16
42 DAFTAR PUSTAKA 1. Sandesc, Dorel.Sepsis: A Review.Timosoura Medical Journal [ internet ].2003 [ cited 2014 february 12 ];Available from : Timosoura Medical Journal 2. Medlineplus.Sepsis.[ internet ]. [ 11 February 2014 ; cited 12 february 2014 ].Available from :http://www.nlm.nih.gov/medlineplus/sepsis.html. 3. Griffiths Ben , Anderson D lain . Sepsis , SIRS , and MODS .Surgery [ internet ] .Oktober 2009 [ cited 11 february 2014 ] 27, ( 10 ) , 446-449. 4. Martin GS, Mannino DM, Eaton S, Moss M. . The epidemiology of sepsis in the united states from 1979 through 2000 . N Engl J Med [ internet ] . 2003 ; [ cited 11 february 2014 ] ; 384 ( 16 ) : 1546 54 5. Angus, D.C., walker T , Linda , Jefrey , Josep carlito ,Michael pinsky . Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care . Crit. Care Med [ internet ] . 2001 [ cited 11 February 2012 ].. 29:1303-1310. 6. Harrison DA, Welch CA, Eddleston JM. The epidemiology of severe sepsis in England, Wales and Northern Ireland, 1996 to 2004: secondary analysis of a high quality clinical database, the ICNARC case mix programme database. Crit Care [Internet]. 2006 [cited 2012 feb 16;10(2):R42. Availabel from: PubMed 7. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med [Internet]. 2003 [cited 2012 Feb 16;348:1546-54]. Available from: PubMed 8. Dachlan EG ( 2009 ) Obstetrical sepsis IN the 10 th Annual Indonesian Maternal Fetal Medicine Scientific Meeting .

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DAFTAR PUSTAKA

1. Sandesc, Dorel.Sepsis: A Review.Timosoura Medical Journal [ internet ].2003

[ cited 2014 february 12 ];Available from : Timosoura Medical Journal

2. Medlineplus.Sepsis.[ internet ]. [ 11 February 2014 ; cited 12 february 2014

].Available from :http://www.nlm.nih.gov/medlineplus/sepsis.html.

3. Griffiths Ben , Anderson D lain . Sepsis , SIRS , and MODS .Surgery [

internet ] .Oktober 2009 [ cited 11 february 2014 ] 27, ( 10 ) , 446-449.

4. Martin GS, Mannino DM, Eaton S, Moss M. . The epidemiology of sepsis in

the united states from 1979 through 2000 . N Engl J Med [ internet ] . 2003 ;

[ cited 11 february 2014 ] ; 384 ( 16 ) : 1546 – 54

5. Angus, D.C., walker T , Linda , Jefrey , Josep carlito ,Michael pinsky .

Epidemiology of severe sepsis in the United States: analysis of incidence,

outcome, and associated costs of care . Crit. Care Med [ internet ] . 2001 [

cited 11 February 2012 ].. 29:1303-1310.

6. Harrison DA, Welch CA, Eddleston JM. The epidemiology of severe sepsis in

England, Wales and Northern Ireland, 1996 to 2004: secondary analysis of a

high quality clinical database, the ICNARC case mix programme database.

Crit Care [Internet]. 2006 [cited 2012 feb 16;10(2):R42. Availabel from:

PubMed

7. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in

the United States from 1979 through 2000. N Engl J Med [Internet]. 2003

[cited 2012 Feb 16;348:1546-54]. Available from: PubMed

8. Dachlan EG ( 2009 ) Obstetrical sepsis IN the 10th

Annual Indonesian

Maternal Fetal Medicine Scientific Meeting .

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43

9. Soreng, Katherine, Ph.D., Levy, Roma, M.S. Procalcitonin: an Emerging

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„golden hours‟. Critical Care Medicine [Internet]. 2006 [cited 2011 Nov

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31. O’Callaghan C. At a Glance Sistem Ginjal (Terjemahan). 2nd ed. Safitri A,

Astikawati R, editors. Jakarta: Penerbit Erlangga; 2009.

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MS, Setiati S, editors. Buku ajar Ilmu Penyakit Dalam. 1 ed. Jakarta: Pusat

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Indonesia. Perhimpunan Dokter Paru Indonesia: 2003. hal 1-56 .

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39. McKinlay J, Bihari D. Multiple organ dysfunction. Dalam: Bersten AD, Soni

N, Oh TE [ed.]. Oh’s intensive care manual. 5th ed London: Butterworth

Heinemann. 2003.p.113-26.

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outcome. Crit Care Med. 1995;23 (10):1638-52.

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intensive care treatment in very elderly patient : a review . Critical Care. 2005

; 307 – 14.

43. Vera , Evacuasinya Endang , Richardo Yuvens. Karakteristik Pasien Usia

Lanjut di Ruang Rawat Intensif Rumah Sakit Immanuel Bandung .2011 Feb 2

. Jurnal JKM.10:110-119.

44. Sistem manajemen RSUP dr. Kariadi . Kebijakan RSUP dr. Kariadi .

Semarang . Februari 2013.

45. Departemen Kesehatan . Standart Pelayanan ICU . Available from : <

http://www.depkes.go.id>(Accesed 27 September 2012 ).2008.

46. Vosylius S,Sipylaite J, Ivaskevicius J. Determinant of outcome in elderly

patient admitted to the intensive care unit . J Age and ageing .2005 ; 34 : 157

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Sepsis in European intensive care units: results of the SOAP study. Crit Care

Med [internet]. 2006 [cited 2010 Oct 4]. 34(2):344-353. Available from:

http://www.ccmpitt.com

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48. Sunaryo Aries, Sri Redjeki Ike, Bisri tatang. Perbandingan validasi APACHE

II dan SOFA score untuk memperkirakan mortalitas pasien yang dirawat di

ruang perawatan intensif.2012.2: 1 :

49. Roberto Ceriani, Maurizio Mazzoni, Franco Borton.Application of the

Sequential Organ Failure Assesment Score to cardiac Surgical patient.

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Use of the SOFA score to assess the incidence of organ dysfunction/failure in

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Med [internet]. 1998 26(11), pp 1793-1800

51. Osborn, Tiffany Medlin MD,Tracy, J Kathleen PhD et all.Epydemiology of

sepsis in patient with traumatic injury. Critical Care Medicine.2004.11.23

52. Alfani , Diana Lalenoh dkk .Hubungan skor SOFA dengan lama rawat inap

pasien cedera kepala berat di ICU RSUP prof. Dr. R. D. Kandou Periode juni

2012- oktober 2013.

53. Bakker J, deLima AP. Increased blood lactate levels: An important warning

signal in surgical practice. Crit Care Med. 2004; 8: 96-7.

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LAMPIRAN

LAMPIRAN 1. Biodata Penulis

Identitas

Nama : Nurul Ahmad Isnaini

NIM : 22010110130187

Tempat/Tanggal lahir : Lamongan, 16 Oktober 1991

Jenis Kelamin : Laki - laki

Alamat : Jln. Bulusan Selatan

No HP : 085641695349

Email : [email protected]

Riwayat Pendidikan Formal

1. SD : SDN Balun 2

2. SMP : SMPN 1 Lamongan

3. SMA : SMAN 2 Lamongan

4. Universitas : FK UNDIP

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Lampiran 2. Ethical Clearance

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Lampiran 3. Surat Izin Penelitian

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Lampiran Data Output

1. Data kategorik

a. Jenis Kelamin

Jenis Kelamin

Frequency Percent Valid Percent Cumulative

Percent

Valid

Laki - laki 27 60.0 60.0 60.0

Perempuan 18 40.0 40.0 100.0

Total 45 100.0 100.0

b. Penyakit Komorbid

Penyakit Komorbid

Frequency Percent Valid Percent Cumulative

Percent

Valid

Stroke 5 11.1 11.1 11.1

Gagal Ginjal 3 6.7 6.7 17.8

DM 3 6.7 6.7 24.4

Tumor 5 11.1 11.1 35.6

HAP 1 2.2 2.2 37.8

DIC 5 11.1 11.1 48.9

Pneumonia 14 31.1 31.1 80.0

Infeksi 2 4.4 4.4 84.4

PPOK 2 4.4 4.4 88.9

CHF 1 2.2 2.2 91.1

AIHA 1 2.2 2.2 93.3

HIV Aids 1 2.2 2.2 95.6

Peritonitis 1 2.2 2.2 97.8

SNH 1 2.2 2.2 100.0

Total 45 100.0 100.0

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c. Usia Skor < 9

Usia Skor < 9

N Minimum Maximum Mean Std. Deviation

skor < 9 21 18 70 49,48 18,052

Valid N (listwise) 21

d. Usia > 9

Usia > 9

N Minimum Maximum Mean Std. Deviation

Skor > 9 24 23 70 52,63 13,197

Valid N (listwise) 24

e. Hidup / meninggal < 9

skor < 9

Frequency Percent Valid Percent

Cumulative

Percent

Valid 24 53,3 53,3 53,3

hidup 5 11,1 11,1 64,4

meninggal 16 35,6 35,6 100,0

Total 45 100,0 100,0

f. Hidup / meninggal > 9

Skor > 9

Frequency Percent Valid Percent

Cumulative

Percent

Valid 21 46,7 46,7 46,7

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meninggal 24 53,3 53,3 100,0

Total 45 100,0 100,0

2. Uji Normalitas

Tests of Normality

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

SkorSofa ,171 45 ,002 ,929 45 ,008

LamaRawat ,207 45 ,000 ,781 45 ,000

a. Lilliefors Significance Correction

3. Uji korelasi Spermen

Correlations

TransSofa TransRawat

Spearman's rho TransSofa Correlation Coefficient 1,000 -,214

Sig. (2-tailed) . ,158

N 45 45

TransRawat Correlation Coefficient -,214 1,000

Sig. (2-tailed) ,158 .

N 45 45

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DATA PENELITIAN

KORELASI ANTARA SKOR SOFA DENGAN LAMA RAWAT INAP PASIEN

SEPSIS

DI ICU RSUP DR KARIADI

NO NO.CM UMUR JENIS KELAMIN KOMORBID

NILAI SKOR SOFA 1

NILAI SKOR SOFA 2

NILAI SKOR

LAMA HARI RAWAT

skor < 9

Skor > 9 Skor < 9 Skor >9 skor < 9 skor > 9

1 C 389415 59 laki Stroke 13 16 16 2 59 Stroke meninggal

2 C 395205 61 Perempuan

Gagal Ginjal 5 9 9 17 61 gagal ginjal meninggal

3 C 392367 34 Laki DM 12 12 17 34 DM meninggal

4 C 392186 51 Perempuan Tumor 12 8 12 1 51 Tumor meninggal

5 C 400417 63 laki HAP 5 5 8 63 Hap meninggal

6 C 380110 45 laki DIC 9 9 9 7 45 DIC meninggal

7 C 396745 70 Perempuan Pneumonia 6 7 7 9 70 Pneumonia meninggal

8 C 359592 18 Perempuan Pneumonia 6 6 6 20 18 Pneumonia meninggal

9 C 396092 23 laki Infeksi 10 9 10 39 23 Infeksi meninggal

10 C 400132 65 laki PPOK 5 5 5 10 65 PPOK meninggal

11 C 115712 70 laki PPOK 8 9 9 2 70 PPOK meninggal

12 C 247852 60 laki Pneumonia 6 5 6 17 60 Pneumonia hidup

13 C 392582 20 laki Pneumonia 6 5 6 17 20 Pneumonia hidup

14 C 393842 54 Perempuan DIC 15 11 15 12 54 DIC meninggal

15 C 396293 37 laki Pneumonia 9 9 2 37 Pneumonia meninggal

16 C 60 laki Tumor 9 9 3 60 Tumor meninggal

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403513

17 C 397883 50 laki

Gagal Ginjal 5 5 10 50 gagal ginjal hidup

18 C 401973 70 Perempuan Pneumonia 12 12 6 70 Pnemonia meninggal

19 C 400603 63 Perempuan Pneumonia 17 17 17 2 63 Pneumonia meninggal

20 C 397823 70 Perempuan Stroke 14 14 2 70 Stroke meninggal

21 C 401148 49 Laki CHF 8 8 1 49 CHF hidup

22 C 396639 63 Perempuan Tumor 7 9 9 9 63 Tumor meninggal

23 C 400794 35 laki

Gagal Ginjal 15 12 15 1 35 gagal ginjal meninggal

24 A 548574 50 laki Pneumonia 14 13 14 1 50 Pneumonia meninggal

25 A 401496 58 laki DIC 19 18 19 4 58 DIC meninggal

26 C 403277 70 laki DIC 7 7 8 70 DIC meninggal

27 C 380540 28 Perempuan Infeksi 4 4 9 28 Infeksi meninggal

28 C 279140 25 Perempuan Pneumonia 7 8 8 31 25 Pneumonia meninggal

29 C 404070 66 laki Stroke 11 12 12 4 66 Stroke meninggal

30 C 401039 39 Perempuan AIHA 4 4 4 39 AIHA meninggal

31 C 401799 30 laki HIV Aids 8 7 8 8 30 HIV Aids meninggal

32 C 402848 38 Laki Peritonitis 8 8 8 6 38 Peritonitis meninggal

33 C 086769 57 Perempuan Pneumonia 7 7 17 57 Peritonitis meninggal

34 C 398309 34 Perempuan Tumor 5 5 2 34 Tumor meninggal

35 C 403755 34 Laki DM 14 11 14 38 34 DM meninggal

36 B 240467 43 Perempuan Pneumonia 15 17 17 5 43 Pneumonia meninggal

37 C 069721 45 laki Stroke 15 15 15 30 45 Stroke meninggal

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38 C 401496 58 laki Pneumonia 17 18 18 4 58 Pneumonia meninggal

39 C 325971 55 laki SNH 8 8 14 55 SNH hidup

40 C 398921 50 Laki DIC 11 11 1 50 DIC meninggal

41 C 405251 66 Perempuan Tumor 4 4 3 66 Tumor meninggal

42 B 216650 62 laki DM 4 4 5 62 DM meninggal

43 C 221502 70 Perempuan Pneumonia 4 4 6 70 Pneumonia meninggal

44 C 130393 70 laki Pneumonia 4 4 4 70 Pneumonia meninggal

45 C 246013 64 Perempuan Stroke 9 9 3 64 Stroke meninggal

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Lampiran 6. Dokumentasi Penelitian