Diagnosis, Pathophysiology and Management of Vertigo

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    Meiti Frida, MD

    Neurology Department M Djamil Hospital/AndalasUniversity

    DIAGNOSIS,PATHOPHYSIOLOGY

    AND MANAGEMENT OF

    VERTIGO 

    geran Beach Hotel , Jan !th" #$%

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    OUTLIN

    !" Introdu#tion De$nition vertigo

    tiology

    %" &at'op'ysiology vertigo

    (" Diagnosis vertigo

    )" Treatment vertigo

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    DFINITION

    *ertigo

    +ommon medi#al pro-lem

    +(. o0 people average 12 years

    +%. o0 all older person see3 medi#aladvi#e

    *ertigo 4 T'e sensation o0 spinning orevolving5'ile t'e -ody is stationary 5it' respe#tto t'e eart' or surrounding

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    %" Neurology %( 8 (. #ase ere-rovas#ular disorder ;TIA < =tro3e Neuropat'y ata:ia Multiple s#lerosis =ervi#al disorder  Tumor ;a#usti# neuroma<

    'iari mal0ormation ere-ellum Disorder

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    (" =ystemi# ause(( #ardiovas3uler disorder>? 9lood pressure

    Arit'mia #ordisUremia>? 6ly#emia

    In0e#tionDrug into:i#ation 4 Ni0edipin,-en@odia@epin, :ana:

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    )" &sy#'iatry 2. #ase

    Depression

    Fo-ia

    An:ietas

    &si#'osomati#

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    &at'op'ysiology *ertigo

    Be#eptor Data&ro#essing

    0e#tor

    • ye• *esti-uler

    • &roprio#eptive

    N= • =#letal Mus#le• ye

    • =ervi#al• 9ody• :tremities

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    NOBMAL &BO==IN6

    Ve&t'()lar &*&te+

    '&)&Pro-r'oce- t'e

    =ensoryIn0ormation

    entral

    O#ulomotor

    #entral

    Mus#les o0 t'e-ody

     C #oordinated

     C 3no5n pattern

    sta-ili@ation o0 visual $eld

     stati# and 3ineti# euili-rium

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    Hea.Accelerat'on

    Hea. Ang)larVeloc't*

    En.ol*+-hD'&-lace+ent

    /'l'a

    Ben.'ngRece-tor /ellPotent'al

    S*na-t'c

    Act'on

    /)-)lar

    Angle

    Generator-otent'al

    Pr'+ar*

    a0erentact'on-otent'al

    /NS

    VOR-rece-t'o

    -o&t)re

    Eet 4N= 4 #entral Nervous =ystem*OB 4 *esti-ulo O#ular Bee:

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    DIA6NO=IN6 *BTI6O

    Anamnesis

    • G'at symptom you 'ave 0or e:ample 5et'er you0eel lig't 'eaded or i0 your surrounding are spinning

    • Ho5 o0ten your symptom o##ur

    • Ho5 long you symptoms usually lost 0or

    • I0 your symptom are ae#ting your daily a#tivities0or e:ample, 5et'er you are una-le to 5al3 duringon episode o0 vertigo

    • Have a 0amily 'istory o0 migraine or menieredisease

    • Have re#ently 'ad an in0e#tion or 'ead injury

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    &'ysi#al e:amination

    • 9lood pressure 4 'ipotensi ort'ostati#• Heart rate ryt'm

    • 9ruit #arotis

    Neurology e:amination

    • A5arness

    • Nn ranialis

    • Motori#

    • =ensori#

    • =ere-elum

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    Ot'er Test

    • Hallpi3esManouvre

    • Manuver *alsava

    • Nylen 9arany Test

    • alori Test

    Hallpi3es Manouvre

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    • Hearing test4 Tinnitus,

    Hearing Loss – Audiometry Test – Tuning 0or3 Test

    • MBI s#an 4 A#ousti#

    Neuroma• Bom-erg test• 9A&

    Bom-erg test

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    *ertigoOtogeni3

    Neurogeni3

    !" Type

    %"Dire#tion

    Botatorydire#tional'ori@ontal

    Botatory

    Non rotational

    Hori@ontal,rotatory

    s#otoma

    I" *BTI6O

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    a"Po&'t'onchange&

    (" Ga't.'&t)r(anc

    e

    c" A)tono)+.*&1)nct'on

    ." Other&&*+-to+&

    In2)ence (*hea.-o&'t'on3(o.*

    Rarel*

    Al4a*&

    T'nn't)&,hear'ng lo&&De5c'tne)rolog'c 1ocal

    678

    In2)ence (*nec9 +ot'on

    o1ten

    Rarel*

    I+-a're.con&c'o)&ne&&De5c'tne)rolog'c1ocal 6:8

    II" &'ysi#al Diagnosis

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    a"D'rect'on In.'rect'on B'.'rect'on-" Type Hori@ontal or

    rotatory'ori@ontal

    Botatoryverti3al, do5n-eat, up -eat

    #" ye $:ation -lo#3ing Non -lo#3ingd" Nystagmus

    positionalBepeat DiJ#ult asy repeated

    e" ye

    tra#3ing

    sinusoid =a##adi#/ata:i#

    0" alory Unilateral5ea3ness

    9ilateral5ea3ness

    III" Nystagmus e:amination

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    a" Bom-erg test  Mata ter-u3a  Mata tertutup

    Normala-normal

    A-normalA-normal

    -" Griting test Deviasi a-normal Ata:ia / 5ave

    #" Ata:ia none o0ten

    d" Finger to $ngertest

    Normal A-normal

    e" &ast pointingtest

    A-normal -ot''ands

    A-normal side o0lesion

    0" =tepping Deviation o0 sideo0 lesion

    rrati# deviation

    g" Gal3ing eye #losed T'ere aredeviation

    ye #losed andopen are deviation

    I*" *esti-ulo spinal e:amination

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    Depend upon t'e su-type and #auseidenti$ed

    • =upporti0 • =imptomati#

    • ausati0

    • Operati0

     Treatment o0 *ertigo

    I = t ti T t t

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    I" =ymptomati# Treatment

    Anti 'istamine

    Dymen 'ydrinate ( : 2.mg/day

    innari@ine ( : %2mg/day

    a+entry -lo#3er

    Flunari@ine ( : 2+ !.mg/dayHistamini#

    9eta'istine ;merislon< ( : Kmg/day

    Fenotia@ine'lorproma@ine ( : %2mg/day

    Meto#lopramide

    &rimperan ( : !.mg/day

     Treatment

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    ausative Treatment

    Anti platelet agregationOperati0   Tumor =pondylosis servi3alis

    pilepsi &'enitoin ar-ama@epin

    Migrain

    rgotamine Flunari@ine

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    Be'a-ilitati0 Treatment

    + Metode 9randt+Daro 

    + 6ait e:er#ise

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     ZI-MING W, ET AL. THE EFFECT OF BETAHISTINE MESYLATE AS A TREATMENT TO VERTIGO INDUCED BY INNER

    EAR ISCHEMIA. CHINESE SCIENTIFIC JOURNAL OF HEARING & SPEECH REHABILITATION 2!

     

    T"# E$$#% '$ B#(")*)+# M#*(#(* ( T#(/#+ ' V#)0' I+1%#13 I++# E( I*%"#/)(

    O34 )

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    O34#%)5#

    T' '3*#5# "# #$$#%* '$ 3#(")*)+# /#*(# (* ( #(/#+ '

    3#+)0+ 6'*))'+( 6('7*/( 5#)0' 8BPPV9, 6'*#)' %)%()'+

    )*%"#/)( 8PCI9, /)0()+'* 5#)0' 8MV9 (+1 ##+(0# 3#+)0+6('7*/( 5#)0' (+1 ' *1 "# %(*( #()'+*")6* '$ 1'*(0#*

    3#:##+ 3#(")*)+# /#*(# ; /0 &

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    6rouping o0 patients

    &arameter Hig' stimulating rate o0 auditory -rainstemresponse ;A9B<

    Di@@iness 'andi#ap inventory ;DHI<

    A9B DHI -e evaluated #ompared -e0ore a0teradminstration o0 -eta'istine mesylate

     Total pasien nC P.

    9&&* &I M*(. pasien (. pasien (. pasien

    MB= 1 mgMB= !% mgMB= 1 mgMB= !% mgMB= 1 mgMB= !% mg!2 patients!2 patients!2 patients!2 patients!2 patients!2 patients

    i+ming G, et al" T'e e#t o0 9eta'istine Mesylate as a Treatment to *ertigo Indu#ed -yInner ar Is#'emia" 'inese =#ienti$# ournal o0 Hearing =pee#' B'a-ilitation %..

    P B ") ) M

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    pQ.".! pQ.".!pQ.".2

    #*)/6(+ E$)(*) 1)+4(+ '#" #1( 06 3() ; /0 /(6+

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    nCP.

    &eere

    +'l.

    i+ming G,et al" T'e ee#t o0 -eta'istine mesylate as a treatment to vertigo indu#ed -y inner ear is#'emia" %..

    #*)/6(+ E$)(*) 1)+4(+ '#" #1( 06 3() ; /0 /(6+

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    9eta'istine Mesylate !%mg, ( : se'ari ditoleransi dengan-ai3 ole' pasien *ertigo dan Di@@iness"

    Dari #"#;

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    • *ertigo is pu-li# 'ealt' pro-lemespe#ially in t'e elderly

    • Need anamnesis and e:aminationas 5ell as t'e etiology o0 vertigo

    •  Treatment depends on t'e su-type

    and #ause

    on#lusion

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