Chapter1 transportation

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    Chapter 1

    TRANSPORT

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    1.1 THE IMPORTANCE OF

    TRANSPORT SYSTEM IN

    MULTICELLULAR ORGANISMS Exchange of gases and substances

    occurs across the plasma membrane of

    the cells by diffusion.

    In unicellular organisms, there is no

    problem in obtaining the cell requirementsand removing the waste products bydiffusion. This is because diffusion caneasily occur across the plasma

    membrane.

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    Unicellular organisms such as amoeba sp.

    are small in size. They have a large total

    surface area to volume (TSA/V) ratio. This

    enables the exchange of substances to

    occur rapidly by diffusion.

    Multicellular organism are bigger and more

    complex. The cells cannot depend on

    diffusion alone to obtain its cellrequirements.

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    The problems faced by multicellularorganisms in sustaining lives are:

    a) large body size organisms have a smalltotal surface area to volume (TSA/V) ratio.

    As a result, the rate of diffusion ofsubstances is low.

    b) as the size of an organism increases, theamount of cell requirements and metabolicwaste product also increases. So, diffusionalone is not sufficient.

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    To overcome these problem, multicellularorganisms such as humans, animals and

    plants need special transport systems totransport the nutrients to all the body cellsand to remove all the metabolic wasteproduct from the body cells.

    The transport system in humans andanimal is the blood circulatory system.

    In plant, the transport system is thevascular tissues which consist of xylemtissues and phloem tissues.

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    1.2 THE CONCEPT OF

    CIRCULATORY SYSTEM The circulatory system in human and

    animal consists of :

    a) Bloodb) Blood vessels

    c) Heart

    The medium of transport in human and

    animals is the blood which flows in the

    circulatory system.

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    Composition of human blood Blood is a connective tissue in liquid form.

    The human blood is made up of 55% plasma and

    45% blood cells.

    There are three types of blood cells:

    a) Erythrocytes b) leucocytes c) platelets

    Plasma is the liquid part of the blood. It is pale

    yellowish in colour and contains various dissolved

    substances.

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    BLOOD

    Blood cells 45% Plasma 55%

    Water (90-92%)erythrocyte Dissolve substancesplatelet

    Digested food

    leucocyte

    Excretory products

    Mineral salts

    vitamins

    hormones

    Plasma protein

    Dissolved gases

    granulocyte agranulocyte

    neutrophil

    eosinophil

    basophil

    monocytelymphocyte

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    Erythrocyte (red blood cells)

    Biconcave disc-the shaped with an elasticmembrane.

    The biconcave disc- shaped increases theTSA/V ratio to facilitate exchange of gasesby diffusion across the membrane.

    The elastic membrane enables theerythrocyte to change its shape so that itca squeeze through the narrow blood

    capillary.

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    Matured erythrocyte does not have nucleus. Thisenables the erythrocyte to contain more haemoglobin tocarry more oxygen.

    Erythrocytes are produced in the bone marrow.

    Erythrocytes survive for about 120 days and are then

    destroyed in the spleen and liver.

    Each erythrocyte contains haemoglobin which is arespiratory pigment containing iron and causes the bloodto be red in colour.

    Haemoglobin is responsible for the transport of oxygenin the form of oxyhaemoglobin and carbon dioxide in theform of carbaminohaemoglobin.

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    Leucocyte (white blood cell)

    Has a nucleus and has no fixed shaped.

    The number of leucocytes in the blood is lesser

    than the erythrocytes, but its size is larger.

    The function of leucocytes is to protect the bodyfrom diseases

    There are two types of leucocytes:

    a) Granulocytes b) agranulocytes

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    Granulocytes (granular cytoplasm)

    a) Have granules in the cytoplasma

    b) Have lobed nucleus

    c) Are formed in red bone marrow

    d) There are three types of granulocytes:

    i) neutrophil

    ii) eosinophil

    iii) basophil

    Neutrophils are phagocytes which can carry outphagocytosis to engulf and digest invading bacteria.

    Eosinophils function in regulating the allergicresponses.

    Basophils produce heparin which prevent the bloodfrom clotting

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    platelet

    Fragments of larger cells in the bone

    marrow called megacaryocytes. They

    have no nucleus.

    Platelets are involved in blood clotting.

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    Plasma Pale yellowish liquid consisting of 90% water and large

    number of dissolve substances such as:

    Blood plasma without plasma protein such asfibrinogen is called blood serum.

    a) Digested food materials such as glucose, amino acidsand fatty acids.

    b) Excretory products such as urea, uric acid andcreatinine.

    c) Minerals in the form of ions such as calcium, sodium,

    chloride, potassium, bicarbonates and vitamins.d) Dissolved gases such as carbon dioxide, oxygen and

    nitrogen.

    e) Plasma protein such as albumins, globulins andfibrinogen.

    f) hormones

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    Function of blood in transport

    1. Transport of oxygen

    2. Transport of carbon dioxide

    3. Transport of digested food, vitamins andminerals

    4. Transport of nitrogenous waste product

    5. Transport of hormones

    6. Transport of heat

    7. Transport of water

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    Transport of oxygen

    Blood transports oxygen in the form ofoxyhaemoglobin.

    In the alveolus, the partial pressure of oxygen ishigher than the partial pressure of oxygen in theblood capillary.

    Hence, the oxygen diffuses out from the alveolusinto the blood capillary around the alveolus by

    simple diffusion

    In the blood, oxygen combines withhaemoglobin in the erythrocytes to formoxyhaemoglobin.

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    Oxygen is transported in the form of

    oxyhaemoglobin to the body cells which

    lack of oxygen.

    At the body cells, oxyhaemoglobin breaks

    down to release the oxygen to the body

    cells for cell respiaration

    lungsHaemoglobin + oxygen oxyhaemoglobin

    body cells

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    Transport of carbon dioxide Carbon dioxide is transported by the blood in

    two main forms:i) ion hydrogen carbonate (ion bicarbonate) inthe blood plasma.

    ii) carbaminohaemoglobin in the

    erythrocyte

    Carbon dioxide is transported from the bodycells to the lungs to be removed duringexhalation.

    In the body cell, as a result of respiration whichrelease carbon dioxide, the partial pressure ofcarbon dioxide in the body cell is higher than

    that in the blood capillary.

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    Hence, carbon dioxide diffuse out from the bodycell into the blood capillary.

    In the blood capillary, carbon dioxide dissolvesin the blood plasma to form hydrogen carbonateion and it is transported in the blood plasma to

    the lungs.

    At the lungs, enzyme changes the hydrogencarbonate ion to carbon dioxide again.

    The carbon dioxide then diffuses out of theblood capillary into the alveolus to be removedduring exhalation.

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    Carbon dioxide can also combine with

    haemoglobin in the erythrocyte to form

    carbaminohaemoglobin which is thentransported in the erythrocytes to the

    lungs. At the alveolus,

    carbaminohaemoglobin breaks down torelease the carbon dioxide which then

    diffuse into the alveolus to be expelled out

    during respiration.

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    Transport of digested food,

    vitamins and minerals Plasma transports digested food such as simple

    sugars, amino acids, fatty acids, glycerol,vitamins and dissolve minerals.

    Digested food such as simple sugars and aminoacids, minerals and vitamin B and C areabsorbed into the blood capillaries in the villus ofthe ileum. These nutrients are then transported

    in the plasma from the ileum to the liver via thehepatic portal vein, then to the heart andsubsequently to the whole body for usage orstorage.

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    Fatty acids, glycerol, vitamins A, D, E and

    K diffuse into the lacteal of the villus and

    are transported from the ileum to thelymphatic system then back into the

    circulatory system via the left subclavicle

    vein. The food materials are thentransported in the plasma to the whole

    body.

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    Transported of nitrogenous

    waste products

    Nitrogenous wastes such as urea are by

    products of protein metabolism.

    Product of deamination of excessive

    amino acids in the liver, uric acid,

    creatinine, bilirubin and ammonium ions

    are transported by plasma to the kidneysto be excreted.

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    Transport of hormones

    Endocrine glands secrete hormones into

    the bloodstream which are then

    transported by the plasma to the targeted

    organs.

    Example, insulin hormone is transported

    by the blood plasma from the pancreas to

    the liver it acts.

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    Transport of heat

    Heat is produce during cell respiration whichoccurs actively in the muscle and liver, and alsoduring muscle contraction.

    The heat is distributed evenly throughout thewhole body by the circulatory system. Excessheat can be removed by transporting it to theskin and the lungs by the blood so that the heat

    is dissipated.

    Hence, the body temperature is maintainedaround 37C.

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    Transport of water

    Water is a universal solvent. It acts as a

    medium for all chemical reactions to take

    place in the body.

    The blood transports water to the whole

    body regulate the equilibrium of water and

    osmotic pressure in the body.