinomi, Tohoku University, JapanC. Oomens, Eindhoven University of Technology, The NetherlandsM. Oyen, University of Cambridge, UKP. Prendergast, Trinity College, IrelandR. Ritchie, University of California at Berkeley, USAR. Roeder, University of Notre Dame, USAH. Screen, Queen Mary, University of London, UKS. Suresh, Massachusetts Institute of Technology, USAM. Swain, University of Sydney, AustraliaS.H. Teoh, Division of Bio Engineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, SingaporeT. Tomsia, University of California at Berkeley, USAD. Vashishth, Rensselaer Polytechnic Institute, USAA. Wennerberg, University of Gothenburg, SwedenP. Zioupos, Cranfi eld University, UK

Printed in the Netherlands