Breast cancer epidemiology

Dr Andrea MicheliDirector

Descriptive Studies and Health Planning Unit

Fondazione IRCCS "Istituto Nazionale dei Tumori"Milano

BREAST CANCER INCIDENCE

BREAST CANCER MORTALITY

COLORECTAL CANCER INCIDENCE

COLORECTAL CANCER INCIDENCE

GROSS DOMESTIC PRODUCT ANDGROSS DOMESTIC PRODUCT ANDCANCER INCIDENCE CANCER INCIDENCE

World standardised incidence rates per 100,000, GDP: ppp US $, 2006.

Fonte: GLOBOCAN 2002, IARC & United Nations (UN)

GROSS DOMESTIC PRODUCT ANDGROSS DOMESTIC PRODUCT ANDCANCER MORTALITYCANCER MORTALITY

Fonte: GLOBOCAN 2002, IARC & United Nations (UN)

World standardised mortality rates per 100,000, GDP: ppp US $, 2006.

BREAST CANCER Incidence per 100,000 - Std Eu

J. Ferlay et al. EJC 2010

Standard: ICSS

Age-standardised relative survivalAge-standardised relative survivalCONCORDCONCORD

c. Tumore della mammella - Femmine - Tutte le razze

0%

20%

40%

60%

80%

100%

0 1 2 3 4 5

Anni dalla diagnosi

So

pra

vviv

enza

rel

ativ

a (%

)

USA (Seer)

USA (Concord)

Canada

Giappone

Australia

Europa Nord

Europa Sud-Ovest

UK+Irlanda

Europa Est

8988868581

7477 76 74

67

0

10

20

30

40

50

60

70

80

90

100

15-44 45-54 55-64 65-74 75-99

Età alla diagnosi

So

pra

vviv

enza

rel

ativ

a a

5 an

ni

dal

la d

iag

no

si l

(%)

SEER

EUROCARE

Fonte: EUROCARE

Age-standardised relative survivalAge-standardised relative survivalEurope vs USAEurope vs USA

LIFE LIFE EXPECTANCY EXPECTANCY

TRENDS IN TRENDS IN EUROPEEUROPE

Fonte: United Nations Population Division

Fonte: Human Development Report 2009; Ferlay et al. 2008

GDP and standardised incidence rate for all tumours. Women

Disks are proportional to the public health expenditure ($ PPP)

Fonte: Human Development Report 2009; Ferlay et al. 2008

GDP and standardised mortality rate for all tumours. Women

BREAST CANCER incidence and mortality Italy, 1970-2010, 0-84 yrs

Grande E. et al. Regional estimates of breast cancer burden in Italy. Tumori 2007

Std EU, rate per 100,000

BREAST CANCER Mortality per 100,000 - Std Eu

J. Ferlay et al. EJC 2010

BREAST CANCER MORTALITY IN EUROPErates per 100,000 - Std Eu

WHO Mortality database

Fonte: Verdecchia A. et al. EJC 2009

5YR BREAST CANCER RELATIVE SURVIVAL ANDDEATH RISK IN EUROPE

TUMORE DELLA MAMMELLA SOPRAVVIVENZA RELATIVA A 5 ANNI DALLA DIAGNOSI

Casi diagnosticati 1995-99

Fonte: Sant M. et al. EJC 2009. EUROCARE-4

Breast cancer descriptive epidemiology data

• Mortality is decreasing

• Incidence tends to decrease in young women

• Survival is improving

• High geographical differences