TEST1- PARTA

I Name

American Academy Larnaca

Year 3 Biology

• The total marks for this part is 20.• The total marks for the paper is 40.• The marks for each question are shown in square brackets.Use this as a guide as to how much time to spend on each question.

• Questions labelled with an asterisk (*) are ones where the qualityof your written communicationwill be assessed.You should take particular care with your spelling and grammar, as well as the clarity of expression,on these questions.

• Answer the questions in the spaces provided.There may be more space than you need.

-Answer ALL questions

Some questions must be answered with a cross in a box~.If you change your mind about an answer, put a line through the box S: and then

mark your new answer with a cross~.

Genetic disorders

1 The images show a normal red blood cell and a red blood cell from someone who hassickle cell disease. Sickle cell disease is a genetic disorder caused by two recessivealleles.

-

Normal red blood cellRed blood cell from someonewho has sickle cell disease

(a) (i) Complete the sentence by putting a cross ([8]) in the box next to your answer.

An individual with sickle cell disease is said to be

- 0 A a carrier for sickle cell disease

0 B heterozygous

[J C homozygous dominant

0 0 homozygous recessive

--

2

11111111111111111111111111111111111111111111111111111111111111111P41 931 A0216

-I

J

-(ii) Describe the main symptoms of sickle cell disease.

(3)

(b) (i) A female with the genotype (Dd) and a male with the genotype (DD) for sicklecell disease are about to start a family.

Complete the Punnett square to show the possible genotypes of theiroffspring for sickle cell disease.

Cl}

Female gametes

Male gametes

(ii) State the percentage chance that a child from these individuals will be(2)

II~. I,2. an individual with sickle cell disease " " %

II ~(~To~t~a~l~fo~r_Q~ue~s~t~io_n~1_=_8~m~a~r~k~s)~II II II I~ ]1.'~

Il..•.-..~~.~~~-~_-------------------_~_-.-.•..~-""

1. a carrier of sickle cell disease %

11111111111111111111111111111111111111111111111111111111111111111P 4 1 931 A 0 316

3 -Turn over?

Q2.I

The photograph shows a sinqle-celled bacterium.

(a) (i) Complete the sentence by putting a cross ( [gI ) in the box next to your answer.Bacteria are classified into the kingdom

0(1)

A animalia[J B plantaeEl C fungiD 0 prokaryota

(ii) Complete the sentence by putting a cross ( cgJ ) in the box next to your answer.Bacteria do not contain

E3 A a cell membraneC3 B ace" wallEJ C a nucleusEJ 0 chromosomes

(1)

(b) Viruses are not classified into any kingdom.

Describe what a virus does after it has entered its host.(2)

(c) All vertebrates have a backbone and are classified into groups.

(i) Use words from the box to complete the sentences about one method of classification.(2)

VIViparous hybrids

oetparous

consumersII

chordates

Once fertilisation has occurred some vertebrates lay eggs. Vertebrates that lay eggs are known

as Vertebrates that give birth to live young are known as .

(Total for Question is 6 marks)

-

x y z

Genetic inheritance

''3 The family pedigree shows the inheritance of sickle cell disease through threegenerations.

firstgeneration

secondgeneration

thirdgeneration

Key

o = unaffected female D= unaffected male

{~,I,

e= affected female 11= affected male

U = carrier female IJ = carrier male

(a) (i) Calculate the percentage of the offspring from the first generation who areheterozygous for sickle cell disease.

IIII ..· · ··..·····..··..· ··..· .~I .If

I1I

.........................................................................%

(ii) Explain why the offspring produced by the first generation parents are not thesame as those predicted in a Punnett square.

I~__~ ._._---.J18

1111111111111111111111111111111111111111111111111111111111111111111111P 4 1 9 5 5 A 0 1 820-

-(iii) Person Wand his partner have a third child. 1

State the probability that this child will have sickle cell disease.

Complete the Punnett square to show this.{2}

I I

II ,

!!I I

I II

probability .

(iv) Complete the sentence by putting a cross (181)in the box next to your answer.

The genotype of person V isCO

D A homozygous dominant -0 B homozygous recessive -0 C heterozygous -0 D carrier -

1111111111111111111111111111111111111111111111111111111111111111111111P 4 1 9 5 5 A 0 1 920

19 -Turn over ~

Part A

Q1 a) i) D

ii) tired

short of breath

aching joints

b) i)

ii) 1. 50 2. 0

Q2 a) i) D ii) C b) causes cell/nucleus… …to make copies of virus c) i) oviparous viviparous Q3 a) i) 75 ii) Punnett square gives only probability of each type of genotype. iii)

50% iv) A Part B Q1 a) i) B ii) chordata b) 1 unicellular 2 simple cell structure/no nucleus c) Any two from:

variations within species hybrids many species do not reproduce sexually similar characteristics can be seen in different species same common name d) fish wet scales, gills, external fertilisation, oviparous, poikilothermic

amphibians moist skin, adults have lungs but oxygen can also diffuse through skin, external fertilisation, oviparous, poikilothermic

reptiles dry scaly skin, lungs, internal fertilisation, leathery-shelled eggs, poikilothermic mammals feathers, beak, lungs, internal fertilisation, oviparous, homeothermic birds hair, produce milk, lungs, internal fertilisation, viviparous, homeothermic Q2 i) nucleus ii) A iii) 1 difficult to breathe

2 difficulty in digestion/weight loss Q3 a) i) Any two from:

vertebrae beak heterotrophic skeleton/bones

ii) backbone iii) B