Building An OWL Ontology: Toxicological Endpoints’ Ontology Example OWL Constructs: ClassesTools --- Quick QWL –Create multiple sublasses

On the base of Leadscope ToxML schema

Building An OWL Ontology: Toxicological Endpoints’ Ontology Example OWL Constructs: Create “Organs” SuperClasse containing different subclasses on the base of GoReni

Building An OWL Ontology: Toxicological Endpoints’ Ontology Example OWL Constructs: Create “Lesions” (Effects ) SuperClasse containing different subclasses on the base of GoReni

Building An OWL Ontology: Toxicological Endpoints’ Ontology Example

Value Partitions can be created to refine our class descriptions, forexample, we will create a Value Partitions called ‘Severity Values’ Creating a ValuePartitionin OWL consists of several steps:Create sublasses:

Make the subclasses disjoint. An individualcannot be a member of more than one of them.

Create a functional property hasSeverityValue

Make a Severity Values as an Union of all subclasses

Building An OWL Ontology: Toxicological Endpoints’ Ontology Example

Disjoint classes: An individual cannot be a member of more than one of them.

‘Severity Values’ is covered by subclasses

Building An OWL Ontology: Toxicological Endpoints’ Ontology Example

OWL Properties represent relationships between two objects.Object properties: link object to object

OWL Properties

Inverse PropertiesEach object property may have a corresponding inverse property.If some property links individual a to individual b, then its inverse property will link individual b to individual a.

organs lesionshas possible lesions

Is lesion for organ

Building An OWL Ontology: Toxicological Endpoints’ Ontology Example

Property restrictions

In OWL, properties are used to create restrictions.Restrictions are used to restrict the individuals that belong to a class

Resources

• Protege Ontology Libraries– http://protegewiki.stanford.edu/index.php/

Protege_Ontology_Library• Protege tutorial– http://www.co-ode.org/resources/tutorials/

• Protege Website– http://protege.stanford.edu/doc/users.html– http://protege.stanford.edu/