What is it?Recessive genetic diseaseThick mucusClogs the lungsHard to breatheAffected parts: lungs & reproductive cells

SYMPTOMSSkin taste salty Persistent coughWheezingRepeated lung infectionsFoul smellWeight loss

EFFECTSLung blockageBacterial infectionsIncomplete digestionLess fertilityDamage to insulin producing cells

CAUSESMutation (phenylalanine)Defective CFTR proteinLess efficient transportation of chloride ionsNo envt affects

Autosomal recessiveNot sex linked (both parents need to have the defect) Chromosome 7

TREATMENTSMucus thinnersAntibioticsAnti-inflammatoryBronchodilators

Newborn screeningSweat testBlood testGenetic counseling availableLife expectancy: mid 30sDisturbances in normal life

Very common in Caucasians (1 in every 2500 people) than in any other ethnic group (1 in every 17,000 people).

Chart1

3

1

Series 1

Sheet1

Series 1

Caucasians3

Others1

To resize chart data range, drag lower right corner of range.

New molecules identified to ease the symptoms of CFCystic Fibrosis Drug Bronchitol ApprovedWhy bacterial infections deadly in CF

EXTRA CREDIThttp://www.youtube.com/watch?v=0BYtm4GwoZw

CITATION

Alma, L. (2008, June 30).About.com. Retrieved from http://cysticfibrosis.about.com/od/cysticfibrosis101/a/organs.htm

Mayo Clinic Staff. (2010, March 02).Mayo clinic. Retrieved from http://www.mayoclinic.com/health/cystic-fibrosis/DS00287/DSECTION=symptoms

(n.d.). Retrieved from http://www.tree.com/health/cystic-fibrosis-genetics.aspx

Cystic Fibrosis Foundation. (2011, August 22).Frequently asked questions. Retrieved from http://www.cff.org/AboutCF/Faqs/

How is cf diagnosed?. (n.d.). Retrieved from http://www.cff.org/AboutCF/Faqs/

Genetics home reference. (2012, April 16). Retrieved from http://ghr.nlm.nih.gov/condition/cystic-fibrosis

(04 1). New medication effectively treats underlying cause of cystic fibrosis. Retrieved from http://www.medicalnewstoday.com/sections/cystic_fibrosis/

1*3**6*7*9*