BiologicalPsychiatry

A Journal of Psychiatric Neuroscience and Therapeutics

EditorJohn H. Krystal, MD

Yale University School of MedicineVA Connecticut Healthcare System

West Haven, Connecticut

Deputy EditorsAnissa Abi-Dargham, MD New York, New York

Edward T. Bullmore, MB, PhD, FMedSciCambridge, United Kingdom

Cameron S. Carter, MD Sacramento, California

Daniel Geschwind, MD, PhD Los Angeles, California

Paul J. Harrison, DM, FRCPsych Oxford, United Kingdom

Eric J. Nestler, MD, PhD New York, New York

Murray B. Stein, MD, MPH La Jolla, California

Editorial Committee Dennis S. Charney, MD David Goldman, MD Raquel E. Gur, MD, PhD K. Ranga Rama Krishnan, MD

New York, New York Rockville, Maryland Philadelphia, Pennsylvania Singapore

Ex Offi cioJohn G. Csernansky, MD Scott L. Rauch, MD Trey Sunderland, MD

Editorial BoardSchahram Akbarian, MD, PhD

Worcester, MA

Kazufumi Akiyama, MD, PhDTochigi, Japan

Amy F.T. Arnsten, PhDNew Haven, CT

Mark Baxter, PhDNew York, NY

Carrie E. Bearden, PhDLos Angeles, CA

Karen F. Berman, MDBethesda, MD

James Blair, PhDBethesda, MD

Antonello Bonci, MDSan Francisco, CA

David L. Braff, MDLa Jolla, CA

E. Sherwood Brown, MD, PhDDallas, TX

William A. Carlezon, Jr., PhDBelmont, MA

Edwin H. Cook, Jr., MDChicago, IL

Nick Craddock, MDCardiff, United Kingdom

Zafi ris Jeff Daskalakis,MD, PhD, FRCP(C)

Ontario, Canada

Karl Deisseroth, MD, PhDStanford, CA

Robert Desimone, PhDCambridge, MA

Ralph J. DiLeone, PhDNew Haven, CT

Ronald S. Duman, PhDNew Haven, CT

Klaus P. Ebmeier, MDOxford, United Kingdom

Stephen V. Faraone, PhDSyracuse, NY

Robert Freedman, MDDenver, CO

Karl J. Friston, MBBS, MA, MRCPsychLondon, United Kingdom

John D.E. Gabrieli, PhDCambridge, MA

Joel Gelernter, MDWest Haven, CT

Barbara Geller, MDSt. Louis, MO

David Goldman, MDRockville, MD

Anthony A. Grace, PhDPittsburgh, PA

Christian Grillon, PhDBethesda, MD

Ralitza Gueorguieva, PhDNew Haven, CT

Ahmad R. Hariri, PhDDurham, NC

Catherine J. Harmer, DPhilOxford, United Kingdom

Markus A. Heilig, MD, PhDBethesda, MD

Noboru Hiroi, PhDBronx, NY

Paul J. Kenny, PhDJupiter, FL

Joel E. Kleinman, MD, PhDBethesda, MD

George F. Koob, PhDLa Jolla, CA

K. Ranga Rama Krishnan, MDSingapore

Andrew D. Krystal, MD, MSDurham, NC

Ellen Leibenluft, MDBethesda, MD

David A. Lewis, MDPittsburgh, PA

Jeffrey A. Lieberman, MDNew York, NY

Barbara K. Lipska, PhDBethesda, MD

Stephen R. Marder, MDLos Angeles, CA

Athina Markou, PhDLa Jolla, CA

Graeme F. Mason, PhDNew Haven, CT

Christopher J. McDougle, MDLexington, MA

Andrew Mark McIntosh, MD, MRCPsych

Edinburgh, United Kingdom

Francis J. McMahon, MDBethesda, MD

Herbert Y. Meltzer, MDNashville, TN

Andreas Meyer-Lindenberg, MD, PhDMannheim, Germany

Emmanuel Mignot, MD, PhDPalo Alto, CA

Károly Mirnics, MDNashville, TN

Lisa M. Monteggia, PhDDallas, TX

Rajesh Narendran, MDPittsburgh, PA

Alexander Neumeister, MDNew York, NY

Charles P. O’Brien, MD, PhDPhiladelphia, PA

Michael C. O’Donovan, PhDCardiff, United Kingdom

Dost Öngür, MD, PhDBelmont, MA

Christos Pantelis, MD, MRCPsych, FRANZCP

Victoria, Australia

Martin P. Paulus, MDLa Jolla, CA

Godfrey Pearlson, MDHartford, CT

Mary L. Phillips, MDPittsburgh, PA

Daniel S. Pine, MDBethesda, MD

J. Daniel Ragland, PhDSacramento, CA

Judith L. Rapoport, MDBethesda, MD

Kerry Ressler, MD, PhDAtlanta, GA

Charles F. Reynolds, III, MDPittsburgh, PA

Trevor W. Robbins, PhDCambridge, United Kingdom

Jerrold F. Rosenbaum, MDBoston, MA

David R. Rosenberg, MDDetroit, MI

Christopher A. Ross, MD, PhDBaltimore, MD

Peter Roy-Byrne, MDSeattle, WA

David R. Rubinow, MDChapel Hill, NC

Scott J. Russo, PhDNew York, NY

Gerard Sanacora, MD, PhDNew Haven, CT

Akira Sawa, MD, PhDBaltimore, MD

Alan F. Schatzberg, MDStanford, CA

Edward M. Scolnick, MDCambridge, MA

Yavin Shaham, PhDBaltimore, MD

Larry J. Siever, MDBronx, NY

Dana Small, PhDNew Haven, CT

Matthew W. State, MD, PhDNew Haven, CT

Trey Sunderland, MDChevy Chase, MD

Stephan F. Taylor, MDAnn Arbor, MI

Laurence H. Tecott, MD, PhDSan Francisco, CA

Michael E. Thase, MDPittsburgh, PA

Gustavo Turecki, MD, PhDQuebec, Canada

Bruce I. Turetsky, MDPhiladelphia, PA

Myrna M. Weissman, PhDNew York, NY

Rachel Yehuda, PhDBronx, NY

Takeo Yoshikawa, MD, PhDSaitama, Japan

Carlos A. Zarate, Jr., MDBethesda, MD

Jon-Kar Zubieta, MD, PhDAnn Arbor, MI

Editorial Offi ce

Department of PsychiatryThe University of TexasSouthwestern Medical Center6363 Forest Park Road, Suite 651Dallas, Texas 75235-5435 USA

Telephone: (214) 648-0880Fax: (214) 645-9208e-mail: biol.psych@UTSouthwestern.eduwww.sobp.org/journal

Aims and Scope

This international rapid-publication journal is the offi cial journal of the Society of Biological Psychiatry. It covers a broad range of topics in psychiatric neuroscience and therapeutics. Both basic and clinical contributions are encouraged from all disciplines and research areas relevant to the pathophysiology and treatment of major neuropsychiatric disorders. Novel results of original research, in addition to Commentaries and Correspondence judged to be of high impact to the fi eld are published, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. Concise Reviews and Editorials that focus on topics of current research and interest are also published rapidly.

Administrative Editor Carol A. Tamminga, MDManaging Editor Rhiannon M. BugnoPublication Coordinator Rosa Garces

Founding EditorJoseph Wortis, MD, 1969-1992

Editor EmeritiWagner H. Bridger, MD, 1992-1997Richard C. Josiassen, PhD, 1997Dennis S. Charney, MD, 1998-2006