30
Departament de Medicina Programa de Doctorat en Medicina TESI DOCTORAL DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY DECLINE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE Autora: Maria Antònia Ramon Belmonte Directors: Judith Garcia Aymerich Centre for Research in Environmental Epidemiology Jaume Ferrer Sancho Hospital Universitari Vall d’Hebron BARCELONA, 2015

DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

  • Upload
    others

  • View
    2

  • Download
    0

Embed Size (px)

Citation preview

Page 1: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Departament de Medicina

Programa de Doctorat en Medicina

TESI DOCTORAL

DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY DECLINE IN PATIENTS WITH CHRONIC

OBSTRUCTIVE PULMONARY DISEASE

Autora:

Maria Antònia Ramon Belmonte

Directors:

Judith Garcia Aymerich Centre for Research in Environmental Epidemiology

Jaume Ferrer Sancho Hospital Universitari Vall d’Hebron

BARCELONA, 2015

Page 2: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

ANNEX 2

Articles published in the frame of the present doctoral thesis

Page 3: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,
Page 4: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

149

INSPIRATORY CAPACITY-TO-TOTAL LUNG CAPACITY RATIO AND DYSPNOEA PREDICT EXERCISE CAPACITY

DECLINE IN COPD

Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A, Farrero E, Gea J, Barberà JA, Agustí A, Rodriguez-Roisin R, Antó JM, Garcia-Aymerich J.

Accepted for publication in Respirology on the 3th of September 2015.

Page 5: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,
Page 6: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

151

Page 7: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

152

Page 8: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

153

Page 9: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

154

Page 10: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

155

Page 11: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

156

Page 12: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

157

Page 13: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

158

Page 14: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

159

Page 15: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

160

Page 16: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

161

Page 17: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

162

Page 18: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

163

Page 19: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

164

Page 20: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

165

Page 21: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

166

Page 22: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

167

Page 23: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

168

Page 24: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

169

Page 25: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

170

Page 26: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

171

Page 27: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

172

Page 28: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

173

Page 29: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

174

Page 30: DETERMINANTS AND EFFECTS OF EXERCISE CAPACITY …Ramon MA, Ferrer J, Gimeno-Santos E, Donaire-Gonzalez D, Rodríguez E, Balcells E, Batlle J, Benet M, Guerra S, Sauleda J, Ferrer A,

Annex II

175