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Bruno Maraviglia, Silvia Capuani, Girolamo Garreffa, Federico Giove, Tommaso Gili, Antonino M. Cassarà, Marco Carnì, Giovanni Giulietti, Marta Moraschi , Mauro Rebuzzi, Silvia De Santis MAGNETIC RESONANCE AND ITS APPLICATIONS TO THE STUDY OF BRAIN FUNCTION AND OTHER BIOLOGICAL TISSUES G1 Group @ Physics Dept , Sapienza University of Rome Marbilab @ S. Lucia Foundation , Enrico Fermi Centre

Bruno Maraviglia, Silvia Capuani, Girolamo Garreffa, Federico Giove, Tommaso Gili, Antonino M. Cassarà, Marco Carnì, Giovanni Giulietti, Marta Moraschi,

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Text of Bruno Maraviglia, Silvia Capuani, Girolamo Garreffa, Federico Giove, Tommaso Gili, Antonino M....

  • Bruno Maraviglia, Silvia Capuani, Girolamo Garreffa, Federico Giove, Tommaso Gili, Antonino M. Cassar, Marco Carn, Giovanni Giulietti, Marta Moraschi , Mauro Rebuzzi, Silvia De SantisMAGNETIC RESONANCE AND ITS APPLICATIONS TO THE STUDY OF BRAIN FUNCTION AND OTHER BIOLOGICAL TISSUESG1 Group @ Physics Dept , Sapienza University of RomeMarbilab @ S. Lucia Foundation , Enrico Fermi Centre

    G1 [email protected] / [email protected] Fermi Centre

    *RESEARCHHealthyHUMAN SCALESMALL SCALEPathologicalADSpinal fMRIP300BNCTMaterialsLBDPDncMRINeuroenergeticsMQ MRIMRI MethodsEpilepsyOSASModellingMethodsTheoryfMRSExperimentalExperimentalEEG/fMRIModellingResting state

    G1 [email protected] / [email protected] Fermi Centre

    *Neuroenergetics: experimentalJournal Cereb Blood Flow Metab 27:1055-1063 (2007)Magn Reson Imaging 24:343-348 (2006)

    G1 [email protected] / [email protected] Fermi Centre

    *Neuroenergetics: modellingJournal Cereb Blood Flow Metab, under revision

    G1 [email protected] / [email protected] Fermi Centre

    *Greicius M et al PNAS 100:253-258 (2003)Fox MD et al PNAS 102:9673-9678 (2005)Damoiseaux JS et al 103:13848-13853 (2005)

    Resting state0.01 Hz < f < 0.08 HzLow frequency intrinsic correlations during rest the default network(s)

    G1 [email protected] / [email protected] Fermi Centre

    *Resting stateCognitve modulation of the Default Mode NetworkCereb Cortex, submitted

    G1 [email protected] / [email protected] Fermi Centre

    *121086420HMCIAD543210tHealthy controls vs AD & MCI patientsRResting stateNeurology, submitted

    G1 [email protected] / [email protected] Fermi Centre

    *Spinal cord fMRINeuroimage, 42:626-634 (2008)

    G1 [email protected] / [email protected] Fermi Centre

    *Neuroimage, 41:1228-1241 (2008)Neuronal current MRIUltra Low Field NMR

    G1 [email protected] / [email protected] Fermi Centre

    *Trabecular BoneCartilageBoron Neutron Capture TherapyAdvanced MRI of biological tissuesInt J Radiat Oncol Biol Phys, 562-567 (2008).J Magn Reson Imaging, submittedBiophys J, in preparation

    G1 [email protected] / MARBILa[email protected] Fermi Centre

    *PEOPLE:RESEARCH AGREEMENTS:MAIN COLLABORATIONS:CMRR, University of Minnesota, Minneapolis, USABrigham & Women's Hospital, Boston, USAUniversity of California, Berkeley, USADipartimento di Scienze Neurologiche, Universit Sapienza, Roma, ItalyIstituto Neurologico Mediterraneo, Isernia, ItalyDipartimento di Fisica, Universit Sapienza, Roma, Italy (2 professors, 1 researcher, 3 research fellows, 2 PhD student, 1 technician)Fondazione Santa Lucia, Roma, Italy (1 researcher, 1 research fellow, MDs)RESOURCES

    G1 [email protected] / [email protected] Fermi Centre

    *3T HEAD SYSTEM (HUMAN)Siemens AllegraMagnetic field: 3TImaging Gradients: 40 mT/mBore diameter: 63 cmRFPA: 4kW (1H)System granted by:Fondazione Santa LuciaNMR Systems

    G1 [email protected] / [email protected] Fermi Centre

    *9.4T VERTICAL BORE SYSTEMBruker Avance 400Magnetic field: 9.4TDiffusion gradients: 40 mT/m Imaging gradients: 400mT/mHigh resolution Multinuclear Broad Band ObserveInsert: 5 mm-Imaging probeInsert: 5 mm (1H)Insert: 8 mm (1H,13C,23Na)Insert: 8 mm (1H,13C)

    Site granted by:Dipartimento di Fisica, Universit di Roma SapienzaNMR Systems

    G1 [email protected] / [email protected] Fermi Centre

    *Bruker BiospecMagnetic field: 7TImaging gradients: 25 mT/m Imaging gradients: 40mT/mBore diameter: 15 cmRFPA : 1kWSystem site granted by:Dipartimento di Fisica, Universit di Roma Sapienza7T HORIZONTAL BORE SYSTEMNMR Systems

    G1 [email protected] / [email protected] Fermi Centre

    *EEG DEVICEEBNeuro Mizar 4032/64 channelsSampling frequency: up to 16 kHzDynamic range: 65.5 mVMRI compatibile

    NMR Systems

    G1 [email protected] / [email protected] Fermi Centre

    *Neuronal current MRINeuroimage 39:87-106 (2008)

    G1 [email protected] / [email protected] Fermi Centre

    *Neuroimage, citedNeuronal current MRI

    G1 [email protected] / [email protected] Fermi Centre

    *

    CHECK a he servono e IPScross covariance function (positive lags) of the responsesNeuromed Modena, CMRR Neurologia