2
CME examination Identification No. 880-107 See "Instructions for Category I CME Credit" on page 23A of the front advertising section. Questions 1-33, Sams WM Jr: J AM ACAD DERMATOL 3:1-13, 1980.) Directions for questions 1-10: Give single best re- sponse. 1. Allergic vasculitis is most likely a disease of a. cellular immunity b. immune complexes c. cytotoxic antibodies d. anaphylaxis e. defective chemotaxis 2. Allergic vasculitis tends to develop when the rela- tive amount of the responsible antigen to its anti- body (antigen: antibody) in the blood is a. much greater than 1: 1 b. slightly greater than 1: 1 c. equal d. slightly less than 1: 1 e. much less than 1: 1 3. Neutrophil chemotaxis in allergic vasculitis is due primarily to a. Clq b. C3 c. C5a d. C6 e. bradykinin 4. With electron microscopy the involved vessels in allergic vasculitis appear to be a. arteries b. arterioles c. capillaries d. postcapillary venules e. veins 5. The most serious threat to the patient with allergic vasculitis is posed by involvement of the a. lungs b. heart c. kidneys d. adrenals e. brain 6. To be meaningful, within how long after formation of a lesion must immunological studies be carried out? a. 1 hour b. 4 hours c. 8 hours d. 24 hours e. 72 hours 7. Rheumatoid vasculitis is characterized by all of the following except a. mesenteric infarction b. mononeuritis multiplex c. skin infarctions d. seizures e. fever 8. What proportion of patients with the cutaneous form of polyarteritis nodosa progress to develop the systemic type? a. Over 90% b.60% c. 35% d.20% e. Few, if any 9. Dapsone, 100-300 mg daily, has been reported to be effective in the treatment of a. pityriasis Iichenoides b. Henoch-Schonlein purpura c. essential mixed cryoglobulinemia d. erythema elevatum diutinum e. temporal arteritis 10. Tetracycline has been effective in treatment of some cases of a. pityriasis Iichenoides b. Henoch-Schonlein purpura c. essential mixed cryoglobulinemia d. erythema elevatum diutinum e. temporal arteritis Directions for questions 11-15: Select the one let- tered item that is most closely related to each numbered item. a. Hypocomplementemic vasculitis b. Essential mixed cryoglobulinemia c. Henoch-Schonlein purpura d. Erythema elevatum diutinum e. Allergic granulomatous angiitis(Churg-Strauss) 11. Tends to occur in the springtime 12. Mimics asthma early in its course 13. Urticarial lesions that persist in one place for more than 24 hours 14. Lesions may resemble xanthomas 15. An associated reticulated purpura on the fingers, toes, or earlobes may occur 15

CME examination

Embed Size (px)

Citation preview

Page 1: CME examination

CME examination Identification No. 880-107

See "Instructions for Category I CME Credit" on page 23Aof the front advertising section.

Questions 1-33, Sams WM Jr: J AM ACAD DERMATOL3:1-13, 1980.)

Directions for questions 1-10: Give single best re­sponse.

1. Allergic vasculitis is most likely a disease ofa. cellular immunityb. immune complexesc. cytotoxic antibodiesd. anaphylaxise. defective chemotaxis

2. Allergic vasculitis tends to develop when the rela­tive amount of the responsible antigen to its anti­body (antigen: antibody) in the blood isa. much greater than 1: 1b. slightly greater than 1: 1c. equald. slightly less than 1: 1e. much less than 1: 1

3. Neutrophil chemotaxis in allergic vasculitis is dueprimarily toa. Clqb. C3c. C5ad. C6e. bradykinin

4. With electron microscopy the involved vessels inallergic vasculitis appear to bea. arteriesb. arteriolesc. capillariesd. postcapillary venulese. veins

5. The most serious threat to the patient with allergicvasculitis is posed by involvement of thea. lungsb. heartc. kidneysd. adrenalse. brain

6. To be meaningful, within how long after formationof a lesion must immunological studies be carriedout?a. 1 hourb. 4 hoursc. 8 hoursd. 24 hourse. 72 hours

7. Rheumatoid vasculitis is characterized by all of thefollowing excepta. mesenteric infarctionb. mononeuritis multiplexc. skin infarctionsd. seizurese. fever

8. What proportion of patients with the cutaneousform of polyarteritis nodosa progress to developthe systemic type?a. Over 90%b.60%c. 35%d.20%e. Few, if any

9. Dapsone, 100-300 mg daily, has been reported tobe effective in the treatment ofa. pityriasis Iichenoidesb. Henoch-Schonlein purpurac. essential mixed cryoglobulinemiad. erythema elevatum diutinume. temporal arteritis

10. Tetracycline has been effective in treatment ofsome cases ofa. pityriasis Iichenoidesb. Henoch-Schonlein purpurac. essential mixed cryoglobulinemiad. erythema elevatum diutinume. temporal arteritis

Directions for questions 11-15: Select the one let­tered item that is most closely related to eachnumbered item.

a. Hypocomplementemic vasculitisb. Essential mixed cryoglobulinemiac. Henoch-Schonlein purpurad. Erythema elevatum diutinume. Allergic granulomatous angiitis (Churg-Strauss)

11. Tends to occur in the springtime12. Mimics asthma early in its course13. Urticarial lesions that persist in one place for more

than 24 hours14. Lesions may resemble xanthomas15. An associated reticulated purpura on the fingers,

toes, or earlobes may occur

15

Page 2: CME examination

16 CME examination

Directions for questions i 6-20: Select the one let­tered item that is most closely related to eachnumbered item.

a. Essential mixed cryoglobulinemiab. Henoch-Schonlein purpurac. Erythema elevatum diutinumd. Lymphomatoid granulomatosise. Hypergammaglobulinemic purpura (Walden­

strom)16. The antigen is an immunoglobulin to which an­

other immunoglobulin has become an antibody17. There is suggestive evidence that the antigen may

be a streptococcus18. There is a particular association with hepatitis B

infection19. Tends to follow an upper respiratory infection20. Deposition of IgA in vessel walls has been found

in a high proportion of patients studied

Directions for questions 2i -25: Select the one let­tered item that is most closely related to eachnumbered item.

a. Leukocytoclastic vasculitisb. Rheumatic vasculitisc. Granulomatous vasculitisd. Polyarteritis nodosae. Giant cell arteritis

21. Erythema elevatum diutinum22. Takayasu's disease23. Necrobiosis lipoidica diabeticorum24. Temporal mixed arteritis25. Essential mixed cryoglobulinemia

Directions for questions 26-28: For each num­bered item choose the appropriate lettered item.

a. Wegener's granulomatosisb. Lymphomatoid granulomatosisc. Bothd. Neither

26. Involves the upper respiratory tract and kidneys27. Glomerulitis tends not to be present28. Treatment with cyclophosphamide is usually ef­fective

Journal of theAmerican Academy of

Dermatology

Directions for questions 29-33: indicate correctallswers. All, some, or noneofthe choices may betrue.29. Allergic vasculitis may present with

a. palpable purpurab. nonpalpable purpurac. hemorrhagic bullaed. ulcerationse. nodules

30. Which of the following are characteristic his­topathologic features of allergic vasculitis?a. Nuclear dustb. Fibrinoid necrosisc. Thickened vessel wallsd. Hemorrhagee. An inflammatory infiltrate composed only of

lymphocytes in some cases31. At the time of initial diagnosis of allergic vas­

culitis, which of the following tests should be per­formed?a. Examination of urine for microscopic hematuriab. Examination of urine for proteinuriac. Quantitative 24-hour urinary protein determi­

nationd. Creatinine clearance teste. Renal biopsy

32. Drugs that have been implicated in the etiology ofallergic vasculitis includea. aspirinb. iodidesc. penicillind. phenothiazinese. sulfonamides

33. Appropriate treatment of allergic vasculitis mightincludea. aspirinb. antihistaminesc. prednisoned. cyclophosphamidee. nothing