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CURRICULUM VITAE

Hemant Kumar Tiwari, M.S., Ph.D.

William “Student” Sealy Gosset Endowed Professor in Biostatistics OFFICE ADDRESS HOME ADDRESS Department of Biostatistics 749 Sussex Drive Ryals Public Health Bldg 420C Vestavia Hills 1665 University Blvd. AL 35226 University of Alabama at Birmingham (205) 824-9442 Birmingham, AL 35294-0022 (205) 934-4907 (216) 975-2540 fax htiwari@uab.edu CITIZENSHIP United States of America EDUCATION Post Doctoral Fellow: Jul 1995 – Jun 1996, under Dr. R. C. Elston Department of Epidemiology and Biostatistics Case Western Reserve University, Cleveland, Ohio Post Doctoral Fellow: Jul 1993 – Jun 1995, under Dr. R.C. Elston. Department of Biometry and Genetics LSU Medical Center, New Orleans, Louisiana. Ph.D.: August 1986, University of Notre Dame, Indiana. Area: Mathematics (Algebra). M.S.: December 1983, University of Notre Dame, Indiana.

Area: Mathematics (Topology, Algebra, Real & Complex Analysis, Algebraic Geometry, Algebraic Topology, Differential Geometry, Algebraic Topology)

M.Sc.: May 1978, Indian Institute of Technology, Kanpur,

India. Area: Pure and Applied Mathematics (Topology, Algebra, Real & Complex Analysis, Number Theory, Functional Analysis, Numerical Methods, Operational Research, Graph Theory)

B.Sc.: May 1976, University of Kanpur, Kanpur, India.

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Majors: Mathematics, Physics, and Statistics. OTHER TRAINING: Attended Professional Development Workshop Series: “Promotion and Tenure in Academic Career Development”, August 27, 2010, The University of Alabama at Birmingham. Attended Professional Development Workshop Series: “The Road to Meeting One’s Scholarship Goals: Leadership”, April 17, 2009, The University of Alabama at Birmingham. Attended ENAR Short Course, “Statistical Modeling and Analysis of Brain Imaging Data”, in ENAR Meeting, March 15-182009. Attended Professional Development Workshop Series: “On the Road to Meeting One’s Scholarship Goals: How to be a mentor”, February 19, 2009, The University of Alabama at Birmingham. Propensity Score and Instrumental Variables: Moving from Novice to Expert, organized by UAB Deep South Musculoskeletal CERTs and UAB Center for Outcomes & Effectiveness Research Education, March 5, 2008, The University of Alabama at Birmingham. The New Genetics Workshop organized by Clinical Nutrition Research Center, February 15, 2008, The University of Alabama at Birmingham. A course in R, Dr. Lumly, February 27-28, 2006, The University of Alabama at Birmingham. A course in Missing Data, Paul D. Allison, Aug 2005, The University of Alabama at Birmingham. A Course in Multiple Comparisons and Multiple Tests, Peter H Westfall, Aug 2005, Joint Statistical Meeting, Minneapolis, MN Genetic Admixture Workshop, Minority Health & Research Center, May 2005, The University of Alabama at Birmingham. Applied Longitudinal Data Analysis: Modeling Change and Event Occurrence, Judith D Singer, April 2005, The University of Alabama at Birmingham. Semiparametric Estimation of Average Treatment Effects under Exogeneity, Guido Imbens, Jan 2004, The University of Alabama at Birmingham. Treatment of Missing Data Via Multiple Imputation and Maximum Likelihhod,

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Paul D. Allison, Nov 2004, Baltimore, MD Developing Scientific Manuscripts, Dale Benos, Oct 2004, The University of Alabama at Birmingham. Bayesian Biostatistics: Introduction and Recent Advances, Jan 2003, University of Texas, MD Anderson Cancer Center. Microarray Data Analysis, Russ Wolfinger, Mar 2002, ENAR, Arlington, VA. Statistical Integration of Genetic Information Across Data Domains: Biomedical, Agricultural, and Comparative Genomics, Dec 2002, IMS Sponsored Mini-Conference, The University of Alabama at Birmingham. Design & Analysis of Recombinant Inbred Strain Experiments, May, 2002, UAB. SAGE workshop, Aug 1999, Case Western Reserve University, Cleveland. Advanced Linkage Course, Sept 1997, Rockefeller University, New York. PROFESSIONAL APPOINTMENTS: Oct 2011 – Present Professor Section on Statistical Genetics

Department of Biostatistics University of Alabama at Birmingham, Birmingham Alabama

Oct 2011 – Oct 2015 Head of the Section on Statistical Genetics Department of Biostatistics University of Alabama at Birmingham, Birmingham Alabama

July 2011 – Sept 2011 Interim Head of the Section on Statistical Genetics

Department of Biostatistics University of Alabama at Birmingham, Birmingham Alabama

April 2010 – Present William “Student” Sealy Gosset Endowed

Professorship in Biostatistics University of Alabama at Birmingham, Birmingham Alabama

Feb 2009 – Present Clinical Nutrition Research Center University of Alabama at Birmingham, Birmingham

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Alabama July 2007 – Present: Affiliated Faculty Member Department of Biology and Wildlife College of Natural Science and Mathematics

University of Alaska Fairbanks, Alaska

May 2006 – Sept 2011: Associate Professor Section on Statistical Genetics

Department of Biostatistics University of Alabama at Birmingham, Birmingham, Alabama

Jan 2002 – April 06: Assistant Professor Department of Pathology,

Division of Molecular and Cellular Pathology & Section on Statistical Genetics

Department of Biostatistics University of Alabama at Birmingham, Birmingham, Alabama

Jul 1999 – Dec 01: Assistant Professor Department of Epidemiology and Biostatistics Case Western Reserve University, Cleveland, Ohio Aug 1996 – Jun 1999: Senior Instructor Department of Epidemiology and Biostatistics Case Western Reserve University, Cleveland, Ohio Sep 1990 – Jun 1993: Assistant Professor of Mathematics and Computer

Science. University of Maine, Fort Kent, Maine.

Aug 1988 – Aug 1990: Visiting Assistant Professor of Mathematics. Loyola University of Chicago, Chicago, Illinois. Aug 1986 – May 1988: Visiting Assistant Professor of Mathematics. University of Notre Dame, Indiana. Summer 86: Instructor for Finite Mathematics for Upward bound program. University of Notre Dame, Indiana. Aug 1982 – May 1986: Graduate Teaching Assistant in Mathematics. University of Notre Dame, Indiana.

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Aug 1978 – Feb 1980: Research Fellow. Bhaskaracharya Prathisthana, Pune, India. AREAS OF RESEARCH INTEREST:

• Genetic Linkage and Association Analysis using SNPs and CNVs in family and Case-Control data

• Linkage Disequilibrium Mapping of population data, Admixture Mapping

• Structural Variation (SV)

• Pathway and Network analysis

• Population Genetics

• Molecular Evolution

• Next Generation Sequencing Methodology: Whole Genome Analysis,

Exome Sequencing Analysis, RNA-Seq Analysis

• Epigenetics/Epigenomics

• Pharmacogenetics

• Bioinformatics

• Metabolomics

• Microbiome and Metagenome

• Mitochondria and Nuclear Genome Interactions

• Genetics of Obesity and Diabetes, Rheumatoid Arthritis, SLE, Cardiovascular and Lung Diseases, Cancer, and Multiple Sclerosis.

PROFESSIONAL SOCIETIES: Member of the Genetic Society of America Member of the American Society of Human Genetics Member of the International Genetic Epidemiology Society

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Member of International Biometric Society Member of American Statistical Society UAB Centers Appointments: Sept 1, 2015 - : Comprehensive Arthritis, MSK, Bone and Autoimmunity Center June 19, 2014 - : Cystic Fibrosis Research Center March 1, 2012 - : Comprehensive Cancer Center November 8, 2010 - : Center for Cardiovascular Biology June 6, 2009 - : Center for Clinical And Translational Science Feb 12, 2009 - : Nutrition Obesity Research Center March 1, 2003 - : Comprehensive Diabetes Center HONOURS & AWARDS: 2010 Graduate Dean’s Excellence in Mentoring Award, School of Public Health, UAB 2009 Nominated for ASPH/Pfizer Teaching Excellence Award 2006 Best Paper award in Statistical Genetics by Science Upward Foundation Fellow at the University of Notre Dame in 81/82 academic year Council of Scientific and Industrial Research Fellowship from January 79 to February 80 Research Fellowship at Tata Institute of Fundamental Research at Bombay from May 79 to August 79 R. S. Srivastava Memorial Fellowship for 77/78 academic year PAPERS REVIEWED FOR THE FOLLOWING JOURNALS I have reviewed several manuscripts for wide variety of journals such as

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American Journal of Epidemiology, American Journal of Human Genetics, Annals of Applied Statistics, Annals of Human Genetics, Behavior Genetics, Biometrics, Bioinformatics, BMC Genetics, BMC Medical Genomics, Computational Statistics & Data Analysis, Diabetes, European Journal of Human Genetics, Genetic Epidemiology, Genetics, Genome Research, Genomics, Heredity, Human Heredity, Hypertension, Journal of American Statistical Association, Journal of Clinical Endocrinology and Metabolism, Neurochemical Research, Neuropsychopharmacology, Obesity, PLoS Genetics, PLoS Biology, Pharmacogenomics, Statistics in Medicine, Schizophrenia Bulletin.

NATIONAL PEER REVIEW BOARD June 23, 2016: ZRG1 BST-U(50) R03 Metabolomics review panel May 28, 2015: Short-Term Training to Promote Diversity in Health Research (R25) Special Emphasis Panel June 19-20, 2014: NIH BD2K Review: Education Resources (R25) and Career Development (K01) June 27, 2013: NHLBI review panel - NIH Research Education Grant Applications R25 applications Mar 7, 2013: Center for inherited disease research (CIDR) CAC Study Section Review Meeting April 26, 2013: Center for inherited disease research (CIDR) CAC Study Section Review Meeting April 26, 2013: Review of Kentucky Science and Engineering Foundation grants February 19-20, 2013: Special Emphasis Panel/Scientific Review Group 2013/05 ZCA1 RPRB-2 (M1) meeting Jan 10, 2013: Center for inherited disease research (CIDR) CAC Study Section Review Meeting Nov 12, 2012: NIH Fellowship Review Study Section, Review Meeting September 14, 2012: Center for inherited disease research (CIDR) CAC Study Section Review Meeting Aug 31, 2012: The Foundation for Science and Technology of Portugal (FCT) grant proposals

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March 8, 2012: Center for inherited disease research (CIDR) CAC Study Section Review Meeting Jan 13, 2012: Center for inherited disease research (CIDR) CAC Study Section Review Meeting Sept 9, 2011: Center for inherited disease research (CIDR) CAC Study Section Review Meeting July 15, 2011: Center for inherited disease research (CIDR) CAC Study Section Review Meeting March 11, 2011: Center for inherited disease research (CIDR) CAC Study Section Review Meeting January 07, 2011: Center for inherited disease research (CIDR) CAC Study Section Review Meeting December 10, 2010: NHLBI Ruth L Kirschstein Institutional National Research Service Award (T32) Reviews. November 12, 2010: Center for inherited disease research (CIDR) Review Meeting October 19-20, 2010: Review Group Subcommittee G – Education, NCI September 7-8, 2010: Center for inherited disease research (CIDR) Review Meeting May 25, 2010: Stage 1 Reviewer, NIH Director’s Opportunity for Research in Five Thematic Areas (RC4) RFA OD10-005. March 11-12, 2010: ZRG1 F16-G (20) L Fellowships: Healthcare Delivery and Methodologies Study Section. January 26, 2010: Review Group Subcommittee G – Education, NCI November 18 – 19, 2009: ZRG1 HOP F16-B 20 Special Emphasis Panel Healthcare Delivery and Methodologies Fellowship Study Section. November 3 - 4, 2009: Review Group Subcommittee G – Education, NCI June 30, 2009: Special Emphasis Panel/Scientific Review Group ZAG1 ZIJ-2 (O1) Study Section.

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May 07, 2009: Special Emphasis Panel/Scientific Review Group ZDE1 JH (24) Study Section. NIDCR. June 19 – 20, 2008: NHLBI Institutional Training Mechanism Review Committee. September 21, 2006: ZAG1 ZIJ-2 (J5), National Institutes on Aging Special Emphasis Panel, NIH. July 13 – 14, 2006: Chartered Member, Special Emphasis Panel (Member Conflict Reviews), NAME Study Section, Center for Scientific Review, National Institutes of Health. June 15 – 16, 2006: Chartered Member, NAME Study Section, Center for Scientific Review, National Institutes of Health. April 4, 2006: NIDCR R03 Review Study Section, Center for Scientific Review, National Institutes of Health. February 23 – 24, 2006: Chartered Member, NAME Study Section, Center for Scientific Review, National Institutes of Health. November 15 – 16, 2005: ZAG1 ZIJ-2 (J5), National Institutes on Aging Special Emphasis Panel, NIH. October 17 – 18, 2005: Chartered Member, NAME/ECDA Study Section, Center for Scientific Review, National Institutes of Health. June 23 – 24, 2005: Chartered Member, NAME/ECDA Study Section, Center for Scientific Review, National Institutes of Health. June 22, 2005: Special Emphasis Panel, ECDA/NAME Study Section, Center for Scientific Review, National Institutes of Health. February 23 – 25, 2005: Chartered Member, ECDA Study Section, Center for Scientific Review, National Institutes of Health. October 21 – 22, 2004: Chartered Member, ECDA Study Section, Center for Scientific Review, National Institutes of Health. June 24 – 25, 2004: Chartered Member, ECDA Study Section, Center for Scientific Review, National Institutes of Health. February 18 – 20, 2004: Chartered Member, ECDA Study Section, Center for Scientific Review, National Institutes of Health. October 23 – 24, 2003: Chartered Member, ECDA Study Section, Center for

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Scientific Review, National Institutes of Health. June 19 – 20, 2003: Chartered Member, ECDA Study Section, Center for Scientific Review, National Institutes of Health. February 20 – 21, 2003: Chartered Member, Special Emphasis Panel, Epidemiology and Disease Control-3 Study Section, Center for Scientific Review, National Institutes of Health. October 24 – 25, 2002: Ad Hoc Reviewer, Special Emphasis Panel, Epidemiology and Disease Control-3 Study Section, Center for Scientific Review, National Institutes of Health. June 13 – 14, 2002: Ad Hoc Reviewer, Special Emphasis Panel, Epidemiology and Disease Control-3 Study Section, Center for Scientific Review, National Institutes of Health. February 21 – 22, 2002: Ad Hoc Reviewer, Special Emphasis Panel, Epidemiology and Disease Control-3 Study Section, Center for Scientific Review, National Institutes of Health. October 24 – 25, 2001: Ad Hoc Reviewer, Special Emphasis Panel, Epidemiology and Disease Control-3 Study Section, Center for Scientific Review, National Institutes of Health. April 23, 2001: Ad Hoc Reviewer, Special Emphasis Panel, Centers for research to reduce oral Health Disparities, National Institute of Dental & Craniofacial Research March 8, 2001: Ad Hoc Reviewer, Special Emphasis Panel, National Institute of Heart, Lung and, Blood Institute. March 9, 2001: Ad Hoc Reviewer, Special Emphasis Panel, National Institute of Heart, Lung, and, Blood Institute. EDITORIAL BOARD Co-Chief Editor: Frontiers in Statistical Genetics and Methodology Associate Editor: Human Heredity Editorial Board Member: International journal of Medical Engineering and Informatics. Editorial Advisory Board Member: Behavior Genetics (Springer).

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Academic Editor: Plos Biology, 2007 SERVICE ACTIVITIES Departmental: 2015 – : Member of Departmental Faculty Affairs Committee 2015 – : Member of Search Committee for Biostatistics Assistant/ Associate Professors 2011 – : Director of Post-Doctoral Training Program in SSG: Responsibilities include recruitment, education, professional development, and evaluation of post-doctoral trainees. 2008 – 2017: Director of Pre-Doctoral Training Program in Biostatistics: Responsibilities include recruitment, education, professional development, and evaluation of pre-doctoral trainees. 2009 – 2011: Chair of the Biostatistics Admissions Committee: Role of the committee is to select new graduate students for a graduate program in biostatistics. 2009 – 2011: Member of the Graduate Program Committee: Role of the committee is to oversee the development of graduate program in biostatistics. 2009 – 2011: Member of the Pre-doctoral Students Recruitment Committee: Role of the committee is to develop and implement best recruitment strategies to recruit students in biostatistics program. 2007 – 2011: Chair of the SSG Recruiting Committee: Role of the committee is to recruit faculty in SSG. 2006 – 2009: Member of the Biostatistics Admissions Committee: Role of the committee is to select new graduate students for a graduate program in biostatistics. 2005 – 2011: Associate Director of Post-Doctoral Training Program in SSG: Responsibilities include recruitment, education, professional development, and evaluation of post-doctoral trainees. 2002 – 2005: Member of the SSG Recruiting Committee: Role of the committee was to recruit Post Doctoral fellows & Assistant Professors in SSG.

2002 – 2004: Member of the SSG Curriculum Committee: Role of the

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committee was to develop new courses in Statistical Genetics for a graduate program in biostatistics, in particular, developed syllabus for courses BST775 and BST776, which have been approved by EPC.

School of Public Health:

2016 – : Member of SOPH Faculty Affairs Committee 2011 – 2016: Member of the Diversity and Equity Committee: To recruit the most highly qualified and diverse faculty, students, and staff for open positions and/or admission at the UAB School of Public Health. Implement a set of activities that will allow the UAB School of Public Health to retain the most qualified diverse faculty, staff, and students. 2010 – 2014: Member of the search Committee for the Biostatistics Chair: Role of the committee is to recruit Chair for the Department of Biostatistics. 2010 – 2011: Chair of the Epidemiology Recruiting Committee: Role of the committee is to recruit faculty in Department of Epidemiology. 2009 – : Member Honor Court: Role of the committee was to review and deliberate on a student’s honor code violation resulting from plagiarism. 2007 – 2011: Member of Advisory Committee on Information Technology in School of Public Health: Role of the committee is to advise on informational technology needs for school of public health. University: 2016 – : School of Public Health Representatives on the University-wide Grievance Panel: Role of the committee is to resolve the grievances’ of faculty (if reported) and recommends a course of action to appropriate administrator. 2014 –2015: Member of Search Committee for Vice President of Information Technology and Chief Information Officer 2014 – : Member of Committee to develop “UAB Research Computing Strategic Plan” 2008 – 2011: School of Public Health Representatives on the University-wide Grievance Panel: Role of the committee is to resolve the grievances’ of faculty (if reported) and recommends a course of action to appropriate administrator. 2007 – 2009: Member of the Search Committee for the William and Joy

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Herbert Endowed Chair in Cancer Genetics: Role of the committee is to recruit internationally renowned cancer geneticist. 2007 – 2008: Member of the IGGP Admissions Committee: Role of the committee is to select new graduate students for an Interdisciplinary Genetics Graduate Program. 2006 – 2009: Member of the Interdisciplinary Genetics Graduate Program (IGGP) Curriculum Committee: Role of the committee is to develop new interdisciplinary courses in genetics for a graduate.

2002 – 2010: Director of SSG Seminar series. Organize monthly seminar series in statistical genetics, bioinformatics, biostatistics, and genomics. My role is to invite the speakers and help in making arrangements for their pleasant stay in Birmingham. The abstracts and videos of seminars are freely available on SSG web page:

http://www.soph.uab.edu/ssg/courses/ssgseminars National/ International: 2008 – 2014: Member of membership committee of International Genetic Epidemiology Society (IGES). Role of the committee is to develop a strategy to increase and retain the society membership. 2013 – : External Advisory Board Member on Centers of Biomedical Research Excellence (COBRE) program. The grant is entitled: “Mentoring Research Excellence in Aging and Regenerative Medicine.”

OTHER PROFESSIONAL ACTIVITIES Dec 12 – 15, 2016: Organized 5th NHGRI sponsored national short course on “Next-Generation Sequencing: Technology and Statistical Methods” at UAB. July 11 – 15, 2016: Organized 6th NIGMS sponsored national short course on “Statistical Genetics and Genomics” at UAB. Dec 14 – 17, 2015: Organized 5th NHGRI sponsored national short course on “Next-Generation Sequencing: Technology and Statistical Methods” at UAB. July 27 – 31, 2015: Organized 5th NIGMS sponsored national short course on “Statistical Genetics and Genomics” at UAB. Dec 15 – 18, 2014: Organized 4th NHGRI sponsored national short course on “Next-Generation Sequencing: Technology and Statistical Methods” at UAB. July 7 – 11, 2014: Organized 4th NIGMS sponsored national short course on

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“Statistical Genetics and Genomics” at UAB. Dec 16 – 19, 2013: Organized 3rd NHGRI sponsored national short course on “Next-Generation Sequencing: Technology and Statistical Methods” at UAB. July 8 – 12, 2013: Organized 3rd NIGMS sponsored national short course on “Statistical Genetics and Genomics” at UAB. Dec 10 – 13, 2012: Organized 2nd NHGRI sponsored national short course on “Next-Generation Sequencing: Technology and Statistical Methods” at UAB. July 9 – 13, 2012: Organized 2nd NIGMS sponsored national short course on “Statistical Genetics and Genomics” at UAB. Dec 13 – 16, 2011: Organized 1st NHGRI sponsored national short course on “Next-Generation Sequencing: Technology and Statistical Methods” at UAB. July 18 – 22, 2011: Organized 1st NIGMS sponsored national short course on “Statistical Genetics and Genomics” at UAB. August 3, 2009: Chaired a Session on "Continued Use of Family Data in Statistical Genetics", JSM, July 30 - 6, 2009. July 13 – 17, 2009: Co-organized Short Course in Statistical Genetics and Genomics at Hawaii funded by NSF. March 16, 2009: Chaired a Session on "Assessing Gene and Environment Interactions in Genome-Wide Studies", March 15-18, 2009. ENAR Meeting in San Antonio, TX Feb 12, 2009: Co-organized a Short Course in Statistical Genetics and Genomics at Southern Regional Conference in New Orleans. Nov 13, 2008: Moderator of Session on Statistical Genetics, American Society of Human Genetics Annual Meeting, Philadelphia, Pennsylvania. July 21 – 25, 2008: Co-organized First NSF Short Course in Statistical Genetics at UAB. May 7 – 8, 2008: Co-organized NHGRI sponsored conference on “Haplotype Analysis of Population and Pedigree Data in Association Analysis” at UAB. March 16 – 19, 2008: Co-organized NIDDK eighth Annual Short Course in Statistical Genetics for Obesity & Nutrition Researchers at San Diego. July 30, 2007: Chaired a Session on "Analysis of High-Dimentional Data-

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Contributed", JSM 2007 May 14 – 15, 2007: Co-organized NIDDK seventh Annual Short Course in Statistical Genetics for Obesity & Nutrition Researchers at San Diego. March 20 – 21, 2006: Co-organized PROGENI Conference on Admixture Mapping Methods & Software Demonstration at UAB. October 11, 2006, Moderator of Session on Obesity & Diabetes, American Society of Human Genetics Annual Meeting, New Orleans, Louisiana. March 30 – 31, 2006: Co-organized NIDDK Sixth Annual Short Course in Statistical Genetics for Obesity & Nutrition Researchers at San Francisco. March 6 – 7, 2006: Organized NIAMS Short Course: Frontiers in Statistical Genetics at Atlanta. December 2 – 4, 2005, Organizer & Chair of Session on Issues & Solutions in Statistical Genetics, 12th Annual international conference of the Forum for Interdisciplinary Mathematics, Auburn, AL. October 15 – 19, 2005, Chair of Session on Public Health/ Epidemiology/ Population Genetics: Genetics of Obesity, NAASO 2005 Annual Scientific Meeting, Vancouver, British Columbia, Canada. May 15 – 16, 2003, Center for Alaska Native Health Research, External Advisory Council Meeting, University of Alaska, Fairbanks, Alaska. December 2, 2002: Organized One-Day IMS sponsored Mini-conference on “Statistical Integration of Genetic Information across Data Domains: Biomedical, Agricultural, and Comparative Genomics”. The details of the conference and videos of each lecture presented are available on our section of statistical genetics home page: ADVISOR TO STUDENT ORGANIZATION Sep 1996 – May 1997: Racquet Ball Club at Case Western Reserve

University. Sep 1990 – May 1993: International Student Organization at University of

Maine. ACADEMIC ADVISOR Jan 2017 – Kristin Olson (Biostatistics Student) at UAB

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Jan 2016 – Michael Froelich (Biostatistics Student) at UAB Jan 2016 – Allison C Fialkowski (Biostatistics Student) at UAB Aug 2015 – Rajan K. Kharel (Biostatistics Student) at UAB Aug 2015 – Stephanie E Tison (Biostatistics Student) at UAB Aug 2014 – 2015 Xueyen Zhao (MSPH student) Aug 2013 – Dec 2015 Jessica Balena-Boreman (Biostatistics Student) at UAB August 2010 – May 2016 Lindsay Jones, (PhD Student in Biostat Dept.) Aug 2011 – Aug 2013 Nicole Rembert (Biostatistics Student) at UAB Aug 2009 – May 2011 Lindsey Hornung (Biostatistics Student) at UAB Aug 2007 – May 2011 Thomas Birkner (Biostatistics Student) at UAB May 2006 – Aug 2011 Nathan E Wineinger (Biostatistics Student) at UAB Aug 2005 – Dec 2007 Tarun Arora (Biostatistics Student) at UAB Aug 2004 – Aug 2006 Kathakali Ghosh (Biostatistics Student) at UAB Aug 2003 – July 2004 Xuemei Sui (MPH student) at UAB Sep 2000 – Dec 2001 Guohua Zhu (MS Student) at CWRU Sep 2000 – Dec 2001 Courtney McGuire (Ph.D. Student) at CWRU Jul 2001 – Dec 2001 Ron Blanton (MS Student) at CWRU RESEARCH MENTOR or Chair of Dissertation committee Jan 2017 – Kristin Olson Jan 2016 – Michael Froelich Jan 2016 – Allison C Fialkowski August 2014 – Vincent A Laufer (Co-mentor with Dr. Bridge

(Rheumatology))

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August 2012 – Dec 2015 Lindsay Jones, (PhD Student in Biostat Dept.) June 2014 – Aug 2014 Dayanara Lebrón-Aldea (Summer Intern) June 2013 – Aug 2013 Luis Miguel Mestre Caraballo (Summer Intern) Jan 2010 – July 2012 Dominick Limas (PhD Student Visitor from University

of Alaska at Fairbanks) co-mentor with Dr. Boyer June 2011 – Aug 2011 Kamil Sullivers (Summer Intern in Biostat Dept.) June 2009 – July 2009 Guillermo Rodriguez (Summer Intern) May 2006 – Aug 2011 Nathan E Wineinger (PhD Student in Biostat Dept.) May 2007 – July 2007 Ankur Moondan (Summer Intern in Biostat Dept.) Aug 2006 – Dec 2007 Tarun Arora (MS Student in Biostat Dept.) Jul 2001 – Dec 2001 Catherine Stein (Ph.D. Student Genetic Epi Dept, CWRU) PhD DISSERTATION/ MS THESIS COMMITTEE: 2016 – 2017 Seth Lirette (PhD Mentor: Dr. Aban) Department of Biostatistics,

School of Public Health, UAB 2015 – 2017 Elizabeth Y Scribner (PhD Mentor: Dr. Fathallah-Shaykh)

Department of Mathematics, School of Arts and Science, UAB 2016 – 2017 Anh Do (PhD Mentor: Dr. Irvin) Department of Epidemiology, School of Public Health, UAB 2014 – Vincent A Laufer (MD/PhD Mentor: Dr. Bridges) MSTP student, School of Medicine, UAB 2015 – 2016 Kwadwo Antwi-Fordjour (PhD Mentor: Dr. Mubenga Nikashama) Department of Mathematics, School of Arts and Science, UAB 2013 – 2015 Fatin S Alawam (PhD Mentor: Dr. Knowels) Department of Mathematics, School of Arts and Science, UAB 2012 –2014 Ngan Thanh Tran (MS Mentor: Dr. Arnett)

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Department of Epidemiology, School of Public Health, UAB 2012 – 2014 Terrence Muthoka (Ph.D. Mentor: Dr. Mubenga Nikashama) Department of Mathematics, School of Arts and Science, UAB 2011 – 2015 Himel Mallick (PhD Mentor: Dr. Yi) Department of Biostatistics, School of Public Health, UAB 2010 – 2014 Brandon George (PhD Mentor: Dr. Aban) Department of Biostatistics, School of Public Health, UAB 2012 – 2014 Qi Yan (PhD Mentor: Dr. Liu) Department of Biostatistics, School of Public Health, UAB 2011 – 2014 Guodong Wu (Ph.D. Mentor: Dr. Aban) Department of Biostatistics, School of Public Health, UAB 2010 – 2013 Staci Sudenga (Ph.D. Mentor: Dr. Shrestha) Department of Epidemiology, School of Public Health, UAB 2010 – 2012 Mawuli Kwa Nyaku (Ph.D. Mentor: Dr. Shrestha) Department of Epidemiology, School of Public Health, UAB 2010 – 2011 Thomas Birkner (Ph.D. Mentor: Dr. Aban) Department of Biostatistics, School of Public Health, UAB 2009 –2010 Peter Merrill (MS. Mentor: Dr. McClure) Department of Biostatistics, School of Public Health, UAB 2007 – 2008 Renee Pasker (MS. Mentor: Dr. Boyer) University of Alaska at Fairbanks, Fairbanks, Alaska 2005 – 2008 Samprit Banerji (Ph.D. Mentor: Dr. Yi) Department of Biostatistics, School of Public Health, UAB 2006 – 2008 Andres Azuero (Ph.D. Mentor: Dr. Redden) Department of Biostatistics, School of Public Health, UAB 2006 – 2008 Marguerite R Dickson (Ph.D. Mentor: Dr. Go) Department of Epidemiology, School of Public Health, UAB 2007 – 2008 Torey Combs (MS. Mentor: Dr. Nagy) Department of Pathology, UAB 2007 – 2007 Dahliann A Morrison (PhD Mentor: Dr. Bridges)

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Division of Clinical Immunology & Rheumatology, SOM, UAB 2006 – 2008 Zhiying You (Ph.D. Mentor: Dr. Cutter) Department of Biostatistics, School of Public Health, UAB 2006 – 2008 Justin T Arcury (MS. Mentor: Dr. Beasley) Department of Biostatistics, School of Public Health, UAB 2004 – 2006 Marshall Scott (MS. Mentor: Dr. Redden) Department of Biostatistics, School of Public Health, UAB 2004 – 2006 Kathakali Ghosh (MS. Mentor: Dr. Aban) Department of Biostatistics, School of Public Health, UAB 2003 – 2006 Jian Li (Ph.D. Mentor: Dr. Rodney) Department of Epidemiology, School of Public Health, UAB 2001 Lee-Lian Kim (Ph.D. Mentor: Dr. Witte) Genetic Epidemiology, CWRU, Cleveland. 2001 Shaoqi Rao (MS Mentor: Dr. Olson) Genetic Epidemiology, CWRU, Cleveland. 2001 Sarah Buxbaum (Ph.D. Mentor: Dr. Elston) Genetic Epidemiology, CWRU, Cleveland. 2001 Kijjoung Song (Ph.D. Mentor: Dr. Elston) Genetic Epidemiology, CWRU, Cleveland. 2001 Belhassen Kaabi (Ph.D. Mentor: Dr. Elston) Genetic Epidemiology, CWRU, Cleveland. 2000 Jedidiah R. Gass (M.S.D. Mentor: Dr. Valiathan) Department of Orthodontics, CWRU, Cleveland. 1996 Michael Labranche (Ph.D. Mentor: Dr. Elston) Genetic Epidemiology, LSU, New Orleans.

POST DOCTORAL FELLOWS Primary Mentor: April 2017 – Current Rafet Al-Tobasei, Ph.D. April 2012 – Jan 2015 Michael Sandel, Ph.D.

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Mar 2012 – Sept 2014 Bertha Hidalgo, Ph.D. Aug 2011 – Jul 2014 Curtis Holliman, Ph.D. Aug 2009 – Aug 2010 Kofi Adragni, Ph.D. Mar 2008 – April 2011 Richard Kennedy, Ph.D. Aug 2005 – Jun 2008 Miguel Padilla, Ph.D. Oct 2003 – Oct 2005 Solomon Musani, Ph.D. Co-Mentor: Sept 2017 – Anarina Le Murillo, PhD Sept 2015 – Jan 2017 Noha Sharafeldin, MD/PhD Aug 2009 – April 2011 Margurite Ryan Irvin, Ph.D. Aug 2006 – July 2009 Stephen Ericson, Ph.D. April 2005 – July 2008 Laura Kelly Vaughn, Ph.D. Aug 2005 – Oct 2007 Tesfaye Mersha, Ph.D. PRESENTATIONS July 15, 2016: Lectures on “Integration of different data domains in silico for causal inference: Challenges and Issues” in NIGMS funded Short Course on Statistical Genetics and Genomics July 11, 2016: Lectures on “Introduction to Statistical Genetics” in NIGMS funded Short Course on Statistical Genetics and Genomics June 17, 2016: Lecture on “Genetic models in Obesity: Classic and Modern” in Short Course on The Mathematical Sciences in Obesity July 23, 2015: Lecture on “Methodological issues in Testing for Gene by Environment or Gene by Behavior Interactions” in 1st Short Course on Strengthening Causal Inference in Behavioral Obesity Research. June 26, 2015: Lecture on “Genetic association analysis of 30 genes related to

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obesity in a European American population: an overview” in Short Course on The Mathematical Sciences in Obesity May 25, 2015: Lecture on “Statistical issues in DNA methylation analysis and potential solutions” at Wake Forest University, Wake Forest, NC April 23, 2015: Poster presentation on “Biomarker and relapse in CombiRx” at AAN conference in Washington, DC April 7, 2015: Invited talk on “Transgenerational inheritance of methylation” on honor of Dr. Robert C. Elston at the Case Western University, Cleveland March 31, 2015: Invited talk on “Issues and challenges to analyze genome-wide methylation data and possible solutions” at the University of Pennsylvania, Philadelphia. July 8, 2014: Lectures on “Design, Analysis, and interpretation of GWAS” and “X-Chromosome, Imputation to 1000 Genomes” in NIGMS Short Course on Statistical Genetics and Genomics May 16, 2014: Invited presentation on “Genetic Association Analysis of 30 Genes Related to Obesity in a European American Population: Overview” in a Mathematical Sciences in Obesity Research Short Course at UAB March 17, 2014: Invited presentation on “Is Post-Doc Fellowship Key to Academic Success” for Council for Emerging New Statisticians Invited Session: Should I do a Post-Doc? at the ENAR conference, Washington, DC March 17, 2014: Invited presentation on “Is Post-Doc Fellowship Key to Academic Success” for Council for Emerging New Statisticians Invited Session: Should I do a Post-Doc? at the ENAR conference, Washington, DC March 7, 2014: Invited presentation on “Challenges and Issues in Analyzing Different Genomic and Proteomic Data” at the conference on “Ordered Data Analysis, Models and Health Research Methods: An International Conference in honor of H. N. Nagaraja for his 60th Birthday” at University of Texas at Dallas, Dallas, TX July 9, 2013: Lectures on “Non-Mendelian Diseases” in NIGMS funded Short Course on Statistical Genetics and Genomics Oct 7, 2011: Invited presentation on “Detecting genes for complex traits through new genomic technology” at the department, Information Systems, Statistics & Management Science, University of Alabama, Tuscaloosa, AL.

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April 14, 2011: Invited presentation on “Finding genes for complex diseases/traits: Are we there yet?” at the Department of Biostatistics, University of Georgia, Athens, GA. March 30, 2010: Invited presentation on “Statistical methods for high dimensional genomic data” at Spring Scientific Symposium, HudsonAlpha Institute of Biotechnology. Aug 12, 2009: Oral presentation on “Genetic Association Testing in Pedigree Data” in SSG Retreat, Birmingham. Aug 4, 2009: Invited presentation on “Pre- and Post GWAS” to Diabetes Institute in Madras, India through video conference. June 17, 2009: Oral Presentation on “Efficient procedure to analyze pedigree data with mixed model” in Progini and GOLDN conference, Baltimore, MD. April 27, 2009: Invited presentation on “Genetic Association Testing in Pedigree data: Issues and solutions” Department of Genetics, UCLA, CA. Mar 16, 2009: Oral presentation on “Within-Cluster Resampling (Multiple Outputation) for Analysis of Family Data: Ready for Prime-Time?” ENAR 2009, San Antonio. Nov 12, 2008: Poster presentation on “Accurate and Flexible Power Calculations in genetics” in American Society of Human Genetics meeting, Philadelphia, PA. Oct 24, 2008: Gave an Invited presentation on “Accurate and Flexible Power Calculations on the spot: Application to Genomic Research”, in Quantitative Genomics Seminar series at the Division of Human Genetics at Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH. Oct 23, 2008: Gave an Invited presentation on “Introduction to New Genetics/ Genomics”, at the Epidemiology and Biostatistics Department, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, OH May 18, 2008: Gave an Invited presentation on “Resampling Methods to Analyze Genome-Wide Family Data”, in International Conference on Interdisciplinary Mathematical & Statistical Techniques, at The University of Memphis, Memphis. March 16, 2008: Poster presentation on “Multiple Imputation for Family-Based Association Studies” in ENAR meeting, Crystal City, VA. March 10, 2008: Gave a presentation on “LDDAC and GWA-Test Driver” at Workshop-Heflin Center for Analytic and Epidemiologic Genomics (CAEG).

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February 6, 2008: Gave an oral presentation on “Within-Cluster Resampling-Multiple Outputation for Analysis of Family Data- Ready for Prime Time?” at The eighth annual quantitative genetics symposium, MD Anderson, Huston, TX. June 13, 2007: Gave an Invited presentation on “Comparison of General Extensible Models for Analyzing Data from Related Individuals”, NIA Workshop on Statistical Methods for Logitudinal Data on Aging at National Institute of Aging, Bethesda, MD. May 15, 2007: Gave an Invited presentation on “Haplotype Inference”, at seventh NIDDK sponsored short course for obesity and Nutrition researchers at Houston. Oct 23, 2006: Gave an Invited presentation on “Genome-Wide Association (GWA) studies, missing data, and multistage design” at the Department of Genetics, Boston University, Boston, MA. August 9, 2006: Gave a presentation on “Comparative Validity and Power of Methods for Association-Testing with Related Individuals” at Joint Statistical Meeting, Seattle, WA. May 18, 2006: Gave a seminar on “Issues & Challenges in genome-wide association studies for complex disorder” at the Department of Pathology, University of Alabama at Birmingham, Birmingham, AL. Feb 22, 2006: Gave a presentation on “Missing data methods for familial genetic data and association analysis using WCR” at the Department of Biostatistics, University of Maryland, Baltimore, MD. Jan 09, 2006: Gave a seminar on “Issues & Challenges in complex disorder and potential solutions” at the Department of Pathology, University of Alabama at Birmingham, Birmingham, AL. Oct 16, 2005: Gave an invited presentation on “Heritability analysis of obesity related traits in Alaskan Yup’ik Eskimos” at NAASO’s 2005 Annual Scientific Meeting, Vancouver, British Columbia, CA. Aug 7, 2005: Gave an invited presentation on “Incorporating Missing data methods for familial genetic data” at Joint Statistical Meeting, Minneapolis, MN. April 21, 2005: Gave an oral presentation on “Missing Data: Problems and potential Solutions” at The sixth annual quantitative genetics symposium, UAB, Birmingham. March 23, 2005: Gave an invited presentation on “Joint Tests for Association & Linkage for Quantitative Traits for random and non-random sampling” at Case Western Reserve University, Cleveland.

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April 1, 2005: Gave an invited presentation on “Issues & Challenges in Genetic Analysis of Complex Disorders” at University of Mississippi, Oxford, MS. Aug 11, 2004: Gave an invited presentation on “New Joint Covariance- and Marginal-based Tests for Association & Linkage for Quantitative Traits for random and non-random sampling: Power & Cost Analysis” at Joint Statistical Meeting, Toronto. June 14, 2004: Gave an oral presentation on “Single-step Hierarchical linear models vs. Multiple imputation for longitudinal data."” at Analysis Workshop for progeny network (NHLBI GxE Interaction Studies), Johns Hopkins University, Baltimore, MD. Mar 11, 2004: Gave an oral presentation on “New Joint Covariance- and Marginal-based Tests for Association & Linkage for Quantitative Traits for random and non-random sampling” at The fifth annual quantitative genetics symposium, UAB, Birmingham. Jan 27, 2003: Gave an oral presentation on “The A Class of Combined Covariance-Based and Marginal-Based Transmission Disequilibrium Tests for Quantitative Trait Loci for Human Data” at The fourth annual quantitative genetics symposium, MD Anderson, TX. Oct 12, 2003: Poster presentation on “ Distributional properties of a composite measure of adiposity” at NAASO’S 2003 Annual Meeting, Ft. Lauderdale, FL. Nov 16, 2002: Poster presentation at 11th annual meeting of the International Genetic Epidemiology Society at New Orleans, LA. Mar 22, 2002: Invited seminar on “Essentials of Bioinformatics for the Healthcare Professional” at 60th Annual Meeting of Association of Teachers of Preventive Medicine, Washington. Feb 15, 2002: Gave an oral presentation on “Sequential Testing of Association and Linkage for Quantitative Traits using Pedigree Data” at Department of Biostatistics, UAB, Birmingham. Nov 14, 2001: Gave an oral presentation “A general framework for comparing the power of mean effects and variance-component linear models for quantitative group comparisons” at Department of Epidemiology and Biostatistics, CWRU, Cleveland. Oct 17, 2001: Gave an oral presentation “Sequential testing using Transmission/ Disequilibrium Tests for Quantitative Traits” at Department of Epidemiology and Biostatistics, CWRU, Cleveland.

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Sept 17, 2001: Gave an oral presentation “Comparison of Mean Effects & Variance Components Models for Quantitative Traits” at Department of Biostatistics, University of Alabama, Birmingham, AL. July 23, 2001: Gave an oral presentation “Transmission/ Disequilibrium Tests for Quantitative Traits” at Department of Epidemiology, University of Minnesota, Minneapolis, MN. Oct 27, 2000: Poster presentation at ninth annual meeting of the International Genetic Epidemiology Society at San Antonio, TX. Oct 7, 2000: Poster presentation at eighth annual meeting of the American society of Human Genetics at Philadelphia, PA. Mar 10, 2000: Gave an oral presentation “Phylogeny Reconstruction of sequences that allow mutation and recombination simultaneously” at Genset Corporation, La Jolla, CA. Feb 23, 2000: Gave an oral presentation “Phylogeny Reconstruction: An Overview” at Case Western Reserve University, Cleveland. Oct 22, 1999: Poster presentation at eighth annual meeting of the American society of Human Genetics at San Francisco, California. Sep 10, 1999: Poster presentation at eighth annual meeting of the International Genetic Epidemiology Society at St. Louis, Missouri. Feb 4, 1999: Gave an oral presentation “Variance Component modeling in Human Genetics” at Medical College of Wisconsin, Milwaukee. Nov 2, 1998: Gave an oral presentation “Molecular Evolution” to the clinicians at Metro Health Medical Center for CME credit. Sep 11, 1998: Poster presentation at seventh annual meeting of the International Genetic Epidemiology Society at Arcachon, France. Jul 13, 1998: Gave an oral presentation on “Family-Based Candidate Locus Analysis of Quantitative Traits” at Mayo Clinic, Rochester, MN. Apr 24, 1998: Gave an oral presentation on “Variance Components Modeling” at the National Center for Human Genome Research, Bethesda, MD on. Oct 30, 1997: Poster presentation at sixth annual meeting of the American society of Human Genetics at Baltimore, Maryland.

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Oct 29, 1996: Gave an oral presentation on “Multilocus extension to H-E regression method” in Genetics Analysis Workshop 10, San Jose, CA. May 16, 1990: Gave an oral presentation on “Representation Theory of Hecke Algebras” at Central Arkansas State University, Conway, Arkansas. May 19, 1989: Speaker at AMS conference on the Algebraic Groups and related topics. Oct 27, 1988: Speaker at University of Chicago on Reflection Representation of Hecke Algebras. Feb 7, 1988: Speaker at Indian Institute of Technology on the Reflection Representation of Hecke Algebras of certain Weyl Groups, Kanpur, India. Have presented several seminars and participated in Journal Club on the various topics on mathematics, computer science, and genetic epidemiology at the University of Alabama, Case Western Reserve University, LSU Medical School, University of Maine at Fort Kent, Loyola University of Chicago, and University of Notre Dame. TEACHING ACTIVITY RELATED to STATISTICAL GENETICS, GENETIC EPIDEMIOLOGY, POPULATION GENETICS, and BIOINFORMATICS: Fall, 2017: BST795: Population Genetics and Molecular Evolution. Spring, 2016: BST632: Statistical Theory II. Mar 2, 2016: Lecture on “Genetic Linkage Analysis” in GBS787 October 16, 2015: Lecture on “Genetic Linkage Analysis” in Immersion Course

organized by Dr. Bruce Korf. October 16, 2015: Lecture on “Genome-Wide Association Analysis” in

Immersion Course organized by Dr. Bruce Korf. Fall, 2015: BST631: Statistical Theory I. April 16, 2015: Lecture on “Mendelian Randomization” in BST 675 class. Jan 12, 2015: Lecture on “Genetic Linkage Analysis” in Immersion Course at UAB October, 2014: Lectures on “Discussion on NIH R25s and R13s” in SSG

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Grant Club meeting Fall 14: BST631: Statistical Theory I. June 26-27, 2014: Two Presentations on “Introduction to Statistical Genetics”

for Summer Interns in SSG April 4, 2014: Gave a lecture in SSG Journal Club on “Challenges and

Issues in Analyzing and Integrating Genomic and Proteomic Data”

Feb 14, 2014: Gave a lecture in SSG Grant Club on “NIH T32 training grant

application” Feb 3, 2014: Two lectures in GBS 722-Bioinformatics on (1) Linkage

Analysis and (2) Association Analysis Jan 24, Feb 27, and April 9, 2014: Three lectures on Non-Mendelian Diseases:

(1) Multifactorial Diseases; (2) X-linkage Imputation and Association; and (3) Mitochondria Association in BST 776

Fall 13: BST631: Statistical Theory I. Fall 12: BST631: Statistical Theory I. Fall 11: BST631: Statistical Theory I. Fall 10: BST631: Statistical Theory I. Summer 10: Reading course (BST 695) with three Biostatistics students

on Imputation methods in Missing Data. April 9, 10: Taught in “Genetics of Chronic Inflammatory Diseases in

CMB 779 (Director: Jianming Wu)” Role: Two lectures on Overview of Statistical Methods in Genetics

Dec 1, 09: Gave a lecture on “Overview of Genetic Epidemiology &

Statistics Genetics” in BST600 (Course Director: George Howard)

Fall 09: BST776: Statistical Methods for Genetic Analysis II. Fall 08: BST775: Statistical Methods for Genetic Analysis I. July 22, 08: Gave a presentation on “Genome-wide association analysis

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using PLINK”, in first annual NSF sponsored short course on statistical genetics and statistical genomics.

June 23, 08: Gave a presentation on “Imputation Methods for Missing

Genetic Data” in Methodology Workshop for MCRC April 16, 08: Taught in “Howard Hugh Fellows (Directors: Dimmit, and

Tiwari)” Role: Lecture on Overview of Genetic Epidemiology pertaining to Rheumatoid Arthritis.

April 4, 08: Gave a presentation on “Family-Based Association and

TDT”, at eighth NIDDK sponsored short course for obesity and Nutrition researchers at San Diego.

Mar 4-25, 08: Gave 4 lectures in BST 726, Advanced Clinical Trial II on

Missing Data. May 15, 07: Gave a presentation on “Haplotype Inference”, at seventh

NIDDK sponsored short course for obesity and Nutrition researchers at Houston.

April 13, 07: Taught in “Genetics of Chronic Inflammatory Diseases in

CMB VII Module 4 (Directors: Lou Bridges & Laura Hugh)” Role: Two lectures on Overview of Statistical Methods in Genetics

Jan 24, 07: Taught in “Howard Hugh Fellows (Directors: Allison, Dimmit,

and Tiwari)” Role: Lecture on Overview of Statistical Methods in Genetics

Spring 07: Taught BST776: Statistical Methods for Genetic Analysis II. April 07, 06: Taught “Genetics of Chronic Inflammatory Diseases in CMB

VII Module 4 (Directors: Lou Bridges & Laura Hugh) Role: Lecture on Overview of Statistical Methods in Genetics

Fall 06: Taught BST775: Statistical Methods for Genetic Analysis I. May 5, 05: Taught a class in Dr. Bullard’s class MGE702 on Mendelian

Classic Linkage in Humans. Spring 05: Taught BST776: Statistical Methods for Genetic Analysis II. April 13, 05: Taught two lectures in Dr. Ruden’s class IBS 702 (III) on

Multi-factorial Diseases.

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Fall 04: Taught BST775: Statistical Methods for Genetic Analysis I. Spring 04: Co-Taught Reading Course BST698 to two MPH students

(Survival Analysis, Longitudinal Data Analysis) with Dr. Howard.

April 14, 04: Taught two lectures in Dr. Ruden’s class IBS 702 (III) on

Multi-factorial Diseases. Feb 26, 03: Taught one lecture on Association & Linkage Analysis in

BST 675 (Dr. Fernandez class) at University of Alabama at Birmingham.

Feb 8, 03: Taught 30 minute lecture on Family Based Haplotype

Analysis in a short course on statistical Genetics for Obesity & Nutritional Researchers at UAB.

Feb 9, 03: Organized and demonstrated the software used in Statistical

Genetics in a short course on statistical Genetics for Obesity & Nutritional Researchers at UAB.

Fall 01: Taught Statistics I, EPBI 431 at CWRU, Cleveland. Fall 00: Taught Biological Sequence Analysis and Molecular

Evolution, EPBI 472 at CWRU, Cleveland. Spring 99: Taught the course Population Genetics, EPBI-454 at CWRU,

Cleveland. Spring 98: Team taught the course in Population Genetics, EPBI-454

with Dr. Schork at CWRU, Cleveland. Fall 97: Taught three lectures on the topic “Delta Paths” in the

course EPBI-472 at CWRU, Cleveland. Spring 97: Taught two lectures on the topic “Evolutionary Change in

Nucleotide Sequences” in the course EPBI-454 at CWRU, Cleveland.

Spring 97: Taught five lectures on the topic “Multipoint Linkage

Analysis” in the course EPBI-457 at CWRU, Cleveland. Fall 96: Taught ten lectures on the topic “Path Analysis” in the

course EPBI-472 at CWRU, Cleveland.

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Spring 96: Taught eight lectures on the topic “Multipoint Linkage Analysis” in the course EPBI-457 at CWRU, Cleveland.

Fall 94: Taught six lectures on the topic “Multipoint Linkage Analysis”

in the course “Genetic Linkage Analysis” at LSU Medical Center, New Orleans.

Have taught several courses in mathematics, statistics, and computer science from 1982 to 1993 at several institutions: Notre Dame, Loyola, and the University of Maine.

RESEARCH SUPPORT ACTIVE NIH R01DK104347 (Boyer, Tiwari and Absher (multi-PIs)) 09/20/16 – 07/31/20 NIH/NIDDK $84,975 current direct Epigenome modification by a dietary pattern rich in polyunsaturated fatty acids

The overall goal of the proposed research is to identify epigenetic factors underlying the relationship between metabolic health and the traditional Yup’ik Alaska Native diet, rich in n-3 polyunsaturated fatty acids (PUFAs) from marine mammals, fish, and other wild country (subsistence) foods. Role: MPI NIH R01DK112358-01 (Boyer, Tiwari and Absher (multi-PIs)) 07/15/17 – 03/31/21 NIH/NIDDK $208,983 current direct Epigenome modification by a dietary pattern rich in polyunsaturated fatty acids

The increased prevalence of Type 2 Diabetes is a global health concern that has led to substantial increases in health care costs and increased morbidity and mortality. The proposed research is aimed at identifying diet-induced changes in genomic DNA methylation patterns that are associated with changes in downstream gene expression, as well as phenotypic and metabolic profiles associated with insulin sensitivity and protection from Type 2 Diabetes. Evaluation of the epigenomic impact of a protective dietary exposure may enhance our understanding of the molecular mechanisms underlying metabolic health, and the role that epigenetic factors play in mediating these relationships. Role: MPI NIH R25 GM093044 (Tiwari) 08/01/10 – 05/31/18 NIH/NIGMS No Cost Extension Short Course on Statistical Genetics and Genomics

To offer an annual statistical genetics short course to be focused on applying advanced quantitative approaches to the search for genes that predispose

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complex human disorders and quantitative traits. Role: Principal investigator NIH R25HG006110 (Tiwari) 04/01/11 – 01/31/17 NIH/NHGRI $ 49,968 current direct Short Course on Next-Generation Sequencing Technology and Statistical Methods

To offer an annual short course focused on technological and statistical approaches pertaining to next-generation sequencing applied to complex human disorders and quantitative traits. Role: Principal investigator NIH R01AR064820 (Brown) 07/01/14 – 06/30/19 NIH/NIAMS $491,709 current direct Association of genetic and autoantibody signatures with SLE clinical course The purpose of this study is to characterize complex interactions between variation in DNA sequence and autoantibody profiles with the rate of progression and severity of lupus-associated nephritis and severe organ damage, which are more common among ethnic minorities. The knowledge gained from this study may help us to lower the risk of lupus-related clinical manifestations and to manage and treat it more effectively. Role: Co-Investigator R01HL104135-04 (Arnett) 08/15/10-05/31/17 NIH/NHLBI $1,112,755 current direct Epigenetic Determinants of Lipid Response to Dietary Fat and Fenofibrate

This study aims to discover the epigenetic factors that cause people’s bodies to respond so differently to diet and drugs with the belief that such knowledge could ultimately help lower people’s risk for cardiovascular disease. Role: Co-investigator R01CA178441 (Tollefsbol) 04/01/2014 – 02/28/2019 NIH/NCI $202,807 current direct Combinatorial Epigenetic-Based Prevention of Breast Cancer Breast cancer is a significant health problem worldwide and is a leading cause of cancer morbidity and mortality. The overall goal of this application is to develop a combinatorial dietary approach consisting of green tea polyphenols and sulforaphane-rich broccoli sprouts for efficacious and safe use in preventing the epigenetic aberrations of breast cancer. Role: Co-investigator 1R01CA204346 (Tollefsbol) 01/01/2017-12/31/2021 NIH/NCI $228,750 current direct Early Life Prevention of Breast Cancer with Combined Epigenetic Botanicals Estrogen receptor-negative breast cancer is a leading cause of cancer morbidity

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and mortality because few treatment options exist for this often fatal disease. The goal of this application is to develop efficacious dietary regimens of epigenetic aberration-neutralizing dietary botanicals consumed at various stages of life for preventing estrogen receptor-negative breast cancer. Role: Co-Investigator 2R01HL091357-05 (Arnett) 08/01/2015 – 07/31/2019 NIH/NHLBI $649,961 current direct Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat This study aims to identify genetic variants that influence fat and cholesterol’s response to diet and drugs; this knowledge may someday help doctors tailor prevention efforts and treatments based on individual’s genetic endowment. Role: Co-investigator R01HL129907 (Ambalavanan) 09/15/2015 – 06/30/2018 NIH/NHLBI $250,000 current direct STOP BPD Bronchopulmonary dysplasia (BPD) is a common respiratory disorder in very preterm infants, characterized by impaired lung development, and associated with long-term respiratory complications. In this study, we will evaluate 300 extremely preterm infants to determine alterations in gene expression, protein amounts, or microbial flora in the airway that are associated with resilience (resistance to development of severe BPD, even when considered to be at high risk due to clinical risk factors) or predisposition (higher rate of developing severe BPD even if not initially considered at high risk). Role: Co-investigator R01HL092173 (Limdi) 08/01/2015 – 07/31/2019 NIH/NHLBI $499,667 current direct Genetic and Clinical Predictors of Response to Warafin and Novel Anticagulants Understanding clinical and genetic factors that predict patient specific risk of hemorrhage can help identify patients who stand to benefit or be harmed by oral anticoagulants drugs. The integration of these clinical and genetic predictors into the current treatment approach can help provide personalized treatment, improving outcomes for the individual patient. The increasing burden of atrial fibrillation in the US and the world, highlight the immense potential of such research in facilitating the realization of tangible individual and population health benefits. Role: Co-investigator 1R01 HL123782-01A (Irvin) 09/15/2016-05/31/2021

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NIH/NHLBI $499,791 current direct Genomic Background of Blood Pressure Response to Thiazide Diuretic in African Americans. Research shows that better blood pressure control produces cardiovascular benefits in African Americans. This study seeks to discover genetic variants that influence how blood pressure can be controlled in African Americans on a frequently used medication class (thiazide diuretics). In the future, such knowledge could help improve the care of African Americans with high blood pressure. Role: Co-Investigator 7R01 HL055679-19 (Arnett) 01/01/2016-04/30/2018 NIH/NHLBI $5,459,306 current direct HyperGEN: Genetics of Left Ventricular Hypertrophy Black people tend to have an enlarged left ventricle (the heart chamber that pumps oxygenated blood throughout the body) more commonly than those in other race groups, putting them at greater risk for having potentially fatal cardiovascular diseases. Enlarged left ventricles are caused, at least in part, by a person's genes. This study seeks to discover which genetic factors may cause an enlarged heart; this may ultimately lead to new diagnoses and treatments to help lower cardiovascular disease risk in blacks. Role: Co-Investigator Peer Review Publications: 1. Mohanty SP, Tiwari HK (1979): Powers of Sums of Digits. Mathematics Magazine 52:310-312. 2. Tiwari HK (1989): On the Reflection Representations of the Hecke Algebras of Certain Weyl Groups. Journal of Algebra 120: 224 - 245. 3. Knight A, Batzer MA, Stoneking M, Tiwari HK, Scheer WD, Herrera RJ, Deininger PL. DNA sequences of Alu elements indicate a recent replacement of the human autosomal genetic complement. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4360-4. PubMed PMID: 8633071; PubMed Central PMCID: PMC39542. 4. Tiwari HK, Elston RC. Deriving components of genetic variance for multilocus models. Genet Epidemiol. 1997;14(6):1131-6. PubMed PMID: 9433636. 5. Tiwari HK, Elston RC. Linkage of multilocus components of variance to polymorphic markers. Ann Hum Genet. 1997 May;61(Pt 3):253-61. PubMed PMID: 9250354.

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6. Tiwari HK, Elston RC. Restrictions on components of variance for epistatic models. Theor Popul Biol. 1998 Oct;54(2):161-74. PubMed PMID: 9733657. 7. Tiwari HK, Elston RC (1999): The Approximate Variance of a Function of Random Variables. Biometrical Journal 41: 351-357. doi:10.1002/(sici)1521-4036(199906)41:3<351::aid-bimj351>3.0.co;2-u 8. George V, Tiwari HK, Zhu X, Elston RC. A test of transmission/disequilibrium for quantitative traits in pedigree data, by multiple regression. Am J Hum Genet. 1999 Jul;65(1):236-45. Erratum in: Am J Hum Genet 1999 Oct;65(4):1214. PubMed PMID: 10364537; PubMed Central PMCID: PMC1378095. 9. George V, Tiwari HK, Shu Y, Zhu X, Elston RC. Linkage and association analyses of alcoholism using a regression-based transmission/disequilibrium test. Genet Epidemiol. 1999;17 Suppl 1:S157-61. PubMed PMID: 10597429. 10. Tiwari HK, Zhu X, Elston RC, Shu Y, George V. Association and linkage analysis of ICD-10 diagnosis for alcoholism. Genet Epidemiol. 1999;17 Suppl 1:S343-7. PubMed PMID: 10597460.. 11. Shete S, Tiwari H, Elston RC. On estimating the heterozygosity and polymorphism information content value. Theor Popul Biol. 2000 May;57(3):265-71. PubMed PMID: 10828218. 12. Jedrey CM, Chen CH, Moser KL, Wedig GC, George V, Tiwari HK. Transmission/disequilibrium test analysis of total serum IgE levels in the Hutterite and Collaborative Study on the Genetics of Asthma data sets. Genet Epidemiol. 2001;21 Suppl 1:S298-302. PubMed PMID: 11793686. 13. Hall MA, Norman PJ, Thiel B, Tiwari H, Peiffer A, Vaughan RW, Prescott S, Leppert M, Schork NJ, Lanchbury JS. Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 control variation in levels of T and B lymphocyte subpopulations. Am J Hum Genet. 2002 May;70(5):1172-82. Epub 2002 Apr 9. Erratum in: Am J Hum Genet 2002 Sep;71(3):693. PubMed PMID: 11951176; PubMed Central PMCID: PMC447593. 14. Valiathan M, Tiwari HK, Elston RC, Hans MB (2002): Genetic epidemiology: dental phenotypes in focus. Craniofacial Growth Series. , Vol 39: 237-255. 15. Gass JR, Valiathan M, Tiwari HK, Hans MG, Elston RC. Familial correlations and heritability of maxillary midline diastema. Am J Orthod Dentofacial Orthop. 2003 Jan;123(1):35-9. PubMed PMID: 12532061. 16. Thiel BA, Chakravarti A, Cooper RS, Luke A, Lewis S, Lynn A, Tiwari H, Schork NJ, Weder AB. A genome-wide linkage analysis investigating the

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determinants of blood pressure in whites and African Americans. Am J Hypertens. 2003 Feb;16(2):151-3. PubMed PMID: 12559684. 17. Fullerton J, Cubin M, Tiwari H, Wang C, Bomhra A, Davidson S, Miller S, Fairburn C, Goodwin G, Neale MC, Fiddy S, Mott R, Allison DB, Flint J. Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative-trait loci that influence variation in the human personality trait neuroticism. Am J Hum Genet. 2003 Apr;72(4):879-90. Epub 2003 Feb 20. PubMed PMID: 12612864; PubMed Central PMCID: PMC1180351. 18. Stein CM, Guwatudde D, Nakakeeto M, Peters P, Elston RC, Tiwari HK, Mugerwa R, Whalen CC. Heritability analysis of cytokines as intermediate phenotypes of tuberculosis. J Infect Dis. 2003 Jun 1;187(11):1679-85. Epub 2003 May 9. PubMed PMID: 12751024; PubMed Central PMCID: PMC3419478. 19. Wiener H, Elston RC, Tiwari HK. X-linked extension of the revised Haseman-Elston algorithm for linkage analysis in sib pairs. Hum Hered. 2003;55(2-3):97-107. PubMed PMID: 12931048. 20. Tiwari HK, Allison DB. Do allelic variants of SLC6A14 predispose to obesity? J Clin Invest. 2003 Dec;112(11):1633-6. PubMed PMID: 14660737; PubMed Central PMCID: PMC281657. 21. Rankinen T, Tiwari H. Genome scans for human nutritional traits: what have we learned? Nutrition. 2004 Jan;20(1):9-13. doi: 10.1016/j.nut.2003.09.004 Review. PubMed PMID: 14698008. 22. Bridges SL Jr, Hughes LB, Mikuls TR, Howard G, Tiwari HK, Alarcón GS, McNicholl JM, Moreland LW. Early rheumatoid arthritis in African-Americans: the CLEAR Registry. Clin Exp Rheumatol. 2003 Sep-Oct;21(5 Suppl 31):S138-45. Review. PubMed PMID: 14969066. 23. Stein CM, Song Y, Elston RC, Jun G, Tiwari HK, Iyengar SK. Structural equation model-based genome scan for the metabolic syndrome. BMC Genet. 2003 Dec 31;4 Suppl 1:S99. PubMed PMID: 14975167; PubMed Central PMCID: PMC1866540. 24. Criswell LA, Lum RF, Turner KN, Woehl B, Zhu Y, Wang J, Tiwari HK, Edberg JC, Kimberly RP, Moreland LW, Seldin MF, Bridges SL Jr. The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. Arthritis Rheum. 2004 Sep;50(9):2750-6. PubMed PMID: 15457442. 25. Tiwari HK, Holt J, George V, Beasley TM, Amos CI, Allison DB. New joint covariance- and marginal-based tests for association and linkage for quantitative traits for random and non-random sampling. Genet Epidemiol. 2005

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Jan;28(1):48-57. PubMed PMID: 15558568. 26. Puranam RS, Jain S, Kleindienst AM, Saxena S, Kim MK, Kelly Changizi B, Padma MV, Andrews I, Elston RC, Tiwari HK, McNamara JO. A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26. Ann Neurol. 2005 Sep;58(3):449-58. PubMed PMID: 16130088. 27. Tiwari HK, Bouchard L, Pérusse L, Allison DB. Is GAD2 on chromosome 10p12 a potential candidate gene for morbid obesity? Nutr Rev. 2005 Sep;63(9):315-9. Review. PubMed PMID: 16220643. 28. Matsuoka N, Patki A, Tiwari HK, Allison DB, Johnson SB, Gregersen PK, Leibel RL, Chung WK. Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African-American adults. Int J Obes (Lond). 2006 Feb;30(2):233-7. PubMed PMID: 16231022.

29. Hughes LB, Beasley TM, Patel H, Tiwari HK, Morgan SL, Baggott JE, Saag KG, McNicholl J, Moreland LW, Alarcón GS, Bridges SL Jr. Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis. Ann Rheum Dis. 2006 Sep;65(9):1213-8. Epub 2006 Jan 26. PubMed PMID: 16439441; PubMed Central PMCID: PMC1798268. 30. Wiener HW, Go RC, Tiwari H, George V, Page GP. COGA phenotypes and linkages on chromosome 2. BMC Genet. 2005 Dec 30;6 Suppl 1:S125. PubMed PMID: 16451583; PubMed Central PMCID: PMC1866812. 31. Redden DT, Divers J, Vaughan LK, Tiwari HK, Beasley TM, Fernández JR, Kimberly RP, Feng R, Padilla MA, Liu N, Miller MB, Allison DB. Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model. PLoS Genet. 2006 Aug 25;2(8):e137. Epub 2006 Jul 18. PubMed PMID: 16934005; PubMed Central PMCID: PMC1557785. 32. Matsuoka N, A Patki, Tiwari HK, Luke A, Johnson SB, Gregersen PK, Allison DB, Leibel RL, Chung WK (2007). Association of MC3R with Body Mass Index in African-Americans. International Journal of Body Composition. Vol 5, No 4: 123-129. 33. Musani SK, Shriner D, Liu N, Feng R, Coffey CS, Yi N, Tiwari HK, Allison DB. Detection of gene x gene interactions in genome-wide association studies of human population data. Hum Hered. 2007;63(2):67-84. Epub 2007 Feb 2. Review. PubMed PMID: 17283436. 34. Wessel J, Schork AJ, Tiwari HK, Schork NJ. Powerful designs for genetic association studies that consider twins and sibling pairs with discordant

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genotypes. Genet Epidemiol. 2007 Nov;31(7):789-96. PubMed PMID: 17549743. 35. Shriner D, Vaughan LK, Padilla MA, Tiwari HK. Problems with genome-wide association studies. Science. 2007 Jun 29;316(5833):1840-2. PubMed PMID: 17600199. 36. Li J, Cowden LG, King JD, Briles DA, Schroeder HW Jr, Stevens AB, Perry RT, Chen Z, Simmons MS, Wiener HW, Tiwari HK, Harrell LE, Go RC. Effects of chronic stress and interleukin-10 gene polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer's disease. Psychosom Med. 2007 Jul-Aug;69(6):551-9. Epub 2007 Jul 18. PubMed PMID: 17634568. 37. Wineinger NE, Kennedy RE, Erickson SW, Wojczynski MK, Bruder CE, Tiwari HK. Statistical issues in the analysis of DNA Copy Number Variations. Int J Comput Biol Drug Des. 2008;1(4):368-95. doi: 10.1504/IJCBDD.2008.022208. Review. PubMed PMID: 19774103; PubMed Central PMCID: PMC2747762. 38. Bruder CE, Piotrowski A, Gijsbers AA, Andersson R, Erickson S, Diaz de Ståhl T, Menzel U, Sandgren J, von Tell D, Poplawski A, Crowley M, Crasto C, Partridge EC, Tiwari H, Allison DB, Komorowski J, van Ommen GJ, Boomsma DI, Pedersen NL, den Dunnen JT, Wirdefeldt K, Dumanski JP. Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am J Hum Genet. 2008 Mar;82(3):763-71. doi: 10.1016/j.ajhg.2007.12.011. Epub 2008 Feb 14. PubMed PMID: 18304490; PubMed Central PMCID: PMC2427204. 39. Wojczynski MK, Tiwari HK. Definition of phenotype. Adv Genet. 2008;60:75-105. doi: 10.1016/S0065-2660(07)00404-X. Review. PubMed PMID: 18358317. 40. Tiwari HK, Barnholtz-Sloan J, Wineinger N, Padilla MA, Vaughan LK, Allison DB. Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles. Hum Hered. 2008;66(2):67-86. doi: 10.1159/000119107. Epub 2008 Mar 31. Review. PubMed PMID: 18382087; PubMed Central PMCID: PMC2803696. 41. Chung WK, Patki A, Matsuoka N, Boyer BB, Liu N, Musani SK, Goropashnaya AV, Tan PL, Katsanis N, Johnson SB, Gregersen PK, Allison DB, Leibel RL, Tiwari HK. Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations. Hum Hered. 2009;67(3):193-205. doi: 10.1159/000181158. Epub 2008 Dec 15. PubMed PMID: 19077438; PubMed Central PMCID: PMC2715950. 42. Feng R, McClure LA, Tiwari HK, Howard G. A new estimate of family disease history providing improved prediction of disease risks. Stat Med. 2009

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Apr 15;28(8):1269-83. doi: 10.1002/sim.3526. PubMed PMID: 19170247; PubMed Central PMCID: PMC3193605. 43. Baye TM, Tiwari HK, Allison DB, Go RC. Database mining for selection of SNP markers useful in admixture mapping. BioData Min. 2009 Feb 14;2(1):1. doi: 10.1186/1756-0381-2-1. PubMed PMID: 19216798; PubMed Central PMCID: PMC2649128. 44. Padilla MA, Divers J, Vaughan LK, Allison DB, Tiwari HK. Multiple imputation to correct for measurement error in admixture estimates in genetic structured association testing. Hum Hered. 2009;68(1):65-72. doi: 10.1159/000210450. Epub 2009 Apr 1. PubMed PMID: 19339787; PubMed Central PMCID: PMC2716289. 45. Gibson AW, Li FJ, Wu J, Edberg JC, Su K, Cafardi J, Wiener H, Tiwari H, Kimberly RP, Davis RS. The FCRL3-169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+ B cells. Arthritis Rheum. 2009 Nov;60(11):3510-2. doi: 10.1002/art.24915. PubMed PMID: 19877046; PubMed Central PMCID: PMC2784265. 46. Vaughan LK, Divers J, Padilla M, Redden DT, Tiwari HK, Pomp D, Allison DB. The use of plasmodes as a supplement to simulations: A simple example evaluating individual admixture estimation methodologies. Comput Stat Data Anal. 2009 Mar 15;53(5):1755-1766. PubMed PMID: 20161321; PubMed Central PMCID: PMC2678733. 47. Shrestha S, Aissani B, Tiwari HK, Wiener HW. Association test of multiallelic gene copy numbers in family trios. Genet Epidemiol. 2010 Jan;34(1):2-6. doi: 10.1002/gepi.20426. PubMed PMID: 19399904. 48. Zhang Z, Ersoz E, Lai CQ, Todhunter RJ, Tiwari HK, Gore MA, Bradbury PJ, Yu J, Arnett DK, Ordovas JM, Buckler ES. Mixed linear model approach adapted for genome-wide association studies. Nat Genet. 2010 Apr;42(4):355-60. doi: 10.1038/ng.546. Epub 2010 Mar 7. PubMed PMID: 20208535; PubMed Central PMCID: PMC2931336. 49. Irvin MR, Lynch AI, Kabagambe EK, Tiwari HK, Barzilay JI, Eckfeldt JH, Boerwinkle E, Davis BR, Ford CE, Arnett DK. Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. J Hypertens. 2010 Oct;28(10):2076-83. doi: 10.1097/HJH.0b013e32833c7a4d. PubMed PMID: 20577119; PubMed Central PMCID: PMC2957368. 50. Tiwari HK, Patki A, Allison DB. Within-Cluster Resampling for Analysis of Family Data: Ready for Prime-Time? Stat Interface. 2010 Apr 1;3(2):169-176. PubMed PMID: 20664749; PubMed Central PMCID: PMC2907179.

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51. Irvin MR, Kabagambe EK, Tiwari HK, Parnell LD, Straka RJ, Tsai M, Ordovas JM, Arnett DK. Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study. Circ Cardiovasc Genet. 2010 Oct;3(5):462-7. doi: 10.1161/CIRCGENETICS.110.950667. Epub 2010 Aug 21. PubMed PMID: 20729559; PubMed Central PMCID: PMC3119521. 52. De Luca M, Crocco P, Wiener H, Tiwari HK, Passarino G, Rose G. Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjects. Exp Gerontol. 2011 Jan;46(1):60-4. doi: 10.1016/j.exger.2010.10.003. Epub 2010 Oct 14. PubMed PMID: 20951195; PubMed Central PMCID: PMC2998567. 53. You Z, Williams OD, Aban I, Kabagambe EK, Tiwari HK, Cutter G. Relative efficiency and sample size for cluster randomized trials with variable cluster sizes. Clin Trials. 2011 Feb;8(1):27-36. doi: 10.1177/1740774510391492. Epub 2010 Dec 16. PubMed PMID: 21163852. 54. Arnett DK, Meyers KJ, Devereux RB, Tiwari HK, Gu CC, Vaughan LK, Perry RT, Patki A, Claas SA, Sun YV, Broeckel U, Kardia SL. Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families. Circ Res. 2011 Feb 4;108(3):279-83. doi: 10.1161/CIRCRESAHA.110.239210. Epub 2011 Jan 6. PubMed PMID: 21212386; PubMed Central PMCID: PMC3328104. 55. Wineinger NE, Patki A, Meyers KJ, Broeckel U, Gu CC, Rao DC, Devereux RB, Arnett DK, Tiwari HK. Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study. BMC Med Genomics. 2011 Jan 11;4:4. doi: 10.1186/1755-8794-4-4. PubMed PMID: 21223598; PubMed Central PMCID: PMC3027088. 56. Wineinger NE, Pajewski NM, Tiwari HK. A Method to Assess Linkage Disequilibrium between CNVs and SNPs Inside Copy Number Variable Regions. Front Genet. 2011 Apr 25;2:17. doi: 10.3389/fgene.2011.00017. eCollection 2011. PubMed PMID: 21660233; PubMed Central PMCID: PMC3109359. 57. Wineinger NE, Pajewski NM, Kennedy RE, Wojczynski MK, Vaughan LK, Hunt SC, Gu CC, Rao DC, Lorier R, Broeckel U, Arnett DK, Tiwari HK. Characterization of autosomal copy-number variation in African Americans: the HyperGEN Study. Eur J Hum Genet. 2011 Dec;19(12):1271-5. doi: 10.1038/ejhg.2011.115. Epub 2011 Jun 15. PubMed PMID: 21673747; PubMed Central PMCID: PMC3230358. 58. Howard G, McClure LA, Moy CS, Safford MM, Cushman M, Judd SE, Kissela BM, Kleindorfer DO, Howard VJ, Rhodes DJ, Muntner P, Tiwari HK. Imputation of incident events in longitudinal cohort studies. Am J Epidemiol. 2011 Sep 15;174(6):718-26. doi: 10.1093/aje/kwr155. Epub 2011 Jul 29. PubMed PMID:

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21804050; PubMed Central PMCID: PMC3166710. 59. Wood AC, Glasser S, Garvey WT, Kabagambe EK, Borecki IB, Tiwari HK, Tsai MY, Hopkins PN, Ordovas JM, Arnett DK. Lipoprotein lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS. Lipids Health Dis. 2011 Aug 19;10:143. doi: 10.1186/1476-511X-10-143. PubMed PMID: 21854610; PubMed Central PMCID: PMC3180704. 60. Irvin MR, Shrestha S, Chen YD, Wiener HW, Haritunians T, Vaughan LK, Tiwari HK, Taylor KD, Scherzer R, Saag MS, Grunfeld C, Rotter JI, Arnett DK. Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men. Pharmacogenet Genomics. 2011 Dec;21(12):798-807. doi: 10.1097/FPC.0b013e32834b68f9. PubMed PMID: 21897333; PubMed Central PMCID: PMC3210910. 61. Irvin MR, Wineinger NE, Rice TK, Pajewski NM, Kabagambe EK, Gu CC, Pankow J, North KE, Wilk JB, Freedman BI, Franceschini N, Broeckel U, Tiwari HK, Arnett DK. Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. PLoS One. 2011;6(8):e24052. doi: 10.1371/journal.pone.0024052. Epub 2011 Aug 25. PubMed PMID: 21901158; PubMed Central PMCID: PMC3162025. 62. Wood AC, Kabagambe EK, Borecki IB, Tiwari HK, Ordovas JM, Arnett DK. Dietary Carbohydrate Modifies the Inverse Association Between Saturated Fat Intake and Cholesterol on Very Low-Density Lipoproteins. Lipid Insights. 2011 Aug 23;2011(4):7-15. PubMed PMID: 21912485; PubMed Central PMCID: PMC3170517. 63. Tiwari HK, Birkner T, Moondan A, Zhang S, Page GP, Patki A, Allison DB. Accurate and flexible power calculations on the spot: Applications to genomic research. Stat Interface. 2011;4(3):353-358. PubMed PMID: 22022634; PubMed Central PMCID: PMC3196559. 64. Tiwari HK, Patki A, Lieberman J, Stroup TS, Allison DB, Leibel RL, Chung WK. Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study). Front Genet. 2011 Sep 1;2:56. doi: 10.3389/fgene.2011.00056. Print 2011. PubMed PMID: 22039372; PubMed Central PMCID: PMC3202977. 65. Lemas DJ, Wiener HW, O'Brien DM, Hopkins S, Stanhope KL, Havel PJ, Allison DB, Fernandez JR, Tiwari HK, Boyer BB. Genetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik Eskimos. J Lipid Res. 2012 Jan;53(1):175-84. doi: 10.1194/jlr.P018952. Epub 2011 Nov 1. PubMed PMID: 22045927; PubMed Central PMCID: PMC3243474.

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66. Azuero A, Redden DT, Tiwari HK, Asmellash SG, Piyathilake CJ. A Simple Distribution-Free Algorithm for Generating Simulated High-Dimensional Correlated Data with an Autoregressive Structure. Commun Stat Simul Comput. 2012 Jan 1;41(1):89-98. PubMed PMID: 22102768; PubMed Central PMCID: PMC3217303. 67. Frazier-Wood AC, Glasser S, Garvey WT, Kabagambe EK, Borecki IB, Tiwari HK, Tsai MY, Hopkins PN, Ordovas JM, Arnett DK. A clustering analysis of lipoprotein diameters in the metabolic syndrome. Lipids Health Dis. 2011 Dec 19;10:237. doi: 10.1186/1476-511X-10-237. PubMed PMID: 22182248; PubMed Central PMCID: PMC3260106. 68. Aslibekyan S, Kabagambe EK, Irvin MR, Straka RJ, Borecki IB, Tiwari HK, Tsai MY, Hopkins PN, Shen J, Lai CQ, Ordovas JM, Arnett DK. A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. Pharmacogenet Genomics. 2012 Mar;22(3):191-7. doi: 10.1097/FPC.0b013e32834fdd41. PubMed PMID: 22228203; PubMed Central PMCID: PMC3275691. 69. Tiwari HK, Schork NJ. Grand challenges in statistical genetics/genomics methodology. Front Genet. 2011 Feb 24;2:5. doi: 10.3389/fgene.2011.00005. eCollection 2011. PubMed PMID: 22303304; PubMed Central PMCID: PMC3268565. 70. Forsberg LA, Rasi C, Razzaghian HR, Pakalapati G, Waite L, Thilbeault KS, Ronowicz A, Wineinger NE, Tiwari HK, Boomsma D, Westerman MP, Harris JR, Lyle R, Essand M, Eriksson F, Assimes TL, Iribarren C, Strachan E, O'Hanlon TP, Rider LG, Miller FW, Giedraitis V, Lannfelt L, Ingelsson M, Piotrowski A, Pedersen NL, Absher D, Dumanski JP. Age-related somatic structural changes in the nuclear genome of human blood cells. Am J Hum Genet. 2012 Feb 10;90(2):217-28. doi: 10.1016/j.ajhg.2011.12.009. Epub 2012 Feb 2. PubMed PMID: 22305530; PubMed Central PMCID: PMC3276669. 71. Kennedy RE, Howard G, Go RC, Rothwell PM, Tiwari HK, Feng R, McClure LA, Prineas RJ, Banerjee A, Arnett DK. Association between family risk of stroke and myocardial infarction with prevalent risk factors and coexisting diseases. Stroke. 2012 Apr;43(4):974-9. doi: 10.1161/STROKEAHA.111.645044. Epub 2012 Feb 9. PubMed PMID: 22328552; PubMed Central PMCID: PMC3805250.

72. Irvin MR, Zhang Q, Kabagambe EK, Perry RT, Straka RJ, Tiwari HK, Borecki IB, Shimmin LC, Stuart C, Zhong Y, Hixson JE, Arnett DK. Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network Study. Pharmacogenet Genomics. 2012 May;22(5):367-72. doi: 10.1097/FPC.0b013e328351a486. PubMed PMID: 22336959; PubMed Central PMCID: PMC3325369.

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73. Frazier-Wood AC, Kabagambe EK, Borecki IB, Tiwari HK, Ordovas JM, Arnett DK. Preliminary evidence for an association between LRP-1 genotype and body mass index in humans. PLoS One. 2012;7(2):e30732. doi: 10.1371/journal.pone.0030732. Epub 2012 Feb 8. PubMed PMID: 22347399; PubMed Central PMCID: PMC3275600. 74. Lin WY, Tiwari HK, Gao G, Zhang K, Arcaroli JJ, Abraham E, Liu N. Similarity-based multimarker association tests for continuous traits. Ann Hum Genet. 2012 May;76(3):246-60. doi: 10.1111/j.1469-1809.2012.00706.x. PubMed PMID: 22497480; PubMed Central PMCID: PMC3329946. 75. Wineinger NE, Tiwari HK. The impact of errors in copy number variation detection algorithms on association results. PLoS One. 2012;7(4):e32396. doi: 10.1371/journal.pone.0032396. Epub 2012 Apr 16. PubMed PMID: 22523537; PubMed Central PMCID: PMC3327691. 76. Frazier-Wood AC, Ordovas JM, Straka RJ, Hixson JE, Borecki IB, Tiwari HK, Arnett DK. The PPAR alpha gene is associated with triglyceride, low-density cholesterol and inflammation marker response to fenofibrate intervention: the GOLDN study. Pharmacogenomics J. 2013 Aug;13(4):312-7. doi: 10.1038/tpj.2012.9. Epub 2012 May 1. PubMed PMID: 22547144; PubMed Central PMCID: PMC3410976. 77. Sung YJ, Gu CC, Tiwari HK, Arnett DK, Broeckel U, Rao DC. Genotype imputation for African Americans using data from HapMap phase II versus 1000 genomes projects. Genet Epidemiol. 2012 Jul;36(5):508-16. doi: 10.1002/gepi.21647. Epub 2012 May 29. PubMed PMID: 22644746; PubMed Central PMCID: PMC3703942. 78. Zhi D, Irvin MR, Gu CC, Stoddard AJ, Lorier R, Matter A, Rao DC, Srinivasasainagendra V, Tiwari HK, Turner A, Broeckel U, Arnett DK. Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophy. Front Genet. 2012 May 28;3:92. doi: 10.3389/fgene.2012.00092. eCollection 2012. PubMed PMID: 22654895; PubMed Central PMCID: PMC3361011. 79. Lin WY, Yi N, Zhi D, Zhang K, Gao G, Tiwari HK, Liu N. Haplotype-based methods for detecting uncommon causal variants with common SNPs. Genet Epidemiol. 2012 Sep;36(6):572-82. doi: 10.1002/gepi.21650. Epub 2012 Jun 15. PubMed PMID: 22706849; PubMed Central PMCID: PMC3513398. 80. Zhao W, Wineinger NE, Tiwari HK, Mosley TH, Broeckel U, Arnett DK, Kardia SL, Kabagambe EK, Sun YV. Copy number variations associated with obesity-related traits in African Americans: a joint analysis between GENOA and HyperGEN. Obesity (Silver Spring). 2012 Dec;20(12):2431-7. doi: 10.1038/oby.2012.162. Epub 2012 Jun 22. PubMed PMID: 22836685; PubMed

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Central PMCID: PMC3484176. 81. Frazier-Wood AC, Aslibekyan S, Borecki IB, Hopkins PN, Lai CQ, Ordovas JM, Straka RJ, Tiwari HK, Arnett DK. Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate. Pharmacogenet Genomics. 2012 Oct;22(10):750-7. PubMed PMID: 22890011; PubMed Central PMCID: PMC3760420. 82. Aslibekyan S, Goodarzi MO, Frazier-Wood AC, Yan X, Irvin MR, Kim E, Tiwari HK, Guo X, Straka RJ, Taylor KD, Tsai MY, Hopkins PN, Korenman SG, Borecki IB, Chen YD, Ordovas JM, Rotter JI, Arnett DK. Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate. PLoS One. 2012;7(10):e48663. doi: 10.1371/journal.pone.0048663. Epub 2012 Oct 31. PubMed PMID: 23119086; PubMed Central PMCID: PMC3485381.

83. You Z, Williams OD, Aban I, Kabagambe EK, Tiwari HK, Cutter G. Response to the Letter 'Efficiency loss due to varying cluster sizes in cluster randomized trials and how to compensate for it: comment on You et al. (2011)' by van Breukelen and Candel. Clin Trials. 2012;9(1):126-7. No abstract available. PMID: 22334470

84. Aslibekyan S, An P, Frazier-Wood AC, Kabagambe EK, Irvin MR, Straka RJ, Tiwari HK, Tsai MY, Hopkins PN, Borecki IB, Ordovas JM, Arnett DK. Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Nutr Metab Cardiovasc Dis. 2013 Oct;23(10):987-94. doi: 10.1016/j.numecd.2012.07.010. Epub 2012 Nov 11. PubMed PMID: 23149075; PubMed Central PMCID: PMC3578131. 85. Frazier-Wood AC, Manichaikul A, Aslibekyan S, Borecki IB, Goff DC, Hopkins PN, Lai CQ, Ordovas JM, Post WS, Rich SS, Sale MM, Siscovick D, Straka RJ, Tiwari HK, Tsai MY, Rotter JI, Arnett DK. Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Hum Genet. 2013 Apr;132(4):405-13. doi: 10.1007/s00439-012-1256-1. Epub 2012 Dec 22. PubMed PMID: 23263444; PubMed Central PMCID: PMC3600091. 86. Makowsky R, Yan Q, Wiener HW, Sandel M, Aissani B, Tiwari HK, Shrestha S. The utility of mitochondrial and y chromosome phylogenetic data to improve correction for population stratification. Front Genet. 2012 Dec 21;3:301. doi: 10.3389/fgene.2012.00301. eCollection 2012. PubMed PMID: 23267368; PubMed Central PMCID: PMC3527715. 87. Frazier-Wood AC, Kabagambe EK, Wojczynski MK, Borecki IB, Tiwari HK, Smith CE, Ordovas JM, Arnett DK. The association between LRP-1 variants and chylomicron uptake after a high fat meal. Nutr Metab Cardiovasc Dis. 2013

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Nov;23(11):1154-8. doi: 10.1016/j.numecd.2012.12.007. Epub 2013 Feb 26. PubMed PMID: 23484911; PubMed Central PMCID: PMC3686991. 88. Lemas DJ, Klimentidis YC, Wiener HH, O'Brien DM, Hopkins SE, Allison DB, Fernandez JR, Tiwari HK, Boyer BB. Obesity polymorphisms identified in genome-wide association studies interact with n-3 polyunsaturated fatty acid intake and modify the genetic association with adiposity phenotypes in Yup'ik people. Genes Nutr. 2013 Sep;8(5):495-505. doi: 10.1007/s12263-013-0340-z. Epub 2013 Mar 23. PubMed PMID: 23526194; PubMed Central PMCID: PMC3755132. 89. Lin WY, Yi N, Lou XY, Zhi D, Zhang K, Gao G, Tiwari HK, Liu N. Haplotype kernel association test as a powerful method to identify chromosomal regions harboring uncommon causal variants. Genet Epidemiol. 2013 Sep;37(6):560-70. doi: 10.1002/gepi.21740. Epub 2013 Jun 5. PubMed PMID: 23740760; PubMed Central PMCID: PMC4116485. 90. Kennedy RE, Adragni KP, Tiwari HK, Voeks JH, Brott TG, Howard G. Risk-stratified imputation in survival analysis. Clin Trials. 2013 Aug;10(4):530-9. doi: 10.1177/1740774513493150. Epub 2013 Jul 1. PubMed PMID: 23818434; PubMed Central PMCID: PMC3807795. 91. Li P, Tiwari HK, Lin WY, Allison DB, Chung WK, Leibel RL, Yi N, Liu N. Genetic association analysis of 30 genes related to obesity in a European American population. Int J Obes (Lond). 2014 May;38(5):724-9. doi: 10.1038/ijo.2013.140. Epub 2013 Jul 31. PubMed PMID: 23900445; PubMed Central PMCID: PMC3909018. 92. Aslibekyan S, Vaughan LK, Wiener HW, Lemas DJ, Klimentidis YC, Havel PJ, Stanhope KL, O'brien DM, Hopkins SE, Boyer BB, Tiwari HK. Evidence for novel genetic loci associated with metabolic traits in Yup'ik people. Am J Hum Biol. 2013 Sep-Oct;25(5):673-80. doi: 10.1002/ajhb.22429. Epub 2013 Aug 1. PubMed PMID: 23907821; PubMed Central PMCID: PMC3785243. 93. Danila MI, Reynolds RJ, Tiwari HK, Bridges SL Jr. Ethnic-specific genetic analyses in rheumatoid arthritis: incremental gains but valuable contributions to the big picture. Arthritis Rheum. 2013 Dec;65(12):3014-6. doi: 10.1002/art.38111. PubMed PMID: 23918636; PubMed Central PMCID: PMC3987110. 94. Klimentidis YC, Lemas DJ, Wiener HH, O'Brien DM, Havel PJ, Stanhope KL, Hopkins SE, Tiwari HK, Boyer BB. CDKAL1 and HHEX are associated with type 2 diabetes-related traits among Yup'ik people. J Diabetes. 2014 May;6(3):251-9. doi: 10.1111/1753-0407.12093. Epub 2013 Oct 29. PubMed PMID: 24112421; PubMed Central PMCID: PMC3964139. 95. Hidalgo B, Irvin MR, Sha J, Zhi D, Aslibekyan S, Absher D, Tiwari HK,

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Kabagambe EK, Ordovas JM, Arnett DK. Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network study. Diabetes. 2014 Feb;63(2):801-7. doi: 10.2337/db13-1100. Epub 2013 Oct 29. PubMed PMID: 24170695; PubMed Central PMCID: PMC3968438. 96. Aslibekyan S, Wiener HW, Havel PJ, Stanhope KL, O'Brien DM, Hopkins SE, Absher DM, Tiwari HK, Boyer BB. DNA methylation patterns are associated with n-3 fatty acid intake in Yup'ik people. J Nutr. 2014 Apr;144(4):425-30. doi: 10.3945/jn.113.187203. Epub 2014 Jan 29. PubMed PMID: 24477300; PubMed Central PMCID: PMC3952620. 97. Frazier-Wood AC, Aslibekyan S, Absher DM, Hopkins PN, Sha J, Tsai MY, Tiwari HK, Waite LL, Zhi D, Arnett DK. Methylation at CPT1A locus is associated with lipoprotein subfraction profiles. J Lipid Res. 2014 Apr 7;55(7):1324-1330. [Epub ahead of print] PubMed PMID: 24711635; PubMed Central PMCID: PMC4076093. 98. Yan Q, Tiwari HK, Yi N, Lin WY, Gao G, Lou XY, Cui X, Liu N. Kernel-machine testing coupled with a rank-truncation method for genetic pathway analysis. Genet Epidemiol. 2014 Jul;38(5):447-56. doi: 10.1002/gepi.21813. Epub 2014 May 21. PubMed PMID: 24849109; PubMed Central PMCID: PMC4073214. 99. Irvin MR, Zhi D, Aslibekyan S, Claas SA, Absher DM, Ordovas JM, Tiwari HK, Watkins S, Arnett DK. Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study. PLoS One. 2014 Jun 6;9(6):e99509. doi: 10.1371/journal.pone.0099509. eCollection 2014. PubMed PMID: 24905834; PubMed Central PMCID: PMC4048279. 100. Irvin MR, Zhi D, Joehanes R, Mendelson M, Aslibekyan S, Claas SA, Thibeault KS, Patel N, Day K, Jones LW, Liang L, Chen BH, Yao C, Tiwari HK, Ordovas JM, Levy D, Absher D, Arnett DK. Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study. Circulation. 2014 Aug 12;130(7):565-72. doi: 10.1161/CIRCULATIONAHA.114.009158. Epub 2014 Jun 11. PubMed PMID: 24920721; PubMed Central PMCID: PMC4209699. 101. Frazier-Wood AC, Wojczynski MK, Borecki IB, Hopkins PN, Lai CQ, Ordovas JM, Straka RJ, Tsai MY, Tiwari HK, Arnett DK. Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate. Biology (Basel). 2014 Aug 25;3(3):536-50. doi: 10.3390/biology3030536. PubMed PMID: 25157911; PubMed Central PMCID: PMC4192626. 102. Do AN, Irvin MR, Lynch AI, Claas SA, Boerwinkle E, Davis BR, Ford CE, Eckfeldt JH, Tiwari HK, Limdi NA, Arnett DK. The effects of angiotensinogen

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gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study. Front Pharmacol. 2014 Sep 16;5:210. doi: 10.3389/fphar.2014.00210. eCollection 2014. PubMed PMID: 25278896; PubMed Central PMCID: PMC4165277.

103. Hill AE, Plyler ZE, Tiwari H, Patki A, Tully JP, McAtee CW, Moseley LA, Sorscher EJ. Longevity and plasticity of CFTR provide an argument for noncanonical SNP organization in hominid DNA. PLoS One. 2014 Oct 28;9(10):e109186. doi: 10.1371/journal.pone.0109186. eCollection 2014. PubMed PMID: 25350658; PubMed Central PMCID: PMC4211684.

104. Vaughan LK, Wiener HW, Aslibekyan S, Allison DB, Havel PJ, Stanhope KL, O'Brien DM, Hopkins SE, Lemas DJ, Boyer BB, Tiwari HK. Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population. Metabolism. 2015 Jun;64(6):689-97. doi: 10.1016/j.metabol.2015.02.008. Epub 2015 Mar 5. PubMed PMID: 25772781; PubMed Central PMCID: PMC4408244. 105. Yan Q, Tiwari HK, Yi N, Gao G, Zhang K, Lin WY, Lou XY, Cui X, Liu N. A Sequence Kernel Association Test for Dichotomous Traits in Family Samples under a Generalized Linear Mixed Model. Hum Hered. 2015;79(2):60-8. doi: 10.1159/000375409. Epub 2015 Mar 10. PubMed PMID: 25791389.

106. Lebrón-Aldea D, Dhurandhar EJ, Pérez-Rodríguez P, Klimentidis YC, Tiwari HK, Vazquez AI. Integrated genomic and BMI analysis for type 2 diabetes risk assessment. Front Genet. 2015 Mar 17;6:75. doi: 10.3389/fgene.2015.00075. eCollection 2015. PubMed PMID: 25852736; PubMed Central PMCID: PMC4362394.

107. Tran NT, Aslibekyan S, Tiwari HK, Zhi D, Sung YJ, Hunt SC, Rao DC, Broeckel U, Judd SE, Muntner P, Kent ST, Arnett DK, Irvin MR. PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies. Front Genet. 2015 Apr 8;6:136. doi: 10.3389/fgene.2015.00136. eCollection 2015. PubMed PMID: 25904937; PubMed Central PMCID: PMC4389541. 108. Fohner AE, Robinson R, Yracheta J, Dillard DA, Schilling B, Khan B, Hopkins S, Boyer BB, Black J, Wiener H, Tiwari HK, Gordon A, Nickerson D, Tsai JM, Farin FM, Thornton TA, Rettie AE, Thummel KE. Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX. Pharmacogenet Genomics. 2015 Jul;25(7):343-53. doi: 10.1097/FPC.0000000000000143. PubMed PMID: 25946405; PubMed Central PMCID: PMC4461509. 109. Owolabi MO, Akarolo-Anthony S, Akinyemi R, Arnett D, Gebregziabher M, Jenkins C, Tiwari H, Arulogun O, Akpalu A, Sarfo FS, Obiako R, Owolabi L, Sagoe K, Melikam S, Adeoye AM, Lackland D, Ovbiagele B; Members of the

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H3Africa Consortium. The burden of stroke in Africa: a glance at the present and a glimpse into the future. Cardiovasc J Afr. 2015 Mar-Apr;26(2 Suppl 1):S27-38. doi: 10.5830/CVJA-2015-038. Review. PubMed PMID: 25962945; PubMed Central PMCID: PMC4557491. 110. Akinyemi RO, Ovbiagele B, Akpalu A, Jenkins C, Sagoe K, Owolabi L, Sarfo F, Obiako R, Gebreziabher M, Melikam E, Warth S, Arulogun O, Lackland D, Ogunniyi A, Tiwari H, Kalaria RN, Arnett D, Owolabi MO; SIREN Investigators as Members of the H3Africa Consortium. Stroke genomics in people of African ancestry: charting new paths. Cardiovasc J Afr. 2015 Mar-Apr;26(2 Suppl 1):S39-49. doi: 10.5830/CVJA-2015-039. Review. PubMed PMID: 25962947; PubMed Central PMCID: PMC4557488. 111. Aslibekyan S, Demerath EW, Mendelson M, Zhi D, Guan W, Liang L, Sha J, Pankow JS, Liu C, Irvin MR, Fornage M, Hidalgo B, Lin LA, Thibeault KS, Bressler J, Tsai MY, Grove ML, Hopkins PN, Boerwinkle E, Borecki IB, Ordovas JM, Levy D, Tiwari HK, Absher DM, Arnett DK. Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference. Obesity (Silver Spring). 2015 Jul;23(7):1493-501. doi: 10.1002/oby.21111. PubMed PMID: 26110892; PubMed Central PMCID: PMC4482015. 112. Hidalgo B, Aslibekyan S, Wiener HW, Irvin MR, Straka RJ, Borecki IB, Tiwari HK, Tsai MY, Hopkins PN, Ordovas JM, Arnett DK. A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network. Pharmacogenet Genomics. 2015 Oct;25(10):511-4. doi: 10.1097/FPC.0000000000000162. PubMed PMID: 26203732; PubMed Central PMCID: PMC4558213. 113. Benza RL, Gomberg-Maitland M, Demarco T, Frost AE, Torbicki A, Langleben D, Pulido T, Correa-Jaque P, Passineau MJ, Wiener HW, Tamari M, Hirota T, Kubo M, Tiwari HK. Endothelin-1 Pathway Polymorphisms and Outcomes in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1345-54. doi: 10.1164/rccm.201501-0196OC. PubMed PMID: 26252367; PubMed Central PMCID: PMC4731699. 114. Wojczynski MK, Parnell LD, Pollin TI, Lai CQ, Feitosa MF, O'Connell JR, Frazier-Wood AC, Gibson Q, Aslibekyan S, Ryan KA, Province MA, Tiwari HK, Ordovas JM, Shuldiner AR, Arnett DK, Borecki IB. Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). Metabolism. 2015 Oct;64(10):1359-71. doi: 10.1016/j.metabol.2015.07.001. Epub 2015 Jul 3. PubMed PMID: 26256467; PubMed Central PMCID: PMC4573277. 115. Akpalu A, Sarfo FS, Ovbiagele B, Akinyemi R, Gebregziabher M, Obiako R, Owolabi L, Sagoe K, Jenkins C, Arulogun O, Adamu S, Appiah LT, Adadey MA,

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Agyekum F, Quansah JA, Mensah YB, Adeoye AM, Singh A, Tosin AO, Ohifemen O, Sani AA, Tabi-Ajayi E, Phillip IO, Isah SY, Tabari NA, Mande A, Agunloye AM, Ogbole GI, Akinyemi JO, Akpa OM, Laryea R, Melikam SE, Adinku D, Uvere E, Burkett NS, Adekunle GF, Kehinde SI, Azuh PC, Dambatta AH, Ishaq NA, Arnett D, Tiwari HK, Lackland D, Owolabi M; SIREN as part of the H3Africa Consortium. Phenotyping Stroke in Sub-Saharan Africa: Stroke Investigative Research and Education Network (SIREN) Phenomics Protocol. Neuroepidemiology. 2015;45(2):73-82. doi: 10.1159/000437372. Epub 2015 Aug 19. PubMed PMID: 26304844; PubMed Central PMCID: PMC4604029. 116. Singh B, Owens KM, Bajpai P, Desouki MM, Srinivasasainagendra V, Tiwari HK, Singh KK. Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties. PLoS One. 2015 Oct 15;10(10):e0139846. doi: 10.1371/journal.pone.0139846. eCollection 2015. PubMed PMID: 26468652; PubMed Central PMCID: PMC4607296. 117. Yan Q, Weeks DE, Celedón JC, Tiwari HK, Li B, Wang X, Lin WY, Lou XY, Gao G, Chen W, Liu N. Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method. Genetics. 2015 Dec;201(4):1329-39. doi: 10.1534/genetics.115.178590. Epub 2015 Oct 19. PubMed PMID: 26482791; PubMed Central PMCID: PMC4676518. 118. Das M, Irvin MR, Sha J, Aslibekyan S, Hidalgo B, Perry RT, Zhi D, Tiwari HK, Absher D, Ordovas JM, Arnett DK. Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study. Front Genet. 2015 Sep 29;6:304. doi: 10.3389/fgene.2015.00304. eCollection 2015. PubMed PMID: 26483836; PubMed Central PMCID: PMC4586504. 119. Sarfo F, Gebregziabher M, Ovbiagele B, Akinyemi R, Owolabi L, Obiako R, Akpa O, Armstrong K, Akpalu A, Adamu S, Obese V, Boa-Antwi N, Appiah L, Arulogun O, Mensah Y, Adeoye A, Tosin A, Adeleye O, Tabi-Ajayi E, Phillip I, Sani A, Isah S, Tabari N, Mande A, Agunloye A, Ogbole G, Akinyemi J, Laryea R, Melikam S, Uvere E, Adekunle G, Kehinde S, Azuh P, Dambatta A, Ishaq N, Saulson R, Arnett D, Tiwari H, Jenkins C, Lackland D, Owolabi M; Stroke Investigative Research Educational Networks. Multilingual Validation of the Questionnaire for Verifying Stroke-Free Status in West Africa. Stroke. 2016 Jan;47(1):167-72. doi: 10.1161/STROKEAHA.115.010374. Epub 2015 Nov 17. PubMed PMID: 26578660; PubMed Central PMCID: PMC4696900. 120. Fohner AE, Wang Z, Yracheta J, O'Brien DM, Hopkins SE, Black J, Philip J, Wiener HW, Tiwari HK, Stapleton PL, Tsai JM, Thornton TA, Boyer BB, Thummel KE. Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska. J Nutr. 2016 Feb;146(2):318-25. doi:

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10.3945/jn.115.223388. Epub 2015 Dec 9. PubMed PMID: 26661839; PubMed Central PMCID: PMC4725435. 121. Ma Y, Follis JL, Smith CE, Tanaka T, Manichaikul AW, Chu AY, Samieri C, Zhou X, Guan W, Wang L, Biggs ML, Chen YD, Hernandez DG, Borecki I, Chasman DI, Rich SS, Ferrucci L, Irvin MR, Aslibekyan S, Zhi D, Tiwari HK, Claas SA, Sha J, Kabagambe EK, Lai CQ, Parnell LD, Lee YC, Amouyel P, Lambert JC, Psaty BM, King IB, Mozaffarian D, McKnight B, Bandinelli S, Tsai MY, Ridker PM, Ding J, Mstat KL, Liu Y, Sotoodehnia N, Barberger-Gateau P, Steffen LM, Siscovick DS, Absher D, Arnett DK, Ordovás JM, Lemaitre RN. Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Am J Clin Nutr. 2016 Feb;103(2):567-78. doi: 10.3945/ajcn.115.112987. Epub 2016 Jan 20. PubMed PMID: 26791180. 122. Do AN, Lynch AI, Claas SA, Boerwinkle E, Davis BR, Ford CE, Eckfeldt JH, Tiwari HK, Arnett DK, Irvin MR. The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naïve hypertensive African Americans in the GenHAT study. J Hum Hypertens. 2016 Jan 21. doi: 10.1038/jhh.2015.121. [Epub ahead of print] PubMed PMID: 26791477. 123. Das M, Sha J, Hidalgo B, Aslibekyan S, Do AN, Zhi D, Sun D, Zhang T, Li S, Chen W, Srinivasan SR, Tiwari HK, Absher D, Ordovas JM, Berenson GS, Arnett DK, Irvin MR. Association of DNA Methylation at CPT1A Locus with Metabolic Syndrome in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study. PLoS One. 2016 Jan 25;11(1):e0145789. doi: 10.1371/journal.pone.0145789. eCollection 2016. PubMed PMID: 26808626; PubMed Central PMCID: PMC4726462. 124. Waite LL, Weaver B, Day K, Li X, Roberts K, Gibson AW, Edberg JC, Kimberly RP, Absher DM, Tiwari HK. Estimation of Cell-Type Composition Including T and B Cell Subtypes for Whole Blood Methylation Microarray Data. Front Genet. 2016 Feb 18;7:23. doi: 10.3389/fgene.2016.00023. eCollection 2016. PMID: 26925097; PMCID: 4757643 125. Mallick H, Tiwari HK. EM Adaptive LASSO-A Multilocus Modeling Strategy for Detecting SNPs Associated with Zero-inflated Count Phenotypes. Front Genet. 2016 Mar 30;7:32. eCollection 2016. PMID: 27066062

126. Yan Q, Weeks DE, Tiwari HK, Yi N, Zhang K, Gao G, Lin WY, Lou XY, Chen W, Liu N.Rare-Variant Kernel Machine Test for Longitudinal Data from Population and Family Samples. Hum Hered. 2016 Apr 29;80(3):126-138. [Epub ahead of print] PMID: 27161037

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127. Akinyemi RO, Owolabi MO, Oyeniyi T, Ovbiagele B, Arnett DK, Tiwari HK, Walker R, Ogunniyi A, Kalaria RN; SIREN group of H3Africa Consortium. Neurogenomics in Africa: Perspectives, progress, possibilities and priorities. J Neurol Sci. 2016 Jul 15;366:213-23. doi: 10.1016/j.jns.2016.05.006. Epub 2016 May 6. Review. PMID: 27288810. PubMed Central PMCID: PMC4920548

128. Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler J, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data. J Mass Spectrom. 2016 Jul;51(7):461-75. doi: 10.1002/jms.3782. PMID: 27434804. 129. Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler JA, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data. J Mass Spectrom. 2016 Jul;51(7):ii-iii. doi: 10.1002/jms.3672. PMID: 27434812 130. Aslibekyan S, Vaughan LK, Wiener HW, Hidalgo BA, Lemas DJ, O'Brien DM, Hopkins SE, Stanhope KL, Havel PJ, Thummel KE, Boyer BB, Tiwari HK. Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people. Genes Nutr. 2016 Aug 2;11:23. doi: 10.1186/s12263-016-0538-y. eCollection 2016. PMID: 27579147. PMCID: PMC4971612 131. Lemas DJ, Klimentidis YC, Aslibekyan S, Wiener HW, O'Brien DM, Hopkins SE, Stanhope KL, Havel PJ, Allison DB, Fernandez JR, Tiwari HK, Boyer BB. Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people. Mol Nutr Food Res. 2016 Jul 28. doi: 10.1002/mnfr.201600170. [Epub ahead of print] PMID: 27467133. DOI: 10.1002/mnfr.201600170 132. Day K, Waite LL, Alonso A, Irvin MR, Zhi D, Thibeault KS, Aslibekyan S, Hidalgo B, Borecki IB, Ordovas JM, Arnett DK, Tiwari HK, Absher DM. Heritable DNA Methylation in CD4+ Cells among Complex Families Displays Genetic and Non-Genetic Effects. PLoS One. 2016 Oct 28;11(10):e0165488. doi: 10.1371/journal.pone.0165488. PubMed PMID: 27792787. PMCID: PMC5085095. DOI: 10.1371/journal.pone.0165488 133. Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler J, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its future. J Mass Spectrom. 2016 Aug;51(8):535-548. doi: 10.1002/jms.3780. PMID: 28239968

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134. Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler J, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its future. J Mass Spectrom. 2016 Aug;51(8):ii-iii. doi: 10.1002/jms.3676. PMID: 28239964 135. Balena-Borneman J, Ambalavanan N, Tiwari HK, Griffin RL, Halloran B, Askenazi D. Biomarkers associated with bronchopulmonary dysplasia/mortality in premature infants. Pediatr Res. 2017 Mar;81(3):519-525. doi: 10.1038/pr.2016.259. Epub 2016 Nov 28. PMID: 27893721. DOI: 10.1038/pr.2016.259 136. Aslibekyan S, Do AN, Xu H, Li S, Irvin MR, Zhi D, Tiwari HK, Absher DM, Shuldiner AR, Zhang T, Chen W, Tanner K, Hong C, Mitchell BD, Berenson G, Arnett DK. CPT1A methylation is associated with plasma adiponectin. Nutr Metab Cardiovasc Dis. 2017 Mar;27(3):225-233. doi: 10.1016/j.numecd.2016.11.004. PMID: 28139377 137. Katz DH, Deo RC, Aguilar FG, Selvaraj S, Martinez EE, Beussink-Nelson L, Kim KA, Peng J, Irvin MR, Tiwari H, Rao DC, Arnett DK, Shah SJ. Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection Fraction. J Cardiovasc Transl Res. 2017 Mar 3. doi: 10.1007/s12265-017-9739-z. [Epub ahead of print] PMID: 28258421 138. Adeoye AM, Ovbiagele B, Kolo P, Appiah L, Aje A, Adebayo O, Sarfo F, Akinyemi J, Adekunle G, Agyekum F, Shidali V, Ogah O, Lackland D, Gebregziabher M, Arnett D, Tiwari HK, Akinyemi R, Olagoke OO, Oguntade AS, Olunuga T, Uwanruochi K, Jenkins C, Adadey P, Iheonye H, Owolabi L, Obiako R, Akinjopo S, Armstrong K, Akpalu A, Fakunle A, Saulson R, Aridegbe M, Olowoyo P, Osaigbovo G, Akpalu J, Fawale B, Adebayo P, Arulogun O, Ibinaiye P, Agunloye A, Ishaq N, Wahab K, Akpa O, Adeleye O, Bock-Oruma A, Ogbole G, Melikam S, Yaria J, Ogunjimi L, Salaam A, Sunmonu T, Makanjuola A, Farombi T, Laryea R, Uvere E, Kehinde S, Chukwuonye I, Azuh P, Komolafe M, Akintunde A, Obiabo O, Areo O, Kehinde I, Amusa AG, Owolabi M; SIREN Team as part of H3Africa Consortium..Exploring Overlaps Between the Genomic and Environmental Determinants of LVH and Stroke: A Multicenter Study in West Africa. Glob Heart. 2017 Mar 13. pii: S2211-8160(17)30001-7. doi: 10.1016/j.gheart.2017.01.001. [Epub ahead of print] PMID: 28302552 139. Adeoye AM, Ogah OS, Ovbiagele B, Akinyemi R, Shidali V, Agyekum F, Aje A, Adebayo O, Akinyemi JO, Kolo P, Appiah LT, Iheonye H, Kelechukwu U, Ganiyu A, Olunuga TO, Akpa O, Olagoke OO, Sarfo FS, Wahab K, Olowookere S, Fakunle A, Akpalu A, Adebayo PB, Nkromah K, Yaria J, Ibinaiye P, Ogbole G,

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Olumayowa A, Lakoh S, Calys-Tagoe B, Olowoyo P, Innocent C, Tiwari HK, Arnett D, Godwin O, Ayotunde B, Akpalu J, Obiora O, Joseph O, Omisore A, Jenkins C, Lackland D, Owolabi L, Isah S, Dambatta AH, Komolafe M, Bock-Oruma A, Melikam ES, Imoh LC, Sunmonu T, Gebregziabher M, Olabisi O, Armstrong K, Onyeonoro UU, Sanya E, Agunloye AM, Ogunjimi L, Arulogun O, Farombi TH, Obiabo O, Obiako R, Owolabi M; SIREN Team as part of the H3Africa Consortium..Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans.Glob Heart. 2017 Mar 13. pii: S2211-8160(17)30002-9. doi: 10.1016/j.gheart.2017.01.002. [Epub ahead of print] PMID: 28302557 140. Koo DH, Singh B, Jiang J, Friebe B, Gill BS, Chastain PD, Manne U, Tiwari HK, Singh KK. Single molecule mtDNA fiber FISH for analyzing numtogenesis. Anal Biochem. 2017 Mar 18. pii: S0003-2697(17)30131-8. doi: 10.1016/j.ab.2017.03.015. [Epub ahead of print]. PMID: 28322800 141. Srinivasainagendra V, Sandel MW, Singh B, Sundaresan A, Mooga VP, Bajpai P, Tiwari HK, Singh KK. Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma. Genome Med. 2017 Mar 29;9(1):31. doi: 10.1186/s13073-017-0420-6. PMID: 28356157. PMCID: PMC5370490

142. Owolabi M, Sarfo F, Howard VJ, Irvin MR, Gebregziabher M, Akinyemi R, Bennett A, Armstrong K, Tiwari HK, Akpalu A, Wahab KW, Owolabi L, Fawale B, Komolafe M, Obiako R, Adebayo P, Manly JM, Ogbole G, Melikam E, Laryea R, Saulson R, Jenkins C, Arnett DK, Lackland DT, Ovbiagele B, Howard G; SIREN-REGARDS Collaboration (Stroke Investigative Research and Educational Network–Reasons for Geographic and Racial Differences in Stroke).. Stroke in Indigenous Africans, African Americans, and European Americans: Interplay of Racial and Geographic Factors. Stroke. 2017 Apr 7. pii: STROKEAHA.116.015937. doi: 10.1161/STROKEAHA.116.015937. [Epub ahead of print] PMID: 28389611

143. Aslibekyan S, Irvin MR, Hidalgo BA, Perry RT, Jeyarajah EJ, Garcia E, Shalaurova I, Hopkins PN, Province MA, Tiwari HK, Ordovas JM, Absher DM, Arnett DK. Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). J Nutr Intermed Metab. 2017 Jun;8:1-7. doi: 10.1016/j.jnim.2017.03.002. Epub 2017 Mar 8. PMID: 28439531. PMCID: PMC5400362 [Available on 2018-06-01] 144. Singh KK, Choudhury AR, Tiwari HK. Numtogenesis as a Mechanism for Development of Cancer. Semin Cancer Biol. 2017 May 13. pii: S1044-579X(17)30126-8. doi: 10.1016/j.semcancer.2017.05.003. [Epub ahead of print] Review. PMID: 28511886

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145. Akinyemi R, Arnett DK, Tiwari HK, Ovbiagele B, Sarfo F, Srinivasasainagendra V, Irvin MR, Adeoye A, Perry RT, Akpalu A, Jenkins C, Owolabi L, Obiako R, Wahab K, Sanya E, Komolafe M, Fawale M, Adebayo P, Osaigbovo G, Sunmonu T, Olowoyo P, Chukwuonye I, Obiabo Y, Akpa O, Melikam S, Saulson R, Kalaria R, Ogunniyi A, Owolabi M; SIREN Investigators. Interleukin-6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African Men. J Neurol Sci. 2017 Aug 15;379:229-235. doi: 10.1016/j.jns.2017.05.046. Epub 2017 May 23. PMID: 28716248 146. Yusuf N, Hidalgo B, Irvin MR, Sha J, Zhi D, Tiwari HK, Absher D, Arnett DK, Aslibekyan SW. An epigenome-wide association study of inflammatory response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Pharmacogenomics. 2017 Aug 24. doi: 10.2217/pgs-2017-0037. [Epub ahead of print] PMID: 28835163

147. Tipre M, Turner-Henson A, Tiwari HK, Gohlke J, Chen L, Leader M, Sathiakumar N. Post-Deepwater Horizon Oil Spill Exposure Patterns among Children in Mobile County, Alabama. J Occup Environ Med. 2017 Aug 29. doi: 10.1097/JOM.0000000000001112. [Epub ahead of print] PMID: 28857935

148. Owolabi M, Peprah E, Xu H, Akinyemi R, Tiwari HK, Irvin MR, Wahab KW, Arnett DK, Ovbiagele B. Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities. J Neurol Sci. 2017 Nov 15;382:18-28. doi: 10.1016/j.jns.2017.09.021. Epub 2017 Sep 18. Review. PMID: 29111012 149. Akinyemi R, Tiwari HK, Arnett DK, Ovbiagele B, Irvin MR, Wahab K, Sarfo F, Srinivasasainagendra V, Adeoye A, Perry RT, Akpalu A, Jenkins C, Arulogun O, Gebregziabher M, Owolabi L, Obiako R, Sanya E, Komolafe M, Fawale M, Adebayo P, Osaigbovo G, Sunmonu T, Olowoyo P, Chukwuonye I, Obiabo Y, Onoja A, Akinyemi J, Ogbole G, Melikam S, Saulson R, Owolabi M; SIREN Investigators. APOL1, CDKN2A/CDKN2B, and HDAC9 polymorphisms and small vessel ischemic stroke. Acta Neurol Scand. 2017 Oct 3. doi: 10.1111/ane.12847. [Epub ahead of print] PMID: 28975602 PUBLICATIONS in PEOCEEDINGS: 1. Tiwari HK, Allison DB. IMS sponsored mini-conference on Comparative Genomics, IMS Bulletin, Vol 32, Issue 2, page 12, March/April 2003. 2. Tiwari HK, Holt J, George V, Beasley TM, Amos CI, Allison DB (2004): Power and cost consideration in joint tests of association & linkage for quantitative traits.

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ASA Section on Biometrics Section. The 2004 JSM proceedings: 484-488. 3. George V, Elston RC & Tiwari HK (2004): Two-Stage Designs for Gene-Disease Association Studies. ASA Section on Biometrics Section. The 2004 JSM Proceedings: 338-343. 4. Tiwari HK, Patki A, Musani S, Beasley TM, George V, Allison DB (2005). Incorporating Missing Data Methods in Familial Genetic Data Analyses. ASA Section on Biometrics Section. The 2005 JSM Proceedings: 402-406. 5. Tiwari HK, Patki A, Padilla M, Beasley TM, Allison DB (2006). Within-cluster Resampling Methods in Association Analysis with Pedigree Data ASA Section on Biometrics Section. The 2006 JSM Proceedings. 6. Vazquez AI, Wiener HW, Shrestha S, Tiwari HK, Campos GDL, Integration of Multi-Layer Omic Data for Prediction of Disease Risk, Proceedings, 10th World Congress of Genetics Applied to Livestock Production 1-6, Aug 19, 2014. BOOK CHAPTERS: 1. Schork NJ, Fallin D, Tiwari HK, Schork MA (2001): Pharmicogenetics. Handbook of statistical genetics. Balding DJ et al. (Eds). pp 741-764. John Wiley & Sons, Ltd, NY. 2. Tiwari HK. (2001): Sequence analysis. Elston RC et al (Eds). Encyclopedia of Human Genetics and Genetic Epidemiology. John Wiley & Sons, Ltd, NY. 3. Tiwari HK, T. Beasley M, George V, Allison DB (2007). Multifactorial Inheritance and Complex Diseases. Emery and Rimoin’s Principles and Practice of Medical Genetics, 5th edition, Rimoin, Connor, Pyeritz, and Korf (Eds). Vol 1, pp299-306, Elsevier Ltd., Philadelphia, PA. 4. Redden DT, Divers J, Vaughan LK, Padilla MA, Musani S, Tiwari HK, Allison DB (2007). Overview of Genetic Studies in Polygenic Obesity and Methodological Challenges (chapter 6). In K. Clement & T. I. A. Sorensen (Eds.), Obesity: Genomics and Pos genomics (pp. 229-247). NY: Informa Healthcare. 5. Barnholtz-Sloan J, Tiwari HK. Population Genetics. In Bioinformatics for Systems Biology, Stephen Krawetz (editor), second edition, Humana Press. 2009, pages: 163-180. ISBN: 978-1-934115-02-2 6. Wojczynski MK, Tiwari HK. Definition of phenotype. In Genetic Dissection of Complex Traits, Rao and Gu (Editors), 2nd Edition, Elsevier, Boston, chapter 4, 2008, pages 75-105. ISBN: 978-0-12-373883-7. 7. Padilla, M. A., Irvin, M. R., & Tiwari, H. K. (2011). Gene-environment

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Interactions: Gene-environment interactions in human traits. In Nriagu (Ed.), Encyclopedia on Environmental Health. Elsevier Science. 8. Duarte, C. W., Vaughan, L. K., Mark Beasley, T., & Tiwari, H. K. (2014). Multifactorial Inheritance and Complex Diseases. In Reference Module in Biomedical Research. doi:10.1016/B978-0-12-801238-3.05485-4

9. Duarte, C. W., Vaughan, L. K., Beasley, T. M., & Tiwari, H. K. (2013). Multifactorial Inheritance and Complex Diseases. In Emery and Rimoin's Principles and Practice of Medical Genetics (pp. 1-15). doi:10.1016/B978-0-12-383834-6.00014-8 PUBLISHED ABSTRACTS: 1. Tiwari HK, Elston RC (1997): Restrictions on the components of genetic variance. Genet Epidemiol 14:540-541. 2. Tiwari HK, George V, Schork NJ (1997): Randomly ascertained family-based candidate locus analysis of quantitative traits: efficiency and modeling considerations. Am J Hum Genet A213. 3. George V, Tiwari HK, Elston RC (1998): An alternative test for linkage between a marker locus and a quantitative traits. Genet Epidemiol 15:525. 4. Tiwari HK, George V, Schork NJ (1998): Power and sample size consideration for detecting epistasis. Genet Epidemiol 15:532. 5. George V, Tiwari HK (1999): A regression-based transmission/disequilibrium test for binary traits using logit link function. Genet Epidemiol 17:192. 6. Tiwari HK, Elston RC (1999): A new explicit algorithm to calculate identity by descent probabilities for pairs of relatives with respect to two linked loci. Genet Epidemiol 17:216. 7. Tiwari HK, George V, Elston RC (1999): A two-stage test of transmission/disequilibrium for quantitative traits in pedigree data. Am J Hum Genet.A449. 8. Tiwari HK, Schork NJ (2000): A general framework for comparing the power of mean effects and variance-component linear models for quantitative group comparisons. Am J Hum Genet 67 : 218. 9. Thiel BA, Tiwari HK, Fallin D, Schork NJ (2000): The effects of misspecification of marker allele frequencies in affected sibpair linkage analysis.

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Am J Hum Genet 67 : 218. 10. George V, Tiwari HK, Elston RC (2000): Evaluating the power and validity of a two-stage TDT for quantitative traits in pedigree data. Genet Epidemiol 19: 249. 11. Nath SK, Chakravarti A, Cooper R, Lewis S, Lynn A, Tiwari HK, Weder A, Schork NJ (2000): Familial resemblance of some intermediate phenotypes of hypertension in two U.S. populations. Genet Epidemiol 19: 264. 12. Tiwari HK, Thiel BA, Fallin D, Schork NJ (2000): The effect of allele frequency misspecification on affected sibpair linkage studies. Genet Epidemiol 19: 274. 13. Gass J, Valiathan M, Tiwari HK, Hans MG(2001): The Heritability of Maxillary Midline Diastemas. Abstract number 435. Journal of Dent Res 80: 90. 14. Stein CM, Mugerwa R, Peters P, Elner J, Elston RC, Tiwari HK, Whalen CC (2001): Heritability analysis of intermediate phenotypes of tuberculosis. Genet Epidemiol 21:177. 15. Gray-McGuire C, Kelly J, Tiwari HK, Harley JB (2001): Fine scale multipoint linkage mapping in human systemic lupus erythematosus: Isolation of linkage effect to 8cM region on chromosome 4p16. Genet Epidemiol 21:156. 16. Tiwari HK, Chen CH, George V (2001): A regression-based TDT for mapping quantitative trait loci with multiple alleles. Genet Epidemiol 21:179. 17. Gray-McGuire C, Kelly J, Tiwari HK, Harley JB (2001): Linkage and linkage disequilibrium fine scale of 16cM region on chromosome 4p16-15.2 in pedigrees multiplex for human systemic lupus erythematosus. ASHG 69:520. 18. George V, Chen CH, Tiwari HK (2001): A regression-based haplotype TDT for quantitative traits in pedigree data. ASHG 69: 521. 19. Stein CM, Mugerwa R, Peters P, Elner J, Elston RC, Tiwari HK, Whalen CC (2001): Genetic transmission of tuberculosis-related traits. ASHG 69: 405. 20. Kwong J, Valiathan M, Tiwari HK, Elston RC, Hans MG (2002): Patterns in congenital hypodontia. Journal of Dent Res. 21. Moullas A, Valiathan M, Tiwari HK, Elston RC (2002): The etiology of palatally displaced canines; the evidence examined. Journal of Dent Res. 22. Tiwari HK, George V , Elston RC (2002): Validity of two-stage QTDT for small samples. Genet Epidemiol 23: 134.

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23. Tiwari HK, Beasley M, Leibel R, Allison DB (2003): Distributional properties of composite measure of adiposity. Obesity Research 11 (sep):497_P 24. Gibson AW, Wu J, Edberg JC, Tiwari HK, Kimberly RP. Single Nucleotide Polymorphisms in the Fc Receptor Homology (FcHR) (2003) Arthritis Rheum. 49 (Suppl. 9); 1004. 25. Bridges SL, Tiwari, HK, Hughes LB, Criswell LA, Seldin MF. (2003): Haplotypes defined by single nucleotide polymorphisms (SNPs) and microsattelites in the lymphotoxin-a (LTA)/tumor necrosis factor (TNF) region and their association with HLA DRB1 alleles in early rheumatoid arthritis. Arthritis Rheum. 49 (Suppl. 9); 1780. 26. Matsuoka N, Deng L, Johnson SB, Gregersen PK, Allision DB, Tiwari HK, Leibel RL, Chung WK (2003). A GHRELIN Promoter Sequence Variant is Associated with BMI in Caucasian Adults. Diabetes 52 (suppl 1): A397 abstract number 1725-P 27. Matsuoka N, Deng L, Johnson SB, Gregersen PK, Allision DB, Tiwari HK, Leibel RL, Chung WK (2004). Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasians and African Americans. American Diabetes. Diabetes, 53(Suppl 2), 1737-P. A414. 28. Matsuoka N, Deng L, Johnson SB, Gregersen PK, Allision DB, Tiwari HK, Leibel RL, Chung WK (2004). A GHRELIN promoter sequence variant is associated with BMI in Caucasian adults. Diabetes, 52 (Suppl 1), A397. 29. Matsuoka N, Patki A, Tiwari HK, Luke A, Johnson S, Gregersen P, Allision DB,Leibel RL, Chung WK (2005). Association of +2138InsCAGACC in MC3R with obesity in African-Americans. Obesity Reserch. NAASO’s 2005 Annual Scientific Meeting. 613-P. 30. Boyer B, Chung WK, Patki A, Matsuoka N, Goropashnaya A, Allison DB, Leibel RL, Tiwari HK. Obesity candidate gene association study Yup’ik Eskimos indicates a role for several hypothalamic genes involved in the control of energy homeostasis. Supplement to Obesity. Volume 14, September 2006. 149-OR, A46. 31. Tiwari HK, Patki A, Matsuoka N, Musani S, Boyer B, Allison DB, Leibel RL, Chung WK. Case-Control association study of candidate genes of energy homeostasis. Supplement to Obesity. Volume 14, September 2006. 152-OR, A47. 32. Musani S, Patki A, Matsuoka N, Loraine A, Tiwari HK, Allison DB, Leibel RL, Chung WK. Evidence for epistasis from SNP x SNP interactions of 30 candidate genes for human obesity in a Caucasian sample. Supplement to Obesity. Volume

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14, September 2006. 626-P, A198. 33. D. Morrison, S. L. Bridges, Jr., A. O. Westfall, H. K. Tiwari, G. S. Alarcón, D. L. Conn, B. L. Jonas, L. F. Callahan, E. A. Smith, G. S. Gilkeson, G. Howard, D. van der Heijde, L. W. Moreland, L. B. Hughes. Novel Association Of A Functional Single Nucleotide Polymorphism In The BTNL2 Gene With Susceptibility To Rheumatoid Arthritis And Baseline Radiographic Severity In African-Americans Independent Of HLA DRB1: Results From The CLEAR Registry. ACR 2006. 34. P. Dechanuwong, L. B. Hughes, A. O. Westfall, H. K. Tiwari, D. van der Heijde, D. L. Conn, B. L. Jonas, L. F. Callahan, E. A. Smith, G. S. Gilkeson, L. W. Moreland, S. L. Bridges, Jr. The Role of Single Nucleotide Polymorphisms (SNPs) in the Osteoprotegerin (OPG) and Serum OPG Levels in African-Americans (A-A) with Rheumatoid Arthritis (RA): Results from the CLEAR Registry. ACR 2006. 35. L. B. Hughes, D. Morrison, A. O. Westfall, H. K. Tiwari, G. S. Alarcon, D. L. Conn, B. L. Jonas, L. F. Callahan, E. A. Smith, G. S. Gilkeson, G. Howard, D. van der Heijde, L. A. Parrish, V. M. Holers, L. W. Moreland, S. L. Bridges, Jr. Genetic and Non-Genetic Factors Associated with Baseline Radiographic Severity in African-Americans with Early Rheumatoid Arthritis: Results from the CLEAR Registry. ACR 2006. 36. L. B. Hughes, D. Morrison, P. Dechanuwong, A. O. Westfall, H. K. Tiwari, G. S. Alarcon, D. L. Conn, B. L. Jonas, L. F. Callahan, E. A. Smith, G. S. Gilkeson, G. Howard, L. W. Moreland, S. L. Bridges, Jr. Genetic and Non-Genetic Risk Factors Associated with Rheumatoid Arthritis Susceptibility in African-Americans: Results From The CLEAR Registry. ACR 2006.

37. Padilla, M. A., Divers, J., Vaughan, L. K., Allison, D. B., & Tiwari, H. K. (2007). Multiple Imputation to Correct for Measurement Error in Genetic Structured Association Testing. Presented at the American Society of Human Genetics 57th Annual Meeting, San Diego, CA.

38. Boyer, B.B., Chung, W.K., Patki, A., Matsuoka, N., Musani, S.K.,

Goropashnaya, A., Allison, D.B., Leibel, R.L. and Tiwari, H.K. Analysis of interactions among 30 candidate genes implicated in the control of energy homeostasis in two divergent populations. In “Obesity: Peripheral and central pathways regulating energy homeostasis” Held on January 14 - 19, 2007 Keystone Resort - Keystone, Colorado USA.

39. Musani, S.K., Tiwari, H.K., Leibel, R.L., Allison, D.B., Chung, W.K. Search

for Epistatic Interactions among 9 Pre-selected Known Obesity Candidate Genes. Presented at the NAASO Annual 2007 Scientific Meeting, New Orleans, LA, October 20-24th, 2007.

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40. Musani, S.K., Tiwari, H.K., Leibel, R.L., Allison, D.B., Chung, W.K. Interaction between GLP1R and BBS8 is associated with obesity in a European American sample population. Presentation at the NMRI Southern Region at the Holiday Inn Select, Atlanta Capitol Conference Center in Atlanta, GA, October 3-4 2007

41. Musani, S.K., Patki, A., & Tiwari, H.K. Performance of statistical procedures

for the detection of interlocus interactions in genome-wide association studies: Statistical power and type I error rates. (2007) Presentation at International Biometric Society, ENAR Spring Meeting, March 11-14, 2007. Atlanta, Georgia, Section 72. 43. Padilla MA, Wiener H, Rubin D, Tiwari HK. Measurement Error Correction via Multiple Imputations. ENAR Meeting, International Biometric Society, March 16-19, 2008. 44. Padilla MA, Divers J, Tiwari HK. Linear Model Covariate Measurement Error Correction via Multiple Imputations, ENAR Meeting, International Biometric Society, March 16-19, 2008. 45. Pasker R, Dickson M, Wiener H, Jeannet AM, O’Brien D, Tiwari HK, Boyer BB. Gene by environment interactions between four candidate genes for obesity and omega-3 polyunsaturated fatty acids (PUFAs) in Yup’ik Eskimos. American Society of Human Genetics, Nov 11-15,2008, Philadelphia, PA. 46. Kraja AT, Park YM, Borecki IB, Tiwari HK, Pankow JS, Hunt SC, Brockel U, Arnett DK, Rao DC, Province MA. Metabolic syndrome gene network and its association with factors of metabolic syndrome. American Society of Human Genetics, Nov 11-15, 2008, Philadelphia, PA. 47. Tiwari HK, Birkner T, Moondan A, Zhang S, Page GP, Patki A, Allison DB. Accurate and Flexible Power Calculations on the Spot: Applications to Genomic Research. American Society of Human Genetics, Nov 11-15, 2008, Philadelphia, PA. 48. Wineinger NE, Pajewski N, Kennedy R, Wojcznski MK, Hunt SC, Gu CC, Broeckel U, Rao DC, Arnett DK, Tiwari HK. Genome wide characterization of CNVs in African Americans from HyperGEN. 18th Annual Meeting of International Genetic Epidemiology Society, October 18-20, 2009, Kahuku, Hawaii. 49. Wojcznski MK, Absher DM, Tiwari HK, Kabagambe EK, Arnett DK. Epigenetic associations with triglyceride response to a high-fat meal: A pilot study of the genetics of lipid lowering drugs and diet network (GOLDN) study. 59th Annual Meeting of American Society of Human Genetics, October 20-24, 2009 Honolulu, Hawaii

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50. Boyer B, Pasker R, Irvin M, Weiner H, O’Brien D, Jeannet M, Stanhope K, Havel P, Mohatt G, Tiwari HK. ADIIPOQ gene variation is associated with plasma adiponectin and HDL cholesterol in Yup’ik Eskimos: The CANHR study. 59th Annual Meeting of American Society of Human Genetics, October 20-24, 2009, Honolulu, Hawaii. 51. Pajewski N, Srinivassasainagendra V, Parker S, Kaslow R, Tiwari HK, McKinney B. ReliefF Methods for Gene Gene Interaction: Prioritizing SNPs for quantitative trait interaction testing. 59th Annual Meeting of American Society of Human Genetics, October 20-24, 2009, Honolulu, Hawaii 52. Wojczynski MK, Hunt SC, Patki A, Vaughan LK, Rao DC, Broeckel U, Tiwari HK, Arnett DK. GWAS of Reactive Blood Pressure Phenotypes Involving Central Nervous System Stimulation: the HyperGEN Study. NHLBI Cardiovascular Epidemiology, Biostatistics and Behavioral Medicine Trainee Session at the AHA 49th Cardiovascular Disease Epidemiology and Prevention Annual Conference. Palm Harbor, FL, March 11-14, 2009. 53. Tiwari HK, Patki A, Allison DB. Within-Cluster Resampling (Multiple Outputation) for analysis of Family Data: Ready for Prime-Time? ENAR 2009, San Antonio. 54. You Z, Aban I, Kabagambe EK, Tiwari HK, Buller DB, Voeks JH, Cutter GR. Power and sample size of cluster randomized trials with unequal cluster size. Society for Clinical Trials 30th Annual Meeting (May 3-6, 2009). 55. Kennedy R, Tiwari HK. Multiple Imputation for Missing Values in Microarray Data, July 31-August 5, 2010, Joint Statistical Meeting, British Columbia, Canada. 56. Wineinger N, Broeckel U, Rao DC, Devereux RB, Patki A, Arnett DK, Tiwari HK. Genome-wide joint SNP and CNV analysis of aortic root diameter: the HyperGEN study. American Heart Association Joint Conference – 50th Cardiovascular Disease Epidemiology and Prevention – and – Nutrition, Physical Activity and Metabolism – 2010. San Francisco, California. 57. Irvin, M. R., Lynch, A. I., Kabagambe, E. K., Tiwari, H. K., Barzilay, J. I., Eckfeldt, J., . . . Arnett, D. K. (2010). Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. Poster session presented at the meeting of American Heart Association Cardiovascular Disease Epidemiology and Prevention Conference.

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58. Irvin, M. R., Wineinger, N., Pajewski, N. M., Kabagambe, E. K., Gu, C. C., Pankow, J., . . . Arnett, D. K. (2010). Genome wide detection of allele specific copy number variation associated with diabetes related traits in African Americans from the HyperGEN Study. Poster session presented at the meeting of HudsonAlpha Spring Symposium.

59. Wineinger NE, Pajewski NM, Tiwari HK. A new method to assess linkage disequilibrium between SNPs and CNVs. Keystone Symposium on Structural Variation in the Genome. January 8-13, 2011, Steamboat Springs, Colorado. 60. Wei Zhao, Nathan E. Wineinger, Hemant K. Tiwari, Thomas M. Moseley, Ulrich Broeckel, Donna K. Arnett, Sharon L. R. Kardia, Edmond K. Kabagambe, Yan V. Sun. Copy number variations associated with obesity related traits in African Americans. The 12th International Meeting on Human Genome Variation and Complex Genome Analysis 2011 at Berkeley, CA (Sept 8-10th, 2011). 61. Wood A.C, Kabagambe, E.K., Borecki, I.E., Tiwari, H.K., Ordovas, J., & Arnett, D. K.,“An association between the LRP-1 I10701 polymorphism and body mass index in humans may be modified by an interaction with ApoE genotypes” American Heart Association Scientific Sessions 2011, Orlando, Florida, USA; Nov 12th-16th 2011. 62. Wood A.C, Glasser, S., Kabagambe, E.K., Borecki, I.E., Tiwari, H.K., Tsai, M., Hopkins, P., Ordovas, J., Arnett, D.A., “Lipoprotein Lipase S447X polymorphism associates with VLDL, LDL and HDL diameter clustering” American Diabetes Association 71st Scientific Sessions, San Diego, California, USA; June 24-28th 2011. 63. Irvin MR, Wood AC, Vaughn LK, Kabagambe EK, Sha J, Tiwari HK, Borecki IB, Ordovas JM, Arnett DK. Genetics of Insulin Response to Fenofibrate in the GOLDN Study. Poster Presentation at AHA Scientific Sessions. Nov 12-15 2011, Orlando FL. 64. Irvin MR, Kabagambe EK, Zhang Q, Sha J, Tiwari HK, Borecki IB, Province MA, Shimmim LC, Hixson JE, and Arnett DK.. Rare PPARa variants and extreme response to fenofibrate in the GOLDN Study. Poster Presentation at the 51th annual American Heart Association Cardiovascular Disease Epidemiology and Prevention Conference. March 23-25th 2011, Atlanta, GA. 65. Donna K. Arnett, Ingrid B. Borecki, Marguerite R. Irvin, Hemant K. Tiwari, Robert J. Straka, Jose M. Ordovas. Genome-wide association study of lipid response to fenofibrate treatment in the GOLDN Study. Cardiovascular Disease Epidemiology and Prevention 2012 Scientific Sessions, San Diego, California, USA; March 13-16th 2012. 66. Frazier-Wood, A.C, Manichaikul A., Aslibekyan, S., Borecki, I.B., Goff, D.C., Hopkins, P.M., Lai, C.M., Ordovas , J.M., Post, W.S., Rich, S.S., Sale, M.M.,

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Szklo, M., Siscovick, D., Straka, R.J., Tiwari, H.K., Tsai, M.Y., Rotter, J.I., Arnett, D.K. Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Beyond the Genome, Boston, Massachusetts, USA; September 2012 67. Frazier-Wood A.C. Aslibekyan, S., Straka, R.J., Borecki, I. B., Tiwari, H.K., Tsai, M.Y. Hopkins, P.N., Ordovas, J.M. Arnett, D.K. Genome-wide Association Study suggests that Inflammation and Insulin Regulation Pathways may mediate Lipoprotein Diameter Response to Fenofibrate. Nutrition, Physical Activity and Metabolism / Cardiovascular Disease Epidemiology and Prevention 2012 Scientific Sessions, San Diego, California, USA; March 13-16th 2012. 68. Frazier-Wood, AC, Borecki, IB, Feitosa, M, Hopkins, PN, Ordovas, JM, Tiwari, HK., & Arnett, DK., Screen time is associated with changes in lipoprotein profiles, and this effect is not mediated by BMI, but by insulin resistance. The Obesity Society Annual Meeting, San Antonio, Texas, USA; September 2012 69. Frazier-Wood, A.C., Aslibekyan, S., Straka, R.J., Borecki, I. B., Tiwari, H.K., Tsai, M.Y. Hopkins, P.N., Ordovas, J.M. Arnett, D.K. Genome-wide Association Study suggests that Inflammation and Insulin Regulation Pathways may mediate Lipoprotein Diameter Response to Fenofibrate. Nutrition, Physical Activity and Metabolism / Cardiovascular Disease Epidemiology and Prevention 2012 Scientific Sessions, Atlanta, Georgia, USA; March 2012 70. Aslibekyan S, Kabagambe E, Irvin MR, Borecki IB, Tiwari HK, Lai CQ, Tsai MY, Hopkins PN, Ordovas JM, Shen J, Straka RJ, Arnett DK. A genome-wide association study of inflammatory biomarkers before and after fenofibrate treatment in Genetics of Lipid Lowering and Diet Network (GOLDN) participants. Nutrition, Physical Activity and Metabolism / Cardiovascular Disease Epidemiology and Prevention 2012 Scientific Sessions, Atlanta, Georgia, USA; March 2012. 71. Aslibekyan, S., Frazier-Wood, A. C., Irvin, M. R., Straka, R. J., Borecki, I. B., Tiwari, H. K., . . . Arnett, D. K. (2012). APOA1, CETP, and CILP2 variants modify the lipid response to fenofibrate: Genetics of Lipid Lowering and Diet Network.. Poster session presented at the meeting of American Heart Association ATVB Scientific Sessions. 72. Absher D, Waite L, Tiwari HK, Arnett D. Genome-wide estimation of DNA methylation heritability in CD4+ T-cells from 80 families. Absher D, Waite L, Tiwari H, Arnett D. American Society of Human Genetics Annual Meeting, San Francisco, CA Nov 2012. 73. Arnett DK, Borecki IB, Irvin MR, Tiwari HK, Straka RJ, Ordovas JM. Genome-Wide Association Study of Lipid Response to Fenofibrate Treatment in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN) Study. Nutrition,

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Physical Activity and Metabolism / Cardiovascular Disease Epidemiology and Prevention 2012 Scientific Sessions, Atlanta, Georgia, USA; March 2012. 74. Aslibekyan, S., Frazier-Wood, A. C., Absher, D. M., Sha, J., Zhi, D., Kabagambe, E. K., Straka, R. J., Tiwari, H. K., Tsai, M. Y., Hopkins, P. N. et al. (2013). Epigenome-wide study of epigenetic inflammation.. Poster session presented at the meeting of American Heart Association EPI/NPAM Scientific Sessions. 75. Hidalgo, B. A., Irvin, M. R., Sha, J., Kabagambe, E., Zhi, D., Aslibekyan, S., Absher D. M., Tiwari, H. K., Arnett, D. K. (2013). Epigenetics of Fasting Insulin and Glucose Concentrations. Poster session presented at the meeting of American Diabetes Association Scientific Sessions. 76. Aslibekyan, S., Irvin, M. R., Sha, J., Hidalgo, B., Tiwari, H. K., Zhi, D., Ordovas J. M. , Absher D. M., Arnett, D. K. (2014). Epigenome-wide study of erythrocyte fatty acids in the Genetics of Lowering Drugs and Diet Network.. Poster session presented at the meeting of American Heart Association EPI/NPAM Scientific Sessions. 77. Hidalgo, B. A., Irvin, M. R., Aslibekyan, S., Sha, J., Zhi, D., Ordovas, J. M., Absher D. M., Tiwari, H. K., Arnett, D. K. (2014). Epigenome-wide study of lipid and inflammatory marker response to fenofibrate in the Genetics of Lowering Drugs and Diet Network study.. Poster session presented at the meeting of American Heart Association EPI/NPAM Scientific Sessions. 78. Aslibekyan, S., Hidalgo, B., Irvin, M. R., Sha, J., Tiwari, H. K., Zhi, D., Ordovas J. M. , Absher D. M. , Arnett, D. K. (2014). Epigenome-wide study of plasma adiponectin in the GOLDN study.. Poster session presented at the meeting of Society for Epidemiologic Research Annual Meeting. 79. Tiwari, HK, Patki, A., Cofield, S. S., Gustafson, T., Lublin, F. D., Wolinsky, J. S., & Cutter, G. R. (2015). Biomarkers and Relapse in CombiRx. Poster session presented at the meeting of The American Academy of Neurology's 67th AAN Annual Meeting. 80. Aslibekyan, S., Frazier-Wood, A. C., Hidalgo, B. A., Sha, J., Jeyarajah, E., Garcia, I., Tiwari, H. K., Arnett, D. K. (2015). Trimethylamine-N-Oxide (TMAO), diet, and inflammation.. Poster session presented at the meeting of Society for Epidemiologic Research Annual Meeting. 81. Aslibekyan, S., Irvin, M. R., Hidalgo, B. A., Jeyarajah, E., Shalaurova, I., Garcia, I., Tiwari H. K., Absher D. M., Arnett, D. K. (2015). Integrating null data: a family-based (epi)genetic study of TMAO.. Poster session presented at the meeting of International Genetic Epidemiology Society Annual Meeting.

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82. Tiwari, HK, Patki, A., Cofield, S. S., Gustafson, T., Duggan, D., Jacobson, S., . . . Cutter, G. R. (2015). GWAS on relapse outcomes in CombiRx trial. Poster session presented at the meeting of 31st Congress of the European Committee For Treatment and Research in Multiple Sclerosis (ECTRIMS).