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Current Opinion in Immunology 1999, 11:648–656
This review contains a misleading statement: “mice withmyeloid-specific deficiency of Stat3…exhibit an inability toproduce several Stat3-dependent cytokines, most notablyIL-10…[26••].” Rather than an inability to produce IL-10,such mice exhibit an inability to respond to IL-10.
The reference was also incorrectly cited and should haveappeared as shown below.
26. Takeda K, Clausen BE, Kaisho T, Tsujimura T, Terada T, Förster I, Akira S: •• Enhanced Th1 activity and development of chronic enterocolitis in
mice devoid of Stat3 in macrophages and neutrophils. Immunity1999, 10:39-49.
In this model, the loss of Stat3 in myeloid cells leads to an activated pheno-type of macrophages and consequently colitis, raising the possibility that pri-mary defects in macrophages and other myeloid cells may be sufficient toinitiate colitis.
CorrigendumAnimal models of mucosal inflammation and their relation tohuman inflammatory bowel diseaseRichard S Blumberg, Lawrence J Saubermann and Warren Strober
imc218.qxd 02/24/2000 12:13 Page 226
