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CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400 Office Fax : 312-908-8885 E-maih [email protected] DATE OF BIRTH: October 20, 1956 PLACE OF BIRTH: Billings, Montana CITIZENSHIP: United States EDUCATION: 1976-1980 1980-1984 EXPERIENCE: 9/00-Present 11/94-8/00 1993-11/94 1991-1993 1992 1990-1991 1987 - 1990 1987 1984-1987 1980-1984 B.S. Chemistry, University of Missouri, "with distinction" M.D. St. Louis University School of Medicine, "Cum Laude" Chief, Division of Immunotherapy, Tenured Associate Professor, Northwestern University Medical School, Chicago, IL. Director, AIIogeneic Bone Marrow Transplantation, Assistant Professor, Northwestern University, Chicago, IL. Clinical Fellow, Bone Marrow Transplantation Unit, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland. Clinical Fellow, Clinical Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Visiting Fellow, Bone Marrow Transplantation, Fred Hutchinson Cancer Center, Seattle, Washington {3 months) and Johns Hopkins Hospital, Bone Marrow Transplant Unit, Baltimore, Maryland (2 months). Clinical Fellow, Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Biotechnology Training Fellow, Laboratory of Experimental Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda Maryland. Chief Resident, Medicine, Baylor College of Medicine, Houston Texas Resident, Baylor Clinical Investigator Pathway, Baylor College of Medicine, Houston, Texas. Medical School, Saint Louis University

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Page 1: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

CURRICULUM VITAE

Richard K. Burt, M.D.680 North Lake Shore Drive, #2400 TowerChicago, IL. 60611Home Phone: 312-266-0341Office Phone: 312-908-5400Office Fax : 312-908-8885E-maih [email protected]

DATE OF BIRTH: October 20, 1956

PLACE OF BIRTH: Billings, Montana

CITIZENSHIP: United States

EDUCATION:

1976-19801980-1984

EXPERIENCE:

9/00-Present

11/94-8/00

1993-11/94

1991-1993

1992

1990-1991

1987 - 1990

1987

1984-1987

1980-1984

B.S. Chemistry, University of Missouri, "with distinction"M.D. St. Louis University School of Medicine, "Cum Laude"

Chief, Division of Immunotherapy, Tenured Associate Professor, Northwestern University MedicalSchool, Chicago, IL.

Director, AIIogeneic Bone Marrow Transplantation, Assistant Professor, Northwestern University,Chicago, IL.

Clinical Fellow, Bone Marrow Transplantation Unit, National Heart, Lung and Blood Institute,National Institutes of Health, Bethesda, Maryland.

Clinical Fellow, Clinical Hematology Branch, National Heart, Lung and Blood Institute, NationalInstitutes of Health, Bethesda, Maryland

Visiting Fellow, Bone Marrow Transplantation, Fred Hutchinson Cancer Center, Seattle, Washington{3 months) and Johns HopkinsHospital, Bone Marrow Transplant Unit, Baltimore, Maryland (2 months).

Clinical Fellow, Medical Oncology Branch, National Cancer Institute, National Institutes of Health,Bethesda, Maryland.

Biotechnology Training Fellow, Laboratory of Experimental Carcinogenesis, National CancerInstitute, National Institutes of Health, Bethesda Maryland.

Chief Resident, Medicine, Baylor College of Medicine, Houston Texas

Resident, Baylor Clinical Investigator Pathway, Baylor College of Medicine, Houston, Texas.

Medical School, Saint Louis University

Page 2: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

1981

1981

1980

Unclassified Resident (summer), St. Louis State Mental Hospital.

Teaching Assistant (summer), Department of Anatomy, St. Louis University School of Medicine

Research assistant, Veterans Administration Hospital, Kansas City, Missouri

EDUCATIONAL HONORS:

University of Missouri, Kansas City, MissouriDean’s Honor RollUniversity Scholar AwardPhi-Kappa-Phi Honor Society (executive board student representative)Department of Chemistry, Outstanding Graduate AwardGraduated Magna Cum Laude, GPA 3.98

St. Louis Medical SchoolAmerican Cancer Society Medical Student Grant for summer internship and research on

childhood cancers at Cardinal Glennon Memorial Hospital for ChildrenDepartment of Microbiology Outstanding Medical Student Award,Graduated Cum Laude

OTHER HONORS:

Compassionate Care Physician Award 1999, Robert H Lurie Cancer CenterLeukemia Society of America Scholar, 1999-2004Lupus Foundation of America Fidelitas Award 2000Scientific American Magazine SA-50 for 2006. Recognized as one of the 50 top people

worldwide in 2006 for advancing the future of Humanity.

EXAMINATIONS/CE RTIFICATIONS:

1992 Hematology Boards - Board Eligible1992 Medical Oncology Boards: (National Rank -Top 3 percentile)1987 American Boards of Internal Medicine (National Rank-Top 5 percentile)1985 National Medical Boards, Part Ill - 670 (National Rank -Top 5 percentile)1988 National Medical Boards, Part II- 680 (National Rank-Top 5 percentile)1982 National Medical Boards, Part I - 670 (National Rank -Top 5 percentile)

RESEARCH GRANT AWARDS:

2002 ~200,000

2002 S150,000.00

2002 $101,750.00

Broad Foundation Grant "Immune ablation and stem cell transplant in Crohn’sdisease" IBD-0004

Cumming Foundation for Medical Research. "Stem cell therapy for MultipleSclerosis"

BMRP Proposal No. IBD-0004 Inflammatory bowel disease grant, Broad MedicalResearch Program. The Eli and Edythe Broad Foundation "Immune ablation andperipheral stem cell support in patients with severe Crohn’s Disease"

2

Page 3: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

1999-2007 $ 9,185,002.00

1999 $105,000.00

1998-2003 $350,000.00

1998 $75,000.00

1997-1999 $200,000.00

1997 ~i0%000.00

1996 $33,000.00

1995 $30,000.00

1994 $250,000.00

1988 $30,000.00

National Institutes of Health, National Institute of Allergy and Infectious Disease,N01-A1-95387,

Amgen investigator award for augmenting bone marrow with CD34 enrichedPBSC in patients undergoing allogeneic transplantation for hematologicmalignancies

Leukemia Society Of America Scholar (LSA Scholar)

Amgen investigator award for hematopoietic stem cell transplantation ofautoimmune diseases

Translational Research Award, Leukemia Society of America. Remission Inductionof Relapsed Leukemia after AIIogeneic BMT Using HSTK Transduced DonorLymphocytes.

Excellence in Academic Medicine (EAM)

American Cancer Society, Remission Induction of Leukemia with HSTKTransduced Lymphocyte

National Multiple Sclerosis Society; Syngeneic bone marrow transplantation inEAE.

Liedske Foundation: Stem cell therapy for multiple sclerosis

Roderick Duncan Research Fund, "Effect of PCO2 on coronary sinus blood flowand myocardial infant size.

SOCIETIES

American Medical AssociationAmerican Association for the Advancement of ScienceAmerican Society for Blood and Marrow Transplantation

MILITARY SERVICE:

1991-1994 Lieutenant Commander, active duty, Public Health Service

HOBBLES

Pilot, single engine landWeight liftingJogging

NIH STUDY SECTIONSSpecial Emphasis Panel (SEP) NIAID, NIH

3

Page 4: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

COMMITI’EE CHAIR:

1997- 2002IBMTR/ABMTRChair on Transplantation for Autoimmune Diseases

JOURNAL EDITORIAL BOARDS:

Bone Marrow Transplantation, 1998-Present.Regenerative Medicine, 2005--presentCurrent Stem Cell Research and Therapy 2005--present

JOURNAL REFEREE1. Blood2. Biotechnology3. The Lancet4. Bone Marrow Transplantation5. Gra~t6. Arthritis and Rheumatism7. Nature Medicine8. Stem cells

TEACHING EXPERIENCE

1987

1994 to present

1994 to 1999

1996 to present

1996 to present

1998 to present

1996 to present

2001 to present

Chief resident, Baylor College of Medicine

Daily rounds with house staff, fellows, and medical students on inpatient care

Weekly Firm conference attending

Weekly clinical teaching conference for all house staff, students, fellows, and faculty

Weekly laboratory research conference with post doctorates, technicians, students

Participation in core house staff lectures

Supervisor for summer medical student summer research project

Director, FellowShip program, Northwestern University, Department of Medicine, Divisionof Immunotherapy

4

Page 5: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

BOOKS:

1. Butt RK, Deeg, J., Santos, G, Editors. On Call in Bone Marrow Transplantation. Chapman Hall, New York, New York,1996.

2. Butt RK, Associate Editor. Year Book of Oncolol~y. Editor in Chief, Joseph Simone, Mosby-Year-Book, Inc. St LouisMissouri, 1996.

3. Butt RK, Brush M, Editors. AIIol~eneic Hematopoietic Stem Cell Transplantation. Kluwer Academic Publishers.Norwell, Massachusetts 1999

4. Butt RK, Marmont AM, Editors. Stem cell therapy of autoimmune diseases--Landes Biosciences(www.landesbioscience.com), Georgetown, Texas, 2004

CHAPTERS:

Thorgeirsson, SS, GarField, SH, Huber, BE, and Butt, RK: Acquisition of multidru[ resistance in chemical hepato-carcinogenesis. In Estabrook, R.W., Lindenlaub, E., Oesch, F. and de Weck, A.L. (eds.): Toxicological andImmunological Aspects of Drug Metabolism and Environmental Chemicals, Symposia Medical Hoechst 22. F.K.Schattauer Verlag, Stuttgart, Germany, 1988 pp. 367-377.

2. Butt RK, Wilson W, R.G. Landes Bioscience Publisher. Conditioning regimens. In On Call in Bone MarrowTransplantation. Chapman Hall, New York, New York, 1996. Chapter 4.1, pp. 94-109.

3. Butt RK, Rowlings P, Santos, G. BMT for adult acute lymphoblastic leukemia (ALL), In On Call in Bone MarrowTransplantation, Chapman Hall, New York, New York, 1996, Chapter 6.3, pp 173-188.

4. Butt RK, Rowlings, P, Santos,G: BMT for acute myeloblastic leukemia (AML). In On Call in Bone MarrowTransplantation, Chapman Hall, New York, New York, 1996, Chapter 6.2, pp.162-173.

5. Butt RK, Rowlings, P, Santos G: BMT for chronic myelogenous leukemia (CML). In On Call in Bone MarrowTransplantation. RG Landes, publisher, Chapman Hall, New York, New York, 1996, Chapter 6.4, pp. 188-193.

6. Butt RK, Walsh T: BMT Infection Prophylaxis. In On Call in Bone Marrow Transplantation. RG Landes publisher,Chapman Hall, New York, New York, 1996, Chapter 10.1, pp.438~450.

7. Butt RK, Deeg J: BMT for Aplastic Anemia. In On Call in Bone Marrow Transplantation. RG Landes, Publisher,Chapman Hall, New York, New York 1996, Chapter 6.1, pp.154-162.

8. Butt RK: Bone Marrow Transplantation.In Critical Care 3rd Edition, Editors Sivetta, Taylor, Kirby. Lippincott Raven1996.

9. Butt RK: Immune Ablation and Hematopoietic stem cell support of severe autoimmune disease (SADS). In RecentAdvances in BMT. Editors: Kluwer Academic Publishers, Boston, 1997, pp. 317-333.

10. Butt RK. Immune ablation and hematopoietic stem cell rescue for severe autoimmune diseases (SADS).In CancerTreatment & Research. 77:317-32, 1997.

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Page 6: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

Link CJ Jr. Traynor A. Seregina T. Butt RK. Adoptive immunotherapy for leukemia: donor lymphocytes transduced withthe herpes simplex thymidine kinase I~ene. In Cancer Treatment & Research. :~01:369-75, 1999.

12. Butt RI(: Transplantation for Autoimmune Disease. In Advances in AIIol~eneic Hematopoietic Stem CellTransplantation. Kluwer Academic Publishers. Norwell, Massachusetts: 157-185, 1999.

13. Butt RI(: Suicide Gene Adoptive Immunotherapy. In Advances in AIIol~eneic Hematopoietic Stem CellTransplantation. Kluwer Academic Publisher. Norwell, Massachusetts: 369-376, 1999.

14. Burns WH, and Butt RK: Hematopoietic Stem Cell Transplantation for Multiple Sclerosis. In Multiple SclerosisExperimental and Applied Therapeutics. Editors, Richard Rudick and Donald Goodkins,, 1999.

15. Butt, RK, Rowlings P, Traynor, AE: Hematopoietic Stem Cell Transplantation of Severe Autoimmune Disease: KnowThyself. Editors John Lister and Edward Ball. In Blood and Marrow Transplantation,, 2000.

:~6. Butt RI(, Hematopoietic stem cell transplantation for autoimmune disease. In Modern Therapeutics in RheumaticDiseases Ed Tsokos GC, Section editors: Gay S., Martel Pelletier, J., Moreland, L.W., Pellettier, J-P., Tsokos, G. C.Publisher: Humana Press, Totowa, NJ 2001 Chapter: #29. Pal~es 453-478

17. Butt RI( AIIol~eneic Bone Marrow Transplantation. In Oncolol~y / Hematolol~y Handbook. Ed Steven Rosen andTimothy Kuzel Chapter 19, 442-433, 2001.

:~8. Carrier E, Butt RK. Mobilization and conditioninl~ rel~imens in stem cell transplant for autoimmune diseases. In StemCell Therapy for Autoimmune Disease, Editors Richard Burt and Alberto Marmont, Chapter 2004

19. Snowden J0 Moore J J, Binl~ham S, Pavletic S, Butt, RI(. Hematopoietic stem cell transplantation for rheumatoidarthritis: worldwide experience. In Stem Cell Therapy for Autoimmune Disease, Editors Richard Burt and AlbertoMarmont, 252-260. Chapter 31, pp. 252-260, 2004

20. Guitart J, Butt RK. Hematopoietic stem cell transplantation in patients with autoimmune bullous skin disorders. InStem Cell Therapy for Autoimmune Disease, Editors Richard Burt and Alberto Marmont, Chapter 51, pp 433-436.2004

21. Fassas A, Butt RK. Hematopoietic stem cell transplantation for multiple sclerosis: Findinl~ equipoise. In Stem CellTherapy for Autoimmune Disease, Editors Richard Burt and Alberto Marmont, Chapter 37, pp. 308-319, 2004

22. Butt, RI(, Kenyon, N, Voltarelli JC, Kaufman, D. Hematopoietic stem cell transplantation as treatment for Type IDiabetes. In Stem Cell Therapy for Autoimmune Disease, Editors Richard Burr and Alberto Marmont, Chapter 53, pp.441-446, 2004

23. Oyama Y, Barr, W, Butt RK. Autolol~ous hematopoietic stem cell transplantation for idiopathic inflammatory myositis.In Stem Cell Therapy for Autoimmune Disease, Editors Richard Burt and Alberto Marmont, Chapter 52, pp. 436-441,2004

24. Crail~ R, Butt RI(. Autolosous hematopoietic stem cell transplantation for Crohn’s Disease. In Stem Cell Therapy forAutoimmune Disease, Editors Richard Burt and Alberto Marmont, Chapter 54, pp 447-455, 2004

25. Butt I~K. Hematopoietic Stem Cell Therapy for Patients with Refractory Myasthenia Gravis. In Stem Cell Therapy forAutoimmune Disease,, Editors Richard Burt and Alberto Marmont, Chapter 50, pp. 428-432, 2004

6

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26. Traynor AE, Butt RI(, Marmont AM. Hematopoietic stem cell transplantation for systemic lupus en~hematosus. InStem Cell Therapy for Autoimmune Disease, Editors Richard Burt and Alberto Marmont, Chapter 41, pp. 346-356,2004

27. Slavin S, Marmont AM, Butt RK. AIIogeneic hematopoietic stem cell transplantation for autoimmune diseases. InStem Cell Therapy for Autoimmune Disease, Editors Richard Butt and Alberto Marmont, Chapter 57, pp. 473-478,2004

28. Butt RK, Cohen B, Lobeck L, Bredeson C, Burns W. Treatment of multiple sclerosis by hematopoietic stem celltransplantation. In Multiple Sclerosis Experimental and Applied Therapeutics. Editors, Richard Rudick and DonaldGoodkins, 2002.

29. Butt RI(, Verda L, Immune reconstitution following hematopoietic stem cell transplantation. In Adult and EmbryonicStem Cells. Editors Lanza RP, Blau HM, Melton DA, Moore MAS, Thomas ED, Verfaille CM, Weissman IL, West MD.Academic Press, 2004.

30. Butt RI(, Wulffraat N, Kletzel M, Verda L. Hematopoietic stem cell transplantation for pediatric autoimmune diseases.In Pediatric Hematopoietic Stem Cell Transplantation, Editor R Kline, 2004.

31. Butt R, Statkute L, Oyama Y, Verda L. Stem cell Transplantation for Multiple Sclerosis. In: Multiple SclerosisTherapeutics, 2005, Editors: Rick Rudnick and Jeffrey Cohen

32. Milanetti F, Burt RK. The induction of mixed chimerism using ES cell-derived hematopoietic stem cells. In:Immunolol~ical Barriers to Regernerative Medicine: 2010, Editor: Paul J Fairchild

7

Page 8: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

JOURNALS:

Invited review

1. Butt RK: A Hypothesis of the Role of Antidiuretic Hormone in Preeclampsia. Med H__y.p_. 12:62-66, 1983.

2. Butt RK, and Thorgeirsson SS: Theories of Carcinogenesis. New York Journal of Medicine, 1990.

3. Butt RK, Fojo AT, and Thorgeirsson SS: Multidrug Resistance Due to P-Glycoprotein. Hosp. Pract. April 15, 1990, pp67-77.

4. Butt RK, Bergan R, Chabner BA: HTLV-1-Associated disease. Internal Medicine. April 1991, Vol 12, No. 4, pp 31-40.

S. Link TC0 Butt RK, Bohr VA: Gene Specific Repair of DNA Damage Induced by UV Irradiation and CancerChemotherapeutics. Cancer Cells 3:427-436, 1991.

6. Burr RK, Poirier MC, Link CJ, Bohr VA: Antineoplastic Drug Resistance and DNA Repair. Annals of Oncology 2:325-334,1991.

7. Burt RK, Younl~ N: T-Gam ma-Lym phocytosis. Contemporary Oncolol~y. 2(4):21-28, 1992.

8. Burr RI(, Hess A, Dee~ J: Graft versus Host Disease. Contemporary Oncolol~v, 3(9}:1_9-33, 1993.

9. Burr RI(, Hess A, Burns W: Bone Marrow Transplantation for Multiple Sclerosis. Bone Marrow Transplantation 1995,Vo116, pp 1-6.

10. Burr RK, Burns W, Miller, SD: Bone Marrow Transplantation for Multiple Sclerosis, Returning to Pandora’s box,Immunolo~;y Today 18 (12) 559-562, 1997.

11-. Burr RK: BMT for Severe Autoimmune Diseases: An Idea Whose Time Has Come. Oncolo_~y 1_1_(7): 1001-1017, 1997.

12. Butt RI(, and Traynor AE: Hematopoietic Stem Cell Therapy of Autoimmune Diseases. Current Opinion inHematolol~y, 5, 472-477, 1998.

1-3. Burr RI(, Link C, Traynor AE: Adoptive Immunotherapy After Hematopoietic Stem Cell Transplantation. CurrentOpinion in Oncolol~Y, 10, 525-532, 1998.

14. Butt RI(, Traynor AE: Hematopoietic Stem Cell Transplantation: A New Therapy for Autoimmune Disease. TheeOncolo=kist 4, 77-83, 1999.

15. Butt RI(, Traynor A, Burns W. Hematopoietic stem cell transplantation of multiple sclerosis, rheumatoid arthritis, andsystemic lupus erythematosus. Cancer Treat Res. 1999;101:157-84.

16. Burr RI(, Optimizint~ CD34 Stem Cell Dose in Hematopoietic Transplants. The Oncolol~ist, 4, 265-268, 1999.

1-7. Butt RI(. Clinical utility in maximizing CD34÷ cell count in stem cell grafts. Stem Cells. 17(6):373-6, 1999.

1-8. Burt RK. Traynor AE. Hematopoietic stem cell transplantation: a new therapy for autoimmune disease. Stem Cells.17(6):366-72,1999.

19. Luo K, Butt R. Gene Engineered Erythrocytes for Malaria Prevention, Graft January 2000

8

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20. Link C J, Seregina T, Traynor A, Burr RK. Cellular suicide therapy of malignant disease. The Oncolol~ist, Vol 5 (1), 68-74,2000.

21. Link CI. Seregina T. Traynor A. Bur~ RI(. Cellular suicide therapy of malignant disease. Stem Cells. 18(3):220-6, 2000.

22. Burr, RK, Marmont, A, Schroeder, J, Rosa, R, and Traynor AE, Intense immune suppression for systemic lupus: Therole of hematopoietic stem cells. Journal of Clinical Immunolol~y. 20(:~):31-7, 2000.

23. Burr RI(, Brenner M, Burns, W, Courier E, Firestein G, Hahn B, Link C, McFarland H, Roland M, Territo M, Tsokos G,Traynor A. Gene Marked Autologous Hematopoietic Stem Cell Transplantation of Autoimmune Disease. JournalClinical Immunolol~y, 20(1):1-9, 2000

24. Burr RK, Barr W, Oyama Y, Traynor A, Slavin S. Future strategies in hematopoietic stem cell transplantation forrheumatoid arthritis. J Rheumatol Suppl. 2001 Oct;64:42-8.

25. Carrier E, Traynor A, I$..rt RK. Pros and Cons of Hematopoietic Stem Cell Transplantation for Autoimmune Disease.Current Opinion in Orl~an Transplantation (in press)

26. Su C, Traynor A, Burr, RI(o Update on Stem Cell Transplantation. Resident and Staff Physician 2001 vo147 #2 pp 44-54

27. Burt RI(, Slavin S, Burns WH, Marmont A. Induction of tolerance in autoimmune disease by hematopoietic stem celltransplantation; Getting closer to a cure? Blood. 2002; 99(3): 870-887.

2.8. Blajchman MA. Dzik S. Vamvakas EC. Sweeney J. Snyder EL. Clinical and molecular basis of transfusion-inducedimmunomodulation: summary of the proceedings of a state-of-the-art conference. Stem Cell transplantatic~n forAutoimmune Disease: presented by l}..rt, R. Transfusion Medicine Reviews. :25(2):108-35, 200:~ Apr.

29. Burr, R, Traynor, A, Y Oyama. Y., Barr WG. Plasticity of hematopoietic stem cells: Enough to induce tolerance andrepair tissue? Arthritis and Rheumatism 2002 Apr;46(4):855-8.

30. Oyama Y, Traynor AE, Barr W, Burr RK. AIIogeneic Hematopoietic stem cell transplantation for autoimmune disease.Bone Marrow Transplantation 32, pp $81-83, 2003;

31. Burr RI(, Arnold R, Emmons R, Oyama Y, Marmont A. Stem cell therapy for autoimmune disease: Overview ofconcepts from the Snowbird 2002 tolerance and tissue regeneration meeting. Bone Marrow Transplantation 32, pp.$3-6, 2003

32. Burr RI(, Kozak T. Hematopoietic stem cell transplantation for multiple sclerosis: finding equipoise. Bone MarrowTransplantation 32, pp $45-48, 2003.

33. Burr RK, Marmont A, Arnold R, Heipe F, Firestein GS, Carrier E, Hahn B, Barr W, Oyama Y, Snowden J, Kalunian K,Traynor AE. Development of a phase III trial of hematopoietic stem cell transplantation for systemic lupuserythematosus. Bone Marrow Transplantation 32, $49-52, 2003.

34. Moore J J, Snowden J, Paveltic S, Barr W, Burt R. Hematopoietic stem cell transplantation for severe rheumatoidarthritis. Bone Marrow Transplantation, 32, pp. $53-56, 2003.

35. Burr RK, Verda L, Statkute L, O.uigley K, Yaung K, Brush M, Oyama Y. Stem cell therapy for autoimmune disease.Clinical Advances in Hematoloho3’ and OncoIoh~, 2004 (in press).

36. Burt RK, Verda L, Slavin S. Non-myel;oablative stem cell transplantation (NST) for autoimmune diseases.Seminars in Immunol3atholol~v. 2004 (in press)~

9

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37. Butt RI(, Verda L, Cohen B. Hematopoietic stem cell transplantation for multiple sclerosis. Archives of Neurology,2004 (in press).

38. Burr RI(, Verda L, Statkute, Oyama Y. Unique clinical aspects of hematopoietic stem cell transplantation forautoimmune diseases. Curr Opin Orl~an Transplant 2004, 9:49-53

39. Butt RI(, Kallunian K, Patel D, Thomas J, Yeal~er A, Traynor A, Heipe F, Arnold R, Marmont A, Collier D, Glatstein E,Snowden J. The rationale behind autologous autoimmune hematopoietic stem cell transplant conditioning regimens:concerns over the use of total-body irradiation in systemic sclerosis. Bone Marrow Transplant. 2004 Nov;34(9):745-51.

40. Burr I~1(, Cohen B, Rose J, Petersen F, Oyama Y, Stefoski D, Katsamakis G, Carrier E, Kozak T, Muraro PA, Martin R,Hintzen R, 51avin S, Karussis D, Hagl~ial~ S, Voltarelli JC, Ellison (3W, Jovanovic B, Popat U, McGuirk J, Statkute L, VerdaL, Haas J, Arnold R. Hematopoietic stem cell transplantation for multiple sclerosis. Arch Neurol. 2005 Jun;62(6):860-4.

41. Burr RI(, Furst DE, Weisman MH, Sullivan KE. Ruminating on rheumatoid arthritis and transplantation. Clin Immunolo2005 May;:115(2):129-30.

42. Burr RI(, Marmont A, Oyama Y, Slavin S, Arnold R, Hiepe F, Fassas A, Snowden J, Schuening F, Myint H, Patel DD,Collier D, Heslop H, Krance R, Statkute L, Verda L, Traynor A, Kozak T, Hintzen RC~ Rose JW, Voltarelli J, Loh Y, TerritoM0 Cohen BA, Craig RM, Varga J, Barr WG. Randomized controlled trials of autologous hematopoietic stem celltransplantation for autoimmune diseases: the evolution from myeloablative to lymphoablative transplant regimens.Arthritis Rheum. 2006 Dec;54(12):3750-60.

43. Marmont AM, Burr RI(. Hematopoietic stem cell transplantation for systemic lupus erythematosus, theantiphospholipid syndrome and bullous skin diseases. Autoimmunity. 2008 Dec;41(8):639-47.

44. Burr RK, Testori A, Craig R, Cohen B, Suffit R, Barr W. Hematopoietic stem cell transplantation for autoimmunediseases: what have we learned? J Autoimmun. 2008 May;30(3):116-20. Epub 2008 Feb 1.

45. Burr RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, Wen Y, Rapp JA, Kessler J.Clinical applications of blood-derivedand marrow-derived stem cells for nonmalignant diseases. JAMA. 2008 Feb 27;299(8):925-36

46. Voltarelli JC, Couri CE, Stracieri AB, Oliveira MC, Moraes DA, Pieroni F, Barros GM, Madeira MI, Malmegrim KC, Foss-Freitas MC, Sim6es BP, Foss MC, Squiers E, Butt RI(. Autologous hematopoietic stem cell transplantation for typediabetes. Ann N Y Acad Sci. 2008 Dec;1150:220-9.

47. Milanetti F, Abinun M, Voltarelli JC, Butt RK. Autolol~ous hematopoietic stem cell transplantation for childhoodautoimmune disease. Pediatr Clin North Am. 2010 Feb;57(1):239-71

48. Burt RK, Abinun M, Farge-Bancel D, Fassas A, Hiepe F, Havrdov~ E, Ikehara S, Loh Y, Marmont du Haut Champ A,Voltarelli JC, Snowden J, Slavin S. Risks of immune system treatments Science. 2010 May 14;328(5980):825-6

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Articles

1. Butt RK, and Thorgeirsson 55: Coinduction of MDR-1 Multi-Drug-Resistance (MDR-1) and cytochrome P-450 genes inrat liver xenobiotics. J. Natl. Cancer Inst. 80: 1383-1386, 1988.

2. Burr RK, Garfield SH,. Johnson, K, and Thorgeirsson SS: Transformation of rat liver epithelial ceils with v-H raf or v-rafcauses expression of MDR-1, glutathione-S transferase P and increased resistance to cytotoxic chemicals:Carcinol~enesis 9: 2329-2332, 1988.

Burr RK, Gupta-Burt S, Suki, WN, Barcenas CG, Ferguson J J, and Van Buren CT: Reversal of left ventricular dysfunctionafter renal transplantation. Annals of Internal Medicine 111:635-640, 1989.

4. Burr RK, Parnis S, Nakatani T, Gart JJ, Diek JA, and Fergusson J J: The effect of partial pressure of carbon dioxide oncanine coronary sinus blood flow and myocardial infarct size. Journal of Applied Cardiolol~y. Vol 6 Number 7, 1991,pp 31-41.

5. Gant TW, Silverman JA, Bisgaard HC, Burr, RK, Marino PM, Thorgeirsson. 55: Induction of multi-drug resistance(MDR) and cytochrome P4501A gene families in primary cultured hepatocytes by xenobiotics. Evidence for receptormediated mechanisms of regulation. Molecular Carcinol~enesis 4:400-509, 1991.

6. Nakatsukasa H, Evarts RP, Burr RK, Nagy P, and Thorgeirsson SS: Cellular pattern of MRD gene expression duringchemical hepato-carcinogenesis in the rat. Molecular Carcinogenesis, 6:190-198, 1992

7. Burr RK, Shar~man, WH, Karp BI, Wilson W: Mental neuropathy: Harbinger of tumor progression or relapse. Cance_Gr70:877-881, 1992.

8. Burr RK, Ruvollo P, Hess A, Burns W: Syngeneic bone marrow transplantation in Lewis rats with experimentalautoimmune encephalitis. Journal of Neuroscience Research 1995, vol 41:526-531.

9. Fisher A. Ruvollo P, Burr R, Hess A: Characterization of autorective T cell repertoire in cyclosporine induced syngeneicgraft versus host disease: A highly conserved repertoire mediates autoregression. Journal of Immunology. 1995, vol154, #8, pp 3713-3725.

10. Mueller BU. Burr R. Gulick L. Jacobsen F. Pizzo PA. Horne M. Disseminated intravascular coagulation associated withgranulocyte colony-stimulating factor therapy in a child with human immunodeficiency virus infection. Journal ofPediatrics. 126(5 Pt 1): 749-52, 1995 May.

11. Burr RK, Traynor A, Ramsey-Goldman R: Hematopoietic stem cell transplantation for systemic lupus erythematosus.New Enl~land Journal of Medicine 337(24): 1777-1778, 1997.

12. Link CJ, Burr RK, Traynor AE, Drobyski, WR: Adoptive immunotherapy for leukemia: Donor lymphocytes transducedwith the herpes simplex thymidine kinase gene for remission induction. Human Gene Therapy 9:115-134, 1998.

13. Burr RK, Padilla, J, Begolka, WS, DalCanto MC, Miler SD: Effect of disease stage on outcome after syngeneic bonemarrowtransplantation for relapsing experimental autoimmune encephalomyelitis. Blood, 97, (7); 2609-2616 1998.

14. Burr RK, Traynor AE, Cohen B, et. al.: T-cell depleted autologous hematopoietic stem cell transplantation for multiplesclerosis: Report on the first three patients. Bone Marrow Transplantation. 21, 539-541, 1998.

15. Butt, RK, Traynor, AE, Pope R, Schroeder J, Cohen B, Karlin KH, Lobeck L, Goolsby C, Rowlings, P, Davis FA, Stefoski D,Terry C, Keever-Traynor, C, Rosen S, Vesole, D, Fishman M, Brush M, Mujias S, Villa, M, Burns WH: Treatment of

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autoimmune diseases by intense immunosuppressive conditionin8 and autolo8ous hematopoietic stem celltransplantation. Blood 92 (10), 3505-3514, 1998.

16. Burt RK, Drobyski WR, Traynor AE, Link CI: Herpes simplex thymidine kinase (HStk) transduced donor lymphocytes.Bone Marrow Transplantation 24, 1043-1051, 1999.

17. Butt, I~K, Kuzel TM, Fishman M, Brush M, Villa M, Welles C, Rosen S0 and Traynor AE: Stem cell component therapy:Supplementation of unmanipulated marrow with CD34 enriched peripheral blood stem cells. Bone MarrowTransplantation, 23, 381-386, 1999.

18. Butt RI(, Constantinos G, Schroeder J, Traynor A. Steffwn J, Schuenin8, F, Graziano, F, Mineishi S, Brush M, Fishman,M, Welles, Rosen C, S, Pope, R: Autolol~ous hematopoietic stem cell transplantation of refractory rheumatoidarthritis: Sustained remission in two of four patients. Arthritis and Rheumatism, 42(11), 2281-2285. 1999.

:~9. Butt, RK, Padilla, J, Dal Canto MC, Miller, SD: Viral hyperinfection of the central nervous system and hish mortalityfollowin8 hematopoietic stem cell transplantation for treatment of Theiler’s murine encephaleomyelitis virus (TMEV)- induced demyelineatinl~ disease. BIo~od, 94(8), 2915-2922 1999.

20. Traynor AE, and Butt RK: Hematopoietic stem cell transplantation for active SLE. Rheumatolo~y, 38, 767-772, 1999.

21. Keller GN, Berzofsky RN, Butt I~, Stefka J, Traynor A, Link C, LeFever, A. The determination of endotoxin in the finishedcellular product. Cytotherapy 1(5), 423-428, 1999.

22. Butt RI(, Guitart, Traynor AE, Link C, Rosen S, Kuzel TM: AIIol~eneic hematopoietic stem cell transplantation foradvanced mycosis funsoides, Evidence of a I~raft versus tumor effect. Bone Marrow Transplantation, 25, 111-113,2000.

23. Traynor A, Schroeder J, Rosa R, Chenl~ D., Stefka J, Majais S, Baker S, Butt RK: Treatment of severe lupuserythematosus with hil~h-dose intense chemotherapy and hematopoietic stem cell transplantation: a phase I study.The Lancet, Vo1356, 701-707, 2000.

24. Butt RI(, Fassas A, Snowden J et.al. Collection of hematopoietic stem cells from patients with autoimmune diseases.Bone Marrow Transplantation 28(1):1-12, 2001 July.

25. Dee8 HJ. Blazar BR. Bolwell BJ. Long GD. Schuenin~ F. Cunninsham J. Rifkin RM. Abhyankar S. Bri88s AD. Butt fl. LipaniJ. Roskos LK. White JM. Havrilla N. Schwab G. Heslop HE. Treatment of steroid-refractory acute 8raft-versus-hostdisease with anti-CD147 monoclonal antibody ABX-CBL. Blood. 98(7):2052-8, 2001 October 1.

26. Butt RK. Barr W. Oyama Y. Traynor A. Slavin S. Future stratel~ies in hematopoietic stem cell transplantation forrheumatoid arthritis. Journal of Rheumatoloh-=,y - Supplement. 64:42-8, 2001 October.

27. Pavletic SZ. Klassen LW. Pope R. O’Dell JR. Traynor AE. Haire CE. Graziano F. Oyama Y. Barr W. Butt RK. Treatment ofrelapse after autolosous blood stem cell transplantation for severe rheumatoid arthritis. Journal of Rheumatolo~ySupplement. 64:28-31, 2001 October.

28. Mehta J. Oyama Y. Winter J. Williams S. Tallman M. Sinl~hal S. Villa M. Shook T. B..tt R. Traynor A. Soft G. Masarik S.Ramsey G. Gordon L. CD34(+) cell collection efficiency does not correlate with the pre-leukapheresis hematocrit.Bone Marrow Transplantation. 28(6):597-601, 2001 September.

29. B.,tt RE. Gene therapy to re-establish self-tolerance. Blood. 97(4):8833, 2001 February 15.

30. Oyama, Y, Papadopoulos, EB, Miranda M, Traynor, A and Butt, RK. AIIol~eneic stem cell transplantation for EvansSyndrome. Bone Marrow Transplantation, 2001; 28: 903-905.

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3:1. Oyama Y, Cohen B, Brush M, Rodriquez J, Brush M, Traynor A, Butt RK. Engraftment syndrome: A common cause forrash and fever following autologopus hematopoietic stem cell transplantation for multiple sclerosis. Bone MarrowTransplantation 2002 29 (1) 8:1-5.

32. Traynor A, Butt R. Relapse of Systemic Lupus erythematosus. The Lancet, 357; 807-808, March 10, 200:1.

33. Guitart J, Wickless, SC, Oyama Y, Kuzel, TM, Rosen ST, Traynor A, Butt R. Long term Remission after allogeneichematopoietic stem cell transplantation for refractory cutaneous T cell lymphoma. Archives of Dermatolol~y.138{:10):1359-65, 2002 Oct.

34. Traynor A, Barr W, Rosa, RM, Rodriquez J, Oyama, Y, Baker S, Brush M, Burr RI(. Hematopoietic stem celltransplantation for severe and refractory lupus, analysis after 5 years. Arthritis and Rheumatism 6(1:1):2917-23, 2002Nov.

35. Butt RK, Traynor AE, Oyama Y, Craig R. High dose immune suppression and autologous hematopoietic stem celltransplantation in refractory Crohn’s Disease" Blood 2003 Mar 1;10:1(5):2064-6.

36. Butt RI(; Drobyski, W; Traynor AE, Seregina, T, Stefka, J, Burns WH and Link CJ. Relapsed Leukemia After AIIogeneicStem Cell Transplantation: Remission Induction of malignancies with interleukin-2 activated and herpes simplexthymidine kinase I~ene transduced lymphocytes. Experimental Hematolol~y 3:1(10): 903-:10, 2003.

37. B.,tt RK, Oyama Y, Traynor AE, Quigley K, Brush M, Rodriquez J, Barr W. Hematopoietic stem cell transplantation forsystemic sclerosis with rapid improvement in skin scores: Is neo-angiogenesis occurrinl~? Bone MarrowTransplantation, 32, $65-67, 2003.

38. Butt RK, Pearce W, Luo K, Oyama Y, Gheoghiade M. Hematopoietic stem cell transplantation for cardiac andperipheral vascular disease. Bone Marrow Transplantation 32, $29-31,2003.

39. Link CJ, Seregina T, Edleman M, Young W-B, Butt RI(, Kisselev S. Transduction of hematopoietic stem cells with aretroviral vector expressinl~ the neomycin phosphotransferase gene. Bone Marrow Transplantation, 32, $32-35, 2003.

40. Butt RI(, Cohen BA, Russell E, Spero K, Joshi, A Oyama, Y, Karpus WJ, Luo K, Jovanovic, J, Traynor AE, Burns, WH.Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of intense immune suppression toprevent disease prol~ression in patients with high disability scores Blooda :102 (7):2373-8, 2003.

4:1. Butt RI(, Oyama Y, Verda L, Quigley K, Brush M, Yaung K, Statkute L, Traynor A, Barr W. Remission of severe andrefractory arthritis by allogeneic mixed chimerism. Arthritis and rheumatism, 2004, Vol 50 #8, 2466-2470.

42. Butt RI(, verda L, Kim D-A, Oyama Y, Link CJ. Embryonic stem cells as an alternate marrow donor source: engraftmentwithout graft versus host disease. Journal of Experimental Medicine, 2004, Apr 5;199(7):895-904.

43. Oyama Y, Parker ER, Brieva J, Statkute L, Verda L, Butt RK. High dose immune suppression and autologoushematopoietic stem cell transplantation in refractory pemphigus foliaceus. Archives of Dermatolol~y, 2004 (inreview).

Zl4.Snowden JA, Passwel~ J, Moore JJ, Milliken S, Cannell P, Van Laar J, Verburg R, Szer J, Taylor K, Joske D, Rule S,Bin~ham SJ, Emery P, Butt RI(, Lowenthal RM, Durez P, McKendry R J, Pavletic SZ, Espil~ado I, Jantunen E, Kashyap A,Rabusin M, Brooks P, Bredeson C, Tyndall A. Autologous hemopoietic stem cell transplantation in severe rheumatoidarthritis: a report from the EBMT and ABMTR. J Rheumatol. 2004 Mar;3:~(3):482-8.

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45. Oyama Y, Craig RM, Traynor AE, Quigley K, Statkute L, Halverson A, Brush M, Verda L, Kowalska B, Krosnjar N, KletzelM, Whitington PF, Burr RK. Autologous hematopoietic stem cell transplantation in patients with refractory Crohn’sdisease. Gastroenterolol~y. 2005 Mar;128(3):552-63.

46. Muraro PA, Douek DC, Packer A, Chung K, Guenaga F J, Cassiani-lngoni R, Campbell C, Memon S, Nagle JW, Hakim FT,Gress RE, McFarland HF, Butt RK, Martin R. Thymic output generates a new and diverse TCR repertoire afterautologous stem cell transplantation in multiple sclerosis patients= J E__~p_Med. 2005 Mar 7;201(5):805-16. Epub 2005Feb 28.

47. Traynor AE, Corbridge TC, Eagan AE, Barr WG, Liu O~ Oyama Y, Burr RK. Prevalence and reversibility of pulmonarydysfunction in refractory systemic lupus: improvement correlates with disease remission followinl~ hematopoieticstem cell transplantation. Chest. 2005 May;127(5):1680-9.

48. Statkute L, Traynor A, Oyama Y, Yaung K, Verda L, Krosnjar N, Burr RI(. Antiphospholipid syndrome in patients with

systemic lupus erythematosus treated by autologous hematopoietic stem cell transplantation. Blood. 2005 Oct

15;106(8):2700-9.

49. Burr RK, Traynor A, Statkute L, Barr WG, Schroeder J, Verda L, Krosnjar N, Quigley K, Yaung K, Villa M, Takahashi M,Jivanovic B, Oyama Y. Nonmyeloablative hematopoietic stem cell transplantation for systemic lupus erythematosus.JAMA 2006, February 1st, Vol 295, No 5, 527-535.

50. Verda L, Luo K, Kim DA, Bronesky D, Kohm AP, Miller SD, Statkute L, Oyama Y, B..rt RK. Effect of hematopoieticgrowth factors on severity of experimental autoimmune encephalomyelitis. Bone Marrow Transplant. 2006Sep;38(6):453-60.

51. Loh Y, Oyama Y, Statkute L, Quigley K, Yaung K, Gonda E, Barr W, Jovanovic B, Craig R, Stefoski D, Cohen B, Burr RK.Development of a secondary autoimmune disorder after hematopoietic stem cell transplantation for autoimmunediseases: role of conditioning regimen used. Blood. 2007 Mar 15;109(6):2643-548.

52. Statkute L, Verda L, Oyama Y, Trm/nor A, Villa M, Shook T, Clifton R, Jovanovic B, Satkus J, Loh Y, O, uigley K, Yaung K,Gonda E, Krosnjar N, Spahovic D, B~rt RK. Mobilization, harvesting and selection of peripheral blood stem cells inpatients with autoimmune diseases undergoing autologous hematopoietic stem cell transplantation. Bone MarrowTransplant. 2007 Mar;39(6):317-29.

53. Loh Y, Oyama Y, Statkute L, Verda L, Quigley K, Yaung K, Barr W, Jovanovic B, Burr RK. Non-myeloablative allogeneichematopoietic stem cell transplantation for severe systemic sclerosis: graft-versus-autoimmunity without graft-versus-host disease? Bone Marrow Transplant. 2007 Apr;39(7):435-7.

54. Voltarelli JC, Couri CE, Stracieri AB, Oliveira MC, Moraes DA, Pieroni F, Coutinho M, Malmegrim KC, Foss-Freitas MC,Simoes BP, Foss MC, Squiers E, Bur~ RK. Autologous nonmyeloablative hematopoietic stem cell transplantation innewly diagnosed type I diabetes mellitus. JAMA. 2007 Apr 11;297(14):1568-76.

55. Loh Y, Oyama Y, Statkute L, Traynor A, Satkus J, Quigley K, Yaung K, Barr W, Bucha J, Gheorghiade M, BurrAutologous hematopoietic stem cell transplantation in systemic lupus erythematosus patients with cardiacdysfunction: feasibility and reversibility of ventricular and valvular dysfunction with transplant-induced remission.Bone Marrow Transplant. 2007 Jul;40(1):47-53.

56. Oyama Y, Barr WG, Statkute L, Corbridge T, Gonda EA, Jovanovic B, Testori A, Burr RK. Autolol~ous non-myeloablativehematopoietic stem cell transplantation in patients with systemic sclerosis. Bone Marrow Transplant. 2007 Jul 23;[£pub ahead of print]

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57. Oyama Y, Sufit R, Loh Y, Statkute L, Yaung K, Quigley K, Gonda E, Sphavoic D, Bronesky D, Burr RK. Autologous non-myeloablative hematopoietic stem cell transplantation for refractory CIDP. Neurolol~y, 2007 Oct 30;69(18):1802-3.

58. Statkute L, Oyama Y, barr WG, Suflt R, ho S, Verda L, Loh Y, Yaung K, Quigley K, Butt RK. Autologous non-myeloablative hematopoietic stem cell transplantation for refractory systemic vasculitis. Annals of the RheumaticDiseases. 2008 Jul;67(7):991-7

59. Verda L, An Kim D, Ikehara S, Statkute L, Bronesky D, Petrenko Y, Oyama Y, He X, Link C, Vahanian NN, BurrHematopoietic Mixed Chimerism Derived From AIIogeneic Embryonic Stem Cells Prevents Autoimmune DiabetesMellitus In Nod Mice.. Stem Ce~ls. 2008 Feb;26(2):38:~-6

Mandelbrot DA, Santos PW, Butt RK, Oyama Y, Block GA, Ahya SN, Rosa RM, Traynor AE.Resolution of SLE-relatedsoft-tissue calcification following haematopoietic stem cell transplantation. Nephrol Dial Transplant. 2008Aug;23(8):2679-84

61. Wen Y, Ouyang J, Yang R, Chen J, Liu Y, Zhou X, Burr RI(. Reversal of new-onset type 1 diabetes in mice by syngeneicbone marrow transplantation.. Biochem Biophys Res Commun. 2008 Sep 19;374(2):282-7.

62. Levitsky J, Miller J, Leventhal J, Huang X, Flaa C, Wang E, Tambur A, Burr RI(, Gallon L, Mathew JM. The human "TregMLR": immune monitoring for FOXP3+ T regulatory cell generation. Transplantation. 2009 Dec 15;88(11):1303-11.

63. Oyama Y, Burr RI(, Thirkill C, Hanna E, Merrill K, Keltner J A case of autoimmune-related retinopathy and opticneuropathy syndrome treated by autologous nonmyeloablative hematopoietic stem cell transplantation. JNeuroophthalmol. 2009 Mar;29(1):43-9.

64. Couri CE, Oliveira MC, Stracieri AB, Moraes DA, Pieroni F, Barros GM, Madeira MI, Malmegrim KC, Foss-Freitas MC,Sim6es BP, Martinez EZ, Foss MC, Burr RI(, Voltarelli JC C-peptide levels and insulin independence followingautologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type I diabetes mellitus.JAMA. 2009 Apr 15;301(15):1573-9.

65. Butt RI(, Loh Y, Cohen B, Stefoski D, Balabanov R, Katsamakis G, Oyama Y, Russell EJ, Stern J, Muraro P, Rose J, TestoriA, Bucha J, Jovanovic B, Milanetti F, Storek J, Voltarelli JC, Burns WH. Autologous non-myeloablative haemopoieticstem cell transplantation in relapsing-remitting multiple sclerosis: a phase 1/11 study. Lancet Neurol. 2009Mar;8(3):244-53.

66. Zhang L, Bertucci AM, Ramsey-Goldman R, Butt RK, Datta SK Regulatory T cell (Treg) subsets return in patients withrefractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated withimmunological remission of lupus. J Immunol. 2009 Nov 15;183(10):6346-58

67. Butt RK, Testori A, Oyama Y, Rodriguez HE, Yaung K, Villa M, Bucha JM, Milanetti F, Sheehan J, Rajamannan N, PearceWH. Autologous peripheral blood CD133÷ cell implantation for limb salvage in patients with critical limb ischemia.Bone Marrow Transplant. 2010 Jan;45(1):111-6.

68. Hamerschlak N0 Rodrigues M, Moraes DA, Oliveira MC, Stracieri AB, Pieroni F, Barros GM, Madeira MI, Sim6es BP,Barreira AA, Bruin DG, Ribeiro AA, Kutner JM, Tylberi CP, Porto PP, Santana CL, Neto JZ, Barros JC, Paes AT, Butt RI(,Oliveira EA, Mastropietro AP, Santos AC, Voltarelli JC. Brazilian experience with two conditioning regimens in patientswith multiple sclerosis: BEAM/horse ATG and CY/rabbit ATG. Bone Marrow Transplant. 2010 Feb;45(2):239-48.

69. Dubinsky AN, Butt RK, Martin R, Muraro PA.. T-cell clones persisting in the circulation after autologous hematopoieticSCT are undetectable in the peripheral CD34+ selected graft. Bone MarrowTransplant. 2010 Feb;45(2):325-31.

70. Burt RI(, Craig RM, Milanetti F, O, uigley K, Gozdziak P, Bucha J, Testori A, Halverson A, Verda L, de Villiers WJ,Jovanovic B, Oyama Y. Autologous nonmyeloablative hematopoietic stem cell transplantation in patients with severe

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anti-TNF refractory Crohn disease: long-term follow-up. Blood. 2010 Dec 23;116(26):6123-32. Milanetti F, Abinun M,Voltarelli JC, Burt RK.

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ABSTRACTS (selected abstracts, not complete publication history):

1. Burr RK, R Hess, Burns A, Ruvollo W, Fischer P, Schiao A, Guimaraes C, Barrett A: Syngeneic bone marrowtransplantation eliminates autoreactive VI38.2 T-lymphocytes form the spinal cord of Lewis rats with experimentalallergic Encephalomyelitis. (abstact) Bone Marrow Transplantation, 1994.

2. Butt RK, Burns W, Schiao C, Hansmann K, McKeown, L, Barrett J.: Plasma von Willebrand factor in patientsundergoing allogeneic bone marrow transplantation. (abstract) Bone MarrowTransplantation, 1994.

3. Couriel D, Cottler-Fox M, Burr RK, Dunbar C, Hensen N, Young, NS, Barrett, AJ: T-cell marrow depleted marrowtransplants with delayed lymphocyte add-back to prevent relapse in ~atients with leukemia and MDS, (abstract)1321, 81ood, 1994.

4. Burr RK, Padilla J Meyer M, Miller S.: Induction of T cell unresponsiveness to myelin after syngeneic marrowtransplant in SJL/J mice with relapsing experimental allergic encephalomyelitis (EAE). Keystone symposium, 1996.

5. Butt RK, et. al. T-Cell depleted autologous hematopoietic stem cell transplantation for multiple sclerosis. Blood 90,383, 1997.

6. Traynor AE, Burr RK: Hematopoietic stem cell transplantation for systemic lupus erythematosus. Lupus, 1998.

Burr RK, Traynor AE, B Cohen, KH Karlin, Davis FA, Stefoski D, Terry C, Lobeck L, Keever-Taylor, WH Burns:Autologous lymphocyte depleted hematopoietic stem cell transplantation for rapidly progressive multiple sclerosis;minimal toxicity from a cyclophosphamide/total body irradiation/methylprednisolone conditioning regimen. Journalof Neurological Sciences, Abstracts of the XVI World Congress of Neurology, September 14-19, 1997, Buenos Aires,Argentina.

B. RK Burr, Villa M, Fishman A, Brush M, Rosen S, Traynor AE: Stem cell component therapy; supplementation ofunmanipulated marrow with CD34 enriched peripheral blood stem cells. Blood (abstract. 564), 92 (10) suppl.1, 140a,1998.

9. Kuzel T, Traynor AE, Guitar J, Rosen S, Link C, Villa M, Fishman, M, Brush M, Butt RK. AIIogeneic hematopoieticstem cell transplantation for advanced mycosis fungoides: evidence of a graft-versus-tumor effect. Blood 92 (10),suppl. 1, 286a, 1998.

10. Butt RK, Burns WH., Cohen B, Karlin KH, Lobeck L0 Schroeder J, Pope R0 Scheuning F, Graziano, F, Rosa R, Keever-Taylor C, Rosen S, Traynor AE. T-cell depleted autologous hematopoietic stem cell transplantation in patients withsevere autoimmune diseases. Blood (abst. 1327) 92 (10), suppl.1, 324a, 1998.

11. Traynor AE, Cheng, D~ Heltemes I_, Stefka J, Butt R, Link C: Anti-idiotypic lymphocytes from the peripheral blood of asmoldering myeloma patient can be cultured and successfully expanded ex-vivo by use of idiotype transduceddendritic cells. Blood (abstract. 4223), 92 (10) suppl. 1, 283b, 1998.

12. Link CJ, Drobyski WR, Traynor AE, Taylor C, Serengina T, Stefka J, Horowitz M, Levy JP, Burns WH, Rosen S, Butt RK:Adoptive immunotherapy for leukemia: donor lymphocytes transduced with the herpes simplex thymidine kinase(HSTK) gene persist despite chemotherapy. Blood {abst 4655), 92 (10), suppl. 1, 3856, 1998.

13. Stefka J, Traynor AE, Furtado M, Rosen S, Link C, Sereglina T, Levy J, Taylor C, Burns W, Drobyski B, Butt RI(:Characteristics of donor lymphocytes transduced ex vivo with a retroviral vector containing the herpes simplexthymidine kinase (HSKK) gene after selection and expansion. Blood (abstract. 4661), 912 (10), Suppl 1, 3866, 1998.

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14. Butt RK, Pope RM, Schroeder JL, Rosa RM, Rosen S, Traynor AE: Hematopoietic stem cell transplantation ofautoimmune disease. Arthritis and Rheumatism. Abstract. 1253), 41 (9), Suppl., 5241, 1998.

15. Kolar D J, Emanuel D J, Smith FO, Azzarelli B, Butt R: Bone marrow transplantation (BMT) in multiple sclerosis (MS),Journal of Neurolol~ical Sciences (abstract 1-31-21), 150 (Suppl.) 550, 1997.

16. Butt RI(, Padilla J, DalCanto MC, Miller SD: Reversal of neurolo{~ic deficits after bone marrow transplantation inrelapsing experimental autoimmune encephalomyelitis: Effect of disease duration. Journal of Neurolol~ical Science(abstract 1-31-09), 150 (Suppl.), 548, 1997.

17. Butt I~K, Georganas C, Schroeder J, Traynor A, Stefka J, Schuening F, Graziano F, Mineishi S, Cheng D, Rosen S, Pope,R: Autologous hematopoietic stem cell transplantation of refractory rheumatoid arthritis. Arthritis & Rheumatism(abstract 33), Vol. 42 No. 9 (Suppl.) $76, September 1999.

18. Stefka J, Traynor A, Schroeder J, Rosa R, Tsen{~ T, Cheng D, Butt, RK: Resolution of restricted T cell receptor ~ chainrepertoire in lymphocytes of patients with active Systemic lupus erythematosus after hematopoietic stem celltransplantation. Arthritis & Rheumatism (abstract 205), Vol. 42 No. 9 (Suppl.) $105, September, 1999.

19. Traynor A, Schroeder J, Rosa RM, Mujais S, Rosen S, Bowyer S, Jung L, Butt R: Stem cell transplantation for resistantlupus. Arthritis & Rheumatism (abstract 595), Volume 42 No. 9 (suppl.), $170, September, 1999.

20. Traynor AE, Cheng D, Stefka J, Tseng T, Butt RI(: immune reconstitution after stem cell transplant for lupus ischaracterized by lasting normalization of T-cell subsets. Arthritis & Rheumatism (abstract 1160), volume 42 No. 9(Suppl.) $264, September, 1999.

21. Kni{~ht SJ, Traynor A, Fishman M, Brush M, Welles C, Butt, RK: Pain, anxiety, and affect in related donors undergoingbone marrow (BM) versus peripheral blood stem cell mobilization (PBSC). Blood (abstract 711), Volume 94, No 10,(Supplement I) Part 1 of 2), 162a, November 15, 1999.

22. Cheng D, Kini AR, Rodril~uez J, Butt RI(, Peterson LC, Traynor AE: Microvascular density and cytotoxic T cell activationcorrelate with response to thalidomide therapy in myeloma patients. Blood (abstract 1408), Volume 94, No. 10,(Supplement I) Part 1 of 2), 315a, November 15, 1999.

23. Butt RK, Burns W, Scheuning F, Schroeder J, Pope R, Cohen B< Karlin K, Lobeck L, Brush M, Fishman M, Welles C, VillaM, Shook T, Traynor A. Mobilization of peripheral blood stem cells in patients with autoimmune disease: (abstract1475), Volume 94, No. 10, (Supplement I) Part 1 of 2, 330a, November 15, 1999.

24. Traynor AE, Cheng D, Stefka J, Rosa RM, Schroeder J, Butt RK: Stem cell transplantation for severe systemic lupus isassociated with sustained remission from disease and normalized TH1/TH2 activity. Blood (abstract 1577), Volume94, No. 10, (Supplement I) Part 1 of 2, 354a, November 15, 1999.

25. Butt RI(, Stefka J, Cheng D, Schroeder J, Rosa R, Traynor A: Resolution of restricted T cell receptor ~ chain repertoirein lymphocytes of patients with active systemic lupus erythematosus after hematopoietic stem cell transplantation.Blood (abstract 1578), Volume 94, No. 10, (Supplement I) Part 1 of 2, 354a, November 15, 1999.

26. Butt RI(, Burns W, Cohen B, Karlin K, Lobeck L, Brush M, Fishman M, Welles C, Traynor A: Results of a recentlycompleted phase I study of autolo~ous hematopoietic stem cell transplantation (HSTK) for multiple sclerosis (MS).Blood (abstract 1579), Volume 94, No. 10, (Supplement I) Part I of 2, 354a, November 15, 1999.

27. Link C.I, Drobyski WR, Traynor AE, Sere{~ina T, Taylor CA, Burns WH, Rosen ST, Butt, RI(: Adoptive immunotherapy forleukemia: Donor lymphocytes transduced with the herpes simplex thymidine kinase (HSTK) gene. Blood (abstract1631, Volume 94, No. 10, (Supplement i) Part I of 2, 330a, November 15, 1999.

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Page 19: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

28. Link CJ, Moorman DW, Edelman M, Hoop E, Butt, RK, Seregina T: Eosinophilia after intraperitoneal transplantation ofxenogeneic murine vector producer cells. Blood~ (abstract #3338), Volume 94, No. 10 (Supplement I) Part 2 of 2, 43b,November :~5, 1999.

29. Burt RK, Traynor A, Drobyski W, Burns W, Stefka J, Cheng D, Keever-Taylor C, Seregina C, Link C: Selecting a cell dosefor transgenic donor lymphocyte infusion: Effect of selection and ex vivo culture on T lymphocytes. Blood, (abstract4643, volume 94, No. 10 (Supplement I) Part 2 of 2, 317b, November 15, :2999.

30. Butt RK, Traynor A, Stefka J, Cheng D, Kuzel T, Seregina T, Link C: Transgeneic herpes simplex thymidine kinase(HSTK) allogeneic Imphocyte infusion induces antilymphoma response and chronic graft versus host disease (GVHD)that responds to ganciclovir. Blood, (abstract 4907), Volume 94, No. 10 (Supplement I) Part 2 of 2, 376b, November15, 1999.

31. Butt RK, Padilla J, Dal Canto MC, Miller SD: High mortality after hematopoietic stem cell encephalomyelitis Virus(TMEV) induced demyelinating disease. Blood~ (abstract 4644) volume 94, No. 10 (Supplement I) Part 2 of 2, 317b,November 15, 1999.

32. Butt RK, Fishman M, Brush M, Fishman M, Welles C, Villa M, Kawauchi, Schilder L, Shook T, Traynor A: High doseallogeneic stem cell infusion by augmentation of unmanipulated marrow with CD34 enriched peripheral blooddecreases day 100 mortality without increasing chronic GVHD. Blood, (abstract 4933, Volume 94, No. 10(Supplement I) Part 2 of 2, 38:~b, November 15, 1999.

33. Miranda M, Reich L, Traynor A, Young E, Papadopoulas M, Fishman M, Welles C, Butt RK: Cure of Evans syndrome(autoimmune hemolytic anemia and idiopathic thrombocytopenia purpura) by allogeneic hematopoietic stem celltransplantation. Blood, (abstract 4948), Volume 94, No. 10 (Supplement I) Part 2 of 2, 384b, November 15, 1999.

34. Moorman DW, Seregina T, Edleman, M, Christensen E, Tennant L, Butt RK, Link CI. Intraperitoneal immune responseto murine vector producer cells (VPC) in women with ovarian cancer. Molecular Therapy Vol 1, No 5, $53, 2000.

35. Butt R0 Link CJ, Traynor A, Cheng D, Kuzel T, Luo K, seregina T. Herpes simplex thymidine kinase (HStk) transduceddonor lymphocytes induce anti-lymphoma response. Molecular Therapy Vol 1, No 5, $239, 2000.

36. Seregina T, Link CI, Butt RK, Traynor AE, Taylor C, Burns WH, Rosen ST, Edleman M, Christensen E, Drobyski WR. Useof HSVtk/GCV system as a "safety feature" to control graft versus host disease in patients receiving adoptiveimmunotherapy for treatment of hematologic disorders. Molecular Therapy Vol 1, No 5, $270, 2000.

37. Butt RK, Cohen BA, Lobeck LI, Oyama Y, Traynor A, and Burns WH.* Immune suppressive therapy with autologoushematopoietic stem cell transplantation arrests active CNS inflammation but not axonal atrophy in patients withsevere disability and progressive multiple sclerosis. Blood Vo198 (11), 2001, p687a (abst 2871)

38. Butt RK, Oyama Y, Brush M, Rodriguez J, Traynor AE. Supplementing allogeneic bone marrow with CD34 enrichedperipheral blood cells in hematologic malignancies. Blood Vol 98 (11), 2001, p 4~L2a (abst 1731).

39. Butt RI(, Drobyski W, Seregina T, Traynor A, Oyama Y, Keever-Taylor C, Kuzel T, Burns W, Link Co Anti-tumoreffectiveness of herpes simplex thymidine kinase gene transduced donor lymphocyte infusions for relapsedhematologic malignancies following allogeneic hematopoietic stem cell transplantation. Blood Vol 98 (11), 2001, p698a (abst 2917).

40. Butt RI(, Oyama Y, Traynor AE, Brush M, Rodriquez J, Brac K Craig R Autologous hematopoietic stem celltransplantation for refractory crohn’s disease. Blood Vol 98 (11), 2001, (abst 5344).

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Page 20: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

41. Oyama Y, Cohen B, Brush M, Rodriquez J, Brush M, Traynor A, Butt RK. Engraftment syndrome: A common cause forrash and fever following autologous hematopoietic stem cell transplantation for multiple sclerosis. Blood Vol 98 (11),2001, p 199a (abst 831).

42. Muraro P, Douek D, Ingoni R, McFarland H, Butt RI(, Martin R. Immunologic mechanisms of autologous hematopoieticstem cell transplantation in multiple sclerosis. Neurolof~¥ Vol 60 (5) Suppl 1, 2003, p A435 (abst $55.003)

43. Butt RI(, Cohen BA, Lobeck L, Traynor A, Bredeson C. Autologous hematopoietic stem cell transplantation in multiplesclerosis: Importance of disease stage on outcome. Neuroloh-:~y Vol 60 (5) Suppl 1, 2003, p A150 (abst P02.137)

44. Traynor A, Barr W, Rosa R, Ahya S, Corbridge T, Oyama Y, Rodriquez J, Butt R. Hematopoietic stem celltransplantation for severe SLE: Outcome of 28 patients transplanted over 6 years. Bone Marrow Transplantation Vol31, Suppl 1, 2003 page-S13 (abst 0151)

45. Butt R, Craig R, Traynor A, Oyama Y. Autologous hematopoietic stem cell transplantation of Crohn’s disease. BoneMarrow Transplantation Vol 31, Suppl 1, 2003 page-S14 (abst 0153)

46. Oyama Y, Barr W, Cohen R, Rosa R, Craig R, Brieva A, Bredeson C, Lobeck L, Butt I{. Treatment related and overallmortality in patients undergoing autologous hematopoietic stem cell transplantation for autoimmune diseases. BoneMarrow Transplantation Vol 31, Suppl 1, 2003 page-S100 (abst P476)

47. Butt R, Oyama Y, Barr W, Traynor A. AIIogeneic non-myeloablative stem cell transplantation for refractoryrheumatoid arthritis. Bone Marrow Transplantation Vo131, Suppl 1, 2003 page-S145 (abst P583)

48. Oyama Y, Traynor E, Craig R, Barr W, Rosa R, Butt R. Treatment related and overall mortality in patients undergoinghematopoietic stem cell transplantation for autoimmune diseases, a single center experience. Blood vol 102(11),p.986a, 2003.

49. Butt RK, Verda L, Kim AN, Luo K, Oyama Y. Embryonic stem cells as an alternate marrow donor source. Blood vol102(11), p.76a, 2003.

50. Verda L, Kim AN, Kohm A, Miller SD, Butt RI(. Influence of different cytokines on autoimmune disease: usingexperimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. Blood vol 102(11), p.397b, 2003.

51. Luo K, Verda L, Kim DA00yama Y, Butt RK. G-CSF mobilization in relapsing experimental autoimmuneencephalomyelitis: Benefit or disadvantage. Blood vol 102(11), p.397b, 2003.

52. Verda L, Kim DA, Villa M, Traynor AE, Oyama Y, Butt RK. Purification of peripheral blood stem cells in patients withautoimmune diseases. Blood vol 102(11), p.422b, 2003.

53. Butt RI(, Oyama Y, Traynor A, Verda L, Barr W. Complete remission of rheumatoid arthritis following allogeneichematopoietic transplantation induced mixed chimerism. Blood vol 102(11), p.468b, 2003.

54. Verda L, Kim DA, Villa M, Oyama Y, Traynor A, Butt RE. Peripheral blood stem cell mobilization in patients withautoimmune diseases. Blood vol 102(11), p.416b, 2003.

55. Butt RI(, Oyama Y, Traynor A, Craig R. Clinical remission of refractory crohn disease following autologoushematopoietic stem cell transplantation. Blood vol 102(11), p.486b, 2003.

56. Butt RE, Oyama Y, Statkute L, Krosnjar N, Verda L, Kowalska B, Traynor AE. Autologous non-myeloablativehematopoietic stem cell transplantation(NST) for severe lupus erythematosus. Blood vol 104, No 11, p46a, 2004.

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57. Oyama Y, Crai8 R, Traynor AE, Burr RK, Statkute, L. Autolol~ous hematopoietic stem cell transplantation in patientswith severe and refractory crohn’s disease. Blood vol 104, No 11, p519a, 2004.

58. Statkute L, Butt RI(, Oyama Y, Verda L, Krosnjar N, Traynor AE. Antiphospholipid syndrome in patients with systemiclupus erythematosus treated by autolo~ous hematopoietic stem cell transplantation. Blood vol 104, No 11, p520a,2004.

59. Burr RK, Verda L, Kim D, Statkute L, Oyama Y, Krosnjar N, Ikehara S, Embryonic stemc ell transplant (ESCT)-derivedmixed hematopoietic chimerism prevents diabetes in NOD mice. Blood vo1104, No 11, p587a, 2004.

60. Verda L, Luo K, Han X, Wasserstrom J, Kowalska B, Burr RI(. Effect of G-CSF and intramyocardial injection of bonemarrow cells on cardiac function in mouse model of myocardial infarction: a word for vasculo~enesis. Blood vol 104,No :~1, p735a, 2004.

6:~. Pearce WH, Burr R, Rodri~uez HE. The use of stem cells in the treatment of inoperable limb ischemia. Perspect VascSurl~ Endovasc Ther. 2008 Mar;20(1):45-7. Epub 2008 Apr 2.

62. Burr RI(. Cohen B, Stefoski D, Balabanov R, katsumakis G, Rose JW, Muraro P0 Storek J, Voltarelli J. World Conl~ress ofTreatment and Research in Multiple Sclerosis. " Autologous non-myeloablative hematopoietic stem celltransplantation for relapsin~ remittin~ multiple sclerosis. Montreal, Canada April 24th, 2008.

63. Burr RK, Bucha J, Milanetti A, Crail~ R Autolo~osu HSCT for Crohn’s disease. EBMT, Gotenborl~, Sweden, March 29th,

2009.

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Page 22: CURRICULUM VITAE - WordPress.com · CURRICULUM VITAE Richard K. Burt, M.D. 680 North Lake Shore Drive, #2400 Tower Chicago, IL. 60611 Home Phone: 312-266-0341 Office Phone: 312-908-5400

INVITED SPEAKER PRESENTATIONS (not complete list):

1. Northwestern Cancer Center State of the Art: "BMT for Autoimmune Disease", Chicago, III, 1995.

2. Northwestern Cancer Center State of the Art: "Lymphocyte Infusions, Genetic Manipulation, and ImmunologicEngineering. Chicago, III, 1995

3. Michigan State, GRAMEC City wide Internal Medicine Visiting Professor: "BMT for Autoimmune Disease", GrandRapids, Michigan, September, 1995.

4. Multiple Sclerosis Society of Chicago, "BMT for Multiple Sclerosis", Chicago, III, April, 1995.

5. Advances in Internal Medicine, National Center for Advanced Medical Education, Chicago, III, November 7, 1995,"BMT for Immunologic Diseases".

6. National Institutes of Arthritis and Musculoskeletal Disease, National Institutes of Health, Clinical Grand Rounds,"BMT for Autoimmune Diseases", Bethesda, Maryland, February 9, 1996.

7. Northwestern Allergy Immunology Division, "GVHD’, Chicago, III, February 13, 1996.

8. Northwestern Medical Grand Rounds, "BMT for Autoimmune Disease", Chicago, III, March 1, 1996.

9. Lurie Cancer Center Spring Retreat, "Adoptive Immunotherapy for Leukemia: Donor Lymphocytes Transduced withthe Herpes Simplex Thymidine Kinase Gene for Remission Induction", Evanston, III, March 23, 1996.

10. Fourth International Symposium on Blood Cell Transplantation, Adelaide, Australia. "Bone Marrow Transplant forAutoimmune Disease", March 27, 1996,

11. Twenty-third Annual Meeting European Group for Blood and Marrow Transplantation, "Bone MarrowTransplantation for autoimmune diseases". Aix-le-Baus, France, 1997.

12. Twenty-fourth Annual Meeting European Group for Blood and Marrow Transplantation, "Stem Cell therapy ofAutoimmune diseases". Courmayeur, Italy, 1998.

13. Sixth International Symposium on Recent Advances in Hematopoietic Stem Cell Transplantation, "Stem Cell Therapy:Frontiers ", San Diego, April 16, 1998.

14. Yale Spring Transplant Symposium, "BMT for SADS", New Haven, Connecticut, March 2,1998.

15. Un Versitat Hamburg, Hamburg, Germany, "BMT for Multiple Sclerosis", Neurology Grand Rounds, October, 1997.

16. Roswell Park Cancer Institute. Medical Grand Rounds, "New Advances in BMT", December 19, 1997.

17. Keystone IBMTR Symposium, "BMT for Autoimmune Diseases", Keystone, Colorado, January, 1998.

18. Mount Sinai Medical Center, New York, New York. "New Therapies in MS", Neurology Grand Rounds, February 23,1998.

19. Rush Medical Center. Oncology Grand Rounds, "Advances in Stem Cell Therapy", Chicago, III, February, 1998.

20. Mount Sinai Medical Center, New York, New York. "Transplantation for Autoimmune Disease", Hematology GrandRounds, March 12, 1998.

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21. West Virginia University Morgantown. "New Strategies in Transplantation". Hematology Oncology Grand Rounds,February, 1998.

22. Hematopoietic Stem Cell Therapy in Multiple Sclerosis. Florence, Italy, March 20, 1998.

23. Silver Cross Hospital, Chicago, Illinois, "AIIogeneic Blood and Marrow Transplant", Medical Grand Rounds, April 22,1999.

24. Cornell University Medical Center, New York, New York, "Role of Transplantation in Autoimmune Disorders", April 13,1999.

25. Twenty-fifth Annual Meeting of European Group for Blood and Marrow Transplantation. Hamburg, Germany. "Roleof Hematopoietic Transplantation in Multiple Sclerosis", March 24, 1999.

26. Federation of Special Care Organizations in Dentistry. "Medical Management of Hematologic malignancies."Chicago, Illinois, March 27, 1999.

27. University of Maryland School of Medicine, "Prospects for New Therapies in Multiple Sclerosis": Baltimore, Maryland,November 13, 1998.

28. Hinsdale Hospital Grand Rounds. "Bone Marrow Transplantation in Autoimmune Disorders". Chicago, Illinois,February 25, 1999.

29. South Texas Cancer Institute. "Stem Cell Transplantation of Autoimmune Disorders". San Antonio, Texas, February23, 1999

30. University of Heidelberg. "Hematopoietic Transplantation of Autoimmune Diseases". Heidelberg, Germany, August21, 1998.

31. Gaiter Carriage House, Northwestern Memorial Hospital. Stem Cell Transplant Seminar, April 12, 1999,

32. University of Texas, Southwestern. "New Advances in Stem Cell Transplantation of Autoimmune diseases". Dallas,Texas, January 25, 1999.

33. Swedish Convenant Hospital. "Acute Myelogenous Leukemia". Chicago, Illinois, January 13, 1999.

34. Organ Health Science University, School of Medicine. "Stem Cell Transplantation". Portland, Oregon, September 18,1998.

35. St. Vincent-Mercy Medical Center. "Advances in Stem Cell Transplantation". Toledo, Ohio, March 3, 1998.

36. M.D. Anderson Cancer Center. "Adoptive Immunotherapy using HSTK Transduced Lymphocytes". Houston, Texas,October 1, 1998.

37. Leukemia Society of America. "Adoptive Immunotherapy with HSTK Transduced Donor Lymphocytes". Washington,D.C., September 24, 1998.

38. University of California, Los Angeles. "Hematopoietic Stem Cell Transplantation of Autoimmune Disease". LosAngeles, California, November 4, 1998.

39. European Bone Marrow Transplant, and European League Against Rheumatism. "Hematopoietic Stem Cell Therapy inAutoimmune Diseases". October 9, 1998, Basel Switzerland.

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40. University of Oklahoma. "Stem Cell Transplantation". Oklahoma City, Oklahoma, December 166, 1998.

41. National Institutes of Health. "Advances in Autoimmune Diseases". Bethesda, Maryland, May 10, 1999.

42. American Society of Hematology, Educational Session, "Evolving Role of Hematopoietic Stem Cell Transplantation inAutoimmune Diseases". Miami Beach, Florida, December 4, 1998.

43. 25th Annual Meeting European Group for Blood and Marrow Transplantation & 15th Meeting of the Nurses Group,"Transplant Immunolo~/". Hamburg, Germany, March 21-24, 1999.

44. Northwestern University School of Medicine, Medical Grand Rounds, "Hematopoietic Transplants Using GeneticallyModified Cells", Chicago, III, April 15, 1999.

45. The New York Presbyterian Hospital, Cornell Medical Center, "High-Dose Chemotherapy for Autologous Bone MarrowTransplantation in Autoimmune Diseases", New York, New York, April 13, 1999.

46. CME Lecture for Silver Cross Hospital, AIIogeneic Blood and Marrow Transplantation, Silver Cross Hospital, Joliet, II,April 22, 1999

47. Yale University. "Hematopoietic Transplantation Using Genetically Modified Cells". New Haven, Connecticut. May 3,1999.

48. People’s Republic of China, Nanjing University, Roundtable Discussion of Transplantation for Severe AutoimmuneDisease, Nanjing, Peoples Republic of China, May 26, 1999.

49. Amgen Medical Education Services, "Autologous Stem Cell Transplantation for Autoimmune Diseases and MultipleSclerosis", Palmetto Richland Memorial Hospital, Columbia, South Carolina, June 3, 1999.

50. Northwestern University Medical School, Division of Rheumatology, Grand Rounds, "The Role of Bone MarrowTransplantation in Autoimmune Diseases", June 9, 1999.

51. 4th Meeting of the European Hematology Association, "Mobilization of PBPC in Autoimmune Disease", Barcelona,Spain, June 10, 1999.

52. Medical grand rounds, Fred Hutchinson Cancer Research Center, "High Dose Strategies in Autoimmune Disorders",Seattle, WA, June 25, 1999.

53. 28th Annual Meeting of the International Society of Experimental Hematology, "New Intense ImmunosuppressiveApproaches to the Treatment of Severe Autoimmune Diseases", Monteo Carlo, Principality of Monaco, July 10-14,1999.

54. Hemostasis and Thrombosis Workshop, and the International Symposium, "Hematopoietic cell Transplantation inMultiple Sclerosis and Rheumatoid Arthritis", Medico Nacional La Raza, Mexico City, August 27, 1999.

55. Xl International Congress of EMG and Clinical Neurophysiology, "Current Aspects of Pathogenesis and Therapy ofMultiple Sclerosis", Prague Czech Republic, September 12-17, 1999.

56. American Association of Blood Banks, Scientific Think Tank for Transfusion Sciences, "Dose-Intensive Chemotherapywith Stem Cell Support for ITP and other Autoimmune Diseases", Ellicott City, Maryland, September 22-23, 1999.

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57. Worcester Translational Research Conference, Stem and Immune Cell Therapy for the Treatment of AutoimmuneDisease, "Bone Marrow Transplantation for the Treatment of Autoimmune Disease", Shrewsbury, MA, September 24-25, 1999.

58. 10th Anniversary Vanderbilt Transplant Center, Transplantation 2000, "Frontiers of Stem Cell transplantation: TreatingAutoimmune Disease", Nashville, Tennessee, December 1, 1999.

59. Medical Grand Rounds: Advances in HSCT, University of Illinois at Chicago, January 27, 2000.

60. Ist Interdisciplinary Symposium on the Treatment of Autoimmune Disorders, "Gene Marked AutologousHematopoietic Stem Cell Transplantation of Autoimmune Disease", Kiel, Germany, February 15, 2000.

61. American College of Rheumatology Clinical Update on new Therapies for the Rheumatic Diseases Meeting, "Stem CellReplacement in Autoimmune Diseases" in Chicago, February 18-20, 2000.

62. 26th Annual Meeting European Group for Blood and Marrow Transplantation and 16th, Educational lecture: "Stem celltherapy of autoimmune diseases". Innsbruck, Austria, March 5-8, 2000.

63. University of Miami School of Medicine, Diabetes Research Institute, "Advances in Cell and Gene Therapy", March 1,2000.

64. IBMTR/ABMTR Annual Meeting, "Autoimmune Diseases", Anaheim, California, March 26-29, 2000.

65. Clinical and Molecular Basis of Transfusion-Induced Immunomodulation, Presented by Yale University School ofMedicine, Department of Laboratory Medicine and McMaster University, Departments of Pathology and Medicine,"Stem Cell Transplantation for Autoimmune Disease", Washington, D.C., March 30-31, 2000.

66. Experimental Biology Symposium, "Bone Marrow Transplantation in Non-Malignant Diseases", San Diego, California,April 16, 2000.

67. H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, "HSCT for autoimmune diseases". April 27, 2000.

68. Med. Klinik (Rheumatologie), "Results of Hematopoietic Stem Cell Transplantation in Autoimmune Diseases", Charite,Berlin, Germany, May 7-9, 2000.

69. 8th Annual International Symposium on Recent Advances in Hematopoietic Stem Cell Transplantation, "Stem CellTransplantation, Pros and Cons", Heidelberg, Germany, May 4-6, 2000.

70. Stem Cell Biology: Potential and Promise" National Institute of Arthritis and Musculoskeletal and Skin Diseases(NIAMS) and the National Institute on Aging (NIA), National Institutes of Health, Bethesda, Maryland, June 1-2, 2000.

71. LaGrange Memorial Hospital, Continuing Medical Education Program "Bone Marrow Transplantation in AutoimmuneDisorders", LaGrange, Illinois, June 6, 2000.

72. June’s Basic Science Mini-Symposium, "Control of GVHD Using HSTK Transgeneic Lymphocytes", Rober~ H. LurieComprehensive Cancer Center of Northwestern University, Chicago, Illinois, June 7, 2000.

73. Multiple Sclerosis in the New Millennium, CMSC Annual Meeting, "The Role of Combination Therapies in multiplesclerosis", Halifax, Nova Scotia, June 22-25, 2000.

74. Tenth International Symposium on Autologous Blood & Marrow Transplantation, "Autoimmune Disease", Dallas,Texas, July 11-14, 2000.

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75. Rush Presbyterian Saint Luke’s Medical Center, "Stem Cell Transplant for Autoimmune Diseases." Chicago, IL. August17, 2000.

76. Gene Therapy and Molecular Biology International Conferences, "Adoptive Immunotherapy Using HSV-tk TransgenicLymphocytes", Island of Rhodos, Greece, August 26-31, 2000.

77. Immunohematology and Blood Transfusion, National Institutes of Health. "Transplantation for AutoimmuneDiseases", Bethesda, MD, September 14, 2000.

78. Response Oncolo~/, National Medical Director’s Meeting, "Stem Cell Transplants for Multiple Sclerosis", Scottsdale,AZ, September 15-16, 2000.

79.. 2nd International Workshop on Non-myeloablative Stem Cell Transplantation. "Induction of self-tolerance withautologous and allogeneic stem cell allografts". St. Martin, January 25, 2001.

80. Vanderbilt University Medical School, Hematolol~y/SCT Conference. "Transplants for autoimmune diseases",Nashville, TN, January 7, 2001.

81. Rel~ulation of Immunity (A2), Keystone Symposium, Colorado. "Hematopoietic stem cell transplantation ofautoimmune diseases". Keystone, Colorado, January 13, 2001.

82. New York Bone & Joint Quarterly Rheumatolo~oy Lecture for 2001, "Treatments for autoimmune diseases". NewYork, New York, February 6, 2001.

83. Research Seminars in Hematology and Stem Cell Transplant, Keystone IBMTR Meeting. "Stem cell therapy fortolerance induction in autoimmune diseases. Keystone, Colorado, February 26, 2001.

84. Sixth International lupus conference, Barcelona Spain. "Stem cell therapy for Lupus", March 24, 2001.

85. 9th International Symposium, University of California, San Diego. "Recent advances in hematopoietic stem celltransplantation", "Stem cell therapies for autoimmune disorders", San Diel~o, California. March 30, 2001.

86. Medical Grand Rounds, Western Pennsylvania Hospital. "Stem cell therapy". Pittsburgh, Penn. April 5, 2001.

87. St. Luke’s Mountain States Tumor Institute- High dose therapy and stem cell transplantation conference. "Stem celltherapies for autoimmune disorders", Boise, idaho, June 8, 2001.

88. Kieo University, "Advances in stem cell therapy", Tokyo, Japan, June 11, 2001.

89. Gene Therapy & Molecular Biology International Conference, "Herpes simplex Thymidine Kinase I~ene transduceddonor lymphocyte infusions for relapsed hematologic malignancies following allogeneic hematopoietic stem celltransplantation". Corfu, Greece, August 27, 2001.

90. Division of Rheumatology at Grand Rounds, University Hospitals Health System, University Hospitals of Cleveland. "

Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation", Cleveland, Ohio,September 27, 2001.

91. Hematopoietic stem cell therapy in autoimmune diseases, City of Hope National Medical Center.. "Controversies andfuture directions". Los Angeles, California, October 5, 2001.

92. Vl Congress of the International Xenotransplantation Association. "Stem cells and Xenotransplantation". Chicago,Illinois, September 30, 2001.

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93. Brazil Society of Immunology annual meeting. "Stem cell therapy". Sao Paulo, Brazil and Campos De Jordao, Brazil,October 9-12, 2001.

94. United States Department of Defense, TCAD Workshop Agenda: DARPA Tissue CAD Technologies Workshop."Plasticity of Adult Stem Cells". Washinston, D.C., December 5, 2001.

95. Education Meeting "Stem Cell Transplants for Autoimmune Disease" University of California at San Diego, ThorntonHospital, La Jolla, January 8, 2002.

96. 39th Annual Year in Internal Medicine "Plasticity of Adult Stem Cells", The Drake Hotel, Chicago, Illinois, January 24,2002.

97. Teaching Course on Stem Cells "Hematopoietic Stem Cells", Northwestern University, Chicago, Illinois, January 28,2002.

98. Tandem BMT Meetings 2002 "Hematopoietic Stem Cell Transplantation, a matter of equipoise", Coronado SpringsResort, Orlando Florida, February 24, 2002.

99. AIIogeneic Conference "Plasticity of Hematopoietic stem Cells: Able to induce tolerance and repair tissue", OmahaNebraska, March 1, 2002.

100.Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis Protocol Development Meeting "Reviewof Phase I Data" National Institute of Health, Bethesda, Maryland, March :[1, 2002.

10:~.AGA at Disestive Disease Week "Stem Cell Therapy for Crohn’s Disease", San Francisco California, May 21, 2002.

102. "Stem Cell Therapy for Tolerance and Tissue Regeneration", Snowbird, Utah, June 7, 2002.

103.Baxter, "Future Interest Pertaining to transplant arena" Deerfield, Illinois, June 27, 2002.

104. 6th Brazilian Congress of the Society of Bone Marrow Transplantation "Non-malignant transplants", Rio de JanerioBrazil, August 7, 2002.

105.The 29thWorld Congress of the International Society of Hematology "Stem Cell Therapy for induction of tolerance"Seoul Korea, August 26, 2002.

106.Blue Quality Centers for Transplant (BQCT) 2002 Summit Meeting, "Advances in Stem cells" Swiss Hotel, Chicago,Illinois, September 12, 2002.

107.Baxter "Using Stem Cells to Induce Tolerance and Repair Tissues", Deerfield, Illinois, September 12, 2002.

108. National Institutes of Health, Clinical Grand Rounds "Stem Cell Transplants for Multiple Sclerosis", Bethesda,Maryland, October 1, 2002.

109.15th Annual Council Meeting NMDP "Stem Cell Transplantation new advances", Minneapolis, Minnesota, October 12,2002.

110.Stem Cell Therapies: "From Test Tube to Current Clinical Trials", Salt Lake City, University of Utah, October 19, 2002.

111. "Stem Cell Transplants for Non-malignant Disease." American Association of Blood Banks (AABB) annual meeting.Orlando Florida, October 26, 2002.

112." Stem Cell Transplants" 2002 Springfield Cancer Institute Seminar" Springfield III, October 25th 2002.

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113. "Stem cell transplants to induce tolerance" Harvard Medical School Bone Marrow Transplant conference. BostonMassachusetts, November 7th 2002

114. " Stem cell transplantation for Crohn’s disease" The Royal Hallamshire Hospital, Sheffield, England, December 15th,

2002

115. "Clinical trials using stem cells to induce tolerance" IBMTR Keystone Symposium, Keystone Colorado, Feb 2nd, 2003.

116."Frontiers in Translational Research: Regenerative Medicine" International Medical Center of Japan, Tokyo, Japan 16,2003.

117. "Stem Cell Therapy for Vasculitis", Wegner’s Granulomatosus Association, Chicago III, Feb 15th 2003.

118."Nonablative allogeneic stem cell transplants for autoimmune diseases" 4t~ International workshop on NST. Bermuda,Feb 24th, 2002.

119. "Adult Stem Cell Research" AFMR and GCRC annual meeting, Baltimore, Maryland March 15~, 2003.

120.’Recent advances in hematopoietic stem cell transplantation" 11t~ international symposium in hematopoietic stemcell transplantation. University of California, San Diego, San Diego, California, May 10th 2003.

121.’Embryonic stem cells as an alternate marrow donor source" Xllth symposium on the molecular biology ofmacrophages and dendritic cells.. Utsunomiya, Tochigi, Japan, June 20t~, 2003.

122. "Hematopoietic stem cell transplantation for Crohn’s disease" EBMT annual meeting, Istanbul0 Turkey, July 21st,

2003.

123. "Stem cell transplantation for autoimmune disease". Northwestern University Medical Center Grand Rounds.Chicago, III, Sept 2nd, 2003.

124. "Allogeneic stem cell transplantation for autoimmune diseases". IWNST 8th international workshop onautoantibodies and autoimmunity. Berlin, Germany Sept 10-14, 2003.

125.’Stem cell therapy for Crohn’s disease". Bangor, Maine, Oct 30th, 2003.

126."Stem cell therapy for lupus". Lupus Foundation of America. Denver, Colorado, Oct 11th, 2003.

127. Visiting professor, University of Sao Paulo, Brazil, Sao Paolo, and Ribeirao Preto, Brazil, Nov B-17th, 2003.

128. "Stem cell therapy for autoimmune disease". Satellite Symposium, IBMTR / ASBMT meeting. Orlando, Florida, Feb15th, 2004.

129.’Non-myeloablative stem cell transplantation for non-malignant diseases". International workshop on non-myeloablative transplantation. Atamo, Japan, Feb 21’t, 2004.

130. "Hematopoietic stem cell transplantation for autoimmune diseases". 30th Annual Meeting of the European Groupfor Blood and Marrow Transplantation. Barcelona, Spain, March 28t~, 2004.

131. "Recent advances in stem cell therapy for autoimmune disorders". Georgetown University Medical Center, CurrentTopics in Histocompatibilityfor Technologists audio conference. Washin~on, D.C., April 6t~, 2004.

132. "Hematology". Sunrise Hospital and Medical Center, Pediatric Grand Rounds, Las Vegas, Nevada, May 21’t, 2004.

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133. "New directions in BMT". Avera McKennan Transplant Journal Club, Sioux Falls, South Dakota, June 1’t, 2004.

134. "AIIogeneic blood and embryonic stem cell transplantation for autoimmune diseases". Satellite Symposium of theInternational Symposium, 15th Molecular Biology of Hematopoiesis. Kobe, Japan, August 9th, 2004.

135. "Multi-center randomized autologous non-myeloablative stem cell transplantation for systemic lupus. Foundationfor Promotion of Cancer Research, Nagoya, Japan, August 20th, 2004.

136. "HLA matched sibling and embryonic stem cell transplantation for autoimmune diseases". Foundation for Promotionof Cancer Research, Fukuoka, Japan, August 28th, 2004.

137. "Stem cell transplantation in S/E". The 11th Asian Pacific League of Associations for Rheumatology Congress, Jeju,Korea, September 14, 2004.

138. "Autologous stem cell transplantation in multiple sclerosis". The Immunotherapy of Multiple Sclerosis Conference,Salt Lake City, Utah, October 16th, 2004.

139. "Advances in stem cell therapy for autoimmune diseases". Goiania, Brazil, November 22nd, 2004.

140. "Hematopoietic stem cell transplantation for autoimmune diseases". Miltenyi Biotec/Kirin Symposium, San Diego,California, December 3rd, 2004.

141. "Cellular therapy: progressing to clinical practice". Zenalta CME, San Diego, California, December 3rd, 2004.

142. "Stem cell therapy for autoimmune diseases". Grand Rounds, U.C. Davis Medical Center, Davis, California, December16th, 2004.

143. "Stem cell transplant for autoimmune diseases". Rheumatology Grand Rounds, Northwestern Memorial Hospital,Chicago, Illinois, February 17th, 2005.

144. "Therapeutic potential and current clinical trials related to ongoing stem cell research". Southern Regional Meetings,New Orleans, Louisiana, February 26th, 2005.

145. "Gene therapy/Stem cell research". 31st Annual Meeting of the European Group for Blood and MarrowTransplantation, Prague, Czech Republic, March 21~t, 2005.

146. "Non-myeloablative regimens for MS/Northwestern experience cytoxan/CAMPATH". "Future role of allogeneic NSTin autoimmune diseases and MS". MS International Stem Cell Transplant Trial Conference, Salt Lake City, Utah, April2nd, 2005.

147. "Sizing up stem cells: Translating recent research developments into commercial opportunity". 2005 Kellogg BiotechConference, Evanston, Illinois, April 16t~, 2005.

148. "Hematopoietic stem cell transplantation for multiple sclerosis". Calumet City MS Support Group, Calumet City,Illinois, April 18th, 2005.

149. "Recent advances in therapy for autoimmune disease". Centegra Health System Spring Clinical Symposium, CrystalLake, Illinois, April 20th, 2005.

150. "Stem cell therapy for autoimmune disease". Blue Quality Centers for Transplant 2005 Summit Meeting, Chicago,Illinois, May 6th, 2005.

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151. "Stem ceil therapy for autoimmune diseases". 2005 Clinical Research Education Conference and Career Fair,Northwestern Center for Clinical Research, Chicago, illinois, May 6th, 2005.

152. "A second generation stem cell transplantation protocol for autoimmune disease. Focus on multiple sclerosis".Department of Immunology Erasmus MC, Rotterdam, Netherlands, June 16th, 2005.

153. "Adult and embryonic stem cell therapy to induce tolerance for autoimmune diseases". CellAid - ist EuropeanSymposium, Berlin, Germany, June 21st, 2005.

154. "Multiple sclerosis international stem cell transplant trial". Prague, Czechoslovakia, June 23rd, 2005.

155. "Randomized trial for multiple sclerosis". Belo Horizonte, Brazil, June 30th -July 4th, 2005.

156. "Stem cell transplantation for autoimmune diseases". Scientific Meeting, Osaka University, Osaka, Japan, July 16th,

2005.

157. "Stem cell transplantation for Crohn’s disease". Keio University, Tokyo, Japan, July 19th, 2005.

158. Rheumatology Grand Rounds. Duke University Medical Center, Durham, North Carolina, August 16th, 2005.

159. "Stem cell transplantation for peripheral vascular disease". Northwestern University Affiliated Transplant CentersCase Manager Conference, Dimensions of Transplantation Current Stem Cell Transplant Trends, Children’s MemorialInstitute for Education and Research, Chicago, Illinois, August 17th, 2005.

160. "Use of embryonic stem cells to treat autoimmune diseases". Stem Cell Research Conference, Stem Cell Researchand its Application in Therapeutics, Cambridge Health Institute, Cambridge, Massachusetts, August 31st, 2005.

161. "Embryonic stem cells as an alternative marrow donor source. Engraftment without graft vs host disease". 8th

International Conference "Gene and Drug Therapy in Molecular Medicine", Crete Island, Greece, September 6th,

2005.

162. "Effect of stem cell transplantation in morbus crohn". Scientific Symposia, Therapy of Autoimmune Diseases, Berlin,Germany, September 10th, 2005.

163. "Hematopoietic stem cell transplantation for lupus". Ginger Launey DeSalvo Foundation for Lupus Research, Olathe,Kansas, September 24th, 2005.

164. "Use of adult stem cells for tissue rejuvenation". Truman College, Chicago, Illinois, September 27th, 2005.

165. "Lymphoablation for autoimmune disorders". IDO Inhibitors Symposium, New Link Genetics, Safety Harbor, Florida,October 14th, 2005.

166. "AutoIogous hematopoietic stem cell transplantation for autoimmune disease". Keystone Symposia Meeting,Singapore General Hospital, Singapore, October 26th, 2005.

167. "AIIogeneic hematopoietic stem cell transplantation and embryonic stem cell transplantation for autoimmunedisease". Keystone Symposia Meeting, Singapore General Hospital, Singapore, October 27tu, 2005.

168. "Stem cell transplantation for multiple sclerosis", Baylor College of Medicine, Cell and Gene Therapy Seminar,Houston, Texas, November 8tu, 2005.

169. "Randomized controlled trials of stem cell transplantation for autoimmune diseases", Bone Marrow TransplantConference, Harvard Medical School, Boston, Massachusetts, November 10tu, 2005.

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170. "Hematopoietic stem cell transplantation for multiple sclerosis". Sykehuset Telemark, Skien, Norwegian MultipleSclerosis Competence Centre, Sandefjord, Norway, November 15th, 2005.

171."Stem Cell Transplantation for Autoimmune Diseases", Moores USDC Cancer Center, LaJolla, California, December2nd, 2005.

172. "Stem Cell Transplantation for Autoimmune Diseases" University of Colorado Health Sciences Center, Denver,Colorado, January 10th, 2006.

173. "Stem Cell Transplantation for Autoimmune Diseases: matched sibling allogeneic HSCT and (ESC) transplant forautoimmune diseases", Keio University School of Medicine, Koyasu laboratory, Tokyo, Japan, January 13th, 2006.

174."AIIogeneic Hematopoietic Stem Cell Transplantation for Autoimmune Disease: Graft Versus Autoimmune Disease(GVA) without Graft Versus Host Disease (GVHD), Keio University International Symposium on Stem Cell Biology andRegenerative Medicine - from Bench to Bedside, Tokyo, Japan, January 14th, 2006.

175. "Stem Cell Therapy for Autoimmune Diseases", Sarasota Memorial Hospital Grand Rounds, Sarasota, Florida,February 3rd, 2006.

176. "Stem cells of the hematopoietic system: a plastic model", Northwestern University, Chicago, Illinois, March 6th,

2006.

177. "Immunotherapy for collagen and vascular disease" Bench to Bedside, Northwestern University, Chicago, lllinois,March 15t", 2006.

178. "The Use of Adult Stem Cells to Treat Disease in Humans", Experimental Biology/2006, San Francisco, California, April2nd, 2006.

179. "Stem Cell Transplantation for Autoimmune Diseases", Hematology Grand Rounds, Vanderbilt-lngram Cancer Center,Vanderbilt University School of Medicine, Nashville, Tennessee, May 3rd, 2006.

180. "Bone Marrow Transplant for Crohn’s Disease", University of Calgary, Calgary, Alberta, Canada, May 16th, 2006.

181. "Hematopoietic stem cell transplantation for patients with autoimmune diseases", The Affiliated Drum TowerHospital of Nanjing University Medical School, Nanjing, China, June 24th, 2006.

182. "Stem Cell Transplantation for Autoimmune Diseases", The Evanston Hospital Multiple Sclerosis Support Group,Evanston, Illinois, July 19t~, 2006.

183. "Division of Immunotherapy for Autoimmune Diseases", Michael Reese Hospital Grand Rounds, Chicago, Illinois,August 3rd, 2006.

184."Stem cell transplantation for autoimmune diseases", 9~ International Conference on "Drul~ and Gene-basedTherapeutics", Agia Pelagia, Heraklion, island of Crete, Greece, September 3rd, 2006.

185."Allogeneic and embryonic stem cell transplantation in AID", Ist International Symposium on Stem Cells, Cell Therapyfor Autoimmune and Inflammatory Diseases, Salvador, Bahia, Brazil, September 15th, 3006.

186."Hematopoietic stem cell transplantation for autoimmune diseases", Washington University School of MedicineDivision of Rheumatology Grand Rounds, St. Louis, Missouri, October 19th, 2006.

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187. "Autologous Non-Myeloablative Peripheral Blood Stem Cell Transplantation in Patients with Systemic Sclerosis",American College of Rheumatology, 2006 ACR/ARHP Annual Scientific Meeting, Washington, DC, November 12th,

2006.

188."HSC-i- for Autoimmune Diseases", NUATC Stem Cell -IX Conference, Northwestern Memorial Hospital, Chicago,lllinois, December 6th, 2006.

189."Stem Cell Transplantation for Autoimmune Diseases", University of lllinois at Chicago, Section ofHematology/Oncology Research Seminar, Chicago, lllinois, January 18, 2007.

190. "Stem Cells in the Treatment of Disease: Therapeutic Potential and Ethical Considerations", Centegra Health System,Hot Topics in Medical Ethics, Crystal Lake, lllinois, January 24th, 2007.

191. "The promise of stem cells for lupus", The Lupus Foundation of America, 2007 Lupus Advocacy Day, Washington,D.C., March ist, 2007.

192. "Stem Cell Plasticity, Cell Therapy’, XXXl World Congress of the International Society of Hematology, Punta del Este,Uruguay, March 22nd, 2007.

193. "Type I Diabetes Mellitus and AutoBMT", NeoStem sponsored Diabetes Mellitus Retreat, New York, New York, March28th, 2007.

194. "Stem Cell Treatment of Lupus", Lupus Foundation of American-Indiana Chapter, Living Well with Lupus: ’Living aBalanced life’, Chesterton, Indiana, April 21st, 2007.

195. "Immunologic Lesson: The Growing Role of Biologic Therapies in Stem Cell Transplantation", 2007 BiologicalTherapeutics for Autoimmune Disease Symposium, Northwestern University Feinberg School of Medicine, Chicago,Illinois, April 28th, 2007.

196. "Autotansplantation in Autoimmune Diseases", Mexican Society of Hematology Annual Meeting, Acapulco, Mexico,May 3rd, 2007.

197. "Stem Cell Transplantation for Autoimmune Diseases", The Lupus Foundation of America Indiana Chapter, PhysiciansDinner & Lecture, Merrillville, Indiana, May 23rd, 2007.

198. "HSCT for LSE", The Lupus Foundation of America, Texas Gulf Coast Chapter, Houston, Texas, June 26th, 2007.

199. "HSCT for Rheumatic Diseases: International Experience", "HSCT for Autoimmune Diseases -- Past, Present andFuture", "New Protocols of Cellular Therapy for Inflammatory and Degenerative Diseases", International Symposiumon HSCT, Sao Paulo, Brazil, August 3rd & 4th, 2007.

200. "Stem Cell for Autoimmune Diseases", Horizons of Medicine - XXlV National Congress of Biomedical Research,Monterrey, Mexico, September Ist, 2007.

201. "Hematopoietic Stem Cell Transplantation for Diabetes", Tubingen, Germany, September 12th, 2007.

202. "AIIogeneic and Embryonic Stem Cell Transplantation in Autoimmune Disease", II international Symposium inAdvanced Therapies and Stem Cells, Rio de Janeiro, Brazil, September 21st, 2007.

203.3rd Annual Symposium on Current Biological Therapy for Immune-mediated Diseases, University of California, Irvine,California, September 22nd, 2007.

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204. "HSCT for autoimmune diseases. What have we learned?" New York Academy of Sciences. New York, New York,Sept 25th, 2007

205.The 21st century center of excellence program. "Novel BMT methods for intractable diseases: From Bench to Bedside"Kansai Medical University, Osaka, Japan October 27,2007.

206. Conferencias Celulas Madre. Hospital de San Jose Fundacion Universitaria de Ciencias de la Salud Hospital InfantilUniversitario de San Jose. "HSC and ESC transplants for autoimmune diseases". Bogota, Columbia Nov 8th, 2007.

207.Hackensack University Medical Grand Rounds, "Stem cell transplants for autoimmune diseases". Hackensack, NJ Nov14th, 2007

208. Wayne State University Multiple Sclerosis Symposium. " Hematopoietic stem cell transplantation for MS". Detroit,Michigan Nov 16th, 2007.

209.Grace and Grove for Scleroderma. "Hematopoietic stem cell transplant for systemic sclerosis" Milwaukee, Wisconsin.Nov 24th, 2007

210. Sirio Libanes Hospital. "Stem cell therapy for MS and SLE" Sao Paolo, Brasil, Nov 28, 2007.

211.Eight Annual Rachael Levine Diabetes and Obesity Symposium. Translational Research in Type 1 Diabetes. BeyondInsulin and the Edmonton Protocol. "Hematopoietic stem cell transplantation for Type 1 diabetes". Newport Beach,California. January 26th, 2008

212. Northwestern University Alumni club of Naples. "Stem cells for autoimmune diseases" Naples, Florida, Jan 26, 2008.

213. Congress of the United States, House of Representatives. HC-9 US Capital. "Stem cell treatments and advancingscience" Washington DC, March 12, 2008.

214.New York University School of Medicine, Division of Endocrinology, Diabetes and Metabolism. " Hematopoietic stemcell transplantation for Type 1 Diabetes." March 27, 2008.

215. Central Society for Clinical Research. "Stem cells transplants for autoimmune disease" Chicago, III, April 25, 2008.

216.1st annual Scleroderma patient education day. "Stem cell transplant and scleoderma" Chicago, III Sept 13th, 2008.

217. Simposio Internacional de Terapia Celular. "Cellular therapy for autoimmune diseases" Curitiba, Brasil October 1-4,2008.

218. 1’t International Congress of the Latin American Society for Cell Therapy. "Stem cell therapy for lupus." Lima, Peru,Nov 1-4, 2008.

219.5th Annual Diabetes Conference "Innovated steps changing the journey of diabetes. "Using stem, cells to treat type 1diabetes". London, UK, Feb 4th, 2009

220. East of England Stem Cell Network (EESCN). MRC Stem Cell Initiative. "Future direction of adult and embryonic stemcell therapy; an evening with Sir lan Wilmut and Richard Burr". Cambridge, UK, March 10th, 2009.

221. Ospedale Pediatrico Bambino Ges~J, Pediatric Grand rounds. " Stem cells and autoimmune disease". Rome, Italy,March 27th, 2009.

222. National Press Club. Hematopoietic stem cell transplants for type I diabetes. Washington D.C. April 14th, 2009.

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223. Sue and Bill Gross Stem Cell Institute. University of California, Irvine. Treating Diabetes with autologous stem celltherapy. June 25t", 2009

224.Academy of anti-aging medicine. "Stem cells for autoimmune diseases" San Jose, California. Sept 12th, 2009.

225.Chronic inflammatory demyelinating disease (CIDP) Stem cell therapy meeting. Ribeirao Preto, Brasil, Sept 24-26,2009

226. Monash University, HSCT for type 1 diabetes. Melbourne, Australia. Oct 13th, 2009

227. MS Research Australian (MSRA) public lecture. " HSCT for MS" Sydney, Australia, Oct 15, 2009.http://www.youtube.com/results?search query=burt+stem+cell&aq=f )

228. IX Simposio internacional trasplante de celulas progenitoras hematopoyeticas. " Stem cell transplants for systemiclupus erythematosus and scleroderma". Mexico City, Mexico. Oct 26-28, 2009.

229. Transplantace krvetvornych Bunek u autoimunitnich onemocneni. "Stem cell transplnt for autoimmune disease"Charles UniversJty, Praque (Praha) Czech Republic. Nov 18th, 2009

230.EBMT autoimmune meeting. Hematopoietic stem cell transplants for severe autoimmune diseases, Florence Italy,Nov 19-20, 2009

231.CHU Sainte-Justine Le centre Hospitalier universitaire mere-enfant. Universite de Montreal. "Stem cell transplant forinflammatory bowel disease". Montreal, Canada, Jan 11-12, 2010.

232.Scripps Clinic Medical Grand Rounds. "HSCT for autoimmune disease". La Jolla, California Feb 3rd, 2010.

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